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Epiphysitis of the femoral head

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https://www.readbyqxmd.com/read/27852906/assessment-of-femoral-head-revascularization-in-legg-calv%C3%A3-perthes-disease-using-serial-perfusion-mri
#1
Harry K W Kim, Jamie Burgess, Alec Thoveson, Paul Gudmundsson, Molly Dempsey, Chan-Hee Jo
BACKGROUND: Legg-Calvé-Perthes disease is a juvenile form of osteonecrosis of the femoral head. The purpose of this study was to use serial perfusion magnetic resonance imaging (MRI) to determine the pattern and rate of revascularization of the femoral heads of patients with the active stage of Legg-Calvé-Perthes disease. METHODS: We performed a prospective study of 29 patients (30 hips) with a mean age (and standard deviation) of 8.4 ± 1.9 years who were diagnosed with Waldenström Stage-1 or 2 Legg-Calvé-Perthes disease...
November 16, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27796801/the-femoro-epiphyseal-acetabular-roof-fear-index-a-new-measurement-associated-with-instability-in-borderline-hip-dysplasia
#2
Michael Wyatt, Jan Weidner, Dominik Pfluger, Martin Beck
BACKGROUND: The definition of osseous instability in radiographic borderline dysplastic hips is difficult. A reliable radiographic tool that aids decision-making-specifically, a tool that might be associated with instability-therefore would be very helpful for this group of patients. QUESTIONS/PURPOSES: (1) To compare a new radiographic measurement, which we call the Femoro-Epiphyseal Acetabular Roof (FEAR) index, with the lateral center-edge angle (LCEA) and acetabular index (AI), with respect to intra- and interobserver reliability; (2) to correlate AI, neck-shaft angle, LCEA, iliocapsularis volume, femoral antetorsion, and FEAR index with the surgical treatment received in stable and unstable borderline dysplastic hips; and (3) to assess whether the FEAR index is associated clinical instability in borderline dysplastic hips...
October 28, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27676730/multifocal-osteonecrosis-revealing-an-antiphospholipid-syndrome-case-report
#3
Sophie Legrève
OBJECTIVE: Multifocal osteonecrosis is rare. A zone of epiphyseal bone-marrow necrosis of three or more joints characterizes it. The most common risk factors are glucocorticoids intake and alcoholism. However, there is a series of other causes that could be incriminated in osteonecrosis, among which antiphospholipid syndrome. This case report, illustrates a primary antiphospholipid syndrome with only one clinical manifestation: multifocal osteonecrosis. OBSERVATIONS: A 30-year-old woman, with a medical history of left total hip replacement (THR), presents with severe right coxalgia and pain in both knees and shoulders...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27662386/capital-femoral-epiphyseal-extension-may-confer-physeal-stability-in-slipped-capital-femoral-epiphysis
#4
William Z Morris, Joshua K Napora, Keegan T Conry, Raymond W Liu
BACKGROUND: Factors including obesity and morphologic parameters around the hip that increase physeal stress are associated with an increased risk of slipped capital femoral epiphysis (SCFE). Recent evidence suggests that superior epiphyseal extension may confer stability to the physis and help protect against SCFE. The purpose of this study is to investigate the relationship between epiphyseal extension and SCFE using an age-matched and sex-matched cohort study. METHODS: We generated 2 separate cohorts for comparison: 89 patients with unilateral SCFE and 89 healthy subjects with no evidence of hip disease or deformity...
September 22, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27628762/-modified-pembersal-osteotomy-technique-with-lyophilized-human-allograft
#5
C Druschel, K Heck, C Kraft, R Placzek
OBJECTIVE: PemberSal osteotomy to improve femoral head coverage by rotating the acetabular roof ventrally and laterally. INDICATIONS: Insufficient coverage of the femoral head, and can be combined with other surgical procedures such as femoral intertrochanteric varus-derotation osteotomy and open reduction for developmental dysplasia and dislocation of the hip or to improve sphericity and containment in Legg-Calvé-Perthes disease. This specific acetabuloplasty can only be performed in patients with an open epiphyseal growth-plate...
December 2016: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/27418747/femoral-cam-deformity-due-to-anterior-capsular-force-a-theoretical-model-with-mri-and-cadaveric-correlation
#6
Cara Beth Lee, Hillard T Spencer, Kirsten F Nygaard
BACKGROUND: Cam deformity is associated with epiphyseal extension onto the anterosuperior femoral head-neck before physeal closure. A century ago, anatomists speculated that this femoral prominence acts as a pulley bar to withstand capsular compression in hip extension with pressure concentrated where the zona orbicularis (ZO) joins the iliofemoral ligament (IFL). An animal model has shown that growth plates deflect laterally and distally when exposed to forces perpendicular to growth...
December 2016: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27398645/the-fate-of-hips-that-are-conservatively-treated-in-multiple-epiphyseal-dysplasia
#7
Seung-Ju Kim, Ashok K Ramanathan, Young-Sik Jeon, Hae-Ryong Song
We reviewed the radiologic and clinical outcomes of hip joints affected by multiple epiphyseal dysplasia in 40 patients. The average patient age was 9.6 years. All patients were followed up for an average of 7.2 years. No patient underwent surgical treatment. The variances of the center-edge angle and femoral head coverage had the greatest tendency to increase with conservative treatment and follow-up (P=0.011 and 0.015, respectively). The acetabular angle and the acetabular depth index at the first visit and the latest follow-up were statistically significantly different (P=0...
July 8, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27324923/the-locomotion-of-babakotia-radofilai-inferred-from-epiphyseal-and-diaphyseal-morphology-of-the-humerus-and-femur
#8
Damiano Marchi, Christopher B Ruff, Alessio Capobianco, Katherine L Rafferty, Michael B Habib, Biren A Patel
Palaeopropithecids, or "sloth lemurs," are a diverse clade of large-bodied Malagasy subfossil primates characterized by their inferred suspensory positional behavior. The most recently discovered genus of the palaeopropithecids is Babakotia, and it has been described as more arboreal than Mesopropithecus, but less than Palaeopropithecus. In this article, the within-bone and between-bones articular and cross-sectional diaphyseal proportions of the humerus and femur of Babakotia were compared to extant lemurs, Mesopropithecus and Palaeopropithecus in order to further understand its arboreal adaptations...
September 2016: Journal of Morphology
https://www.readbyqxmd.com/read/27307364/intraoperative-monitoring-of-epiphyseal-perfusion-in-slipped-capital-femoral-epiphysis
#9
Tim Schrader, Christopher R Jones, Adam M Kaufman, Mackenzie M Herzog
BACKGROUND: The purposes of this study were to validate an innovative, percutaneous method of monitoring femoral head (epiphyseal) perfusion intraoperatively in patients with slipped capital femoral epiphysis (SCFE) and to investigate an association between intraoperative perfusion and the subsequent development of osteonecrosis. METHODS: A percutaneous screw fixation technique for SCFE was utilized. A fully threaded, cannulated, stainless-steel 7.0-mm screw was inserted into the epiphysis...
June 15, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27301232/sex-assessment-using-the-femur-and-tibia-in-medieval-skeletal-remains-from-ireland-discriminant-function-analysis
#10
Mario Novak
Sex determination based on discriminant function analysis of skeletal measurements is probably the most effective method for assessment of sex in archaeological and contemporary populations due to various reasons, but it also suffers from limitations such as population specificity. In this paper standards for sex assessment from the femur and tibia in the medieval Irish population are presented. Six femoral and six tibial measurements obtained from 56 male and 45 female skeletons were subjected to discriminant function analysis...
April 2016: Collegium Antropologicum
https://www.readbyqxmd.com/read/27278780/-treatment-of-chronic-slipped-capital-femoral-epiphysis-use-of-dynamic-epiphyseal-telescopic-screws
#11
E Schumann, D Zajonz, M Wojan, F B Kübler, P Brandmaier, C Josten, C-E Heyde, U Bühligen
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is a multifactorial structural loosening in the area through the epiphyseal plate between the epiphysis and metaphysis accompanied by slippage of the femoral head in the mid-dorsal-caudal direction without additional adequate trauma. In this retrospective study, all patients with chronic SCFE were assessed who had been treated by implanting a dynamic epiphyseal telescopic (DET) screw. METHODOLOGY: All patients who had been treated at our hospital with a DET screw implant between December 2006 and November 2014 following diagnosis of chronic SCFE were included in the study...
July 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27261966/long-term-outcomes-of-operative-and-nonoperative-treatment-of-congenital-coxa-vara
#12
David W Roberts, Yavuz Saglam, Adriana De La Rocha, Brigid N Frasquillo, Kirsten Tulchin-Francis, Harry K W Kim
BACKGROUND: Congenital coxa vara (CCV) is a rare hip condition with few long-term studies. The purpose of this study was to assess clinical, radiographic, and functional outcomes after operative and nonoperative treatment of CCV, assess reliability of radiographic parameters, and investigate risk factors for recurrence after surgery. METHODS: Retrospective review was performed of all CCV patients treated at 1 institution from 1980 to 2010. In addition, patients were recalled for additional follow-up x-rays, modified Harris Hip Score (mHHS), and gait analysis...
June 2, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27255537/asymmetric-epiphyseal-closure-of-the-femoral-head-as-a-potential-cause-of-the-primary-cam-lesion-a-case-report
#13
Yoon Je Cho, Gwang Young Jung, Eung Ju Kim, Young Soo Chun, Kee Hyung Rhyu
Cam-type femoroacetabular impingement is a pathologic condition caused by repetitive impact of the abnormal femur on a normal acetabular rim, resulting in damage to the articular cartilage. Excluding cases with known underlying diseases, the development of primary cam deformity is not well understood. Here, we describe a patient with cam-type femoroacetabular impingement exhibiting delayed epiphyseal closure at the site of the cam lesion. The authors believe that this may represent a cause of primary cam deformity, and hereby report the case with review of the literature...
September 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/27197968/short-follow-up-evaluation-of-proximal-femoral-varus-osteotomy-for-treatment-of-legg-calv%C3%A3-perthes-disease
#14
Mohamed Mansour Elzohairy
BACKGROUND: There are many methods of treating Legg-Calvé-Perthes disease, including operative and nonoperative methods. Femoral varus osteotomy is one of the surgical methods used to treat this disease, and it involves changing the alignment of the proximal femur to improve containment of the femoral epiphysis in the acetabulum. The aims of this study were to evaluate the results of femoral varus osteotomy for the treatment of Perthes disease according to various classification and grading schemes, as well as to compare the results to those obtained using other methods of treatment reported in the literature...
May 19, 2016: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/27194490/capital-femoral-growth-plate-extension-predicts-cam-morphology-in-a-longitudinal-radiographic-study
#15
William Z Morris, Douglas S Weinberg, Jeremy J Gebhart, Daniel R Cooperman, Raymond W Liu
BACKGROUND: Recent evidence has suggested that cam morphology may be related to alterations in the capital femoral growth plate during adolescence. The purpose of this study was to evaluate the relationship between capital femoral growth plate extension and cam morphology in a longitudinal radiographic study. METHODS: We used a historical, longitudinal radiographic collection to identify 96 healthy adolescents (54 boys and 42 girls) with at least 5 consecutive annual radiographs of the left hip including closure of the capital femoral physis...
May 18, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27183340/screening-of-the-col2a1-mutation-in-idiopathic-osteonecrosis-of-the-femoral-head
#16
Yuma Sakamoto, Takuaki Yamamoto, Noriko Miyake, Naomichi Matsumoto, Aritoshi Iida, Yasuharu Nakashima, Yukihide Iwamoto, Shiro Ikegawa
Idiopathic osteonecrosis of the femoral head (idiopathic ONFH) is an ischemic disorder resulting in necrosis of the subchondral bone of the femoral head. COL2A1 mutations, including c.3508G > A, have been reported to be involved in its etiology. However, the etiological role of COL2A1 mutations in idiopathic ONFH remains controversial, because the pathology of idiopathic ONFH is ischemic necrosis, not epiphyseal dysplasia usually seen in the diseases caused by COL2A1 mutations. The purpose of this study is to examine whether COL2A1 mutations have causal relation with idiopathic ONFH or not...
May 16, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/27179337/transient-epiphyseal-lesion-of-the-femoral-head-after-traumatic-hip-dislocation-a-case-report
#17
Yusuke Kubo, Takuaki Yamamoto, Goro Motomura, Satoshi Kido, Kazuyuki Karasuyama, Kazuhiko Sonoda, Yukihide Iwamoto
INTRODUCTION: We experienced a rare case in which magnetic resonance imaging (MRI) showed a transient epiphyseal lesion of the femoral head four months after traumatic hip dislocation. To our knowledge, there have been no previously published reports on the development of such transient lesions after traumatic hip dislocation involving no abnormalities just after dislocation. PRESENTATION OF CASE: We report a 22-year-old man who showed a transient epiphyseal lesion of the femoral head after traumatic hip dislocation...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27162053/femoral-head-growth-plate-dysplasia-and-fracture-in-juvenile-rabbits-induced-by-off-target-antiangiogenic-treatment
#18
A Peter Hall, T Mitchard, M G Rolf, J Stewart, P Duffy
Epiphyseal growth plate dysplasia (chondrodysplasia) might be considered as the pathognomonic feature of antiangiogenic treatment in preclinical species as it is reliably and dose-responsively induced in rodents and monkeys with vascular endothelial growth factor receptor (VEGFR) inhibitors, fibroblast growth factor (FGF) receptor inhibitors, matrix metalloproteinase inhibitors, and vascular targeting agents. Here we report epiphyseal growth plate dysplasia in juvenile rabbits treated with an oral spleen tyrosine kinase inhibitor induced by off-target antiangiogenic inhibition of VEGF and FGF family kinase receptors...
August 2016: Toxicologic Pathology
https://www.readbyqxmd.com/read/27161547/a-case-report-of-the-management-and-the-outcome-of-a-complete-epiphyseal-separation-and-dislocation-with-left-anterior-column-fracture-of-the-acetabulum
#19
Jesús Palencia, Saud Alfayez, Firas Serro, Jamal Alqahtani, Hani Alharbi, Hamed Alhinai
INTRODUCTION: Femoral head and neck fractures in children are uncommon, accounting for fewer than 1% of all pediatric fractures and fewer than 8% of all hip fractures. Furthermore, traumatic transphyseal hip fracture is rare to present in daily practice especially when associated with an acetabular fracture. PRESENTATION OF THE CASE: A twelve years old boy, not known to have any chronic illnesses, presented to the emergency department as a case of polytrauma after a road traffic accident...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27106103/disrupted-mitochondrial-function-in-the-opa3l122p-mouse-model-for-costeff-syndrome-impairs-skeletal-integrity
#20
Alice E Navein, Esther J Cooke, Jennifer R Davies, Terence G Smith, Lois H M Wells, Atsushi Ohazama, Christopher Healy, Paul T Sharpe, Sam L Evans, Bronwen A J Evans, Marcela Votruba, Timothy Wells
Mitochondrial dysfunction connects metabolic disturbance with numerous pathologies, but the significance of mitochondrial activity in bone remains unclear. We have, therefore, characterized the skeletal phenotype in the Opa3(L122P) mouse model for Costeff syndrome, in which a missense mutation of the mitochondrial membrane protein, Opa3, impairs mitochondrial activity resulting in visual and metabolic dysfunction. Although widely expressed in the developing normal mouse head, Opa3 expression was restricted after E14...
April 22, 2016: Human Molecular Genetics
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