keyword
MENU ▼
Read by QxMD icon Read
search

adhd autism

keyword
https://www.readbyqxmd.com/read/28633299/structural-covariance-networks-in-children-with-autism-or-adhd
#1
R A I Bethlehem, R Romero-Garcia, E Mak, E T Bullmore, S Baron-Cohen
Background: While autism and attention-deficit/hyperactivity disorder (ADHD) are considered distinct conditions from a diagnostic perspective, clinically they share some phenotypic features and have high comorbidity. Regardless, most studies have focused on only one condition, with considerable heterogeneity in their results. Taking a dual-condition approach might help elucidate shared and distinct neural characteristics. Method: Graph theory was used to analyse topological properties of structural covariance networks across both conditions and relative to a neurotypical (NT; n = 87) group using data from the ABIDE (autism; n = 62) and ADHD-200 datasets (ADHD; n = 69)...
June 13, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28624962/the-scope-and-nature-of-reading-comprehension-impairments-in-school-aged-children-with-higher-functioning-autism-spectrum-disorder
#2
Nancy S McIntyre, Emily J Solari, Joseph E Gonzales, Marjorie Solomon, Lindsay E Lerro, Stephanie Novotny, Tasha M Oswald, Peter C Mundy
This study of 8-16-year-olds was designed to test the hypothesis that reading comprehension impairments are part of the social communication phenotype for many higher-functioning students with autism spectrum disorder (HFASD). Students with HFASD (n = 81) were compared to those with high attention-deficit/hyperactivity disorder symptomatology (ADHD; n = 39), or typical development (TD; n = 44), on a comprehensive battery of oral language, word recognition, and reading comprehension measures. Results indicated that students with HFASD performed significantly lower on the majority of the reading and language tasks as compared to TD and ADHD groups...
June 17, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28622159/weeding-out-the-justification-for-marijuana-treatment-in-patients-with-developmental-and-behavioral-conditions
#3
Theodora Nelson, Yi Hui Liu, Kara S Bagot, Martin T Stein
Alex is a 13-year-old adolescent with high-functioning autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD)-combined type, anxiety, and depression. He has been resistant to engaging in therapy and treatment with various medications has been unsuccessful. Alex's parents are concerned about his anxiety, isolation, oppositional behaviors, academic underachievement, truancy, and substance use. A recent altercation with his stepfather led to a police intervention and a brief removal of Alex from the home...
June 15, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28614965/the-co-occurrence-of-autism-spectrum-disorder-in-children-with-adhd
#4
Benjamin Zablotsky, Matthew D Bramlett, Stephen J Blumberg
OBJECTIVE: Children with ADHD frequently present with autism spectrum disorder (ASD) symptomatology, yet there is a notable gap in the treatment needs of this subpopulation, including whether the presence of ASD may be associated with more severe ADHD symptoms. METHOD: Data from the 2014 National Survey of the Diagnosis and Treatment of ADHD and Tourette Syndrome ( n = 2,464) were used to compare children diagnosed with ADHD and ASD with children with ADHD, but not ASD...
June 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28607503/reproductive-fitness-and-genetic-risk-of-psychiatric-disorders-in-the-general-population
#5
Niamh Mullins, Andrés Ingason, Heather Porter, Jack Euesden, Alexandra Gillett, Sigurgeir Ólafsson, Daniel F Gudbjartsson, Cathryn M Lewis, Engilbert Sigurdsson, Evald Saemundsen, Ólafur Ó Gudmundsson, Michael L Frigge, Augustine Kong, Agnar Helgason, G Bragi Walters, Omar Gustafsson, Hreinn Stefansson, Kari Stefansson
The persistence of common, heritable psychiatric disorders that reduce reproductive fitness is an evolutionary paradox. Here, we investigate the selection pressures on sequence variants that predispose to schizophrenia, autism, bipolar disorder, major depression and attention deficit hyperactivity disorder (ADHD) using genomic data from 150,656 Icelanders, excluding those diagnosed with these psychiatric diseases. Polygenic risk of autism and ADHD is associated with number of children. Higher polygenic risk of autism is associated with fewer children and older age at first child whereas higher polygenic risk of ADHD is associated with having more children...
June 13, 2017: Nature Communications
https://www.readbyqxmd.com/read/28596468/-the-unitary-psychosis-theory
#6
Hiroki Kikuyama, Tetsufumi Kanazawa, Seiichiro Tarutani, Tatsushi Okayama, Hiroshi Yoneda
Since E. Kraepelin isolated schizophrenia and bipolar disorder as heterogeneous diseases, attempts to categorize mental illnesses have continued to the DSM-5. Meanwhile, cases of psychosis occurring as a result of neurosyphilis have been reported. Whilst in some cases it is useful to divide mental illnesses, in others imposing such classifications may be not be feasible. Since 2008 numerous papers have been published showing that the same genes are related to an increased incidence of several psychiatric diseases including intellectual disorder, autism, ADHD, schizophrenia, bipolar disorder, and depression...
June 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/28593620/-a-comparative-study-of-the-structural-stigmatisation-of-adhd-and-autism-spectrum-disorder-in-flemish-newspapers
#7
D Baeyens, A Moniquet, M Danckaerts, S van der Oord
Children and adults with adhd and autism spectrum disorder (asd) often find themselves being stigmatised. There is ample evidence of public stigma, but much less is known about negative coverage in the media, a phenomenon that can be regarded as a form of structural stigma.<br/> AIM: To explore the different types of structural stigma that characterise the coverage of adhd and asd in Flemish newspapers.<br/> METHOD: We used the online databases of seven Flemish newspapers in order to select articles on adhd (n=772) and asd (n=1940) published between 2010 and 2014...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28593598/brief-report-macrocephaly-phenotype-and-psychiatric-comorbidity-in-a-clinical-sample-of-mexican-children-and-adolescents-with-autism-spectrum-disorders
#8
Lilia Albores-Gallo, Laura Fritsche-García, Arturo Pabel Miranda-Aguirre, Montserrat Avila-Acosta
Autism spectrum disorders (ASD) may present with macrocephaly. Few studies have analyzed the association with psychiatric comorbidity. Participants were 94 children with any ASD with an age range from 2 to 16 years (Mdn 6 years), 82% were boys. It was found that 20% of the sample had macrocephaly and 1% microcephaly. There was no association between the presence of macrocephaly and subtype of ASD. The most associated comorbidity was attention-deficit/hyperactivity disorder (ADHD) 54.2%, followed by specific phobia 34%, dysthimia 29...
June 7, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28593597/the-stability-of-self-reported-anxiety-in-youth-with-autism-versus-adhd-or-typical-development
#9
Hillary Schiltz, Nancy McIntyre, Lindsay Swain-Lerro, Matthew Zajic, Peter Mundy
Children with autism spectrum disorder (ASD) are at risk for anxiety symptoms. Few anxiety measures are validated for individuals with ASD, and the nature of ASD raises questions about reliability of self-reported anxiety. This study examined longitudinal stability and change of self-reported anxiety in higher functioning youth with ASD (HFASD) compared to youth with symptoms of attention deficit hyperactivity disorder and typical development (TD) using the Multidimensional Anxiety Scale for Children (March, 2012; March et al...
June 7, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28588433/intragenic-cntnap2-deletions-a-bridge-too-far
#10
REVIEW
Martin Poot
Intragenic deletions of the contactin-associated protein-like 2 gene (CNTNAP2) have been found in patients with Gilles de la Tourette syndrome, intellectual disability (ID), obsessive compulsive disorder, cortical dysplasia-focal epilepsy syndrome, autism, schizophrenia, Pitt-Hopkins syndrome, stuttering, and attention deficit hyperactivity disorder. A variety of molecular mechanisms, such as loss of transcription factor binding sites and perturbation of penetrance and expressivity, have been proposed to account for the phenotypic variability resulting from CNTNAP2 mutations...
May 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/28586082/otillr%C3%A3-cklig-kunskap-om-samband-mellan-k%C3%A3-nskromosom%C3%A2-%C3%A2-avvikelser-och-psykiatriska-diagnoser-viktigt-att-barn-och-unga-utreds-och-f%C3%A3-r-r%C3%A3-tt-omh%C3%A3-ndertagande
#11
Hanna Björlin Avdic, MaiBritt Giacobini, Britt-Marie Anderlid, Ann Nordgren, Louise Frisén
Sex chromosome abnormalities are among the most common genetic changes. The manifestations vary and may include growth abnormalities, specific appearance features, and other endocrinological and physical disorders, but also delayed psychomotor development, learning disabilities, and psychiatric conditions including ADHD and autism spectrum disorders. Increased knowledge about the relationship between sex chromosome abnormalities, development and psychiatric conditions would enable improved care of these patients...
June 2, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28580294/gender-differences-in-the-structural-connectome-of-the-teenage-brain-revealed-by-generalized-q-sampling-mri
#12
Yeu-Sheng Tyan, Jan-Ray Liao, Chao-Yu Shen, Yu-Chieh Lin, Jun-Cheng Weng
The question of whether there are biological differences between male and female brains is a fraught one, and political positions and prior expectations seem to have a strong influence on the interpretation of scientific data in this field. This question is relevant to issues of gender differences in the prevalence of psychiatric conditions, including autism, attention deficit hyperactivity disorder (ADHD), Tourette's syndrome, schizophrenia, dyslexia, depression, and eating disorders. Understanding how gender influences vulnerability to these conditions is significant...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28579490/habituation-is-altered-in-neuropsychiatric-disorders-a-comprehensive-review-with-recommendations-for-experimental-design-and-analysis
#13
REVIEW
Troy A McDiarmid, Aram C Bernardos, Catharine H Rankin
Abnormalities in the simplest form of learning, habituation, have been reported in a variety of neuropsychiatric disorders as etiologically diverse as Autism Spectrum Disorder, Fragile X syndrome, Schizophrenia, Parkinson's Disease, Huntington's Disease, Attention Deficit Hyperactivity Disorder, Tourette's Syndrome, and Migraine. Here we provide the first comprehensive review of what is known about alterations in this form of non-associative learning in each disorder. Across several disorders, abnormal habituation is predictive of symptom severity, highlighting the clinical significance of habituation and its importance to normal cognitive function...
June 1, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28577612/partnerships-with-primary-care-for-the-treatment-of-preschoolers
#14
REVIEW
Sheila M Marcus, Nasuh M Malas, Joanna M Quigley, Katherine L Rosenblum, Maria Muzik, Dayna J LePlatte-Ogini, Paresh D Patel
This article reviews mental health access issues relevant to preschool children and data on this population obtained through the Michigan Child Collaborative Care Program (MC3). The MC3 program provides telephonic consultation to primary care physicians (PCPs) in 40 counties in Michigan and video telepsychiatric consultation to patients and families. Attention-deficit/hyperactivity disorder and disruptive behavioral disorders are frequent initial presenting diagnoses, but autism spectrum disorders, parent-child relational issues, trauma, and posttraumatic stress disorder should also be considered...
July 2017: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28568910/sex-differences-in-parent-reported-executive-functioning-and-adaptive-behavior-in-children-and-young-adults-with-autism-spectrum-disorder
#15
Emily I White, Gregory L Wallace, Julia Bascom, Anna C Armour, Kelly Register-Brown, Haroon S Popal, Allison B Ratto, Alex Martin, Lauren Kenworthy
This study is the largest to date examining executive function and adaptive skills in females with autism spectrum disorder (ASD). Its primary aim was to utilize parent ratings of real-world executive functioning and adaptive behavior to better understand whether females with ASD differ from males with ASD in these areas of everyday functioning. We compared 79 females with ASD to 158 males with ASD (ages 7-18) who were statistically matched on age, IQ, and level of ADHD or ASD traits. All participants were assessed using the Behavior Rating Inventory of Executive Function (BRIEF) and a subset (56 females and 130 males) also received the Vineland Adaptive Behavior Scales (VABS)...
June 1, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28567415/neurodevelopmental-disorders-and-environmental-toxicants-epigenetics-as-an-underlying-mechanism
#16
REVIEW
Nguyen Quoc Vuong Tran, Kunio Miyake
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research into the identification of etiologic and risk factors. The Developmental Origin of Health and Disease (DOHaD) hypothesizes that the environment during fetal and childhood development affects the risk for many chronic diseases in later stages of life, including neurodevelopmental disorders. Epigenetics, a term describing mechanisms that cause changes in the chromosome state without affecting DNA sequences, is suggested to be the underlying mechanism, according to the DOHaD hypothesis...
2017: International Journal of Genomics
https://www.readbyqxmd.com/read/28562247/neurodevelopment-the-impact-of-nutrition-and-inflammation-during-preconception-and-pregnancy-in-low-resource-settings
#17
Betty R Vohr, Elysia Poggi Davis, Christine A Wanke, Nancy F Krebs
The rapid pace of fetal development by far exceeds any other stage of the life span, and thus, environmental influences can profoundly alter the developmental course. Stress during the prenatal period, including malnutrition and inflammation, impact maternal and fetal neurodevelopment with long-term consequences for physical and mental health of both the mother and her child. One primary consequence of maternal malnutrition, inflammation, and other sources of prenatal stress is a poor birth outcome, such as prematurity or growth restriction...
April 2017: Pediatrics
https://www.readbyqxmd.com/read/28555406/investigation-of-previously-implicated-genetic-variants-in-chronic-tic-disorders-a-transmission-disequilibrium-test-approach
#18
Mohamed Abdulkadir, Douglas Londono, Derek Gordon, Thomas V Fernandez, Lawrence W Brown, Keun-Ah Cheon, Barbara J Coffey, Lonneke Elzerman, Carolin Fremer, Odette Fründt, Blanca Garcia-Delgar, Donald L Gilbert, Dorothy E Grice, Tammy Hedderly, Isobel Heyman, Hyun Ju Hong, Chaim Huyser, Laura Ibanez-Gomez, Ewgeni Jakubovski, Young Key Kim, Young Shin Kim, Yun-Joo Koh, Sodahm Kook, Samuel Kuperman, Bennett Leventhal, Andrea G Ludolph, Marcos Madruga-Garrido, Athanasios Maras, Pablo Mir, Astrid Morer, Kirsten Müller-Vahl, Alexander Münchau, Tara L Murphy, Kerstin J Plessen, Veit Roessner, Eun-Young Shin, Dong-Ho Song, Jungeun Song, Jennifer Tübing, Els van den Ban, Frank Visscher, Sina Wanderer, Martin Woods, Samuel H Zinner, Robert A King, Jay A Tischfield, Gary A Heiman, Pieter J Hoekstra, Andrea Dietrich
Genetic studies in Tourette syndrome (TS) are characterized by scattered and poorly replicated findings. We aimed to replicate findings from candidate gene and genome-wide association studies (GWAS). Our cohort included 465 probands with chronic tic disorder (93% TS) and both parents from 412 families (some probands were siblings). We assessed 75 single nucleotide polymorphisms (SNPs) in 465 parent-child trios; 117 additional SNPs in 211 trios; and 4 additional SNPs in 254 trios. We performed SNP and gene-based transmission disequilibrium tests and compared nominally significant SNP results with those from a large independent case-control cohort...
May 29, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28548194/-heritability-and-genetic-comorbidity-of-attention-deficit-disorder-with-hyperactivity
#19
Giannina Puddu, Paula Rothhammer, Ximena Carrasco, Francisco Aboitiz, Francisco Rothhammer
This review aims to summarize information about the genetic etiology of attention deficit disorder with hyperactivity (ADHD), with particular reference to the contributions of our research group. We also discuss the genetic comorbidity estimated from genome-wide single nucleotide polymorphisms (SNP´s) between ADHD and major psychiatric disorders such as schizophrenia (E), major depressive disorder (MDD), bipolar disorder (BD) and autism spectrum disorders (ASD). A high genetic comorbidity was found between E and BD (46%), a moderate comorbidity between MDD and E, MDD and BD and MDD and ADHD (18%, 22% and 10% respectively) and a low comorbidity between E and ASD (2...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28546058/the-role-of-il-6-in-neurodevelopment-after-prenatal-stress
#20
Serena B Gumusoglu, Rebecca S Fine, Samuel J Murray, Jada L Bittle, Hanna E Stevens
Prenatal stress exposure is associated with adverse psychiatric outcomes, including autism and ADHD, as well as locomotor and social inhibition and anxiety-like behaviors in animal offspring. Similarly, maternal immune activation also contributes to psychiatric risk and aberrant offspring behavior. The mechanisms underlying these outcomes are not clear. Offspring microglia and the pro-inflammatory cytokine interleukin-6 (IL-6), known to influence microglia, may serve as common mechanisms between prenatal stress and prenatal immune activation...
May 22, 2017: Brain, Behavior, and Immunity
keyword
keyword
61477
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"