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https://www.readbyqxmd.com/read/28214491/relationship-between-patient-reported-symptoms-limitations-in-daily-activities-and-psychological-impact-in-varicose-veins
#1
Rajiv Mallick, Brajesh Kumar Lal, Claire Daugherty
OBJECTIVE: The objective of this study was to evaluate the relationship between patient-reported symptoms, functional limitations, and psychological impact of varicose veins (VVs) vs pathophysiologic mechanism, incorporating demographic and behavioral factors. METHODS: We conducted a pooled analysis from two clinical studies (Efficacy and Safety Study of Polidocanol Injectable Foam for the Treatment of Saphenofemoral Junction Incompetence [VANISH-1] and Polidocanol Endovenous Microfoam Versus Vehicle for the Treatment of Saphenofemoral Junction Incompetence [VANISH-2]) in patients with VVs (superficial venous reflux only)...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214490/saphenous-vein-wall-thickness-in-age-and-venous-reflux-associated-remodeling-in-adults
#2
Nicos Labropoulos, Kelli Leilani Summers, Ignacio Escotto Sanchez, Joseph Raffetto
OBJECTIVE: This prospective study was designed to determine the great saphenous vein (GSV) wall thickness in age-related and venous reflux-associated remodeling. METHODS: GSV wall thickness was measured in the thigh and calf using a duplex ultrasound 17-MHz transducer. Interobserver and intraobserver variability studies were performed. Two healthy control groups, each with 10 individuals (20 limbs), were selected on the basis of age. Group 1 had a mean age of 21 years, and group 2 had a mean age of 64 years...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214489/ablation-of-the-great-saphenous-vein-with-nontumescent-n-butyl-cyanoacrylate-versus-endovenous-laser-therapy
#3
İsmail Koramaz, Helin El Kılıç, Fatih Gökalp, Macit Bitargil, Nilüfer Bektaş, Ersoy Engin, Mehmet Taşkın Egici, Ahmet Kürşat Bozkurt
OBJECTIVE: The endovenous application of n-butyl cyanoacrylate (NBCA) is a new nontumescent ablation technique for the treatment of venous insufficiency. The aim of this study was to retrospectively compare an NBCA-based ablation method with endovenous laser ablation (EVLA) for the management of incompetent great saphenous veins. METHODS: Between May 2013 and August 2014, there were 339 patients with incompetent varicose veins who were treated with either the endovenous application of NBCA (VariClose Vein Sealing System [VVSS]; Biolas, Ankara, Turkey) or EVLA...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214487/radiofrequency-ablation-with-concomitant-stab-phlebectomy-increases-risk-of-endovenous-heat-induced-thrombosis
#4
Caitlin W Hicks, Sandra R DiBrito, J Trent Magruder, M Libby Weaver, Cathy Barenski, Jennifer A Heller
OBJECTIVE: Endovenous heat-induced thrombosis (EHIT) is a well-documented phenomenon that follows endovenous ablation, but the treatment, surveillance, and risk factors for EHIT have yet to be comprehensively elucidated. We sought to identify characteristics that may put patients at higher risk for development of EHIT after radiofrequency ablation (RFA) for the treatment of symptomatic superficial venous insufficiency. METHODS: A retrospective review was performed of all consecutive patients undergoing treatment with RFA to the great saphenous vein by a single surgeon from July 2013 through October 2015...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28203474/unexpected-radiation-induced-aortic-wall-thickening-requiring-composite-graft-technique-during-off-pump-coronary-artery-bypass-grafting
#5
Paola Redaelli, Amando Gamba, Antonello Stefano Martino, Michele Triggiani
Mediastinal radiation is commonly used to treat Hodgkin's and non-Hodgkin's lymphoma, lung and breast cancer. Cardiac complications after radiation therapy are well described, although rare. A large spectrum of injuries can occur, causing long term morbidity among survivors. We describe a case of post-actinic ascending aortic wall thickening that prevented saphenous vein proximal anastomosis and was successfully managed with aortic no-touch off-pump coronary artery bypass grafting (OPCAB), 25 years after radiation therapy for Hodgkin's lymphoma...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28198595/free-microvascular-rotationplasty-with-nerve-repair-for-rhabdomyosarcoma-in-a-18-month-old-patient
#6
Alberto Pérez-García, Marta Salom, María Eloísa Villaverde-Doménech, Francisco Baixauli, Eduardo Simón-Sanz
Rotationplasty is a limb-sparing surgical option in lower limb malignancies. Sciatic or tibial nerve encasement has been considered an absolute contraindication to this procedure. We report a case of an 18-month-old girl with a rhabdomyosarcoma that affected the leg and popliteal fossa, with neurovascular involvement. Knee and proximal leg intercalary resection was performed followed by reconstruction with free microvascular rotationplasty and neurorraphy from tibial division of sciatic nerve to sural and tibial nerves, and from saphenous nerve to superficial peroneal nerve...
February 15, 2017: Microsurgery
https://www.readbyqxmd.com/read/28195033/techniques-for-nonterminal-blood-sampling-in-black-tailed-prairie-dogs-cynomys-ludovicianus
#7
Valerie Head David Eshar And Melissa R Nau
Black-tailed prairie dogs (Cynomys ludovicianus) are used as an animal model for research on gallbladder stones and several infectious diseases. A comprehensive, instructive resource regarding the appropriate techniques for venipuncture and collection of nonterminal blood samples in this species has not yet been published. Blood samples (1 mL or larger) were readily obtained from the jugular vein, femoral vein, or cranial vena cava, whereas peripheral sites, such as the cephalic vein, saphenous vein, and tarsal vein, mainly were useful for obtaining smaller volumes...
February 13, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28194628/association-between-ck-mb-area-under-the-curve-and-tranexamic-acid-utilization-in-patients-undergoing-coronary-artery-bypass-surgery
#8
Sean van Diepen, Peter D Merrill, Michel Carrier, Jean-Claude Tardif, Mihai Podgoreanu, John H Alexander, Renato D Lopes
Myonecrosis after coronary artery bypass graft (CABG) surgery is associated with excess mortality. Tranexamic acid (TA), an anti-fibrinolytic agent, has been shown to reduce peri-operative blood loss without increasing the risk of myocardial infarction (MI); however, no large study has examined the association between TA treatment and post-CABG myonecrosis. In the MC-1 to Eliminate Necrosis and Damage in Coronary Artery Bypass Graft Surgery II trial, inverse probability weighting of the propensity to receive TA was used to test for differences among the 656 patients receiving and 770 patients not receiving TA...
February 14, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28190463/prophylactic-topical-paeoniflorin-prevents-mechanical-allodynia-caused-by-paclitaxel-in-mice-through-adenosine-a1-receptors
#9
Tsugunobu Andoh, Nao Kobayashi, Daisuke Uta, Yasushi Kuraishi
BACKGROUND: The chemotherapeutic agent paclitaxel (PTX) causes refractory peripheral neuropathy as a side effect. Prophylactic oral administration of the traditional herbal medicine Shakuyakukanzoto containing Paeoniae Radix and Glycyrrhizae Radix prevents the development of PTX-induced mechanical allodynia in mice via peripheral effects, mostly due to Paeoniae Radix. However, the bioactive component responsible for the prevention of PTX-induced neuropathic pain remains unknown. PURPOSE: To determine whether a monoterpene glycoside paeoniflorin (PF), which is the principal bioactive constituent of Paeoniae Radix, has inhibitory effects on PTX-induced mechanical allodynia and investigate the underlying mechanisms...
February 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28186621/the-importance-of-great-saphenous-vein-types-and-segmental-aplasia-in-venous-reflux
#10
Elif Evrim Ekin, Hülya Kurtul Yildiz
PURPOSE: To investigate the relationship among great saphenous vein (GSV) anatomic type, segmental aplasia, and reflux. METHODS: Color Doppler ultrasonography (CDUS) was performed on 475 legs of 277 consecutive patients with venous symptoms between November 2015 and August 2016. Exclusion criteria were previous venous surgery and venous thrombosis. Five GSV types were identified based on the saphenous compartment at thigh level, and segment aplasia and reflux were investigated...
February 10, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28186424/defining-local-nerve-blocks-for-feline-distal-pelvic-limb-surgery-a-cadaveric-study
#11
Masataka Enomoto, B Duncan X Lascelles, Mathew P Gerard
Objectives Anatomical and methodological detail is lacking regarding local anesthetic peripheral nerve block techniques for distal pelvic limb surgery in cats. The aim of this study was to develop, describe and test nerve block methods based on cadaveric dissections and dye injections. Methods Ten pairs of feline pelvic limbs (n = 20) were dissected and the tibial nerve (T n.), common fibular (peroneal) nerve (CF n., and its two branches, the superficial fibular [peroneal] nerve [SpF n.] and the deep fibular [peroneal] nerve [DpF n...
February 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28185533/mapping-the-methylation-status-of-the-mir-145-promoter-in-saphenous-vein-smooth-muscle-cells-from-individuals-with-type-2-diabetes
#12
Kirsten Riches, John Huntriss, Claire Keeble, Ian C Wood, David J O'Regan, Neil A Turner, Karen E Porter
Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 diabetes mellitus-smooth muscle cell phenotype driven by persistent up-regulation of miR-145. This study aimed to determine whether elevated expression was due to changes in methylation at the miR-145 promoter. Smooth muscle cells were cultured from saphenous veins of 22 non-diabetic and 22 type 2 diabetes mellitus donors...
March 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28185396/primary-percutaneous-coronary-intervention-of-native-chronic-total-occlusions-to-treat-st-elevation-myocardial-infarction-secondary-to-acute-vein-graft-occlusion
#13
Pierre Deharo, Julian W Strange, Abdul Mozid
Primary percutaneous coronary intervention (PCI) is the treatment modality of choice in patients presenting with ST elevation myocardial infarction (STEMI). Clinical outcomes have dramatically improved with the wide adoption of primary PCI in patients with STEMI because of acute thrombotic native coronary artery occlusion. However, patients with prior coronary artery bypass graft (CABG) surgery who present with STEMI because of acute saphenous vein graft (SVG) occlusion continue to have worse outcomes because of poor acute and long-term results of SVG stenting...
February 10, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28181086/bilateral-cavernous-carotid-aneurysms-treated-by-two-stage-extracranial-intracranial-bypass-followed-by-parent-artery-occlusion-case-report-and-literature-review
#14
Yaoling Liu, Xiang'en Shi, Fangjun Liu, Yuming Sun, Hai Qian, Ting Lei
Bilateral cavernous carotid aneurysms (CCAs) are often not amenable to neurosurgical clipping or endovascular coiling. Here, we report the case of a 50-year-old female who presented with a 1-year history of gradual severe headache. Preoperative angiograms revealed bilateral CCAs. Among these findings, the right giant CCA had been trapped after the external carotid artery-saphenous vein-middle cerebral artery (ECA-SV-MCA) bypass 8 years prior. Additionally, the left CCA was again trapped after the internal maxillary artery-radial artery-middle cerebral artery (IMA-RA-MCA) bypass, followed by parent artery occlusion (PAO), because of the enlargement of a 0...
February 8, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28171798/distribution-of-bupivacaine-hydrochloride-after-sciatic-and-femoral-nerve-blocks-in-cats-a-magnetic-resonance-imaging-study
#15
Marina C Evangelista, Julie de Lassalle, Christine Chevrier, Eric N Carmel, Denise T Fantoni, Paulo V M Steagall
The objective of this study was to evaluate the distribution of bupivacaine hydrochloride using magnetic resonance imaging (MRI) after electrical nerve stimulator (ENS)-guided sciatic (ScN) and femoral (FN) nerve blocks in cats. Six adult cats (body weight 4.8±0.6kg) were anesthetized with acepromazine-buprenorphine-propofol-isoflurane. Transverse and sagittal plan sequences of pelvic limbs were obtained using a high-field magnet (1.5T). Afterwards, the ScN and FN blocks (one block per limb) were performed using 0...
January 27, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28166379/reference-values-for-rotational-thromboelastometry-rotem-in-clinically-healthy-cats
#16
Charlotte Marly-Voquer, Barbara Riond, Rahel Jud Schefer, Annette P N Kutter
OBJECTIVE: To establish reference intervals for rotational thromboelastometry (ROTEM) using feline blood. DESIGN: Prospective study. SETTING: University teaching hospital. ANIMALS: Twenty-three clinically healthy cats between 1 and 15 years. INTERVENTION: For each cat, whole blood was collected via jugular or medial saphenous venipuncture, and blood was placed into a serum tube, a tube containing potassium-EDTA, and tubes containing 3...
February 6, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28163174/arterial-blood-pressure-induces-transient-c4b-binding-protein-in-human-saphenous-vein-grafts
#17
Koba Kupreishvili, Christof Meischl, Alexander B A Vonk, Wim Stooker, Leon Eijsman, Anna M Blom, Paul H A Quax, Victor W M van Hinsbergh, Hans W M Niessen, Paul A J Krijnen
BACKGROUND: Complement is an important mediator in arterial blood pressure-induced vein graft failure. Previously we noted activation of cell protective mechanisms in human saphenous veins too. Here we have analyzed whether C4b-binding protein (C4bp), an endogenous complement inhibitor, is present in the vein wall. MATERIALS AND METHODS: Human saphenous vein segments obtained from patients undergoing coronary artery bypass grafting (n=55) were perfused in vitro at arterial blood pressure with either autologous blood for 1, 2, 4 or 6 hours or with autologous blood supplemented with reactive oxygen species scavenger N-acetylcysteine...
February 2, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28161564/management-of-vascular-trauma-during-the-paris-terrorist-attack-of-november-13-2015
#18
Philippe Tresson, Joseph Touma, Julien Gaudric, Quentin Pellenc, Marielle Le Roux, Charles Pierret, Hicham Kobeiter, Pierre Julia, Olivier Goeau-Brissonniere, Pascal Desgranges, Fabien Koskas, Yves Castier
OBJECTIVES: On November 13, 2015, Paris and Saint-Denis were the targets of terrorist attacks. The hospitals of the Public Hospitals of Paris Organization (AP-HP) and the Percy Armed Forces Instruction Hospitals were mobilized to face the mass casualty situation. The objective of this study was to analyze the management of the victims presenting with a non-thoracic vascular trauma (NTVT). MATERIAL AND METHODS: All the data relating to the victims of NTVT who required a specific vascular open or endovascular treatment were analyzed retrospectively...
February 1, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28160323/recipient-vessels-for-microsurgical-flaps-to-the-abdomen-a-systematic-review
#19
REVIEW
Raffi Gurunluoglu, Michael J Rosen
BACKGROUND: Large soft tissue defects of the abdominal wall resulting from various reasons may require free tissue transfer. METHODS: A literature search of PubMed and Cochrane electronic databases was conducted to identify articles involving abdominal wall reconstruction (AWR) with microsurgical flap. Number of cases, etiology, and reconstruction site, type of microsurgical flap and recipient vessels were analyzed. RESULTS: Thirty-eight articles published between 1983 and 2016 reported on 149 patients undergoing free flap AWR...
February 4, 2017: Microsurgery
https://www.readbyqxmd.com/read/28151029/radiofrequency-induced-thermotherapy-rfitt-in-a-porcine-liver-model-and-ex-vivo-great-saphenous-vein
#20
George E Badham, Scott J Dos Santos, Mark S Whiteley
AIMS: To investigate the thermal spread achieved in porcine liver when using an optimised radiofrequency ablation protocol and correlate findings with the effects seen in ex vivo great saphenous vein (GSV), in order to justify clinical use with the new treatment protocol. MATERIAL AND METHODS: Porcine liver and GSV sections were treated with radiofrequency-induced thermotherapy (RFiTT) using the following settings: 20 W at 1 s/cm (linear endovenous energy density; LEED 20 J/cm), 18 W at 1 s/cm (LEED 18 J/cm), 18 W at 3 s/cm (LEED 54 J/cm), 6 W interrupted pull-back 6 s stationary every 0...
February 2, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
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