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JOURNAL ARTICLE
Brett N Bentkowski, Koral M Blunt, Eric M Milliron, Parker A Cavendish, Ryan H Barnes, Christopher C Kaeding, Robert A Magnussen, Paul Stoodley, David C Flanigan
BACKGROUND: Approximately 100,000 anterior cruciate ligament (ACL) reconstructions (ACLRs) occur annually in the United States, and postoperative surgical-site infection is a relatively rare but devastating complication, often leading to graft failure or septic arthritis of the knee, necessitating repeat surgery. Wrapping allografts in vancomycin-soaked gauze has been adopted as a common sterilization technique in the operating room to reduce surgical-site infection; however, identifying effective alternatives to vancomycin has not been extensively pursued...
February 2, 2024: American Journal of Sports Medicine
#2
JOURNAL ARTICLE
Yvonne Hao, Jorge Trilles, Hilliard T Brydges, Daniel Boczar, Keerthi K Kurian, Bachar F Chaya, Ricardo Rodriguez Colon, Augustus Parker, Paul E Kwak, Eduardo D Rodriguez
OBJECTIVES: For transwomen undergoing voice feminization interventions, fundamental frequency (F 0 ; vocal pitch) is a commonly reported functional outcome measure in the literature. However, F 0 may not correlate well with improvement in quality of life (QoL). Several validated voice-related QoL instruments have been used to assess QoL improvement in these patients, yet there is no consensus on the most appropriate instrument. This systematic review and meta-analysis aimed to assess the relationship between change in F 0 and QoL improvement following voice feminization, and to compare validated QoL instruments commonly used in this population...
September 13, 2023: Journal of Craniofacial Surgery
#3
JOURNAL ARTICLE
Joseph Dynako, Martin McCandless, Richard Covington, Paul Williams, Michael Robertson, Parker White, Joshua Milby, John Morellato
PURPOSE: To determine the timing of symptomatic venous thromboemboli (VTE) in patients sustaining a pelvic and/or acetabular fracture. Secondly, to evaluate for any factors that may influence this timing. METHODS: A retrospective cohort of 47 patients with acetabular and/or pelvic ring injuries who developed VTEs at a single academic level I trauma center were identified from 2012 to 2018. The chronology of VTE diagnosis in relation to date of injury, initial surgery, final surgery, and date of discharge was evaluated...
July 19, 2023: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
#4
JOURNAL ARTICLE
Koral M Blunt, Brett N Bentkowski, Eric Milliron, Parker Cavendish, Charles Qin, Robert A Magnussen, Paul Stoodley, David C Flanigan
BACKGROUND: Postoperative infections, commonly from Staphylococcus epidermidis , may result in anterior cruciate ligament graft failure and necessitate revision surgery. In biomechanical studies, S. epidermidis has been shown to establish biofilms on tendons and reduce graft strength. PURPOSE/HYPOTHESIS: The goal of this study was to determine the effect of bacterial bioburden on the collagen structure of tendon. It was hypothesized that an increase in S. epidermidis biofilm would compromise tendon crimp, a pattern necessary for mechanical integrity, of soft tissue allografts...
July 14, 2023: American Journal of Sports Medicine
#5
JOURNAL ARTICLE
Arya Ahmady, Lindsay Rosenthal, Adam C Abraham, Bianca Parker, Jaysson T Brooks, Patrick J Cahill, John T Smith, Paul D Sponseller, Peter F Sturm, Ying Li
BACKGROUND: Lower preoperative pelvic obliquity (PO) and L5 tilt have been associated with good radiographic outcomes when the fusion ended short of the pelvis in children with neuromuscular scoliosis (NMS). Our purpose was to identify indications to exclude the pelvis in children with hypotonic NMS treated with growth-friendly instrumentation. METHODS: This was a multicenter retrospective review. Children with spinal muscular atrophy and muscular dystrophy treated with dual traditional growing rod, magnetically controlled growing rod, or vertical expandable prosthetic titanium rib with minimum 2-year follow-up after the index surgery were identified...
February 27, 2023: Journal of Pediatric Orthopedics
#6
JOURNAL ARTICLE
Nehal Ninad, Macie Edwards, Paul Parker, Joshua Glenn
Lack of peritoneal violation has been a strong tenet of nonoperative management for extraperitoneal penetrating injuries. There have been reports of intraperitoneal injuries without peritoneal violation in adult trauma literature. Such reports are scarce in pediatric trauma. We report delayed presentation of a small bowel injury in a 4-year-old male following extraperitoneal ballistic injury. No peritoneal violation was noted on wound exploration allowing conservative management. Patient developed abdominal distention on postoperative day 1, and radiologic imaging showed intraperitoneal air warranting an exploratory laparotomy...
September 2023: American Surgeon
#7
REVIEW
Ahmad A Aref, Paul R Parker, Michael Y Chen
PURPOSE OF REVIEW: To critically summarize and examine published data from randomized controlled clinical trials (RCTs) investigating the safety and efficacy of microinvasive glaucoma surgeries (MIGS) with and without cataract surgery versus cataract surgery alone. RECENT FINDINGS: Three RCTs with standardized outcomes and rigorous methodology demonstrate superiority of the iStent (Glaukos), CyPass (Alcon), and Hydrus (Alcon) MIGS devices in combination with cataract surgery versus cataract surgery alone...
March 1, 2023: Current Opinion in Ophthalmology
#8
JOURNAL ARTICLE
Jennifer M Byrd, Ceylan Colak, Sercan Yalcin, Carl Winalski, Isaac Briskin, Lutul D Farrow, Morgan H Jones, Anthony A Miniaci, Richard D Parker, James T Rosneck, Paul M Saluan, Gregory J Strnad, Kurt P Spindler
Background: Bone bruise patterns after anterior cruciate ligament (ACL) rupture may predict the presence of intra-articular pathology and help explain the mechanism of injury. Lateral femoral condyle (LFC) and lateral tibial plateau (LTP) bone bruises are pathognomic to ACL rupture. There is a lack of information regarding medial tibial plateau (MTP) and medial femoral condyle (MFC) bone bruises. Purpose: To summarize the prevalence and location of MTP bone bruises with acute ACL rupture and to determine the predictors of MTP bone bruises...
October 2022: Orthopaedic Journal of Sports Medicine
#9
JOURNAL ARTICLE
Jordan V Wang, Paul M Friedman, Samantha Agron, Adarsh Konda, Catherine Parker, Roy G Geronemus
BACKGROUND: Laser pretreatment with cosmeceutical topicals is growing in popularity. However, lasers may also enhance the uptake of medical topicals that treat dermatologic conditions, such as vitiligo, alopecia, and cancerous and precancerous lesions. Permeation of these topicals must be quantified to optimize treatment protocols. OBJECTIVE: To analyze transdermal uptake of 3 topicals after nonablative fractional 1,550-nm erbium-doped glass or 1,927-nm thulium fiber laser pretreatment...
September 1, 2022: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
#10
JOURNAL ARTICLE
Jordan V Wang, Paul M Friedman, Deirdre Rodeberg, Adarsh Konda, Catherine Parker, Roy G Geronemus
BACKGROUND: Energy-based devices, such as nonablative lasers, are a promising method to enhance the delivery and absorption of topically applied molecules. OBJECTIVE: To characterize ex vivo uptake of common antioxidant topicals after pretreatment with a nonablative laser wavelength. MATERIALS AND METHODS: Using donor human skin tissue, uptake of 3 topical antioxidants was analyzed (C E Ferulic with 15% l-ascorbic acid [15% vitamin C serum], Phloretin CF with ferulic acid [10% vitamin C serum], and Phyto+ [botanical serum]; SkinCeuticals, Dallas, TX; 2010 formulations) after pretreatment with a 1,440-nm nonablative fractional diode laser...
September 1, 2022: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
#11
JOURNAL ARTICLE
Andrew Beckett, Paul Parker, Phillip Williams, Homer Tien
IMPORTANCE: The most common cause of preventable death on the conventional battlefield or on special operations force (SOF) missions is hemorrhage. SOF missions may take place in remote and austere locations. Many preventable deaths in combat occur within 30 min of wounding. Therefore, SOF damage control resuscitation (DCR) and damage control surgery (DCS) teams may improve combat casualty survival in the SOF environment. OBJECTIVE: To determine the effect of SOF DCR and DCS teams on combat casualty survival...
June 29, 2022: Transfusion
#12
JOURNAL ARTICLE
Jordan V Wang, Paul M Friedman, Samantha Agron, Adarsh Konda, Catherine Parker, Roy G Geronemus
BACKGROUND: Although the stratum corneum limits transdermal absorption of topicals, laser devices can enhance topical uptake by disrupting the skin barrier. Nonablative lasers are commonly used, but their effects on topical uptake should be quantified to optimize outcomes. OBJECTIVE: The objective of this study is to analyze transdermal uptake of 4 topicals after nonablative fractional diode laser pretreatment. METHODS AND MATERIALS: Human donor tissue was pretreated ex vivo with a nonablative fractional diode laser (1,927 nm or 1,440 nm, at varying treatment densities, powers, and peak energies) followed by application of either 2% salicylic acid, 10% ascorbic acid, over-the-counter mineral eye serum, or 4% hydroquinone...
August 1, 2022: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
#13
JOURNAL ARTICLE
Mary R Shen, Lucy Zhuo, Kerry Madison, Brooke C Bredbeck, Michael T Kemp, Jessica R Santos-Parker, Gurjit Sandhu, Brian C George, Paul G Gauger, David T Hughes, Justin B Dimick, Gifty Kwakye
OBJECTIVE: The taxing nature of surgery residency is well-documented in the literature, with residents demonstrating high rates of burnout, depression, suicidal thoughts, sexual harassment, and racial discrimination. Mentoring has been shown to improve camaraderie, address challenges of underrepresentation in medicine, and be associated with lower burnout. However, existing formal mentoring programs tend to be career-focused and hierarchal without opportunity to discuss important sociocultural issues...
September 2022: Journal of Surgical Education
#14
MULTICENTER STUDY
John R Bergquist, Omair A Shariq, Amy Y Li, Patrick J Worth, Nikolaos Chatzizacharias, Zahir Soonawalla, Panagiotis Athanasopoulos, Christos Toumpanakis, Paul Hansen, Rowan W Parks, Saxon Connor, Kate Parker, Jonathan Koea, Sanket Srinivasa, Benedetto Ielpo, Emilio Vicente Lopez, Jeffrey A Norton, Ben Lawrence, Brendan C Visser
BACKGROUND: The optimal surgical management of pancreatic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1 is controversial. This study sought to compare clinicopathologic characteristics and outcomes of multiple endocrine neoplasia type 1-associated and sporadic pancreatic neuroendocrine tumors from a large multi-national database. METHODS: A multi-institutional, international database of patients with surgically resected pancreatic neuroendocrine tumors was analyzed...
August 2022: Surgery
#15
RANDOMIZED CONTROLLED TRIAL
David A Palma, Eitan Prisman, Eric Berthelet, Eric Tran, Sarah Hamilton, Jonn Wu, Antoine Eskander, Kevin Higgins, Irene Karam, Ian Poon, Zain Husain, Danny Enepekides, Michael Hier, Khalil Sultanem, Keith Richardson, Alex Mlynarek, Stephanie Johnson-Obaseki, Michael Odell, Andrew Bayley, Samuel Dowthwaite, James E Jackson, Marcin Dzienis, John O'Neil, Shamir Chandarana, Robyn Banerjee, Robert Hart, Jeffson Chung, Todd Tenenholtz, Suren Krishnan, Hien Le, John Yoo, Adrian Mendez, Eric Winquist, Sara Kuruvilla, Paul Stewart, Andrew Warner, Sylvia Mitchell, Jeff Chen, Christina Parker, Bret Wehrli, Keith Kwan, Julie Theurer, Jinka Sathya, J Alex Hammond, Nancy Read, Varagur Venkatesan, S Danielle MacNeil, Kevin Fung, Anthony C Nichols
IMPORTANCE: The optimal approach for treatment deescalation in human papillomavirus (HPV)-related oropharyngeal squamous cell carcinomas (OPSCCs) is unknown. OBJECTIVE: To assess a primary radiotherapy (RT) approach vs a primary transoral surgical (TOS) approach in treatment deescalation for HPV-related OPSCC. DESIGN, SETTING, AND PARTICIPANTS: This international, multicenter, open-label parallel-group phase 2 randomized clinical trial was conducted at 9 tertiary academic cancer centers in Canada and Australia and enrolled patients with T1-T2N0-2 p16-positive OPSCC between February 13, 2018, and November 17, 2020...
June 1, 2022: JAMA Oncology
#16
EDITORIAL
Paul Parker, A M Johnston, A Mountain, H Pynn
No abstract text is available yet for this article.
January 18, 2022: BMJ military health
#17
JOURNAL ARTICLE
Marianne E Nellis, Oliver Karam, Stacey L Valentine, Scot T Bateman, Kenneth E Remy, Jacques Lacroix, Jill M Cholette, Melania M Bembea, Robert T Russell, Marie E Steiner, Susan M Goobie, Marisa Tucci, Paul A Stricker, Simon J Stanworth, Meghan Delaney, Lani Lieberman, Jennifer A Muszynski, David F Bauer, Katherine Steffen, Daniel Nishijima, Juan Ibla, Sitaram Emani, Adam M Vogel, Thorsten Haas, Ruchika Goel, Gemma Crighton, Diana Delgado, Michelle Demetres, Robert I Parker
OBJECTIVES: Critically ill children frequently receive plasma and platelet transfusions. We sought to determine evidence-based recommendations, and when evidence was insufficient, we developed expert-based consensus statements about decision-making for plasma and platelet transfusions in critically ill pediatric patients. DESIGN: Systematic review and consensus conference series involving multidisciplinary international experts in hemostasis, and plasma/platelet transfusion in critically ill infants and children (Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding [TAXI-CAB])...
January 1, 2022: Pediatric Critical Care Medicine
#18
JOURNAL ARTICLE
Marisa Tucci, Gemma Crighton, Susan M Goobie, Robert T Russell, Robert I Parker, Thorsten Haas, Marianne E Nellis, Adam M Vogel, Jacques Lacroix, Paul A Stricker
OBJECTIVES: To present consensus statements and supporting literature for plasma and platelet transfusions in critically ill children following noncardiac surgery and critically ill children undergoing invasive procedures outside the operating room from the Transfusion and Anemia EXpertise Initiative - Control/Avoidance of Bleeding. DESIGN: Systematic review and consensus conference of international, multidisciplinary experts in platelet and plasma transfusion management of critically ill children...
January 1, 2022: Pediatric Critical Care Medicine
#19
JOURNAL ARTICLE
Louis P Parker, Benedikt Reutersberg, Maaz B J Syed, Bijit Munshi, Samantha Richards, Lachlan J Kelsey, Natzi Sakalihasan, Hans-Henning Eckstein, Paul E Norman, Barry J Doyle
BACKGROUND: Improved risk stratification is a key priority for type B aortic dissection (TBAD). Partial false lumen thrombus morphology is an emerging predictor of complications however, partial thrombosis is poorly defined and its evaluation in clinical studies is inconsistent. PURPOSE: This work aims to characterise hemodynamic pressure in TBAD and determine how pressure relates to false lumen thrombus morphology and clinical events. METHODS: Retrospective admission computed tomography angiography of 69 patients with acute TBAD was used to construct three-dimensional computational models for simulation of cyclical blood flow and calculation of pressure...
November 3, 2021: Journal of Vascular Surgery
#20
JOURNAL ARTICLE
Amelia Staats, Peter W Burback, Mostafa Eltobgy, Dana M Parker, Amal O Amer, Daniel J Wozniak, Shu-Hua Wang, Kurt B Stevenson, Kenneth L Urish, Paul Stoodley
Rapid synovial fluid-induced aggregation of Staphylococcus aureus is currently being investigated as an important factor in the establishment of periprosthetic joint infections (PJIs). Pathogenic advantages of aggregate formation have been well documented in vitro , including recalcitrance to antibiotics and protection from host immune defenses. The objective of the present work was to determine the strain dependency of synovial fluid-induced aggregation by measuring the degree of aggregation of 21 clinical S...
September 15, 2021: Microbiology Spectrum
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