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https://www.readbyqxmd.com/read/29458092/ramifications-of-the-children-s-surgery-verification-program-for-patients-and-hospitals
#1
Katherine J Baxter, Bonnie F Gale, Curtis D Travers, Kurt F Heiss, Mehul V Raval
BACKGROUND: The American College of Surgeons in 2015 instituted the Children's Surgery Verification (CSV) program delineating requirements for hospitals providing pediatric surgical care. Our purpose was to examine possible effects of the CSV program by evaluating neonates undergoing high-risk operations. STUDY DESIGN: Using the Kid's Inpatient Database 2009, we identified infants undergoing surgery for five high risk neonatal conditions. We considered all children's hospitals and children's units Level I centers and considered all others Level II/III...
February 16, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29273837/diaphyseal-long-bone-nonunions-types-aetiology-economics-and-treatment-recommendations
#2
REVIEW
Markus Rupp, Christoph Biehl, Matthäus Budak, Ulrich Thormann, Christian Heiss, Volker Alt
The intention of the current article is to review the epidemiology with related socioeconomic costs, pathophysiology, and treatment options for diaphyseal long bone delayed unions and nonunions. Diaphyseal nonunions in the tibia and in the femur are estimated to occur 4.6-8% after modern intramedullary nailing of closed fractures with an even much higher risk in open fractures. There is a high socioeconomic burden for long bone nonunions mainly driven by indirect costs, such as productivity losses due to long treatment duration...
December 22, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29222935/risk-factors-for-positive-resection-margins-of-breast-cancer-tumorectomy-specimen-following-breast-conserving-surgery
#3
Niko Heiss, Valentin Rousson, Assia Ifticene-Treboux, Hans-Anton Lehr, Jean-François Delaloye
Background The aim of the study was to identify risk factors for positive surgical margins in breast-conserving surgery for breast cancer and to evaluate the influence of surgical experience in obtaining complete resection. Methods All lumpectomies for invasive breast carcinoma and ductal carcinoma in situ (DCIS) between April 2008 and March 2010 were selected from the database of a single institution. Re-excision rates for positive margins as well as patient and histopathologic tumor characteristics were analyzed...
December 9, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29199006/lb-100-a-novel-protein-phosphatase-2a-pp2a-inhibitor-sensitizes-malignant-meningioma-cells-to-the-therapeutic-effects-of-radiation
#4
Winson S C Ho, Saman Sizdahkhani, Shuyu Hao, Hua Song, Ashlee Seldomridge, Anita Tandle, Dragan Maric, Tamalee Kramp, Rongze Lu, John D Heiss, Kevin Camphausen, Mark R Gilbert, Zhengping Zhuang, Deric M Park
Atypical and anaplastic meningiomas (AAM) represent 20% of all meningiomas. They are associated with poor outcomes due to their tendency to recur. While surgery and radiation (RT) are first line therapy, no effective systemic medical treatment has been identified. Protein phosphatase 2A (PP2A) is a ubiquitously expressed serine/threonine phosphatase involved in cell cycle regulation and DNA repair. Here, we examined radiosensitizing effects of LB-100, a novel inhibitor of PP2A against AAM as a novel treatment strategy...
November 30, 2017: Cancer Letters
https://www.readbyqxmd.com/read/29076781/eccrine-spiradenoma-mimicking-a-painful-traumatic-neuroma-case-report
#5
Katelyn Donaldson, Gretchen Scott, Fredric K Cantor, Nicholas J Patronas, Martha Quezado, John D Heiss
Diagnosing and treating patients with persistent neuropathic pain associated with peripheral nerve lesions can be challenging. The authors report the rare case of a painful eccrine spiradenoma treated as a traumatic neuroma for many years because of a history of acute trauma, the presence of a tender palpable mass, and symptoms of allodynia. Surgical excision of the neoplasm completely relieved the pain and hypersensitivity that 2 prior surgeries and other nonsurgical treatments failed to resolve. The diagnosis of eccrine spiradenoma was not established until resection and histopathological analysis of the tissue...
October 27, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28655398/a-survey-of-pediatric-surgeons-practices-with-enhanced-recovery-after-children-s-surgery
#6
Heather L Short, Natalie Taylor, Mitali Thakore, Kaitlin Piper, Katherine Baxter, Kurt F Heiss, Mehul V Raval
PURPOSE: Enhanced Recovery After Surgery (ERAS) protocols have been shown to improve outcomes in adult abdominal surgical populations. Our purpose was to survey pediatric surgeons' opinions regarding applicability of individual ERAS elements to children's surgery. METHODS: A survey of the American Pediatric Surgical Association was conducted electronically. Using a 5-point Likert scale, respondents rated their willingness to implement 21 adult ERAS elements in an adolescent undergoing elective colorectal surgery...
June 17, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28545764/implementation-of-an-enhanced-recovery-protocol-in-pediatric-colorectal-surgery
#7
Heather L Short, Kurt F Heiss, Katelyn Burch, Curtis Travers, John Edney, Claudia Venable, Mehul V Raval
PURPOSE: Enhanced recovery protocols (ERPs) have been shown to improve outcomes in adult surgical populations. Our purpose was to compare outcomes before and after implementation of an ERP in children undergoing elective colorectal surgery. METHODS: A pediatric-specific colorectal ERP was developed and implemented at a single center starting in January 2015. A retrospective review was performed including 43 patients in the pre-ERP period (2012-2014) and 36 patients in the post-ERP period (2015-2016)...
May 12, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28343665/defining-the-association-between-operative-time-and-outcomes-in-children-s-surgery
#8
Heather L Short, Helene B Fevrier, Jonathan A Meisel, Matthew T Santore, Kurt F Heiss, Mark L Wulkan, Mehul V Raval
INTRODUCTION: Prolonged operative time (OT) is considered a reflection of procedural complexity and may be associated with poor outcomes. Our purpose was to explore the association between prolonged OT and complications in children's surgery. METHODS: 182,857 cases from the 2012-2014 NSQIP-Pediatric were organized into 33 groups. OT for each group was analyzed by quartile, and regression models were used to determine the relationship between prolonged OT and complications...
March 20, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28238058/training-or-non-surgical-factors-what-determines-a-good-surgical-performance-a-randomised-controlled-trial
#9
Cornelia Lindlohr, R Lefering, S Saad, M M Heiss, C Pape-Köhler
BACKGROUND: Acquiring laparoscopic skills is a necessity for every young surgeon. Whether it is a talent or a non-surgical skill that determines the surgical performance of an endoscopic operation has been discussed for years. In other disciplines aptitude testing has become the norm. Airlines, for example, have implemented assessments to test the natural aptitude of future pilots to predict their performance later on. In the medical field, especially surgery, there are no similar comparable tests implemented or even available...
June 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28162424/-199-pain-characteristics-before-and-after-chiari-1-surgery
#10
F Cantor, J Skala, J Heiss
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/27842957/clinical-validity-and-relevance-of-accidental-puncture-or-laceration-as-a-patient-safety-indicator-for-children
#11
Heather L Short, Kurt F Heiss, Mark L Wulkan, Mehul V Raval
PURPOSE: Accidental puncture or laceration (APL) has been endorsed as a patient safety indicator and is being used to compare hospital performance and for reimbursement. We sought to determine the positive predictive value (PPV) of APL as a quality metric in a pediatric population. METHODS: We retrospectively reviewed all cases that met APL administrative criteria over 5years in a quaternary pediatric hospital system. Events were categorized as false positive (FP) or true positive (TP)...
January 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27530056/the-current-status-of-immunotherapy-in-peritoneal-carcinomatosis
#12
REVIEW
Michael Alfred Ströhlein, Markus Maria Heiss, Karl-Walter Jauch
INTRODUCTION: Peritoneal carcinomatosis (PC) is a cancer disease with an urgent need for effective treatment. Conventional chemotherapy failed to show acceptable results. Cytoreductive surgery and hyperthermic chemoperfusion (HIPEC) are only beneficial in few patients with resectable peritoneal metastasis. Immunotherapy could be attractive against PC, as all requirements for immunotherapy are available in the peritoneal cavity. AREAS COVERED: This review analyzes the present literature for immunotherapy of PC...
October 2016: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/27177741/-minor-foot-amputations-in-diabetic-foot-syndrome
#13
C Biehl, M Eckhard, G Szalay, C Heiss
OBJECTIVE: The treatment strategy for diabetic foot syndrome must take into account protective sensibility of the foot, open wounds, infection status, and the rules of septic bone surgery. Interventions are classified as elective, prophylactic, curative, or emergency. Amputations in the forefoot and midfoot region are performed as ray amputations (including metatarsal), which can often be carried out as "inner" amputations. Gentle tissue treatment mandatory because of greater risk of revision with re-amputation compared to classical amputation...
October 2016: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/27083963/enhancing-recovery-in-pediatric-surgery-a-review-of-the-literature
#14
REVIEW
Julia K Shinnick, Heather L Short, Kurt F Heiss, Matthew T Santore, Martin L Blakely, Mehul V Raval
BACKGROUND: Enhanced recovery after surgery (ERAS), guidelines entail a strategy of perioperative management proven to hasten postoperative recovery and reduce complications in adult populations. Relatively few studies have investigated the applicability of this paradigm to pediatric populations. Our objective was to perform a systematic review of existing evidence regarding the use and efficacy of enhanced recovery protocols (ERPs) in the pediatric population. MATERIALS AND METHODS: Data were collected through a PubMed/MEDLINE literature search...
May 1, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27079966/emergency-department-visits-and-readmissions-among-children-after-gastrostomy-tube-placement
#15
Adam B Goldin, Kurt F Heiss, Matt Hall, David H Rothstein, Peter C Minneci, Martin L Blakely, Marybeth Browne, Mehul V Raval, Samir S Shah, Shawn J Rangel, Charles L Snyder, Charles D Vinocur, Loren Berman, Jennifer N Cooper, Marjorie J Arca
OBJECTIVES: To define the incidence of 30-day postdischarge emergency department (ED) visits and hospital readmissions following pediatric gastrostomy tube (GT) placement across all procedural services (Surgery, Interventional-Radiology, Gastroenterology) in 38 freestanding Children's Hospitals. STUDY DESIGN: This retrospective cohort study evaluated patients <18 years of age discharged between 2010 and 2012 after GT placement. Factors significantly associated with ED revisits and hospital readmissions within 30 days of hospital discharge were identified using multivariable logistic regression...
July 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27058950/analysis-of-the-first-217-appendectomies-of-the-german-notes-registry
#16
MULTICENTER STUDY
Dirk R Bulian, Georg Kaehler, Richard Magdeburg, Michael Butters, Jens Burghardt, Roland Albrecht, Joern Bernhardt, Markus M Heiss, Heinz J Buhr, Kai S Lehmann
OBJECTIVE: To analyze the feasibility and safety of Natural Orifice Transluminal Endoscopic Surgery (NOTES) appendectomy, and to analyze separately the transvaginal appendectomy (TVAE) and the transgastric appendectomy (TGAE) procedures. BACKGROUND: Laparoscopic appendectomy has rare but relevant complications, namely incisional hernias and neuralgia at the trocar sites, which can potentially be avoided by the NOTES techniques. METHODS: The first 217 data sets of the largest NOTES registry worldwide-the German NOTES registry-were analyzed with respect to demographic data, procedural data, and short-term outcomes...
March 2017: Annals of Surgery
https://www.readbyqxmd.com/read/26681348/the-omega-jejunostomy-tube-a-preferred-alternative-for-postpyloric-feeding-access
#17
Avraham Schlager, Kelly Arps, Ragavan Siddharthan, Priya Rajdev, Kurt F Heiss
AIM: We present our technique for construction of the "Omega Jejunostomy" (OJ), a novel method of postpyloric feeding using a pouched-jejunal loop capable of accommodating a balloon gastrostomy button. We describe potential indications for the procedure and outcomes in a complex patient population. MATERIALS AND METHODS: We retrospectively reviewed records of patients who underwent an OJ at our institution between 2005 and 2014. Primary outcomes include operating time, length of hospital stay, time to feeding goals, and postoperative complications...
February 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/26408057/pathogenesis-and-cerebrospinal-fluid-hydrodynamics-of-the-chiari-i-malformation
#18
REVIEW
Thomas J Buell, John D Heiss, Edward H Oldfield
This article summarizes the current understanding of the pathophysiology of the Chiari I malformation that is based on observations of the anatomy visualized by modern imaging with MRI and prospective studies of the physiology of patients before and after surgery. The pathogenesis of a Chiari I malformation of the cerebellar tonsils is grouped into 4 general mechanisms.
October 2015: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/26374949/effects-of-recombinant-human-bone-morphogenetic-protein-2-rhbmp-2-in-grade-iii-open-tibia-fractures-treated-with-unreamed-nails-a-clinical-and-health-economic-analysis
#19
Volker Alt, Benny Borgman, Alexander Eicher, Christian Heiss, Nikolaos K Kanakaris, Peter V Giannoudis, Fujian Song
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is licensed in Europe for open tibia fractures treated with unreamed nails. However, there is limited data available on the specific use of rhBMP-2 in combination with unreamed nails for open tibia fractures. The intention of the current study was to evaluate the medical and health-economic effects of rhBMP-2 in Gustilo-Anderson grade III open tibia fractures treated with unreamed nails based on individual patient data from two previously published studies...
November 2015: Injury
https://www.readbyqxmd.com/read/26287392/single-incision-total-proctocolectomy-and-ileal-pouch-anal-anastomosis-in-pediatric-patients-lessons-learned
#20
Avraham Schlager, Ragavan V Siddharthan, Matthew T Santore, Ozlem Balci, Matthew S Clifton, Kurt F Heiss
BACKGROUND: Total proctocolectomy (TPC) and ileal pouch anal anastomosis (IPAA) have become the standard of care for patients with ulcerative colitis refractory to medical management. The purpose of our study is to show our single-site approach and to identify maneuvers that improve efficiency. MATERIALS AND METHODS: We retrospectively reviewed patients who underwent single-site three-stage TPC-IPAA for ulcerative colitis at our institution. Primary outcomes included operative time, conversion from single site to standard laparoscopy, time to oral intake and stoma function, postoperative complications, and length of stay...
September 2015: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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