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https://www.readbyqxmd.com/read/29439334/what-do-we-know-about-behavioral-crises-in-dementia-a-systematic-review
#1
Tamara Backhouse, Julieta Camino, Eneida Mioshi
BACKGROUND: Behavioral crises in dementia are represented by a wide variety of symptoms, regularly require external intervention from professionals, and are reported as a risk factor for hospital admission. Little is known about the factors that are associated with them. OBJECTIVE: To determine the factors associated with dementia-related behavioral crises. METHODS: We searched MEDLINE, CINAHL, PsycINFO, EMBASE, and AMED databases. An additional lateral search including reference lists was conducted...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29436288/psychological-interventions-for-treating-neuropsychiatric-consequences-of-acquired-brain-injury-a-systematic-review
#2
Daan P J Verberne, Peggy J J Spauwen, Caroline M van Heugten
Anxiety, aggression/agitation, apathy and disinhibition are common neuropsychiatric consequences of acquired brain injury (ABI); these consequences can cause functional impairment and lead to reduced social integration. This systematic review aims to provide an examination of the current evidence on psychological interventions for treating these consequences. Two reviewers selected potential relevant articles, retrieved from five literature databases; methodological quality was assessed and appraised. A total of 5207 studies were found, of which 43 were included: 21 studies for anxiety, 18 for aggression, two studies for apathy, and six for disinhibition...
February 13, 2018: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/29433934/evidence-based-review-of-pharmacotherapy-for-acute-agitation-part-2-safety
#3
Leslie S Zun
BACKGROUND: The management of acute agitation in the emergency department often requires the administration of rapid-acting antipsychotic agents. However, there are few comparative studies and little guidance regarding the risks associated with use of such drugs in the acute setting. OBJECTIVE: This structured evidence-based review compared the safety of antipsychotic pharmacotherapies for acute agitation using data from randomized controlled trials identified by a literature search of the PubMed database...
February 9, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29432396/gathering-tips-from-carers-to-support-people-with-dementia-an-adaptation-of-the-top-5-program-for-community-use
#4
Kerrie Westaway, Oliver Frank, Russell Shute, Anna Moffat, Vanessa LeBlanc, Debra Rowett, Natalie Blacker, Elizabeth Roughead
AIM: Behavioral and psychological symptoms of dementia are often managed inappropriately with antipsychotic medicines. The TOP 5 program, which involves recording up to five relevant and meaningful tips that assist in personalizing care for the person with dementia, has been tested in the hospital setting and transitions of care in Australia, and has been found to be useful. Our study aimed to adapt the TOP 5 program as a strategy to support people with dementia in a primary care setting and to test the acceptability of our adapted TOP 5 program materials...
February 9, 2018: International Journal of Evidence-based Healthcare
https://www.readbyqxmd.com/read/29424552/differences-in-neuropsychiatric-symptoms-between-nursing-home-residents-with-young-onset-dementia-and-late-onset-dementia
#5
Britt Appelhof, Christian Bakker, Jeannette C L Van Duinen-van Den IJssel, Sandra A Zwijsen, Martin Smalbrugge, Frans R J Verhey, Marjolein E de Vugt, Sytse U Zuidema, Raymond T C M Koopmans
OBJECTIVE: The aims of the current study are (1) to explore the differences in neuropsychiatric symptoms (NPS) between young-onset dementia (YOD) and late-onset dementia (LOD), and (2) to investigate whether the possible differences can be attributed to differences in dementia subtype, gender, psychotropic drug use (PDU), or dementia severity. METHOD: Three hundred and eighty-six nursing home (NH) residents with YOD and 350 with LOD were included. Multilevel modeling was used to compare NPS between the groups ...
February 9, 2018: Aging & Mental Health
https://www.readbyqxmd.com/read/29406365/acute-pain-assessment-in-sedated-patients-in-the-post-anesthesia-care-unit
#6
Sherily Pereira-Morales, Carmen Mabel Arroyo-Novoa, Annete Wysocki, Lucille Sanzero Eller
CONTEXT: Acute postoperative pain remains inadequately assessed and managed. A valid instrument that assesses acute pain in sedated Post-Anesthesia Care Unit (PACU) patients is needed. OBJECTIVES: Two behavioral pain assessment instruments, the Non-Verbal Pain Scale Revised (NVPS-R) and Critical Care Pain Observation Tool (CPOT), were used to determine if these instruments adequately assess acute pain in the PACU. METHODS: A crossover study design was used...
February 5, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29405806/delayed-sequence-intubation-by-intensive-care-flight-paramedics-in-victoria-australia
#7
Jacinta Waack, Matthew Shepherd, Emily Andrew, Stephen Bernard, Karen Smith
OBJECTIVE: Delayed sequence intubation (DSI) involves the administration of ketamine to facilitate adequate preoxygenation in the agitated patient. DSI was introduced into the Clinical Practice Guideline for Intensive Care Flight Paramedics in Victoria in late 2013. We aimed to describe the clinical characteristics of patients receiving DSI. METHODS: A retrospective analysis was undertaken of patients who received DSI between January 1, 2014, and December 31, 2016, during both primary response and retrieval missions...
February 6, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29403132/can-plasticity-transform-functions-in-neurodegeneration-in-children-as-well-as-adults-an-observational-study
#8
Sadanandavalli Retnaswami Chandra, Safwan Ahamed, Chandra Sasitharan Vidhya Annapoorni
Introduction: Creativity is a physiological need based biological function very essential for survival. However, generally in disorders of progressive cognitive dysfunction creative skills are lost. However there are situations where these potentials are temporarily enhanced. Patients and Methods: We did an observational study of children and adults, 5 adults and 2 childrens, who showed extraordinary creativity evaluated based on evidence shown by patient, peers and re produced in test situation...
January 2018: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29402385/-seclusion-and-restraint-from-prescription-to-decision
#9
T Mauras, A Perony, J Yadak, A Velasco, P Goudal, J-L Marcel
Psychiatric care has always included patients in crisis who are potentially dangerous or agitated. Faced with the many issues they may encounter, the therapeutic relationship has always been prioritized over all other considerations. However, the practice of seclusion and restraint has been steadily increasing in the past few decades. Their use is becoming customary rather than exceptional and consequently fosters less thought by the care teams. In the Healthcare System Modernization Act of January 26th, 2016, the lawmakers sought to underline the freedom-destroying nature of these practices and the necessity of their regulation...
February 2, 2018: L'Encéphale
https://www.readbyqxmd.com/read/29395692/approach-to-the-agitated-emergency-department-patient
#10
Michael Gottlieb, Brit Long, Alex Koyfman
BACKGROUND: Acute agitation is a common occurrence in the emergency department (ED) that requires rapid assessment and management. OBJECTIVE: This review provides an evidence-based summary of the current ED evaluation and management of acute agitation. DISCUSSION: Acute agitation is an increasingly common presentation to the ED and has a broad differential diagnosis including metabolic, neurologic, infectious, toxicologic, and psychiatric etiologies...
January 29, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29380567/-metabolic-engineering-of-e-%C3%AE-farnesene-synthase-genes-for-aphid-resistant-genetically-modified-plants
#11
Dianyong Jia, Shiqing Gao, Pengfei Duan, Jibao Chen, Fengxia Tian, Xiudao Yu
Aphids are major agricultural pests that cause significant yield losses of crops each year. (E)-β-farnesene (EβF), as the main component of the aphid alarm pheromones, can interrupt aphid feeding and cause other conspecies in the vicinity to become agitated or disperse from their host plant. Furthermore, EβF can function as a kairomone in attracting aphid predators. EβF synthase genes, which encode enzymes that convert farnesyl diphosphate (FPP) to the acyclic sesquiterpene EβF, have been isolated and characterized from peppermint (Mentha × piperita and Mentha asiatica), Yuzu (Citrus junos), Douglas fir (Pseudotsuga menziesii), sweet wormwood (Artemisia annua) and chamomile (Matricaria recutita), respectively...
January 25, 2018: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://www.readbyqxmd.com/read/29372070/a-feasibility-study-of-a-randomised-controlled-trial-to-examine-the-impact-of-the-abcde-bundle-on-quality-of-life-in-icu-survivors
#12
Kellie Sosnowski, Marion L Mitchell, Hayden White, Lynette Morrison, Joanne Sutton, Jessica Sharratt, Frances Lin
Background: Early rehabilitation has been found to prevent delirium and weakness that can hamper the recovery of intensive care unit (ICU) survivors. Integrated clinical practice guidelines for managing patient pain, agitation and delirium (PAD) have been developed. The Awakening and Breathing Coordination, Delirium monitoring/management, and Early exercise/mobility (ABCDE) bundle provides a strategy to implement PAD guidelines into everyday clinical practice. However, there is limited evidence on the effectiveness of the ABCDE bundle in the literature...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29363929/best-practices-in-managing-child-and-adolescent-behavioral-health-emergencies-digest
#13
Vera Feuer, Joshua Rocker, Babar M Saggu, Jason M Andrus, Molly Wormley
Behavioral health emergencies most commonly present as depression, suicidal behavior, aggression, and severe disorganization. Emergency clinicians should avoid relying solely on past medical history or previous psychiatric diagnoses that might prematurely rule out medical pathologies. Treatments for behavioral health emergencies consist of de-escalation interventions aimed at preventing agitation, aggression, and harm. This issue reviews medical pathologies and underlying causes that can result in psychiatric presentations and summarizes evidence-based practices to evaluate, manage, and refer patients with behavioral health emergencies...
January 22, 2018: Pediatric Emergency Medicine Practice
https://www.readbyqxmd.com/read/29361326/evidence-based-review-of-pharmacotherapy-for-acute-agitation-part-1-onset-of-efficacy
#14
Leslie S Zun
BACKGROUND: The main goal of antipsychotic medication in the management of acute agitation in the emergency department is to rapidly induce calm without oversedation, enabling patients to participate in their own care. However, there is a paucity of comparative studies, particularly with newer fast-acting second-generation antipsychotic agents. OBJECTIVE OF THE REVIEW: This structured evidence-based review compared the onset of efficacy of antipsychotic treatments for acute agitation using data from randomized controlled trials identified by a literature search of the PubMed database...
January 17, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29359952/pharmacological-management-of-agitation-among-individuals-with-moderate-to-severe-acquired-brain-injury-a-systematic-review
#15
Swati Mehta, Amanda McIntyre, Shannon Janzen, Jerome Iruthayarajah, Ali Bateman, Robert Teasell
OBJECTIVE: To conduct a systematic review examining the effectiveness of pharmacological management of agitation among individuals with acquired brain injury (ABI). DATA SOURCES: MEDLINE, CINAHL, EMBASE, and PsycINFO databases were searched for all relevant articles published in English from 1980 to January 2016. STUDY SELECTION: Studies were included for analysis all participants had moderate to severe ABI, n ≥ 3, and a pharmacological intervention was provided for the treatment of agitation and its effectiveness was assessed...
January 23, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29356677/caring-for-seniors-living-with-dementia-means-caring-for-their-caregivers-too
#16
Annie Poirier, Philippe Voyer, France Légaré, Michèle Morin, Holly O Witteman, Edeltraut Kröger, Bernard Martineau, Charo Rodríguez, Anik Mc Giguere
To improve the care of seniors living with dementia, current initiatives typically target better identification and treatment of the patient. Our recent survey, however, shows we should also focus more on the needs of the informal caregivers who care for this population in primary care settings. This three-round Delphi survey sought caregivers' views on the most frequent and difficult decisions that seniors with dementia, their informal caregivers, and health care providers face in primary care settings in the province of Quebec...
January 22, 2018: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29353776/changes-in-microcystis-aeruginosa-cell-integrity-and-variation-in-microcystin-lr-and-proteins-during-tanfloc-flocculation-and-floc-storage
#17
Jun Hou, Zijun Yang, Peifang Wang, Chao Wang, Yangyang Yang, Xun Wang
The objective of this study was to determine the influence of Tanfloc on Microcystis aeruginosa cell integrity, microcystin-LR (MC-LR), and proteins during flocculation and floc storage. The effects of Tanfloc addition, stirring, and floc storage time were considered to minimize cell damage and the release of MC-LR and proteins. Optimal flocculation conditions (Tanfloc dosage 10.42 mg L-1, rapid agitation for 0.36 min at 568.88 rpm and slow agitation for 14.14 min at 12.1 rpm) were obtained using the response surface methodology...
January 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29353710/prevalence-and-predictors-of-difficulty-accessing-the-mouths-of-intubated-critically-ill-adults-to-deliver-oral-care-an-observational-study
#18
Craig M Dale, Orla Smith, Lisa Burry, Louise Rose
BACKGROUND: Oral care of intubated patients is essential to the prevention of infection and patient discomfort. However, barriers to oral access and delivery of oral care have received little attention. OBJECTIVE: To determine prevalence and predictors of oral access difficulty. DESIGN: A prospective, observational, multi-center study. SETTINGS: Four intensive care units in Toronto, Canada. PARTICIPANTS: Adult patients orally intubated for ≥48 h...
December 28, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29345395/patient-carer-and-public-involvement-in-major-system-change-in-acute-stroke-services-the-construction-of-value
#19
Christopher McKevitt, Angus I G Ramsay, Catherine Perry, Simon J Turner, Ruth Boaden, Charles D A Wolfe, Naomi J Fulop
BACKGROUND: Patient and public involvement is required where changes to care provided by the UK National Health Service are proposed. Yet involvement is characterized by ambiguity about its rationales, methods and impact. AIMS: To understand how patients and carers were involved in major system changes (MSCs) to the delivery of acute stroke care in 2 English cities, and what kinds of effects involvement was thought to produce. METHODS: Analysis of documents from both MSC projects, and retrospective in-depth interviews with 45 purposively selected individuals (providers, commissioners, third-sector employees) involved in the MSC...
January 18, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29344342/frontotemporal-dementia-latest-evidence-and-clinical-implications
#20
REVIEW
Juan Joseph Young, Mallika Lavakumar, Deena Tampi, Silpa Balachandran, Rajesh R Tampi
Background: Frontotemporal dementia (FTD) describes a cluster of neurocognitive syndromes that present with impairment of executive functioning, changes in behavior, and a decrease in language proficiency. FTD is the second most common form of dementia in those younger than 65 years and is expected to increase in prevalence as the population ages. This goal in our review is to describe advances in the understanding of neurobiological pathology, classification, assessment, and treatment of FTD syndromes...
January 2018: Therapeutic Advances in Psychopharmacology
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