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Aortic stiffness

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https://www.readbyqxmd.com/read/28416296/hiv-infection-and-aortic-stiffness
#1
REVIEW
Luisa Helena Maia Leite, Ariel Cohen, Franck Boccara
People living with human immunodeficiency virus (HIV) infection and receiving antiretroviral therapy now have the same life expectancy as the general population. However, they have a higher risk of atherosclerotic cardiovascular events because of a complex and polyfactorial vasculopathy, combining the effects of antiretroviral therapy, the HIV virus itself, immune activation, chronic inflammation and metabolic disturbances. Whether people living with HIV infection experience increased vascular aging compared with the general population remains controversial...
April 14, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28415122/p1138cardiac-shear-wave-velocity-in-healthy-individuals
#2
M Strachinaru, M L Geleijnse, J G Bosch, N De Jong, Afw Van Der Steen, B M Van Dalen, H J Vos
Background: The closure of the valves generates shear waves in the heart walls. The propagation velocity of shear waves relates to stiffness. This could potentially be used to estimate the stiffness of the myocardium, with huge potential implications in pathologies characterized by a deterioration of the diastolic properties of the left ventricle. In an earlier phantom study we already validated shear wave tracking with a clinical ultrasound system in cardiac mode. Purpose: In this study we aimed to measure the shear waves velocity in normal individuals...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28415116/p1007aortic-root-diameters-and-aortic-regurgitation-in-hypertensive-patients-and-normal-subjects
#3
O Vriz, N B Bertn, G Brosolo, E Bossone
Purpose: : The association between aortic root diameters and aortic regurgitation in hypertension (HT) is disputed with lack of understanding of the underline mehanisms lT. We investigate the relationship between aortic root diameters and aortic regurgitation in newly diagnosed and never treated hypertensive patients and in a group healthy subjects. Method: Participants were 175 hypertensives (42 F and 133 M) and 305 normotensives (134 F, 168 M) age matched (mean age 52...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28415103/p673improvement-of-arterial-stiffness-and-myocardial-deformation-in-patients-with-poorly-controlled-diabetes-mellitus-type-2-after-optimization-of-antidiabetic-medication
#4
I Ikonomidis, G Pavlidis, V Lambadiari, F Kousathana, H Triantafyllidi, M Varoudi, D Vlastos, S Vlachos, G Dimitriadis, J Lekakis
Background: Arterial stiffness is associated with increased risk for cardiovascular disease. The purpose of this study is to investigate the arterial stiffness and myocardial deformation in patients with poorly controlled diabetes mellitus type 2 before and after glycemic control by optimal medication. Methods: In 50 patients with uncontrolled type 2 diabetes(age:52±10years)and 25 controls of similar age and sex and no atherosclerotic risk factors we measured at baseline and 6 months after glycemic control a) carotid-femoral pulse wave velocity(PWVc m/sec-Complior SP ALAM),central systolic blood pressure(cSBP -mmHg),augmentation index(AI%), of the aortic pulse wave(ArteriographTensioMed) b)S',E'(m/sec)andE'/A'of mitral annulus by Tissue Doppler c)LV longitudinal strain(GLS-%),systolic(LongSr-l/sec)and diastolic(LongSrE-l/sec)strain rate, twisting(Tw-deg),peak twisting(Tw)and untwisting(unTw-deg/sec)velocity using speckle tracking echocardiography...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28403173/reference-values-of-brachial-ankle-pulse-wave-velocity-according-to-age-and-blood-pressure-in-a-central-asia-population
#5
Gulinuer Yiming, Xianhui Zhou, Wenkui Lv, Yi Peng, Wenhui Zhang, Xinchun Cheng, Yaodong Li, Qiang Xing, Jianghua Zhang, Qina Zhou, Ling Zhang, Yanmei Lu, Hongli Wang, Baopeng Tang
BACKGROUND: Brachial-ankle pulse wave velocity (baPWV), a direct measure of aortic stiffness, has increasingly become an important assessment for cardiovascular risk. The present study established the reference and normal values of baPWV in a Central Asia population in Xinjiang, China. METHODS: We recruited participants from a central Asia population in Xinjiang, China. We performed multiple regression analysis to investigate the determinants of baPWV. The median and 10th-90th percentiles were calculated to establish the reference and normal values based on these categories...
2017: PloS One
https://www.readbyqxmd.com/read/28400456/diverging-effects-of-diabetes-mellitus-in-patients-with-peripheral-artery-disease-and-abdominal-aortic-aneurysm-and-the-role-of-advanced-glycation-end-products-artery-study-protocol-for-a-multicentre-cross-sectional-study
#6
L C de Vos, J Boersema, J L Hillebrands, C G Schalkwijk, R Meerwaldt, J C Breek, A J Smit, C J Zeebregts, J D Lefrandt
INTRODUCTION: Diabetes mellitus is a well-defined risk factor for peripheral artery disease (PAD), but protects against the development and growth of abdominal aortic aneurysm (AAA). Diabetes mellitus is associated with arterial stiffening and peripheral arterial media sclerosis. Advanced glycation end-products (AGEs) are increased in diabetes mellitus and cardiovascular disease. AGEs are known to form cross-links between proteins and are associated with arterial stiffness. Whether AGEs contribute to the protective effects of diabetes mellitus in AAA is unknown...
April 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28396534/aortic-brachial-arterial-stiffness-gradient-and-cardiovascular-risk-in-the-community-the-framingham-heart-study
#7
Teemu J Niiranen, Bindu Kalesan, Martin G Larson, Naomi M Hamburg, Emelia J Benjamin, Gary F Mitchell, Ramachandran S Vasan
A recent study reported that the aortic-brachial arterial stiffness gradient, defined as carotid-radial/carotid-femoral pulse wave velocity (PWV ratio), predicts all-cause mortality better than carotid-femoral pulse wave velocity (CFPWV) alone in dialysis patients. However, the prognostic significance of PWV ratio for cardiovascular disease (CVD) in the community remains unclear. Accordingly, we assessed the correlates and prognostic value of the PWV ratio in 2114 Framingham Heart Study participants (60±10 years; 56% women) free of overt CVD...
April 10, 2017: Hypertension
https://www.readbyqxmd.com/read/28395967/carotid-femoral-pulse-wave-velocity-assessed-by-ultrasound-a-study-with-echotracking-technology
#8
Mathieu Collette, Carlo Palombo, Carmela Morizzo, Sara Sbragi, Michaela Kozakova, Georges Leftheriotis
Described here is a new method for determination of carotid-femoral pulse wave velocity (PWV) based on arterial diameter waveform recording by an ultrasound system. The study was carried out on 120 consecutive patients. Carotid-femoral PWV was determined using a tonometric technique (PWVpp, PulsePen, DiaTecne, Milan, Italy) and an echotracking ultrasound system (PWVet, E-Track, Aloka, Tokyo, Japan). The relationship between PWVpp and PWVet was evaluated by linear regression and Bland-Altman analysis. There was excellent agreement between PWVet and PWVpp (Pearson's r = 0...
April 7, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28391000/prognostic-role-of-subclinical-left-ventricular-systolic-dysfunction-evaluated-by-speckle-tracking-echocardiography-in-rheumatoid-arthritis
#9
Giovanni Cioffi, Ombretta Viapiana, Federica Ognibeni, Andrea Dalbeni, Alessandro Giollo, Davide Gatti, Luca Idolazzi, Giorgio Faganello, Andrea Di Lenarda, Maurizio Rossini
BACKGROUND: Speckle-tracking echocardiography allows early detection of subclinical left ventricular systolic dysfunction (LVSD) in patients with rheumatoid arthritis (RA). In this prospective study, we assessed the prevalence and the prognostic role of subclinical LVSD detected by speckle-tracking echocardiography in RA patients. METHODS: Two-dimensional global longitudinal strain (GLS) and global circumferential strain (GCS) were measured in 209 RA patients without overt cardiac disease...
April 6, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28382958/role-of-nebivolol-in-the-control-and-management-of-central-aortic-blood-pressure-in-hypertensive-patients
#10
REVIEW
C Borghi, M C Acelajado, Y Gupta, S Jain
Measurement of blood pressure (BP) using a brachial cuff sphygmomanometer is universally accepted for the diagnosis of hypertension and prediction of cardiovascular diseases. However, brachial systolic BP does not represent actual systolic BP in the central arteries which encounter cardiac load directly. Due to wave amplification from central to peripheral arteries, a significant difference exists between the two. Central BP measurements also account for arterial stiffness, vessel branching and vascular mechanics, unlike brachial BP...
April 6, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28379892/evaluation-of-arterial-stiffness-by-finger-toe-pulse-wave-velocity-optimization-of-signal-processing-and-clinical-validation
#11
Hasan Obeid, Hakim Khettab, Louise Marais, Magid Hallab, Stéphane Laurent, Pierre Boutouyrie
BACKGROUND: Carotid-femoral pulse wave velocity (PWV) (cf-PWV) is the gold standard for measuring aortic stiffness. Finger-toe PWV (ft-PWV) is a simpler noninvasive method for measuring arterial stiffness. Although the validity of the method has been previously assessed, its accuracy can be improved. ft-PWV is determined on the basis of a patented height chart for the distance and the pulse transit time (PTT) between the finger and the toe pulpar arteries signals (ft-PTT). METHOD: The objective of the first study, performed in 66 patients, was to compare different algorithms (intersecting tangents, maximum of the second derivative, 10% threshold and cross-correlation) for determining the foot of the arterial pulse wave, thus the ft-PTT...
April 4, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28377229/bending-the-rules-in-transfemoral-tavi-with-the-sapien-3-overcoming-severe-iliac-tortuosity
#12
Jonathan Michel, Antonio H Frangieh, Ilka Ott, A M Kasel
Whilst the worldwide uptake of transcatheter aortic valve implantation (TAVI) over the last 10 years has been dramatic, iliac tortuosity remains a potential barrier to the most commonly chosen access route via the femoral artery. We describe the challenges posed by severe iliac tortuosity during transfemoral TAVI and contrast a difficult procedure - at the limit of the capability of current device delivery technology - with a straightforward implantation. The use of pre-procedural multi-detector computed tomography to assess the vasculature and a bilateral stiff wire technique for managing iliofemoral tortuosity are discussed...
March 15, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28376407/baseline-predictors-of-aortic-stiffness-progression-among-multi-ethnic-asians-with-type-2-diabetes
#13
Mei Chung Moh, Chee Fang Sum, Subramaniam Tavintharan, Keven Ang, Simon Biing Ming Lee, Wern Ee Tang, Su Chi Lim
BACKGROUND AND AIMS: This 3-year prospective study aimed to identify baseline parameters that predicted the progression of carotid-femoral pulse wave velocity (cf-PWV), which was used to evaluate aortic stiffness, among Singapore's multi-ethnic Asians with type 2 diabetes (T2DM). METHODS: The cf-PWV was measured by the gold-standard tonometry method in 994 T2DM subjects at baseline and follow-up. The annual rate of cf-PWV change was calculated, and individuals above the 90(th) percentile with rate≥1...
January 27, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28374647/the-associations-of-cardiorespiratory-fitness-adiposity-and-sports-participation-with-arterial-stiffness-in-youth-with-chronic-diseases-or-physical-disabilities
#14
Eero A Haapala, Kristel Lankhorst, Janke de Groot, Maremka Zwinkels, Olaf Verschuren, Harriet Wittink, Frank Jg Backx, Anne Visser-Meily, Tim Takken
Background The evidence on the associations of cardiorespiratory fitness, body adiposity and sports participation with arterial stiffness in children and adolescents with chronic diseases or physical disabilities is limited. Methods Altogether 140 children and adolescents with chronic diseases or physical disabilities participated in this cross-sectional study. Cardiorespiratory fitness was assessed using maximal exercise test with respiratory gas analyses either using shuttle run, shuttle ride, or cycle ergometer test...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28371741/carotid-flow-pulsatility-is-higher-in-women-with-greater-decrement-in-gait-speed-during-multi-tasking
#15
Joaquin U Gonzales, C Roger James, Hyung Suk Yang, Daniel Jensen, Lee Atkins, Kareem Al-Khalil, Michael O'Boyle
AIM: Central arterial hemodynamics is associated with cognitive impairment. Reductions in gait speed during walking while performing concurrent tasks known as dual-tasking (DT) or multi-tasking (MT) is thought to reflect the cognitive cost that exceeds neural capacity to share resources. We hypothesized that central vascular function would associate with decrements in gait speed during DT or MT. METHODS: Gait speed was measured using a motion capture system in 56 women (30-80y) without mild-cognitive impairment...
March 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28364019/arterial-viscoelasticity-role-in-the-dependency-of-pulse-wave-velocity-on-heart-rate-in-conduit-arteries
#16
Hanguang Xiao, Isabella Tan, Mark Butlin, Decai Li, Alberto P Avolio
Experimental investigations have established that the stiffness of large arteries has a dependency on acute heart rate (HR) changes. However, possible underlying mechanisms inherent in this HR dependency have not been well established. This study aimed to explore a plausible viscoelastic mechanism by which HR exerts an influence on arterial stiffness. A multi-segment transmission line model of the human arterial tree incorporating fractional viscoelastic components in each segment was used to investigate the effect of varying fractional order parameter (α) of viscoelasticity on the dependence of aortic arch to femoral artery pulse wave velocity (afPWV) on HR...
March 31, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28360227/increased-arterial-stiffness-is-an-independent-predictor-of-renal-function-decline-in-patients-with-type-2-diabetes-mellitus-younger-than-60%C3%A2-years
#17
Nikolaos Fountoulakis, Chiraag Thakrar, Kishan Patel, Giancarlo Viberti, Luigi Gnudi, Janaka Karalliedde
BACKGROUND: The objective of this study was to evaluate whether aortic pulse wave velocity (Ao-PWV) predicts estimated glomerular filtration rate (eGFR) decline in patients with type 2 diabetes mellitus. METHODS AND RESULTS: This prospective single-center cohort study investigated 211 type 2 diabetes mellitus patients with eGFR ≥45 mL/min with a baseline mean age of 60.1 years (range, 30-82 years). The mean±SD baseline eGFR was 85±26.1 mL/min. We divided the cohort into 2 groups above (n=117, "older") and below (n=94, "younger") the mean age to evaluate whether Ao-PWV predicted progression of kidney disease differentially in older and younger patients...
March 30, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28359794/multilayered-parallel-endografting-for-urgent-endovascular-repair-of-a-severely-angulated-thoracoabdominal-aortic-aneurysm
#18
Sukgu M Han, Sarah Wartman, Sung W Ham, Eric C Kuo, Vincent L Rowe, Fred A Weaver
Total endovascular repair of TAAA using branched, fenestrated stent-grafts have been performed with promising midterm results. However, severe angulation of the aorta as well as close proximity of the visceral and renal artery ostia pose a significant technical challenge in designing and implanting branched, fenestrated stent-grafts. Parallel grafting offers an alternative technique, allowing an urgent, or emergent total endovascular repair of symptomatic, or ruptured TAAA. We describe a technique of 4-vessel incorporation in a total endovascular repair of TAAA, using multi-layered parallel endografting via bilateral femoral and unilateral brachial access...
March 27, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28350575/influence-of-carotid-atherosclerotic-plaques-on-pulse-wave-assessment-with-arterial-tonometry
#19
Andrea Grillo, Giulia Simon, Paolo Salvi, Matteo Rovina, Corrado Baldi, Ilaria Prearo, Stella Bernardi, Bruno Fabris, Andrea Faini, Gianfranco Parati, Moreno Bardelli, Renzo Carretta
OBJECTIVE: Aortic stiffness and central pressure measurements have become increasingly important for the overall estimation of cardiovascular risk. The aim of this study is to verify whether the presence of stenosis in the carotid arteries due to atherosclerotic plaques may induce a bias in the measurement of carotid-femoral pulse wave velocity (PWV) and in the analysis of central pulse waveform variables assessed by carotid tonometry. METHODS: Eighty-four patients (age: 67...
March 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28336153/quantification-and-comparison-of-the-mechanical-properties-of-four-human-cardiac-valves
#20
Thuy Pham, Fatiesa Sulejmani, Erica Shin, Di Wang, Wei Sun
OBJECTIVE: Although having the same ability to permit unidirectional flow within the heart, the four main valves-the mitral valve (MV), aortic (AV), tricuspid (TV) and pulmonary (PV) valves-experience different loading conditions; thus, they exhibit different structural integrity from one another. Most research on heart valve mechanics have been conducted mainly on MV and AV or an individual valve, but none quantify and compare the mechanical and structural properties among the four valves from the same aged patient population whose death was unrelated to cardiovascular disease...
March 20, 2017: Acta Biomaterialia
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