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Aortic stiffness

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https://www.readbyqxmd.com/read/28748188/arterial-stiffness-in-symptomatic-smokers-with-normal-lung-function
#1
Nicola Scichilone, Antonino Tuttolomondo, Carlo Maida, Alida Benfante, Jessica Peluso, Anna Cirrincione, Valerio Vassallo, Antonio Pinto
Chronic obstructive pulmonary disease (COPD) is associated with cardiovascular morbidity and mortality. Arterial stiffness and endothelial dysfunction index are validated surrogate cardiovascular markers and are increased in subjects with COPD. We tested whether increased arterial stiffness and endothelial dysfunction occur in symptomatic smokers with no evidence of bronchial obstruction. Clinical and lung functional assessments were conducted in smoker subjects with chronic respiratory symptoms and in COPD patients...
July 2017: ERJ Open Research
https://www.readbyqxmd.com/read/28745686/-effects-of-keto-amino-acids-and-a-low-protein-diet-on-the-nutritional-status-of-patients-with-stages-3b-4-chronic-kidney-disease
#2
S Yu Milovanova, Yu S Milovanov, M V Taranova, I A Dobrosmyslov
AIM: To evaluate the efficacy of keto/amino acids in maintaining protein balance and preventing mineral metabolic disturbances and the development of uremic hyperparathyroidism in the long-term use of a low-protein diet (LPD) in patients with Stages 3B-4 chronic kidney disease (CKD). SUBJECTS AND METHODS: Ninety patients with CKD caused by chronic latent glomerulonephritis in 65 patients and chronic tubulointerstitial nephritis of various etiologies (gout, drug-induced, and infection) in 25 were examined...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28733312/baseline-aortic-pulse-wave-velocity-is-associated-with-central-and-peripheral-pressor-responses-during-the-cold-pressor-test-in-healthy-subjects
#3
Anastasiya Borner, Kyle Murray, Claire Trotter, James Pearson
Cold environmental temperatures increase sympathetic nerve activity and blood pressure, and increase the risk of acute cardiovascular events in aged individuals. The acute risk of cardiovascular events increases with aortic pulse wave velocity as well as elevated central and peripheral pulse pressures. The aim of this study was to examine the independent influence of aortic pulse wave velocity upon central and peripheral pressor responses to sympathetic activation via the cold pressor test (CPT). Twenty-two healthy subjects (age: 18-73 years) completed a CPT with the left hand immersed in 2-4°C water for 3 min...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28728780/detecting-regional-stiffness-changes-in-aortic-aneurysmal-geometries-using-pressure-normalized-strain
#4
Doran S Mix, Ling Yang, Camille C Johnson, Nathan Couper, Ben Zarras, Isaac Arabadjis, Lauren E Trakimas, Michael C Stoner, Steven W Day, Michael S Richards
Transabdominal ultrasound elasticity imaging could improve the assessment of rupture risk for abdominal aortic aneurysms by providing information on the mechanical properties and stress or strain states of vessel walls. We implemented a non-rigid image registration method to visualize the pressure-normalized strain within vascular tissues and adapted it to measure total strain over an entire cardiac cycle. We validated the algorithm's performance with both simulated ultrasound images with known principal strains and anatomically accurate heterogeneous polyvinyl alcohol cryogel vessel phantoms...
July 17, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28728487/feasibility-and-characteristics-of-arterial-stiffness-measurement-in-preschool-children
#5
Maaike M Vanderschuren, Cuno Spm Uiterwaal, Cornelis K van der Ent, Jacobien B Eising
Background Arterial stiffness is an important predictor of cardiovascular risk in adult life. Increased arterial stiffness can also be present in children and may be associated with several other cardiovascular risk factors. Until now, however, we know little about measuring arterial stiffness in preschool children. In this study, we assessed the feasibility of measuring arterial stiffness in preschool children and explored possible determinants related to arterial stiffness at this age. Methods We studied 168 healthy children, aged 3...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28721164/influence-of-half-marathon-race-on-aortic-stiffness-in-amateur-runners
#6
Marzena Staniszewska, Artur Pudło, Andrzej Pawlik
No abstract text is available yet for this article.
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28719470/diurnal-variation-and-repeatability-of-arterial-stiffness-and-cardiac-output-measurements-in-the-third-trimester-of-uncomplicated-pregnancy
#7
Mohamed W Osman, Francesca Leone, Mintu Nath, Asma Khalil, David R Webb, Thompson G Robinson, Hatem A Mousa
AIM: To investigate same day repeated measures and diurnal variation of arterial stiffness, cardiac output (CO), stroke volume (SV) and total peripheral resistance (TPR) during the third trimester of normal pregnancy. METHODOLOGY: Pulse wave velocity (PWV) and augmentation index (AIx) were recorded using the Arteriograph, while CO, SV and TPR were recorded using noninvasive cardiac output monitoring. The measurements were obtained in the third trimester of pregnancy from 21 healthy pregnant women at four time points (morning, afternoon, evening and midnight) over a 24-h period...
July 14, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28713285/amiloride-improves-endothelial-function-and-reduces-vascular-stiffness-in-female-mice-fed-a-western-diet
#8
Luis A Martinez-Lemus, Annayya R Aroor, Francisco I Ramirez-Perez, Guanghong Jia, Javad Habibi, Vincent G DeMarco, Brady Barron, Adam Whaley-Connell, Ravi Nistala, James R Sowers
Obese premenopausal women lose their sex related cardiovascular disease protection and develop greater arterial stiffening than age matched men. In female mice, we have shown that consumption of a Western diet (WD), high in fat and refined sugars, is associated with endothelial dysfunction and vascular stiffening, which occur via activation of mineralocorticoid receptors and associated increases in epithelial Na(+) channel (ENaC) activity on endothelial cells (EnNaC). Herein our aim was to determine the effect that reducing EnNaC activity with a very-low-dose of amiloride would have on decreasing endothelial and arterial stiffness in young female mice consuming a WD...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28713284/greater-progression-of-age-related-aortic-stiffening-in-adults-with-poor-trunk-flexibility-a-5-year-longitudinal-study
#9
Yuko Gando, Haruka Murakami, Kenta Yamamoto, Ryoko Kawakami, Harumi Ohno, Susumu S Sawada, Nobuyuki Miyatake, Motohiko Miyachi
Purpose: Having a low level of physical fitness, especially cardiorespiratory fitness, appears to accelerate age-related aortic stiffening. Whereas, some studies have reported that trunk flexibility is a component of physical fitness, it is also negatively associated with arterial stiffening independent of cardiorespiratory fitness in cross-sectional studies. However, no long-term longitudinal study has determined whether poor trunk flexibility accelerates the progression of age-related aortic stiffening. We examined trunk flexibility and aortic stiffness progression in a 5-year longitudinal study...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28710615/aldosterone-antagonist-therapy-and-its-relationship-with-inflammation-fibrosis-thrombosis-mineral-bone-disorder-and-cardiovascular-complications-in-peritoneal-dialysis-pd-patients
#10
Rafał Donderski, Paweł Stróżecki, Beata Sulikowska, Magdalena Grajewska, Ilona Miśkowiec, Anna Stefańska, Joanna Siódmiak, Grażyna Odrowąż-Sypniewska, Jacek Manitius
BACKGROUND: High aldosterone level may contribute to pathogenesis of hypertension, vessels damage and cardiovascular system deterioration in chronic kidney disease patients. Besides its classical action via mineralocorticoid receptor, aldosterone is also involved in cell growth, inflammation, oxidative stress, endothelial dysfunction and exerts fibroproliferative effects. The aim of the study was to assess whether aldosterone antagonist treatment may influence serum level of inflammatory, fibrosis, thrombosis and mineral-bone metabolism markers in peritoneal dialysis (PD) patients and blood pressure, aortic stiffness, echocardiographic indices after 12 months of treatment...
July 14, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28704261/no-independent-association-between-pulse-wave-velocity-and-dementia-a-population-based-prospective-study
#11
Erik D Nilsson, Sölve Elmståhl, Lennart Minthon, Mats Pihlsgård, Peter M Nilsson, Oskar Hansson, Katarina Nägga
OBJECTIVE: Carotid-femoral pulse wave velocity (CFPWV), a marker of aortic stiffness, has been associated with cognitive test results and markers of cerebral small vessel disease, but its association with dementia has not been studied in detail. Our aim was to assess the association of CFPWV with prevalent and incident dementia in a large population-based study. METHODS: In total, CFPWV was measured in 3056 participants of the Malmö Diet and Cancer study 2007-2012 (age range 61-85 years)...
July 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28699368/impact-of-blood-pressure-lesion-level-and-physical-activity-on-aortic-augmentation-index-in-persons-with-sci
#12
Caitlyn G Katzelnick, Joseph P Weir, Nancy Chiaravalotti, Glenn Wylie, Trevor Dyson-Hudson, William A Bauman, Jill M Wecht
Individuals with chronic spinal cord injury (SCI) are at a heightened risk of cardiovascular disease (CVD) due to autonomic nervous system dysfunction, physical inactivity and increased inflammatory processes. Arterial stiffness (AS) is recognized as an independent risk factor for CVD and, specifically, pulse wave analysis (PWA) has proven to be a useful tool to predict and track structural arterial changes that reflect arteriosclerosis. The augmentation index (AI) can be used to estimate AS and is derived from the amplitude and timing of the blood pressure (BP) wave reflection in a peripheral artery...
July 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28687808/predictors-of-development-and-progression-of-retinopathy-in-patients-with-type-2-diabetes-importance-of-blood-pressure-parameters
#13
Claudia R L Cardoso, Nathalie C Leite, Eduardo Dib, Gil F Salles
Diabetic retinopathy (DR) is a chronic microvascular complication associated a worse prognosis. We aimed to evaluate the predictors of development/progression of DR in a cohort of 544 high-risk patients with type 2 diabetes who had annual ophthalmologic examinations over a median follow-up of 6 years. Ambulatory blood pressure (BP) monitoring and aortic stiffness by carotid-femoral pulse wave velocity were performed. Multivariate Cox survival analysis examined the independent predictors of development or progression of DR...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28684437/the-role-and-clinical-implications-of-diastolic-dysfunction-in-aortic-stenosis
#14
REVIEW
Polydoros N Kampaktsis, Damianos G Kokkinidis, Shing-Chiu Wong, Manolis Vavuranakis, Nikolaos J Skubas, Richard B Devereux
Diastolic dysfunction in aortic stenosis results primarily from left ventricular hypertrophy and myocardial fibrosis due to chronically elevated left ventricular systolic pressure. Currently, diastolic dysfunction does not have an explicit clinical role in management of patients with aortic stenosis. Studies have shown that improvement in diastolic dysfunction follows left ventricular remodelling after aortic valve replacement and that it occurs gradually or incompletely. Retrospective studies suggest that advanced grades of diastolic dysfunction at baseline are associated with increased mortality and adverse events even after aortic valve replacement...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28683960/arterial-stiffening-with-exercise-in-patients%C3%A2-with-heart-failure-and-preserved%C3%A2-ejection-fraction
#15
Yogesh N V Reddy, Mads J Andersen, Masaru Obokata, Katlyn E Koepp, Garvan C Kane, Vojtech Melenovsky, Thomas P Olson, Barry A Borlaug
BACKGROUND: Aortic stiffening and reduced nitric oxide (NO) availability may contribute to the pathophysiology of heart failure with preserved ejection fraction (HFpEF). OBJECTIVES: This study compared indices of arterial stiffness at rest and during exercise in subjects with HFpEF and hypertensive control subjects to examine their relationships to cardiac hemodynamics and determine whether exertional arterial stiffening can be mitigated by inorganic nitrite. METHODS: A total of 22 hypertensive control subjects and 98 HFpEF subjects underwent hemodynamic exercise testing with simultaneous expired gas analysis to measure oxygen consumption...
July 11, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28683504/initial-experience-with-the-transapical-access-for-tevar
#16
Andreas H Mahnken, Marc Irqsusi, Walter Hundt, Rainer G Moosdorf
Background The endovascular approach has become a mainstay in the treatment of aortic aneurysms. While the transfemoral approach is most commonly used, it is often inaccessible due to a vascular pathology, such as occlusion, tortuosity or heavy calcifications. The transapical access provides an alternative approach. The goal of this study is to report the feasibility of the transapical approach for total endovascular repair of thoracic aortic aneurysms (TEVAR). Methods Three patients with thoracic aortic aneurysms with inaccessible femoral arteries underwent TEVAR via the transapical approach...
August 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28683363/association-between-markers-of-arterial-stiffness-and-atrial-fibrillation-in-the-circulatory-risk-in-communities-study-circs
#17
Renzhe Cui, Kazumasa Yamagishi, Isao Muraki, Mina Hayama-Terada, Mitsumasa Umesawa, Hironori Imano, Yuanying Li, Ehab S Eshak, Tetsuya Ohira, Masahiko Kiyama, Takeo Okada, Akihiko Kitamura, Takeshi Tanigawa, Hiroyasu Iso
BACKGROUND AND AIMS: Limited evidence is available on the association between markers of arterial stiffness and the prevalence of atrial fibrillation among Asian populations. Therefore, we examined those associations in the Japanese population. METHODS: We conducted a cross-sectional population-based study of 4264 men and women aged 40-79 years. The augmentation index (AI), a marker of arterial stiffness, was calculated as the ratio of central pulse pressure/brachial pulse pressure, where the AI and central aortic pressure were measured by an automated tonometer: the HEM-9000AI device (Omron Healthcare co...
June 22, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28671855/free-weight-resistance-exercise-on-pulse-wave-reflection-and-arterial-stiffness-between-sexes-in-young-resistance-trained-adults
#18
J Derek Kingsley, Yu Lun Tai, Xian Mayo, Alaina Glasgow, Erica Marshall
We sought to determine the sex-specific effects of an acute bout of free-weight resistance exercise (RE) on pulse wave reflection (aortic blood pressures, augmentation index (AIx), AIx at 75 bpm (AIx@75), augmentation pressure (AP), time of the reflected wave (Tr), subendocardial viability ratio (SEVR)), and aortic arterial stiffness in resistance-trained individuals. Resistance-trained men (n = 14) and women (n = 12) volunteered to participate in the study. Measurements were taken in the supine position at rest, and 10 minutes after 3 sets of 10 repetitions at 75% 1-repetition maximum on the squat, bench press, and deadlift...
September 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28669329/effect-of-low-5-mg-vs-high-20-40-mg-rosuvastatin-dose-on-24h-arterial-stiffness-central-haemodynamics-and-non-alcoholic-fatty-liver-disease-in-patients-with-optimally-controlled-arterial-hypertension
#19
Eudoxia Mitsiou, Chrysoula Boutari, Vasilios Kotsis, Eleni Georgianou, Michael Doumas, Asterios Karagiannis, Vasilios G Athyros
OBJECTIVE: Arterial stiffness (AS) and non-alcoholic fatty liver diseases (NAFLD) are 2 related, prevalent, risk predictors of cardiovascular disease (CVD). We assessed the effect of low dose (5 mg/day) vs high dose (20-40 mg/day) rosuvastatin on aortic elasticity and central haemodynamics as well as on NAFLD in patients with arterial hypertension (AH). PATIENTS-METHODS: Forty patients with optimally controlled AH were randomised to 2 rosuvastatin doses and followed for 6 months...
June 30, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28665888/a-health-profile-associated-with-excessive-alcohol-use-independently-predicts-aortic-stiffness-over-10-years-in-black-south-africans
#20
Melissa Maritz, Carla M T Fourie, Johannes M van Rooyen, Iolanthe M Kruger, Aletta E Schutte
OBJECTIVE: Black populations exhibit higher arterial stiffness than whites and suffer a disproportionate burden of cardiovascular disease. It is therefore important to identify modifiable health behaviours predicting large artery stiffness in blacks. We examined whether traditional cardiovascular risk factors and health behaviours of black South Africans predict large artery stiffness 10 years later. METHODS: We included 650 HIV-free participants (32.8% men) and collected data in rural and urban areas of the North West Province in 2005 and 2015...
June 29, 2017: Journal of Hypertension
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