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https://www.readbyqxmd.com/read/28541199/3d-nonlinear-acoustic-inverse-scattering-algorithm-and-quantitative-results
#1
James Wiskin, David Borup, Elaine Iuanow, John Klock, Mark Lenox
We describe a novel 3D ultrasound technology, the Quantitative Transmission Ultrasound (QT Ultrasound®) system and algorithm to image a pendent breast in a water bath. Quantitative accuracy is verified using phantoms. Morphological accuracy is verified using cadaveric breast and in vivo images, and spatial resolution is estimated. This paper generalizes an earlier 2D algorithm to a full 3D inversion algorithm and shows the importance of such a 3D algorithm for artifact suppression as compared with the 2D algorithm...
May 23, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28533738/genetics-of-tinnitus-still-in-its-infancy
#2
REVIEW
Barbara Vona, Indrajit Nanda, Wafaa Shehata-Dieler, Thomas Haaf
Tinnitus is the perception of a phantom sound that affects between 10 and 15% of the general population. Despite this considerable prevalence, treatments for tinnitus are presently lacking. Tinnitus exhibits a diverse array of recognized risk factors and extreme clinical heterogeneity. Furthermore, it can involve an unknown number of auditory and non-auditory networks and molecular pathways. This complex combination has hampered advancements in the field. The identification of specific genetic factors has been at the forefront of several research investigations in the past decade...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28463191/quantifying-backscatter-anisotropy-using-the-reference-phantom-method
#3
Quinton W Guerrero, Ivan Rosado-Mendez, Lindsey C Drehfal, Helen Feltovich, Timothy J Hall
Acoustic properties can be exploited to infer and evaluate tissue microstructure. However, common assumptions are that the medium of interest is homogeneous and isotropic, and that its underlying physical properties cause diffuse scattering. In this paper, we describe how we developed and tested novel parameters designed to address isotropy/anisotropy in backscattered echo signal power in complex biological tissues. Specifically, we explored isotropy/anisotropy in backscattered power in isotropic phantoms (spherical glass beads), an anisotropic phantom (dialysis phantom with rod-like fibers), and an in vivo human tissue with well-described anisotropy (bicep muscle)...
April 27, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28450032/broadband-acoustic-measurement-of-an-agar-based-tissue-mimicking-material-a-longitudinal-study
#4
Adela Rabell Montiel, Jacinta E Browne, Stephen D Pye, Tom A Anderson, Carmel M Moran
Commercially available ultrasound quality assurance test phantoms rely on the long-term acoustic stability of the tissue-mimicking-material (TMM). Measurement of the acoustic properties of the TMM can be technically challenging, and it is important to ensure its stability. The standard technique is to film-wrap samples of TMM and to measure the acoustic properties in a water bath. In this study, a modified technique was proposed whereby the samples of TMM are measured in a preserving fluid that is intended to maintain their characteristics...
April 24, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28418323/the-personality-profile-of-tinnitus-sufferers-and-a-nontinnitus-control-group
#5
Mithila Durai, Mary G O'Keeffe, Grant D Searchfield
BACKGROUND: Chronic tinnitus (phantom perception of sound) significantly disrupts quality of life in 15-20% of those who experience it. Understanding how certain personality traits impact tinnitus perception and distress can be beneficial for the development of interventions to improve the lives of tinnitus sufferers. PURPOSE: Four key self-reported personality traits (social closeness, stress reaction, alienation, and self-control) were identified from previous research as being associated with tinnitus...
April 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28415122/p1138cardiac-shear-wave-velocity-in-healthy-individuals
#6
M Strachinaru, M L Geleijnse, J G Bosch, N De Jong, Afw Van Der Steen, B M Van Dalen, H J Vos
Background: The closure of the valves generates shear waves in the heart walls. The propagation velocity of shear waves relates to stiffness. This could potentially be used to estimate the stiffness of the myocardium, with huge potential implications in pathologies characterized by a deterioration of the diastolic properties of the left ventricle. In an earlier phantom study we already validated shear wave tracking with a clinical ultrasound system in cardiac mode. Purpose: In this study we aimed to measure the shear waves velocity in normal individuals...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28386578/large-field-of-view-optical-elastography-using-digital-image-correlation-for-biological-soft-tissue-investigation
#7
Daniel Claus, Marijo Mlikota, Jonathan Geibel, Thomas Reichenbach, Giancarlo Pedrini, Johannes Mischinger, Siegfried Schmauder, Wolfgang Osten
In minimally invasive surgery the haptic feedback, which represents an important tool for the localization of abnormalities, is no longer available. Elastography is an imaging technique that results in quantitative elastic parameters. It can hence be used to replace the lost sense of touch, as to enable tissue localization and discrimination. Digital image correlation is the chosen elastographic imaging technique. The implementation discussed here is clinically sound, based on a spectrally engineered illumination source that enables imaging of biological surface markers (blood vessels) with high contrast...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28384210/thermal-characteristics-of-non-biological-vessel-phantoms-for-treatment-of-varicose-veins-using-high-intensity-focused-ultrasound
#8
Mi-Sun Kim, Ju-Young Kim, Si-Cheol Noh, Heung-Ho Choi
The ultrasonic treatment of varicose veins uses high-intensity focused ultrasound, in which a blood vessel is contracted by converting acoustic energy into thermal energy. In this study, we propose a phantom of varicose veins that can be applied for the efficient evaluation of ultrasonic treatment in varicose veins. The proposed phantom consisted of glycerol base tissue equivalent material, vessel mimic tube, and blood mimic substances. The vessel mimic tube was placed inner glycerol phantom and it was filled with blood mimic substances...
2017: PloS One
https://www.readbyqxmd.com/read/28372078/time-domain-reconstruction-of-sound-speed-and-attenuation-in-ultrasound-computed-tomography-using-full-wave-inversion
#9
M Pérez-Liva, J L Herraiz, J M Udías, E Miller, B T Cox, B E Treeby
Ultrasound computed tomography (USCT) is a non-invasive imaging technique that provides information about the acoustic properties of soft tissues in the body, such as the speed of sound (SS) and acoustic attenuation (AA). Knowledge of these properties can improve the discrimination between benign and malignant masses, especially in breast cancer studies. Full wave inversion (FWI) methods for image reconstruction in USCT provide the best image quality compared to more approximate methods. Using FWI, the SS is usually recovered in the time domain, and the AA is usually recovered in the frequency domain...
March 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28303087/a-pilot-genome-wide-association-study-identifies-potential-metabolic-pathways-involved-in-tinnitus
#10
Annick Gilles, Guy Van Camp, Paul Van de Heyning, Erik Fransen
Tinnitus, the perception of an auditory phantom sound in the form of ringing, buzzing, roaring, or hissing in the absence of an external sound source, is perceived by ~15% of the population and 2.5% experiences a severely bothersome tinnitus. The contribution of genes on the development of tinnitus is still under debate. The current manuscript reports a pilot Genome Wide Association Study (GWAS) into tinnitus, in a small cohort of 167 independent tinnitus subjects, and 749 non-tinnitus controls, who were collected as part of a cross-sectional study...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28287955/accurate-3-d-profile-extraction-of-skull-bone-using-an-ultrasound-matrix-array
#11
Mehdi Hajian, Robert Gaspar, Roman Maev
The present study investigates the feasibility, accuracy, and precision of 3-D profile extraction of the human skull bone using a custom-designed ultrasound matrix transducer in Pulse-Echo. Due to the attenuative scattering properties of the skull, the backscattered echoes from the inner surface of the skull are severely degraded, attenuated, and at some points overlapped. Furthermore, the speed of sound (SOS) in the skull varies significantly in different zones and also from case to case; if considered constant, it introduces significant error to the profile measurement...
March 8, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28260394/evidence-for-behaviorally-segregated-spatiotemporally-overlapping-subnetworks-in-phantom-sound-perception
#12
Anusha Mohan, Nicole Moreno, Jae-Jin Song, Dirk De Ridder, Sven Vanneste
One of the most intriguing questions in neuroscience is to understand the mechanism of information transfer between different brain areas. Recently, network theory has gained traction and is at the forefront of providing a possible explanation to not only the mechanism of information transfer but also in the identification of different neuropathologies. The perception of a phantom ringing in the ear called tinnitus, similar to other neuropathologies, has been shown to be accompanied by aberrant functional connectivity between different brain areas...
April 2017: Brain Connectivity
https://www.readbyqxmd.com/read/28253670/in-vivo-ultrasonic-attenuation-in-cetacean-soft-tissues
#13
Michael D Gray, Peter H Rogers
In vivo ultrasonic attenuation was estimated for extracranial soft tissues of two Tursiops truncatus and one Delphinapterus leucas. Backscatter data was non-invasively collected as part of routine health-based ultrasound examinations using a transducer operating in the 1.6-3.7 MHz frequency range. Data collected over the proximal mandible and temporal regions was processed to yield attenuation estimates using a reference tissue phantom whose properties had been independently determined. The estimated attenuations were at the low end of the range of literature-reported values for mammalian fatty and connective tissues...
February 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28225357/robust-sound-speed-estimation-for-ultrasound-based-hepatic-steatosis-assessment
#14
Marion Imbault, Alex Faccinetto, Bruno-Félix Osmanski, Antoine Tissier, Thomas Deffieux, Jean-Luc Gennisson, Valérie Vilgrain, Mickaël Tanter
Hepatic steatosis is a common condition, the prevalence of which is increasing along with non-alcoholic fatty liver disease (NAFLD). Currently, the most accurate noninvasive imaging method for diagnosing and quantifying hepatic steatosis is MRI, which estimates the proton-density fat fraction (PDFF) as a measure of fractional fat content. However, MRI suffers several limitations including cost, contra-indications and poor availability. Although conventional ultrasound is widely used by radiologists for hepatic steatosis assessment, it remains qualitative and operator dependent...
February 22, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28192822/-tinnitus-clinical-symptoms-and-therapy
#15
Birgit Mazurek, Agnieszka J Szczepek, Petra Brüggemann
Tinnitus is a phantom sound that can be a symptom of various disorders such as hearing loss, cardiovascular diseases, neurological disorders, diabetes or tumors. Because of the inability to divert the auditory attention from tinnitus sound, patients suffer with insomnia, problems with concentration and other psychological conditions, in some extreme cases including major depression symptoms. The auditory character of tinnitus induces the patients to seek help predominantly at the otolaryngologist practice. The first aim of a physician is to establish the cause of tinnitus and to measure its audiological properties...
January 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28174532/resting-state-brain-abnormalities-in-chronic-subjective-tinnitus-a-meta-analysis
#16
Yu-Chen Chen, Fang Wang, Jie Wang, Fan Bo, Wenqing Xia, Jian-Ping Gu, Xindao Yin
Purpose: The neural mechanisms that give rise to the phantom sound of tinnitus have not been fully elucidated. Neuroimaging studies have revealed abnormalities in resting-state activity that could represent the neural signature of tinnitus, but there is considerable heterogeneity in the data. To address this issue, we conducted a meta-analysis of published neuroimaging studies aimed at identifying a common core of resting-state brain abnormalities in tinnitus patients. Methods: A systematic search was conducted for whole-brain resting-state neuroimaging studies with SPECT, PET and functional MRI that compared chronic tinnitus patients with healthy controls...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28165334/sensitivity-of-simulated-transcranial-ultrasound-fields-to-acoustic-medium-property-maps
#17
James Robertson, Eleanor Martin, Ben Cox, Bradley E Treeby
High intensity transcranial focused ultrasound is an FDA approved treatment for essential tremor, while low-intensity applications such as neurostimulation and opening the blood brain barrier are under active research. Simulations of transcranial ultrasound propagation are used both for focusing through the skull, and predicting intracranial fields. Maps of the skull acoustic properties are necessary for accurate simulations, and can be derived from medical images using a variety of methods. The skull maps range from segmented, homogeneous models, to fully heterogeneous models derived from medical image intensity...
April 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28160746/selective-attentional-impairment-in-chronic-tinnitus-evidence-from-an-event-related-potentials-study
#18
Daniela Mannarelli, Caterina Pauletti, Patrizia Mancini, Alessandra Fioretti, Antonio Greco, Marco De Vincentiis, Francesco Fattapposta
OBJECTIVE: Tinnitus is an auditory phantom sensation experienced in the absence of a sound source. Cognitive dysfunctions, especially in working memory and attention, are frequently reported to be associated with tinnitus. The aim of this study was to investigate attentional functioning in a group of subjects with chronic tinnitus using ERPs, and in particular the P300 components. METHODS: We studied 20 patients with chronic tinnitus and 20 healthy subjects that performed a P300 Novelty task...
March 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28112466/tinnitus-distress-is-linked-to-enhanced-resting-state-functional-connectivity-from-the-limbic-system-to-the-auditory-cortex
#19
Yu-Chen Chen, Wenqing Xia, Huiyou Chen, Yuan Feng, Jin-Jing Xu, Jian-Ping Gu, Richard Salvi, Xindao Yin
The phantom sound of tinnitus is believed to be triggered by aberrant neural activity in the central auditory pathway, but since this debilitating condition is often associated with emotional distress and anxiety, these comorbidities likely arise from maladaptive functional connections to limbic structures such as the amygdala and hippocampus. To test this hypothesis, resting-state functional magnetic resonance imaging (fMRI) was used to identify aberrant effective connectivity of the amygdala and hippocampus in tinnitus patients and to determine the relationship with tinnitus characteristics...
January 23, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28072813/a-case-report-on-red-ear-syndrome-with-tinnitus-successfully-treated-with-transcranial-random-noise-stimulation
#20
Peter M Kreuzer, Veronika Vielsmeier, Timm B Poeppl, Berthold Langguth
BACKGROUND: The red ear syndrome represents a rare symptom complex consisting of auricular erythema associated with painful and burning sensations. It has been described in combination with tinnitus rarely. It has been hypothesized to be etiologically related to altered trigeminal afferent input, temporomandibular disorders, and thalamic dysfunction. OBJECTIVES: The initial objective of applying transcranial random noise stimulation (tRNS) in a case of red ear syndrome in combination with tinnitus was the alleviation of the phantom sounds...
January 2017: Pain Physician
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