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https://www.readbyqxmd.com/read/27919835/bariatric-surgery-is-associated-with-less-progression-of-diabetic-retinopathy-a-systematic-review-and-meta-analysis
#1
REVIEW
Yong Joon Kim, Byoung Hyuck Kim, Bo Mi Choi, Hae Jung Sun, Sung Jin Lee, Kyung Seek Choi
BACKGROUND: The impact of bariatric surgery on diabetic retinopathy (DR) remains underexplored, and conflicting results have been reported. OBJECTIVE: To clarify the impact of bariatric surgery on DR. SETTING: A systematic review and meta-analysis. University Hospital, Korea. METHODS: A comprehensive database search was performed across PubMed, Embase, Web of Science, and the Cochrane Library from inception to August 2016...
October 5, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27919281/incidence-causes-and-consequences-of-preventable-adverse-drug-events-protocol-for-an-overview-of-reviews
#2
Brian Hutton, Salmaan Kanji, Erika McDonald, Fatemeh Yazdi, Dianna Wolfe, Kednapa Thavorn, Sally Pepper, Laurie Chapman, Becky Skidmore, David Moher
BACKGROUND: Medication errors represent a noteworthy source of harm to patients. In recent years, several systematic reviews have assessed the frequency and causes of these events, as well as other factors such as commonly associated drugs, their incidence in different specialties, and their consequences to patients. Despite this past literature, there remains a need to study discrepancies between these reviews and establish the current state of the evidence. The planned review will bring together, compare, and contract existing evidence related to the occurrence of medication errors in acute and continuing/long-term care settings...
December 5, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27918269/prevention-of-hospital-acquired-bloodstream-infections-through-chlorhexidine-gluconate-impregnated-washcloth-bathing-in-intensive-care-units-a-systematic-review-and-meta-analysis-of-randomised-crossover-trials
#3
Elsa Afonso, Koen Blot, Stijn Blot
We assessed the impact of 2% daily patient bathing with chlorhexidine gluconate (CHG) washcloths on the incidence of hospital-acquired (HA) and central line-associated (CLA) bloodstream infections (BSI) in intensive care units (ICUs). We searched randomised studies in Medline, EMBASE, Cochrane Library (CENTRAL) and Web of Science databases up to April 2015. Primary outcomes were total HABSI, central line, and non-central line-associated BSI rates per patient-days. Secondary outcomes included Gram-negative and Gram-positive BSI rates and adverse events...
November 17, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27911277/gstm1-and-gstt1-polymorphisms-are-associated-with-increased-bladder-cancer-risk-evidence-from-updated-meta-analysis
#4
Cui Yu, Chen Hequn, Liu Longfei, Wang Long, Chen Zhi, Zeng Feng, Chen Jinbo, Li Chao, Zu Xiongbing
BACKGROUND: Previous studies have indicated association between GSTM1 and GSTT1 gene polymorphisms and bladder cancer susceptibility, but the results have been inconclusive. Here, we performed a meta-analysis to investigate the association between GSTM1/GSTT1 deletion polymorphisms and bladder cancer susceptibility. METHODS: We searched for all studies investigating the association between GSTM1 or GSTT1 polymorphism and bladder cancer susceptibility in Pubmed, Web of Knowledge, and the Cochrane Central Search Library...
November 29, 2016: Oncotarget
https://www.readbyqxmd.com/read/27906934/can-unilateral-kyphoplasty-replace-bilateral-kyphoplasty-in-treatment-of-osteoporotic-vertebral-compression-fractures-a-systematic-review-and-meta-analysis
#5
Han Sun, Pei-Pei Lu, Yi-Jie Liu, Xu Yang, Ping-Hui Zhou, Xiao-Feng Shen, Si-Wei Sun, Huilin Yang
BACKGROUND: Kyphoplasty has been proven to be an efficient method to relieve patient suffering from osteoporotic vertebral compression fractures (OVCFs). Because of its technological superiority, unilateral kyphoplasty consumes less operative time and bone cement than traditional bilateral kyphoplasty. However, there is controversy about which method is most efficient in the treatment of OVCFs. Thus, an overall analysis should be performed to shed light on the facts corroborating both procedures...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27905696/the-curative-effect-of-early-use-of-enteral-immunonutrition-in-postoperative-gastric-cancer-a-meta-analysis
#6
Hu Qiang, Lu Hang, Sun Y Shui
INTRODUCTION: It's uncertain about the clinical efficacy which early enteral immunonutrition in postoperative gastric cancer patients,and this study attempts to assess its clinical efficacy. EVIDENCE ACQUISITION: Use the search engine database incuding the Pubmed,the Cochrane library, Web of Science, Medline,and Embase,which there are comparative studies of early efficacy of enteral immune nutrition and standard enteral nutrition after gastric cancer operation.According to the studies,we use the RevMan 5...
December 1, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27901277/negative-pressure-wound-therapy-for-prevention-and-treatment-of-surgical-site-infections-after-vascular-surgery
#7
REVIEW
S Acosta, M Björck, A Wanhainen
BACKGROUND: Indications for negative-pressure wound therapy (NPWT) in vascular surgical patients are expanding. The aim of this review was to outline the evidence for NPWT on open and closed wounds. METHODS: A PubMed, EMBASE and Cochrane Library search from 2007 to June 2016 was performed combining the medical subject headings terms 'wound infection', 'abdominal aortic aneurysm (AAA)', 'fasciotomy', 'vascular surgery' and 'NPWT' or 'VAC'. RESULTS: NPWT of open infected groin wounds was associated with shorter duration of wound healing by 47 days, and was more cost-effective than alginate dressings in one RCT...
November 30, 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27901247/anabolic-steroids-for-rehabilitation-after-hip-fracture-in-older-people
#8
Vaqas Farooqi, Maayken E L van den Berg, Ian D Cameron, Maria Crotty
BACKGROUND: Hip fracture occurs predominantly in older people, many of whom are frail and undernourished. After hip fracture surgery and rehabilitation, most patients experience a decline in mobility and function. Anabolic steroids, the synthetic derivatives of the male hormone testosterone, have been used in combination with exercise to improve muscle mass and strength in athletes. They may have similar effects in older people who are recovering from hip fracture. OBJECTIVES: To examine the effects (primarily in terms of functional outcome and adverse events) of anabolic steroids after surgical treatment of hip fracture in older people...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27897967/an-observational-study-of-donor-ex-vivo-lung-perfusion-in-uk-lung-transplantation-develop-uk
#9
Andrew Fisher, Anders Andreasson, Alexandros Chrysos, Joanne Lally, Chrysovalanto Mamasoula, Catherine Exley, Jennifer Wilkinson, Jessica Qian, Gillian Watson, Oli Lewington, Thomas Chadwick, Elaine McColl, Mark Pearce, Kay Mann, Nicola McMeekin, Luke Vale, Steven Tsui, Nizar Yonan, Andre Simon, Nandor Marczin, Jorge Mascaro, John Dark
BACKGROUND: Many patients awaiting lung transplantation die before a donor organ becomes available. Ex vivo lung perfusion (EVLP) allows initially unusable donor lungs to be assessed and reconditioned for clinical use. OBJECTIVE: The objective of the Donor Ex Vivo Lung Perfusion in UK lung transplantation study was to evaluate the clinical effectiveness and cost-effectiveness of EVLP in increasing UK lung transplant activity. DESIGN: A multicentre, unblinded, non-randomised, non-inferiority observational study to compare transplant outcomes between EVLP-assessed and standard donor lungs...
November 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27891666/a-systematic-review-of-the-outcomes-reported-in-trials-of-medication-review-in-older-patients-the-need-for-a-core-outcome-set
#10
Jean-Baptiste Beuscart, Lisa G Pont, Stefanie Thevelin, Benoit Boland, Olivia Dalleur, Anne Rutjes, Johanna I Westbrook, Anne Spinewine
AIM: Medication review has been advocated as one of the measures to tackle the challenge of polypharmacy in older patients, yet there is no consensus on how best to evaluate its efficacy. This study aimed to assess outcome reporting in trials of medication review in older patients. METHODS: Randomized controlled trials (RCTs), prospective studies and RCT protocols involving medication review performed in patients aged 65 years or older in any setting of care were identified from: (1) a recent systematic review; (2) RCT registries of ongoing studies; (3) the Cochrane library...
November 27, 2016: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27890352/residential-aged-care-medication-review-to-improve-the-quality-of%C3%A2-medication-use-a-systematic-review
#11
REVIEW
Kaeshaelya Thiruchelvam, Syed Shahzad Hasan, Pei Se Wong, Therese Kairuz
BACKGROUND: Aging is often associated with various underlying comorbidities that warrant the use of multiple medications. Various interventions, including medication reviews, to optimize pharmacotherapy in older people residing in aged care facilities have been described and evaluated. Previous systematic reviews support the positive impact of various medication-related interventions but are not conclusive because of several factors. OBJECTIVES: The current study aimed to assess the impact of medication reviews in aged care facilities, with additional focus on the types of medication reviews, using randomized controlled trials (RCTs) and observational studies...
November 24, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27888996/the-effects-of-chronic-obstructive-pulmonary-disease-self-management-interventions-on-improvement-of-quality-of-life-in-copd-patients-a-meta-analysis
#12
REVIEW
Danielle Cannon, Nicholas Buys, Krishna Bajee Sriram, Siddharth Sharma, Norman Morris, Jing Sun
This article aimed to analyse the outcome of self-management randomised control trials and their impact upon chronic obstructive pulmonary disease patients' health outcomes using meta-analysis approach. PubMed, Scopus, CINAHL, Web of Science databases and Cochrane Library, were searched for articles between 1990 and December 2015 by two researchers. Self-management programs significantly improved patients' quality of life across all domains of the St George Respiratory Questionnaire (SGRQ) (activity -2.21 (95% CI: -3...
December 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27886990/radiation-protection-studies-for-medical-particle-accelerators-using-fluka-monte-carlo-code
#13
Angelo Infantino, Gianfranco Cicoria, Giulia Lucconi, Davide Pancaldi, Sara Vichi, Federico Zagni, Domiziano Mostacci, Mario Marengo
Radiation protection (RP) in the use of medical cyclotrons involves many aspects both in the routine use and for the decommissioning of a site. Guidelines for site planning and installation, as well as for RP assessment, are given in international documents; however, the latter typically offer analytic methods of calculation of shielding and materials activation, in approximate or idealised geometry set-ups. The availability of Monte Carlo (MC) codes with accurate up-to-date libraries for transport and interaction of neutrons and charged particles at energies below 250 MeV, together with the continuously increasing power of modern computers, makes the systematic use of simulations with realistic geometries possible, yielding equipment and site-specific evaluation of the source terms, shielding requirements and all quantities relevant to RP at the same time...
November 24, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27875320/association-of-chronic-hepatitis-b-virus-infection-with-preterm-birth-our-experience-and-meta-analysis
#14
Ai-Min Cui, Jian-Guo Shao, Hai-Bo Li, Yi Shen, Zhi-Xian Chen, Sheng Zhang, Zhao-Lian Bian, Gang Qin, Xiao-Yan Cheng
OBJECTIVES: To assess the association of chronic hepatitis B virus (HBV) infection with preterm birth (PTB). METHODS: A cohort of 20,498 pregnant women (497 HBV carriers with 20,001 non-HBV controls) with normal alanine aminotransferase (ALT) levels was selected from the Obstetrics & Gynecology Hospital of Nantong University. The clinical parameters and PTB incidence were compared between HBV carriers and non-HBV subjects. For the meta-analysis, we searched the PubMed, Ovid and Cochrane Library databases for studies comparing PTB incidence between individuals with chronic HBV infection and non-HBV subjects...
November 22, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27875033/comparison-of-preoperative-hair-removal-methods-for-the-reduction-of-surgical-site-infections-a-meta-analysis
#15
REVIEW
Dingmei Shi, Yao Yao, Weifei Yu
AIMS AND OBJECTIVES: To evaluate the efficacy of different methods of preoperative hair removal in reducing surgical site infections (SSIs). BACKGROUND: Surgical site infections (SSIs) are a major source of morbidity and prolonged hospitalization following surgery. However, there is a lack of data regarding the impact of different preoperative hair removal techniques on the incidence of SSIs. DESIGN: A systematic literature review and meta-analysis...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27872113/does-integrated-care-reduce-hospital-activity-for-patients-with-chronic-diseases-an-umbrella-review-of-systematic-reviews
#16
Sarah Damery, Sarah Flanagan, Gill Combes
OBJECTIVE: To summarise the evidence regarding the effectiveness of integrated care interventions in reducing hospital activity. DESIGN: Umbrella review of systematic reviews and meta-analyses. SETTING: Interventions must have delivered care crossing the boundary between at least two health and/or social care settings. PARTICIPANTS: Adult patients with one or more chronic diseases. DATA SOURCES: MEDLINE, Embase, ASSIA, PsycINFO, HMIC, CINAHL, Cochrane Library (HTA database, DARE, Cochrane Database of Systematic Reviews), EPPI-Centre, TRIP, HEED, manual screening of references...
November 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27871803/abdominal-drainage-versus-no-abdominal-drainage-for-laparoscopic-cholecystectomy-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#17
REVIEW
Lv Yong, Bai Guang
The aim is to assess the benefits and harms of routine abdominal drainage in laparoscopic cholecystectomy. We searched the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library, MEDLINE, EMBASE, and Science Citation Index Expanded until August 2016. We included all randomised clinical trials comparing drainage versus no drainage after laparoscopic cholecystectomy irrespective of language and publication status. We used standard methodological procedures in accordance with the PRISMA guidelines...
November 15, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27871573/the-preoperative-use-of-field-tests-of-exercise-tolerance-to-predict-postoperative-outcome-in-intra-abdominal-surgery-a-systematic-review
#18
REVIEW
Jonathan Moran, Fiona Wilson, Emer Guinan, Paul McCormick, Juliette Hussey, Jeanne Moriarty
STUDY OBJECTIVE: To assess the ability of field tests of exercise tolerance, such as the 6-minute walk test (6MWT) and incremental shuttle walk test (ISWT), to predict postoperative outcome following intra-abdominal surgery. DESIGN: A systematic review. SETTING: A hospital-affiliated university. MEASUREMENTS: The following databases were searched: AMED, CINAHL, EMBASE, PEDro, PubMed/MEDLINE, and The Cochrane Library...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27871539/liberal-or-restrictive-fluid-management-during-elective-surgery-a-systematic-review-and-meta-analysis
#19
REVIEW
Pim B B Schol, Ivon M Terink, Marcus D Lancé, Hubertina C J Scheepers
This article reviews if a restrictive fluid management policy reduces the complication rate if compared to liberal fluid management policy during elective surgery. The PubMed database was explored by 2 independent researchers. We used the following search terms: "Blood transfusion (MESH); transfusion need; fluid therapy (MESH); permissive hypotension; fluid management; resuscitation; restrictive fluid management; liberal fluid management; elective surgery; damage control resuscitation; surgical procedures, operative (MESH); wounds (MESH); injuries (MESH); surgery; trauma patients...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27871504/efficacy-and-safety-of-sugammadex-compared-to-neostigmine-for-reversal-of-neuromuscular-blockade-a-meta-analysis-of-randomized-controlled-trials
#20
REVIEW
Michele Carron, Francesco Zarantonello, Paola Tellaroli, Carlo Ori
BACKGROUND AND OBJECTIVE: Sugammadex has been introduced for reversal of rocuronium (or vecuronium)-induced neuromuscular blockade (NMB). Although its efficacy has been established, data are conflicting whether it is safer than neostigmine traditionally used for reversing NMB. DESIGN: Meta-analysis of data about effectiveness and safety of sugammadex compared to neostigmine for reversing NMB in adults was performed using the PRISMA methodology. SETTING: University medical hospital...
December 2016: Journal of Clinical Anesthesia
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