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https://www.readbyqxmd.com/read/29773920/effects-of-emergent-literacy-interventions-for-preschoolers-with-autism-spectrum-disorder
#1
Roxanne F Hudson, Elizabeth A Sanders, Rosanne Greenway, Sharon Xie, Maya Smith, Colin Gasamis, Jay Martini, Ilene Schwartz, Jacob Hackett
Combining data from a series of three planned, consecutive independent randomized controlled trials (RCTs), the present study investigates two literacy interventions for preschool children with autism spectrum disorder (ASD). For the first cohort, children were randomized to interactive book reading treatment (IBR)or a business-as-usual (BAU) control condition; in Cohort 2, children were randomized to phonological awareness treatment (PA)or BAU; in Cohort 3, children were randomized to IBR or PA. Both treatments were implemented weekly in the classroom from November to May...
October 2017: Exceptional Children
https://www.readbyqxmd.com/read/29773825/consistent-prediction-of-go-protein-localization
#2
Flavio E Spetale, Debora Arce, Flavia Krsticevic, Pilar Bulacio, Elizabeth Tapia
The GO-Cellular Component (GO-CC) ontology provides a controlled vocabulary for the consistent description of the subcellular compartments or macromolecular complexes where proteins may act. Current machine learning-based methods used for the automated GO-CC annotation of proteins suffer from the inconsistency of individual GO-CC term predictions. Here, we present FGGA-CC+ , a class of hierarchical graph-based classifiers for the consistent GO-CC annotation of protein coding genes at the subcellular compartment or macromolecular complex levels...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29758388/second-language-learners-who-are-at-risk-for-reading-disabilities-a-growth-mixture-model-study
#3
Susanna S Yeung
This one-year longitudinal study examined the developmental trajectories of English reading in Chinese children learning English as a second language (ESL) and identified cognitive profiles of children who are at risk for English reading disability. One hundred and eighty-four Chinese ESL children from eight Hong Kong kindergartens were measured four times during their last year of kindergarten for phonological awareness, letter knowledge, vocabulary and English word reading. Growth mixture modeling was applied to classify the children based on their growth trajectories in English word reading...
May 11, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29756802/is-subjective-memory-specific-for-memory-performance-or-general-across-cognitive-domains-findings-from-the-seattle-longitudinal-study
#4
Gizem Hülür, Sherry L Willis, Christopher Hertzog, K Warner Schaie, Denis Gerstorf
A growing body of research has examined whether people's judgments of their own memory functioning accurately reflect their memory performance at cross-section and over time. Relatively less is known about whether these judgments are specifically based on memory performance, or reflect general cognitive change. The aim of the present study was to examine longitudinal associations of subjective memory with performance in tests of episodic memory and a wide range of other cognitive tests, including the Wechsler Adult Intelligence Scale-Revised (WAIS-R) Block Design, Comprehension, Digit Span, Digit Symbol, and Vocabulary subtests...
May 2018: Psychology and Aging
https://www.readbyqxmd.com/read/29754832/ondansetron-in-pregnancy-and-the-risk-of-congenital-malformations-a-systematic-review
#5
Melissa Lavecchia, Radha Chari, Sandra Campbell, Sue Ross
OBJECTIVE: Ondansetron, not approved for use in pregnancy, is increasingly being prescribed for nausea and vomiting in pregnancy and hyperemesis gravidarum. A number of recent lawsuits have highlighted the possibility that ondansetron may cause congenital malformations. The aim of this study was to systematically review epidemiological evidence on the potential association of prenatal exposure to ondansetron and congenital malformations. METHODS: Systematic searches in Medline and Embase were performed in June 2017 using controlled vocabulary and key words, and references of search results were reviewed...
May 10, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29753216/false-belief-and-relative-clauses-in-autism-spectrum-disorders
#6
Stephanie Durrleman, Wolfram Hinzen, Julie Franck
Previous studies have suggested sentential complementation is the crucial ingredient of language that relates to false-belief (FB) reasoning, while the role of relative clauses (RCs) is less clear. Nevertheless, under the hypothesis that clausal embedding has a meta-representational effect, arguably implied in FB, one expects a link between FB and not only complementation but also relativization. Seventeen children with ASD (6 to 16 years, mean age 9;2) were assessed for RCs and FB. Comprehension of RCs significantly predicted FB performance, while none of the controlled factors played a predictive role (comprehension of simple sentences, vocabulary, morpho-syntax and working memory)...
April 17, 2018: Journal of Communication Disorders
https://www.readbyqxmd.com/read/29731212/no-292-abnormal-uterine-bleeding-in-pre-menopausal-women
#7
Sukhbir Singh, Carolyn Best, Sheila Dunn, Nicholas Leyland, Wendy Lynn Wolfman
BACKGROUND: Abnormal uterine bleeding is the direct cause of a significant health care burden for women, their families, and society as a whole. Up to 30% of women will seek medical assistance for this problem during their reproductive years. This guideline replaces previous clinical guidelines on the topic and is aimed to enable health care providers with the tools to provide the latest evidence-based care in the diagnosis and the medical and surgical management of this common problem...
May 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29731210/no-249-asymptomatic-endometrial-thickening
#8
Wendy Wolfman
OBJECTIVE: To formulate clinical recommendations for the assessment of endometrial thickening when it is found on ultrasound in a postmenopausal patient without bleeding. OUTCOMES: Ensure that women with asymptomatic thickening and endometrial polyps found on ultrasound are managed appropriately. EVIDENCE: Published literature was retrieved through searches of English language articles from the EMBASE, Cochrane, and PubMed databases for relevant peer-reviewed articles dating from 1970 to 2009, using appropriate controlled vocabulary (e...
May 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29730573/language-balance-and-switching-ability-in-children-acquiring-english-as-a-second-language
#9
Claire Goriot, Mirjam Broersma, James M McQueen, Sharon Unsworth, Roeland van Hout
This study investigated whether relative lexical proficiency in Dutch and English in child second language (L2) learners is related to executive functioning. Participants were Dutch primary school pupils of three different age groups (4-5, 8-9, and 11-12 years) who either were enrolled in an early-English schooling program or were age-matched controls not on that early-English program. Participants performed tasks that measured switching, inhibition, and working memory. Early-English program pupils had greater knowledge of English vocabulary and more balanced Dutch-English lexicons...
May 3, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29730448/a-big-data-approach-to-the-concordance-of-the-toxicity-of-pharmaceuticals-in-animals-and-humans
#10
Matthew Clark
Although lack of efficacy is an important cause of late stage attrition in drug development the shortcomings in the translation of toxicities observed during the preclinical development to observations in clinical trials or post-approval is an ongoing topic of research. The concordance between preclinical and clinical safety observations has been analyzed only on relatively small data sets, mostly over short time periods of drug approvals. We therefore explored the feasibility of a big-data analysis on a set of 3290 approved drugs and formulations for which 1,637,449 adverse events were reported for both humans animal species in regulatory submissions over a period of more than 70 years...
May 3, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29723069/prosodic-and-segmental-aspects-of-nonword-repetition-in-4-to-6-year-old-children-who-are-deaf-and-hard-of-hearing-compared-to-controls-with-normal-hearing
#11
Simon Sundström, Ulrika Löfkvist, Björn Lyxell, Christina Samuelsson
Children who are deaf or hard of hearing (DHH) are at an increased risk of speech and language deficits. Nonword repetition (NWR) is a potential predictor of problems with phonology, grammar and lexicon in DHH children. The aim of the present study was to examine repetition of prosodic features and segments in nonwords by DHH children compared to children with normal hearing (NH) and to relate NWR performance to measures of language ability and background variables. In this cross-sectional study, 14 Swedish-speaking children with mild-profound sensorineural hearing loss, aged 4-6 years, and 29 age-matched controls with NH and typical language development participated...
May 3, 2018: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/29708182/neurologist-patient-communication-about-epilepsy-in-the-united-states-spain-and-germany
#12
John M Stern, Fernando Cendes, Frank Gilliam, Patrick Kwan, Philippe Ryvlin, Joseph Sirven, Brien Smith, Aleksandra Adomas, Lauren Walter
Background: Effective communication between patients and their health care providers is recognized as critically important to improve the quality of health services for individuals with epilepsy. We aimed to describe in-office neurologist-patient conversations about epilepsy and focus on disease identification, shared decision-making, and care planning. Methods: Transcripts and audio recordings of conversations between patients and neurologists in the United States, Spain, and Germany were analyzed linguistically in the topic areas of epilepsy identification and diagnosis, disease education, treatments, and care planning...
April 2018: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/29707196/improving-communication-for-interdisciplinary-teams-working-on-storage-of-digital-information-in-dna
#13
Emily E Hesketh, Jossy Sayir, Nick Goldman
Close collaboration between specialists from diverse backgrounds and working in different scientific domains is an effective strategy to overcome challenges in areas that interface between biology, chemistry, physics and engineering. Communication in such collaborations can itself be challenging.  Even when projects are successfully concluded, resulting publications - necessarily multi-authored - have the potential to be disjointed. Few, both in the field and outside, may be able to fully understand the work as a whole...
2018: F1000Research
https://www.readbyqxmd.com/read/29706915/the-impact-of-morphological-awareness-on-word-reading-and-dictation-in-chinese-early-adolescent-readers-with-and-without-dyslexia
#14
Sylvia Chanda Kalindi, Kevin Kien Hoa Chung
This study investigated the role of morphological awareness in understanding Chinese word reading and dictation among Chinese-speaking adolescent readers in Hong Kong as well as the cognitive-linguistic profile of early adolescent readers with dyslexia. Fifty-four readers with dyslexia in Grades 5 and 6 were compared with 54 chronological age-matched (CA) typical readers on the following measures of cognitive-linguistic and literacy skills: morphological awareness, phonological awareness, visual-orthographic knowledge, rapid naming, vocabulary knowledge, verbal short-term memory (STM), Chinese word reading, and dictation (or spelling)...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29703802/a-multicomponent-early-intervention-program-and-trajectories-of-behavior-cognition-and-health
#15
Sylvana M Côté, Massimiliano Orri, Richard E Tremblay, Orla Doyle
OBJECTIVES: To investigate the developmental impact of a prenatal-to-age-5 multicomponent early intervention program targeting families living in low socioeconomic conditions. METHODS: Pregnant women from a disadvantaged Irish community were randomly assigned into a treatment group (home visits, baby massage, and parenting program; n = 115) or control group ( n = 118). Children's behavioral problems (externalizing, internalizing), cognitive skills (general, vocabulary), and health service use (number of health clinic visits), were regularly assessed (6 months to 4 years of age)...
April 27, 2018: Pediatrics
https://www.readbyqxmd.com/read/29702378/emergent-literacy-in-print-and-electronic-contexts-the-influence-of-book-type-narration-source-and-attention
#16
Kathryn J O'Toole, Kathleen N Kannass
Young children learn from traditional print books, but there has been no direct comparison of their learning from print books and tablet e-books while controlling for narration source. The current project used a between-subjects design and examined how 4-year-olds (N = 100) learned words and story content from a print book read aloud by a live adult, a print book narrated by an audio device, an e-book read aloud by a live adult, and an e-book narrated by an audio device. Attention to the book and prior experience with tablet e-books were also measured and included in analyses...
April 24, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29697012/heart-rate-variability-in-patients-with-systemic-lupus-erythematosus-a-systematic-review-and-methodological-considerations
#17
P S Matusik, P T Matusik, P K Stein
Aim The aim of this review was to summarize current knowledge about the scientific findings and potential clinical utility of heart rate variability measures in patients with systemic lupus erythematosus. Methods PubMed, Embase and Scopus databases were searched for the terms associated with systemic lupus erythematosus and heart rate variability, including controlled vocabulary, when appropriate. Articles published in English and available in full text were considered. Finally, 11 publications were selected, according to the systematic review protocol and were analyzed...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29694674/local-anaesthetics-and-regional-anaesthesia-versus-conventional-analgesia-for-preventing-persistent-postoperative-pain-in-adults-and-children
#18
REVIEW
Erica J Weinstein, Jacob L Levene, Marc S Cohen, Doerthe A Andreae, Jerry Y Chao, Matthew Johnson, Charles B Hall, Michael H Andreae
BACKGROUND: Regional anaesthesia may reduce the rate of persistent postoperative pain (PPP), a frequent and debilitating condition. This review was originally published in 2012 and updated in 2017. OBJECTIVES: To compare local anaesthetics and regional anaesthesia versus conventional analgesia for the prevention of PPP beyond three months in adults and children undergoing elective surgery. SEARCH METHODS: We searched CENTRAL, MEDLINE, and Embase to December 2016 without any language restriction...
April 25, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29693459/evaluating-the-effectiveness-of-systemic-corticosteroids-to-mitigate-relapse-in-children-assessed-and-treated-for-acute-asthma-a-network-meta-analysis
#19
Scott W Kirkland, Ben Vandermeer, Sandy Campbell, Cristina Villa-Roel, Amanda Newton, Francine M Ducharme, Brian H Rowe
OBJECTIVE: The objective of this systematic review was to explore the effectiveness of various systemic corticosteroid (SCS) regimens to mitigate relapse in children with asthma discharged from an acute care setting. DATA SOURCES: Medline, EMBASE, Global Health, International Pharmaceutical Abstracts, EMB ALL, CINAHL, SCOPUS, Proquest Dissertations and Theses Global, and LILACS were searched using controlled vocabulary and key words. Additional citations were searched via clinical trial registries, Google Scholar, bibliographies, a SCOPUS forward search of a sentinel paper, and hand searching conference abstracts...
April 25, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29691212/utilization-of-a-clinical-trial-management-system-for-the-whole-clinical-trial-process-as-an-integrated-database-system-development
#20
Yu Rang Park, Young Jo Yoon, HaYeong Koo, Soyoung Yoo, Chang-Min Choi, Sung-Ho Beck, Tae Won Kim
BACKGROUND: Clinical trials pose potential risks in both communications and management due to the various stakeholders involved when performing clinical trials. The academic medical center has a responsibility and obligation to conduct and manage clinical trials while maintaining a sufficiently high level of quality, therefore it is necessary to build an information technology system to support standardized clinical trial processes and comply with relevant regulations. OBJECTIVE: The objective of the study was to address the challenges identified while performing clinical trials at an academic medical center, Asan Medical Center (AMC) in Korea, by developing and utilizing a clinical trial management system (CTMS) that complies with standardized processes from multiple departments or units, controlled vocabularies, security, and privacy regulations...
April 24, 2018: Journal of Medical Internet Research
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