keyword
MENU ▼
Read by QxMD icon Read
search

Hydrogel

keyword
https://www.readbyqxmd.com/read/29035818/skin-penetrating-polymeric-nanoparticles-incorporated-in-silk-fibroin-hydrogel-for-topical-delivery-of-curcumin-to-improve-its-therapeutic-effect-on-psoriasis-mouse-model
#1
Kai-Li Mao, Zi-Liang Fan, Jian-Dong Yuan, Pian-Pian Chen, Jing-Jing Yang, Jie Xu, De-Li ZhuGe, Bing-Hui Jin, Qun-Yan Zhu, Bi-Xin Shen, Yasin Sohawon, Ying-Zheng Zhao, He-Lin Xu
A poor percutaneous penetration capability for most topical anti-inflammatory drugs is one of the main causes compromising their therapeutic effects on psoriatic skin. Even though curcumin has shown a remarkable efficacy in the treatment of psoriasis, its effective penetration through the stratum corneum is still a major challenge during transdermal delivery. The aim of our study was to design skin-permeating nanoparticles (NPs) to facilitate delivery of curcumin to the deeper layers of the skin. A novel amphiphilic polymer, RRR-α-tocopheryl succinate-grafted-ε-polylysine conjugate (VES-g-ε-PLL) was synthesized and self-assembled into polymeric nanoparticles...
October 10, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29035549/water-as-a-probe-of-colloidal-properties-of-cement
#2
Francesca Ridi, Monica Tonelli, Emiliano Fratini, Sow-Hsin Chen, Piero Baglioni
Cement is produced by mixing mineral phases based on calcium silicates and aluminates with water. The hydration reaction of the mixture leads to a synthetic material with outstanding properties that can be used as a binder for construction applications. Despite the importance of cement in society, for a long time, the chemical reactions involved in its hydration remained poorly understood due to the complexity of hydration processes, nanostructure and transport phenomena. This feature article reviews the recently obtained results using water as "a probe" to detail the essential features in the setting process...
October 16, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29035405/visible-light-mediated-cleavage-of-polymer-chains-under-physiological-conditions-via-quinone-photoreduction-and-trimethyl-lock
#3
Vinh X Truong, Fanyi Li, Francesca Ercole, John S Forsythe
We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.
October 16, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29035025/substrate-independent-ag-nanoparticles-loaded-hydrogel-coating-with-regenerable-bactericidal-and-thermo-responsive-anti-bacterial-properties
#4
Min He, Qian Wang, Jue Zhang, Weifeng Zhao, Changsheng Zhao
We report an Ag nanoparticles (AgNPs) based substrate independent bactericidal hydrogel coating with thermo-responsive anti-bacterial property. To attach the hydrogel coating onto model substrate, ene-functionalized dopamine was firstly coated on the substrate, and then the hydrogel thin layer was formed on the surface via the UV light initiated surface cross-linking copolymerization of N-isopropylacrylamide (NIPAAm) and sodium acrylate (AANa). Then, Ag ions were adsorbed into the hydrogel layers and reduced to AgNPs by sodium borohydride...
October 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29034553/synthesis-of-anisotropic-hydrogels-and-their-applications
#5
Koki Sano, Yasuhiro Ishida, Takuzo Aida
Owing to their water-rich structures similar to biological tissues, hydrogels have long been regarded as promising scaffolds for artificial tissues and organs. However, in terms of structural anisotropy, most synthetic hydrogels are substantially different from biological systems. Synthetic hydrogels are usually composed of randomly oriented three-dimensional polymer networks, whereas biological systems adopt anisotropic structures with hierarchically integrated building units. Such anisotropic structures often play an essential role in biological systems to exhibit their particular functions, as represented by muscular textures comprising unidirectionally oriented actin-myosin units...
October 16, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29034380/the-immobilization-of-antibiotic-loaded-polymeric-coatings-on-osteoarticular-ti-implants-for-the-prevention-of-bone-infections
#6
Dan Li, Pengfei Lv, Linfeng Fan, Yaoyi Huang, Fei Yang, Xifan Mei, Decheng Wu
Implant-associated infections in orthopaedic surgeries are very critical as they may hinder bone healing, cause implant failure and even progress to osteomyelitis. Drug-eluting implants for local delivery of antibiotics at surgical sites are thought to be promising in preventing infections. Herein, the antibiotic vancomycin was encapsulated in a poly(ethylene glycol) (PEG)-based hydrogel film that was covalently bound to Ti implants and subsequently covered by a PEG-poly(lactic-co-caprolactone) (PEG-PLC) membrane...
October 16, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/29034053/a-3d-printed-microbial-cell-culture-platform-with-in-situ-pegda-hydrogel-barriers-for-differential-substrate-delivery
#7
Andrea L Kadilak, Jessica C Rehaag, Cameron A Harrington, Leslie M Shor
Additive manufacturing, or 3D-printing techniques have recently begun to enable simpler, faster, and cheaper production of millifluidic devices at resolutions approaching 100-200 μm. At this resolution, cell culture devices can be constructed that more accurately replicate natural environments compared with conventional culturing techniques. A number of microfluidics researchers have begun incorporating additive manufacturing into their work, using 3D-printed devices in a wide array of chemical, fluidic, and even some biological applications...
September 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/29033538/comparison-of-a-hydrogel-corneal-inlay-and-monovision-laser-in-situ-keratomileusis-in-presbyopic-patients-focus-on-visual-performance-and-optical-quality
#8
Cornelis Verdoorn
PURPOSE: To compare the visual performance and optical quality after Raindrop Near Vision Inlay implantation or monovision LASIK for the correction of presbyopia. MATERIALS AND METHODS: In this retrospective case-series study, patients previously treated in the nondominant eye with monovision LASIK were compared with patients previously implanted with Raindrop Near Vision Inlay. The study enrolled 16 inlay and 15 monovision LASIK patients. Uncorrected near visual acuity, uncorrected distance visual acuity, binocular stereopsis, patient satisfaction, and patient task performance were assessed...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29032671/spectroelectrochemical-reverse-engineering-demonstrates-that-melanin-s-redox-and-radical-scavenging-activities-are-linked
#9
Eunkyoung Kim, Mijeong Kang, Tanya Tschirhart, Mackenzie Malo, Ekaterina Dadachova, Gaojuan Cao, Jun-Jie Yin, William E Bentley, Zheng Wang, Gregory F Payne
Melanins are ubiquitous in nature but their biological activities and functions have been difficult to discern. Conventional approaches to determine material function start by resolving structure and then characterize relevant properties. These approaches have been less successful for melanins because of their complex structure and insolubility, and because their relevant properties are not readily characterized by conventional methods. Here, we report a novel spectroelectrochemical reverse engineering approach that focuses on redox and radical scavenging activities...
October 15, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/29032216/gelatin-oxidized-carboxymethyl-cellulose-blend-based-tubular-electrospun-scaffold-for-vascular-tissue-engineering
#10
Jincy Joy, Jessica Pereira, Rachida Aid-Launais, Graciela Pavon-Djavid, Alok R Ray, Didier Letourneur, Anne Meddahi-Pellé, Bhuvanesh Gupta
The present work deals with the fabrication of electrospun tubular scaffold based on in-situ crosslinked blend of gelatin - oxidized carboxymethyl cellulose (OCMC) for vascular tissue engineering. The flow behavior and spinability of the hydrogel despite the in-situ crosslinked gelatin chains evaluated by Raman spectroscopic studies and rheological studies was utilized for electrospinning. The study highlights the tunable pore size and fiber diameter of the nanofibers with the manipulation of electrospinning parameters...
October 12, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29032194/in-situ-mucoadhesive-thermosensitive-liposomal-gel-as-a-novel-vehicle-for-nasal-extended-delivery-of-opiorphin
#11
Paola Mura, Natascia Mennini, Cristina Nativi, Barbara Richichi
Previous studies proved the effectiveness of an intravenous PEGylated liposomal formulation of opiorphin (1 mg/mL) in protecting the drug from enzymatic degradation, and improving intensity and duration of its painkilling effect. Therefore, considering the advantages of nasal administration, the aim of this work was the development of a liposomal mucoadhesive thermo-sensitive in situ gel for the extended nasal delivery of opiorphin. With this purpose, the potential of a series of combinations of different polymers (i...
October 12, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29031885/multiple-signal-amplification-via-ag-and-tio2-decorated-3d-nitrogen-doped-graphene-hydrogel-for-fabricating-sensitive-label-free-photoelectrochemical-thrombin-aptasensor
#12
Nan Hao, Rong Hua, Saibo Chen, Ying Zhang, Zhou Zhou, Jing Qian, Qian Liu, Kun Wang
In this study, Ag/TiO2/3D nitrogen doped graphene hydrogel (3DNGH) was prepared for the first time and the photocurrent intensity of this material was greatly enhanced, which was attributed to the multiple enhancements accomplished in one step. The porous structure of 3DNGH could provide an exceptionally large accessible surface area, which was beneficial for the anchoring of Ag and TiO2 nanoparticles. The introduction of nitrogen doped graphene and metal nanoparticles was capable to facilitate the charge separation efficiency and accelerate the transfer rate of the photogenerated electron-hole pairs...
October 8, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29030546/spontaneous-jumping-bouncing-and-trampolining-of-hydrogel-drops-on-a-heated-plate
#13
Jonathan T Pham, Maxime Paven, Sanghyuk Wooh, Tadashi Kajiya, Hans-Jürgen Butt, Doris Vollmer
The contact between liquid drops and hot solid surfaces is of practical importance for industrial processes, such as thermal spraying and spray cooling. The contact and bouncing of solid spheres is also an important event encountered in ball milling, powder processing, and everyday activities, such as ball sports. Using high speed video microscopy, we demonstrate that hydrogel drops, initially at rest on a surface, spontaneously jump upon rapid heating and continue to bounce with increasing amplitudes. Jumping is governed by the surface wettability, surface temperature, hydrogel elasticity, and adhesion...
October 13, 2017: Nature Communications
https://www.readbyqxmd.com/read/29030302/mesenchymal-stem-cell-therapy-for-retro-corneal-membrane-a-clinical-challenge-in-full-thickness-transplantation-of-biosynthetic-corneal-equivalents
#14
Vijayalakshmi Rajendran, Magdalena Netuková, May Griffith, John V Forrester, Lucia Kuffová
Artificial corneas (keratoprostheses) and biosynthetic collagen-based corneal equivalents are surgical implants designed to ease the global burden of corneal blindness. However, keratoprostheses in many cases fail due to development of fibrous retro-corneal membranes (RCM). Fibrous membranes which develop in the anterior chamber after prosthesis implantation do so on a matrix of fibrin. This study investigated fibrin deposition and RCM formation after full-thickness collagen-based hydrogel implants and compared them with syngeneic and allogeneic corneal grafts in mice...
October 10, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29030291/evaluation-of-a-spray-type-novel-dextrin-hydrogel-adhesion-barrier-under-laparoscopic-conditions-in-a-porcine-uterine-horn-adhesion-model
#15
Miho Kai, Kazuha Maeda, Masako Tasaki, Shinichirou Kira, Shintarou Nakamura, Naotaka Chino, Hitomi Hagiwara, Hitoshi Nishida, Tetsuro Kawanishi
STUDY OBJECTIVE: To establish a porcine uterine horn adhesion model that mimicked laparoscopic procedures and use it to investigate the effect of a spray-type, novel dextrin hydrogel adhesion barrier (AdSpray) on postsurgical adhesions. DESIGN: Single: Single-blind randomized controlled trial (Canadian Task Force Classification I). SETTING: Certified animal research facility. SUBJECTS: 16 female pigs. INTERVENTIONS: All animals underwent laparoscopically-assisted adhesion-inducing surgery...
October 10, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29030197/green-synthesis-of-degradable-conductive-thermosensitive-oligopyrrole-chitosan-hydrogel-intended-for-cartilage-tissue-engineering
#16
Mana Kashi, Fatemeh Baghbani, Fathollah Moztarzadeh, Hamid Mobasheri, Elaheh Kowsari
Electroactive scaffolds containing conductive polymers can promote tissue repair and regeneration. However, these polymers are non-degradable and cannot be removed from body. To overcome this limitation of conductive polymers, we developed a novel injectable electroactive hydrogel containing pyrrole oligomers which possessed the unique properties of being both electrically conductive and biodegradable. First, pyrrole oligomers were synthesized via chemical polymerization and were found to be amorphous with a non-globular morphology...
October 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29030190/design-of-a-ph-sensitive-magnetic-composite-hydrogel-based-on-salecan-graft-copolymer-and-fe3o4-sio2-nanoparticles-as-drug-carrier
#17
Xinyu Hu, Yongmei Wang, Liangliang Zhang, Man Xu, Jianfa Zhang, Wei Dong
Salecan, a novel water-soluble extracellular β-glucan, is very suitable for the hydrogel preparation. Here, pH-sensitive magnetic composite hydrogel was fabricated by the graft copolymerization of crotonic acid (CA) and N-(hydroxymethyl) acrylamide (HMAA) onto salecan in the presence of Fe3O4@SiO2 nanoparticles for doxorubicin (DOX) delivery. The embedment of Fe3O4@SiO2 nanoparticles into salecan-g-poly(CA-co-HMAA) hydrogel network endowed the material with magnetic property. In addition, DOX not only achieved effectively bound to the composite hydrogel, but also released in a controlled and pH-dependent manner...
October 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29029744/hydrogels-of-polyaniline-with-graphene-oxide-for-highly-sensitive-electrochemical-determination-of-lead-ions
#18
S Muralikrishna, D H Nagaraju, R Geetha Balakrishna, Werasak Surareungchai, T Ramakrishnappa, Avinash B Shivanandareddy
Conducting polymers with graphene/graphene oxide hydrogels represent a unique class of electrode materials for sensors and energy storage applications. In this article, we report a facile in situ method for the polymerisation of aniline resulting in the decoration of 1D conducting polyaniline (PANI) nanofibers onto the surface of 2D graphene oxide (GO) nanosheets followed by hydrogel formation at elevated temperature. The synthesized nanomaterial exhibits significant properties for the highly sensitive electrochemical determination as well as removal of environmentally harmful lead (Pb(2+)) ions...
October 16, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29029265/preclinical-testing-of-a-broad-spectrum-antimicrobial-endotracheal-tube-coated-with-an-innate-immune-synthetic-mimic
#19
Marjan M Hashemi, John Rovig, Jordan Bateman, Brett S Holden, Tomasz Modelzelewski, Iliana Gueorguieva, Martin von Dyck, Ronald Bracken, Carl Genberg, Shenglou Deng, Paul B Savage
Background: Endotracheal tubes provide an abiotic surface on which bacteria and fungi form biofilms, and the release of endotoxins and planktonic organisms can cause damaging inflammation and infections. Objectives: Ceragenins are small molecule mimics of antimicrobial peptides with broad-spectrum antibacterial and antifungal activity, and a ceragenin may be used to provide antimicrobial protection to the abiotic surface of an endotracheal tube. Methods: A hydrogel film, containing CSA-131, was generated on endotracheal tubes...
October 4, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29029228/development-of-a-whole-task-simulator-for-carotid-endarterectomy
#20
Gabrielle Santangelo, Doran Mix, Ahmed Ghazi, Michael Stoner, G Edward Vates, Jonathan J Stone
BACKGROUND: Surgical education relies on operative exposure with live patients. Carotid endarterectomy (CEA) demands an experienced surgeon with a very low complication rate. The high-risk nature of this procedure and the decline in number of CEAs performed annually has created a gap in residency training. OBJECTIVE: To develop a high-fidelity whole-task simulation for CEA that demonstrates content, construct, and face validity. METHODS: Anatomically accurate models of the human neck were created using multilayered poly-vinyl alcohol hydrogels...
September 27, 2017: Operative Neurosurgery (Hagerstown, Md.)
keyword
keyword
6141
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"