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Autoimmune nutrition

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https://www.readbyqxmd.com/read/28185175/blood-levels-of-lead-and-mercury-and-celiac-disease-seropositivity-the-us-national-health-and-nutrition-examination-survey
#1
Elena Kamycheva, Tadahiro Goto, Carlos A Camargo
Celiac disease (CD) is an autoimmune disease with increasing prevalence in the USA. CD leads to decreased absorption of many nutrients including certain divalent metals. On the other hand, recent cross-sectional studies suggest the associations between trace heavy metal exposure and autoimmunity. We aimed to determine if there is an association between CD autoimmunity and blood levels of heavy metals in the general US population. We used nationally representative data from National Health and Nutrition Examination Survey, 2009-2012...
February 9, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28144744/food-matters-how-the-microbiome-and-gut-brain-interaction-might-impact-the-development-and-course-of-anorexia-nervosa
#2
REVIEW
Beate Herpertz-Dahlmann, Jochen Seitz, John Baines
Anorexia nervosa (AN) is one of the most common chronic illnesses in female adolescents and exhibits the highest mortality risk of all psychiatric disorders. Evidence for the effectiveness of psychotherapeutic or psychopharmacological interventions is weak. Mounting data indicate that the gut microbiome interacts with the central nervous system and the immune system by neuroendocrine, neurotransmitter, neurotrophic and neuroinflammatory afferent and efferent pathways. There is growing evidence that the gut microbiota influences weight regulation and psychopathology, such as anxiety and depression...
January 31, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28144390/predictors-for-advanced-fibrosis-in-morbidly-obese-non-alcoholic-fatty-liver-patients
#3
Shira Zelber-Sagi, Dafna Shoham, Isabel Zvibel, Subhi Abu-Abeid, Oren Shibolet, Sigal Fishman
AIM: To investigate predictors for fibrosis specifically in a high risk population of morbidly obese patients, including detailed evaluation of lifestyle. METHODS: We conducted a cross-sectional study among morbidly obese patients attending the bariatric clinic at the Tel-Aviv Medical Center between the years 2013-2014 with body mass index (BMI) above 40 or above 35 with co-morbidity. Patients with serum hepatitis B surface antigen or anti-hepatitis C virus antibodies, genetic liver diseases, autoimmune disease or high alcohol intake (≥ 30 g/d in men or ≥ 20 g/d in women) were excluded from the study...
January 18, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28137612/nutrition-and-fasting-mimicking-diets-in-the-prevention-and-treatment-of-autoimmune-diseases-and-immunosenescence
#4
In Young Choi, Changhan Lee, Valter D Longo
Complex and coordinated signals are necessary to initiate and sustain the activation, proliferation, and differentiation of lymphocytes. These signals, which are known to determine T-cell fate and function, also depend on the metabolic state of the organism. Recent studies indicate that both the type and levels of nutrients can influence the generation, survival and function of lymphocytes and therefore can affect several autoimmune diseases. Here, we review the dysregulation of lymphocytes during autoimmunity and aging, the mechanisms associated with loss of immune function, and how fasting mimicking diets and other dietary interventions affect autoimmunity and immunosenescence...
January 27, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28104447/celiac-disease-autoimmunity-is-associated-with-leukocyte-telomere-shortening-in-older-adults-the-u-s-national-health-and-nutrition-examination-survey
#5
Elena Kamycheva, Tadahiro Goto, Carlos A Camargo
PURPOSE: Telomeres are nucleotide sequences, and their function is to maintain cell surveillance. Exaggeration of the attrition rate of leukocyte telomere length (LTL) may result in genomic instability and tumorigenesis. Celiac disease (CD), an autoimmune inflammation of small intestine, has increasing prevalence in the elderly and may lead to lymphomas and gastrointestinal malignancies. We used nationally-representative datasets from the U.S. National Health and Nutrition Examination Survey (NHANES) to investigate if CD autoimmunity in older adults (age≥50years) is associated with shorter LTL...
January 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28101619/-all-rounder-vitamin%C3%A2-d
#6
S Unholzer, A Rothmund, E Haen
BACKGROUND: Many indications are discussed for vitamin D substitution, such as osteoporosis, autoimmune diseases, cancer and psychiatric diseases. Also discussed is the fact that the majority of the German population suffer from a vitamin D deficiency. OBJECTIVE: Review of the study results for these individual diseases and a critical analysis of the currently established therapeutic reference range, which defines a vitamin D deficiency. MATERIAL AND METHODS: A literature search was carried out in the statements of the German Society for Nutrition, in scientific publications and journals...
January 18, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28092152/issues-in-nutrition-dietary-considerations-in-select-chronic-conditions
#7
Margaret E Thompson, Mary Barth Noel
Chronic diseases that affect the gastrointestinal tract also tend to affect nutrition. The incidence of chronic liver disease is increasing. As the prevalence of obesity rises, so do the incidences of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Patients with chronic liver disease usually have some degree of malnutrition. In the absence of encephalopathy, patients with chronic liver disease should consume more protein than that in the average diet. There is some controversy about whether diet plays a role in the development of inflammatory bowel disease...
January 2017: FP Essentials
https://www.readbyqxmd.com/read/28067892/impact-of-type-1-diabetes-mellitus-and-celiac-disease-on-nutrition-and-quality-of-life
#8
J G Nunes-Silva, V S Nunes, R P Schwartz, S Mlss Trecco, D Evazian, M L Correa-Giannella, M Nery, M S Queiroz
OBJECTIVE: Type 1 diabetes mellitus (T1DM) and celiac disease (CD) are autoimmune diseases and have similar genetic patterns. T1DM treatment is based on diet, physical activity and insulin therapy, whereas CD depends on dietary changes with restriction of wheat, rye and barley. The aim of the study was to evaluate the quality of life (QoL) of individuals with the association of T1DM and CD, to characterize their nutritional status and to compare it with those with only one disease and healthier controls...
January 9, 2017: Nutrition & Diabetes
https://www.readbyqxmd.com/read/28053336/leptin-in-the-interplay-of-inflammation-metabolism-and-immune-system-disorders
#9
REVIEW
Vanessa Abella, Morena Scotece, Javier Conde, Jesús Pino, Miguel Angel Gonzalez-Gay, Juan J Gómez-Reino, Antonio Mera, Francisca Lago, Rodolfo Gómez, Oreste Gualillo
Leptin is one of the most relevant factors secreted by adipose tissue and the forerunner of a class of molecules collectively called adipokines. Initially discovered in 1994, its crucial role as a central regulator in energy homeostasis has been largely described during the past 20 years. Once secreted into the circulation, leptin reaches the central and peripheral nervous systems and acts by binding and activating the long form of leptin receptor (LEPR), regulating appetite and food intake, bone mass, basal metabolism, reproductive function and insulin secretion, among other processes...
January 5, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28028951/increased-expression-of-tlr4-and-tlr7-but-not-prolactin-mrna-by-peripheral-blood-monocytes-in-active-celiac-disease
#10
Iva Brynychova, Iva Hoffmanova, Milos Dvorak, Pavlina Dankova
BACKGROUND: Celiac disease (CD) is an organ-specific autoimmune disease, and both adaptive and innate immunity are involved in its development. OBJECTIVES: The aim of the study was to determine whether the markers of intestinal mucosal inflammation in CD can be detected in peripheral blood monocytes (PBMs), and whether the immune properties of PBMs change as the clinical signs and symptoms of CD improve after the introduction of a gluten-free diet (GFD). The focus was on changes in mRNA expression of selected toll-like receptors (TLR2, TLR4, TLR7), stress cytokine prolactin (PRL), and proand anti-inflammatory cytokines (TNF-α, IL-6, IL-12, IL-10) in PBMs...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/27994896/proximal-limb-weakness-in-a-patient-with-celiac-disease-copper-deficiency-gluten-sensitivity-or-both-as-the-underlying-cause
#11
J David Avila, David Lacomis
Celiac disease has been associated with several neurologic disorders which may result from micronutrient deficiencies, coexisting autoimmune conditions, or gluten sensitivity. Copper deficiency can produce multiple neurologic manifestations. Myeloneuropathy is the most common neurologic syndrome and it is often irreversible, despite copper replacement. We report the case of a 55-year-old man who presented with progressive proximal limb weakness and weight loss in the setting of untreated celiac disease without gastrointestinal symptoms...
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/27959843/-prevalence-of-thyroid-dysfunction-in-patients-with-type-2-diabetes-mellitus
#12
Mirta Centeno Maxzud, Luciana Gómez Rasjido, Mercedes Fregenal, Florencia Arias Calafiore, Mercedes Córdoba Lanus, Marcela D'Urso, Héctor Luciardi
Diabetes mellitus (DM) and thyroid dysfunction (TD) are two common endocrine disorders. The unrecognized subclinical TD may adversely affect metabolic control and increase cardiovascular risk. Our aim was to investigate the prevalence of TD in patients with type 2 diabetes mellitus in an observational cross-sectional study. Clinical and laboratory evaluation was performed to 205 consecutive outpatients at Endocrinology Diabetes and Nutrition Center in Concepcion City, Tucuman, Argentina. Thyroid dysfunction was classified as clinical hypothyroidism with TSH > 4...
2016: Medicina
https://www.readbyqxmd.com/read/27871350/early-description-of-diet-induced-blistering-skin-diseases-in-medieval-persia-avicenna-s-point-of-view
#13
Fatemeh Atarzadeh, Babak Daneshfard, Ladan Dastgheib, Amir-Mohammad Jaladat, Gholamreza Amin
Pemphigus is an autoimmune blistering skin disease that is strongly associated with different environmental factors. Among these, nutritional factors are considered to trigger pemphigus; however, their role may be underestimated. Investigated more recently in conventional medicine, this causative bond between dietary factors and blistering skin diseases was mentioned by Persian scholars such as Avicenna a thousand years ago. Avicenna, a well-known Persian physician and philosopher, who could be considered a pioneer in dermatology, discussed skin diseases in a chapter in The Canon of Medicine...
2016: Skinmed
https://www.readbyqxmd.com/read/27855237/insulin-autoimmune-syndrome-a-rare-cause-of-postprandial-hypoglycemia
#14
Pooja Sahni, Nitin Trivedi, Abdulkadir Omer
: A 65-year-old obese Caucasian woman presented with symptomatic postprandial hypoglycemic episodes, resolution of symptoms with carbohydrate intake and significantly elevated anti-insulin antibody levels. She did not have any evidence for the use of oral antidiabetic medications, insulin, herbal substances, performing strenuous exercise or history of bariatric surgery. Fingerstick blood glucose readings revealed blood sugar of 35 mg/dL and 48 mg/dL, when she had these symptoms. Her medical history was significant for morbid obesity, hypothyroidism and gastro esophageal reflux disease...
2016: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/27815799/cla-has-a-useful-effect-on-bone-markers-in-patients-with-rheumatoid-arthritis
#15
N Aryaeian, F Shahram, M Djalali
: Rheumatoid arthritis is a systemic, chronic disease which may increase the risk of osteoporosis. This study was carried out in order to examine the effect of conjugated linoleic acid (CLA) on bone markers in rheumatoid arthritis disease which is the most common autoimmune disease. The present study is a randomized double-blind clinical trial. Subjects included 52 patients with active rheumatoid arthritis who were divided into two groups. Group I received standard treatment plus 2 daily 1...
November 4, 2016: Lipids
https://www.readbyqxmd.com/read/27799014/effect-of-marijuana-use-on-thyroid-function-and-autoimmunity
#16
Sonali Malhotra, Rubina A Heptulla, Peter Homel, Roja Motaghedi
BACKGROUND: Marijuana is legalized for medical use in 24 states and for recreational use in 5. However, effects of marijuana use on thyroid function and autoimmunity are unknown. METHODS: We performed a cross-sectional analysis of data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2007 and 2012 to assess the effects of marijuana on thyroid function and autoimmunity in users. We included 5280 adults ages 18 to 69 years, who responded to questions related to marijuana use and had laboratory results related to thyroid parameters...
February 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27783083/extra-virgin-olive-oil-a-key-functional-food-for-prevention-of-immune-inflammatory-diseases
#17
REVIEW
Marina Aparicio-Soto, Marina Sánchez-Hidalgo, Ma Ángeles Rosillo, Ma Luisa Castejón, Catalina Alarcón-de-la-Lastra
Nowadays, it is clear that an unhealthy diet is one of the prime factors that contributes to the rise of inflammatory diseases and autoimmunity in the populations of both developed and developing countries. The Mediterranean diet has been associated with a reduced incidence of certain pathologies related to chronic inflammation and the immune system. Olive oil, the principal source of dietary lipids of the Mediterranean diet, possesses a high nutritional quality and a particular composition, which is especially relevant in the case of Extra Virgin Olive Oil (EVOO)...
November 9, 2016: Food & Function
https://www.readbyqxmd.com/read/27714440/celiac-disease-is-associated-with-reduced-bone-mineral-density-and-increased-frax-scores-in-the-us-national-health-and-nutrition-examination-survey
#18
E Kamycheva, T Goto, C A Camargo
: We investigated the association between celiac disease (CD) and bone mass density (BMD) and risk of osteoporotic fractures in the general US population. In children and men ≥18 years, CD was associated with reduced BMD, and in men ≥40 years, CD was associated with increased risk of osteoporotic fractures. INTRODUCTION: Celiac disease (CD) is an autoimmune condition, characterized by inflammation of the small intestine. CD has an increasing prevalence, and if unrecognized or untreated, CD can lead to complications from malabsorption and micronutrient deficiencies...
March 2017: Osteoporosis International
https://www.readbyqxmd.com/read/27684858/low-serum-albumin-concentrations-are-associated-with-disease-severity-in-patients-with-myasthenia-gravis
#19
Yi-Yun Weng, De-Hao Yang, Mei-Zi Qian, Mao-Mao Wei, Fang Yin, Jia Li, Xiang Li, Ying Chen, Zhang-Na Ding, Yi-Bo He, Xu Zhang
Serum albumin (S-Alb) is a widely used biomarker of nutritional status and disease severity in patients with autoimmune diseases. We investigated the correlation between S-Alb and the severity of myasthenia gravis (MG).A total number of 166 subjects were recruited in the study. Subjects were divided into 3 groups (T1 to T3) by S-Alb levels: T1: 21.1 to 38.4 g/L, T2: 38.5 to 41.5 g/L, T3: 41.6 to 48.9 g/L. Regression analysis was performed to determine the correlation of initial albumin concentrations and the severity of disease of MG...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27667580/insights-into-the-pathogenesis-of-mycoplasma-pneumoniae-review
#20
Jun He, Mihua Liu, Zhufeng Ye, Tianping Tan, Xinghui Liu, Xiaoxing You, Yanhua Zeng, Yimou Wu
Mycoplasma are the smallest prokaryotic microbes present in nature. These wall‑less, malleable organisms can pass through cell filters, and grow and propagate under cell‑free conditions in vitro. Of the pathogenic Mycoplasma Mycoplasma pneumoniae has been examined the most. In addition to primary atypical pneumonia and community‑acquired pneumonia with predominantly respiratory symptoms, M. pneumoniae can also induce autoimmune hemolytic anemia and other diseases in the blood, cardiovascular system, gastrointestinal tract and skin, and can induce pericarditis, myocarditis, nephritis and meningitis...
November 2016: Molecular Medicine Reports
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