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https://www.readbyqxmd.com/read/29238648/trends-in-spinal-surgery-for-pott-s-disease-2000-2016-an-overview-and-bibliometric-study
#1
Christian Fisahn, Fernando Alonso, Ghazwan A Hasan, R Shane Tubbs, Joseph R Dettori, Thomas A Schildhauer, Tarush Rustagi
Study Design: Systematic review. Objectives: (1) What are the surgical indications? Have they changed over time since the year 2000? (2) What is the current surgical approaches of choice? Have they changed over time since the year 2000? Do they vary by geographical region? (3) What are the most common outcome measures following surgery? Methods: Electronic databases and reference lists of key articles were searched from database inception from January 1, 2000 to December 31, 2016 to identify studies specifically evaluating surgical indications, current surgical approaches, and outcome measures for spinal tuberculosis...
December 2017: Global Spine Journal
https://www.readbyqxmd.com/read/29236861/plant-species-diversity-in-a-neotropical-wetland-patterns-of-similarity-effects-of-distance-and-altitude
#2
Francielli Bao, Thales D Leandro, Maíra DA Rocha, Vanessa S Dos Santos, Thiago H Stefanello, Rafael Arruda, Arnildo Pott, Geraldo A Damasceno-Júnior
The Brazilian Pantanal is an extensive wetland with heterogeneous habitats, primarily due to the river-floodplain system and plants with differential adaptations and reproductive strategies. Factors such as altitude, distance among plant formations, and flood pulse must be considered to better understand its diversity. Aiming to assess the influence of biogeographic patterns in this system, we analyzed the floristic composition of six areas along the Paraguay River, including residual relieves, verifying the pattern of similarity, and effects of distance and altitude...
December 7, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29234660/monosegmental-combined-anterior-posterior-instrumentation-for-the-treatment-of-a-severe-lumbar-tuberculous-spondylodiscitis-case-report-and-literature-review
#3
Petracchi Matias, Camino Willhuber Gaston, Tripodi Maria, Bassani Julio, Gruenberg Marcelo, Sola Carlos
Spinal tuberculosis (Pott disease) can produce severe deformities when it is not properly treated. Long instrumentations through single or combined double approaches are usually required to prevent and correct the deformity. The authors present a case of severe deformity secondary to tuberculous spondylodiscitis in the lumbar spine treated with a monosegmental instrumentation through a double approach in a patient with idiopathic scoliosis. Deformity correction and infection resolution through debridement and arthrodesis is observed after one year of follow-up...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29225229/nhs-based-tandem-mass-tagging-of-proteins-at-the-level-of-whole-cells-a-critical-evaluation-in-comparison-to-conventional-tmt-labeling-approaches-for-quantitative-proteome-analysis
#4
Dominik A Megger, Leona L Pott, Kristin Rosowski, Birgit Zülch, Stephanie Tautges, Thilo Bracht, Barbara Sitek
Tandem mass tags (TMT) are usually introduced at the levels of isolated proteins or peptides. Here, for the first time, we report the labeling of whole cells and a critical evaluation of its performance in comparison to conventional labeling approaches. The obtained results indicated that TMT protein labeling using intact cells is generally possible, if it is coupled to a subsequent enrichment using anti-TMT antibody. The quantitative results were similar to those obtained after labeling of isolated proteins and both were found to be slightly complementary to peptide labeling...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/29225034/cytosolic-iron-sulfur-assembly-is-evolutionarily-tuned-by-a-cancer-amplified-ubiquitin-ligase
#5
Jenny L Weon, Seung Wook Yang, Patrick Ryan Potts
The cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway functions to incorporate inorganic Fe-S cofactors into a variety of proteins, including several DNA repair enzymes. However, the mechanisms regulating the CIA pathway are unknown. We describe here that the MAGE-F1-NSE1 E3 ubiquitin ligase regulates the CIA pathway through ubiquitination and degradation of the CIA-targeting protein MMS19. Overexpression or knockout of MAGE-F1 altered Fe-S incorporation into MMS19-dependent DNA repair enzymes, DNA repair capacity, sensitivity to DNA-damaging agents, and iron homeostasis...
November 30, 2017: Molecular Cell
https://www.readbyqxmd.com/read/29218392/unusual-circumstances-to-diagnose-cervical-pott-s-disease
#6
Mohamed Ali Kedous, Ahmed Msakni, Wael Chebbi, Mourad Zaraa, Mohsen Trabelsi
Tuberculous spondylodiscitis usually affects the dorso-lumbar spine, and its cervical location is a rare condition that can mimic other diseases and consequently cause treatment delays. We report a case of tuberculous spondylodiscitis of the lower cervical spine discovered under unusual circumstances in a patient with severe polytrauma involving a cranio-cerebral trauma, a non-displaced fracture of the two laminæ and the spinous process of the C6 vertebrae as well as fibular and tibial shaft fractures. The patient underwent static tibial nailing, and a collar with occipital and chin supports was applied...
December 7, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29204894/the-development-of-the-genital-psoriasis-sexual-frequency-questionnaire-genps-sfq-to-assess-the-impact-of-genital-psoriasis-on-sexual-health
#7
Alice B Gottlieb, Brian Kirby, Caitriona Ryan, April N Naegeli, Russel Burge, Alison Potts Bleakman, Milena D Anatchkova, Jennifer Cather
INTRODUCTION: Patient-reported outcome measures (PROs) exist for psoriasis but not genital psoriasis (GenPs). METHODS: This cross-sectional, qualitative study in patients with moderate-to-severe GenPs was conducted to support development of a PRO for measuring the impact of GenPs on sexual activity and to establish content validity. The impacts of GenPs were identified in a literature review. Findings from the literature review were discussed with clinicians, and then patients with GenPs were interviewed...
December 4, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/29204893/the-development-of-a-patient-reported-outcome-measure-for-assessment-of-genital-psoriasis-symptoms-the-genital-psoriasis-symptoms-scale-gpss
#8
Alice B Gottlieb, Brian Kirby, Caitriona Ryan, April N Naegeli, Russel Burge, Alison Potts Bleakman, Milena D Anatchkova, Gil Yosipovitch
INTRODUCTION: Patient-reported outcome measures (PROs) specific for genital psoriasis (GenPs) have not been described. METHODS: In this cross-sectional, qualitative study in patients with moderate-to-severe GenPs, we sought to develop a PRO useful for GenPs symptom assessment. A literature review was performed to identify relevant psoriasis or GenPs symptoms and existing PROs that may be useful in the evaluation of symptom severity in GenPs patients. The literature review findings were discussed with clinicians, and then patients with GenPs...
December 4, 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/29200933/dimensions-of-biodiversity-loss-spatial-mismatch-in-land-use-impacts-on-species-functional-and-phylogenetic-diversity-of-european-bees
#9
Adriana De Palma, Michael Kuhlmann, Rob Bugter, Simon Ferrier, Andrew J Hoskins, Simon G Potts, Stuart P M Roberts, Oliver Schweiger, Andy Purvis
Aim: Agricultural intensification and urbanization are important drivers of biodiversity change in Europe. Different aspects of bee community diversity vary in their sensitivity to these pressures, as well as independently influencing ecosystem service provision (pollination). To obtain a more comprehensive understanding of human impacts on bee diversity across Europe, we assess multiple, complementary indices of diversity. Location: One Thousand four hundred and forty six sites across Europe...
December 2017: Diversity & Distributions
https://www.readbyqxmd.com/read/29198597/the-position-of-the-aorta-relative-to-the-spine-in-patients-with-pott-s-thoracolumbar-angular-kyphosis
#10
Yan Liang, Yongfei Zhao, Haiying Liu, Zheng Wang
STUDY DESIGN: Analyze the position of the aorta in patients with Pott's thoracolumbar angular kyphosis by computed tomography. OBJECTIVE: To investigate the anatomic position of the aorta relative to spine in patients with Pott's thoracolumbar angular kyphosis. SUMMARY OF BACKGROUND DATA: The complication of aorta injury is rare in the procedure of spinal osteotomy for the correction of Pott's thoracolumbar angular kyphotic deformity. However, there would be a disastrous consequence once it happened...
November 30, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29181891/fluid-structure-interaction-of-a-pulsatile-flow-with-an-aortic-valve-model-a-combined-experimental-and-numerical-study
#11
J Sigüenza, D Pott, S Mendez, S J Sonntag, T A S Kaufmann, U Steinseifer, F Nicoud
The complex fluid-structure interaction problem associated with the flow of blood through a heart valve with flexible leaflets is investigated both experimentally and numerically. In the experimental test rig, a pulse duplicator generates a pulsatile flow through a biomimetic rigid aortic root where a model of aortic valve with polymer flexible leaflets is implanted. High-speed recordings of the leaflets motion and Particle Image Velocimetry measurements were performed together to investigate the valve kinematics and the dynamics of the flow...
November 27, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/29171360/canadian-stroke-best-practice-consensus-statement-secondary-stroke-prevention-during-pregnancy
#12
Richard H Swartz, Noor Niyar N Ladhani, Norine Foley, Kara Nerenberg, Simerpreet Bal, Jon Barrett, Cheryl Bushnell, Wee-Shian Chan, Radha Chari, Dariush Dowlatshahi, Meryem El Amrani, Shital Gandhi, Gord Gubitz, Michael D Hill, Andra James, Thomas Jeerakathil, Albert Jin, Adam Kirton, Sylvain Lanthier, Andrea Lausman, Lisa Rae Leffert, Jennifer Mandzia, Bijoy Menon, Aleksandra Pikula, Alexandre Poppe, Jayson Potts, Joel Ray, Gustavo Saposnik, Mukul Sharma, Eric E Smith, Sanjit Bhogal, Elisabeth Smitko, M Patrice Lindsay
The Canadian Stroke Best Practice Consensus Statement: Secondary Stroke Prevention during Pregnancy, is the first of a two-part series devoted to stroke in pregnancy. This document focuses on unique aspects of secondary stroke prevention in a woman with a prior history of stroke or transient ischemic attack who is, or is planning to become, pregnant. Although stroke is relatively rare in this cohort, several aspects of pregnancy can increase stroke risk during or immediately after pregnancy. The rationale for the development of this consensus statement is based on the premise that stroke in this group requires a specifically-tailored management approach...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29169784/fast-track-registration-a-way-to-increase-efficiency-in-the-ir-division
#13
David P Duncan, Bryan E Wessel, Michael A Schacht, Lu Anne V Dinglasan, George W Mader, Melissa H Potts, Mahmoud Samman, Martin S Vyleta, Douglas M Coldwell
PURPOSE: To evaluate changes in patient registration process at an academic 2-suite IR Division to determine if moving registration from the waiting room to the vascular holding area decreased amount of time patients spent in the Radiology Department and improved start times. MATERIALS AND METHODS: A data collection sheet was created by evaluating patient-related processes; event timestamps were recorded on the sheet. The control group consisted of 33 patients who registered using the traditional process...
November 21, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29167138/recent-advances-in-management-of-autosomal-dominant-polycystic-kidney-disease
#14
REVIEW
Jacob W Potts, Shaker A Mousa
PURPOSE: Promising developments in the search for effective pharmacotherapies for autosomal-dominant polycystic kidney disease (ADPKD) are reviewed. SUMMARY: The formation and development of cysts characteristic of ADPKD result in inexorable renal and extrarenal manifestations that give rise to more rapid disease progression and more widespread complications than are seen with other forms of chronic kidney disease. To date, no agent has gained Food and Drug Administration marketing approval for use in patients with ADPKD, complicating efforts to meet the medical needs of this population...
December 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29166545/occurrence-of-primarily-noninducible-atrioventricular-nodal-reentry-tachycardia-after-radiofrequency-delivery-in-the-slow-pathway-region-during-empirical-slow-pathway-modulation
#15
Felix Konrad Wegner, Nils Bögeholz, Patrick Leitz, Gerrit Frommeyer, Dirk Georg Dechering, Simon Kochhäuser, Philipp Sebastian Lange, Julia Köbe, Kristina Wasmer, Gerold Mönnig, Lars Eckardt, Christian Pott
BACKGROUND: The first-line therapy for atrioventricular nodal reentry tachycardia (AVNRT) is catheter-based slow pathway modulation. If AVNRT is not inducible during an electrophysiological study, an empirical slow pathway modulation (ESPM) may be considered in patients with dual atrioventricular nodal physiology and/or a typical electrocardiogram (ECG). METHODS: We screened 149 symptomatic patients who underwent ESPM in our department between 1993 and 2013. All patients fulfilled the following criteria: (1) either dual atrioventricular nodal (AVN) physiology with up to 2 AVN echo beats or characteristic ECG documentation or both, (2) noninducibility of AVNRT by programmed stimulation, and (3) completion of a telephone questionnaire for long-term follow-up...
November 22, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29162264/retraction-notice-to-nad-p-h-quinone-oxioreductase-1-protects-lungs-from-oxidant-induced-emphysema-in-mice-frb-52-3-2012-705-715
#16
Erin N Potts-Kant, Zhuowei Li, Robert M Tighe, James Y Lindsey, Benjamin W Frush, W Michael Foster, John W Hollingsworth
No abstract text is available yet for this article.
December 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29157751/preliminary-evidence-that-digit-length-ratio-2d-4d-predicts-neural-response-to-delivery-of-motivational-stimuli
#17
Troy A Webber, Heather E Soder, Geoffrey F Potts, Marina A Bornovalova
Reduced relative length of the 2nd to 4th digits (2D:4D) is thought to partially reflect fetal testosterone (FT) exposure, a process suspected to promote relatively permanent effects on the brain and behavior via structural and functional neuroadaptations. We examined the effect of 2D:4D on neural response - assessed by P2a and feedback-related negativity (FRN) event-related potentials (ERPs) - to motivational stimuli (reward or punishment) using two counterbalanced conditions of a passive S1/S2 outcome prediction design...
November 17, 2017: Biological Psychology
https://www.readbyqxmd.com/read/29157471/case-reports-on-integrated-management-of-tubercular-disease
#18
Kusum S Chand, Priya Kapoor
BACKGROUND: Host immunity plays an important role in prevention of disease as is evident by the increased incidence of Tuberculosis (TB) in immuno-compromised population of HIV infected, diabetes inflicted, immune-suppressant therapy and elderly people. Rising incidence of antibiotic resistance has led to resurgence of TB of epidemic proportions. Integrated treatment with add on homeopathy in addition to anti-tuberculosis treatment (ATT) appears to improve outcome in TB. The intervention has been integrated treatment with homeopathy regime, which is using a patient specific, disease specific and supportive medicine simultaneously, all individualized for the patient and the disease...
November 2017: Homeopathy: the Journal of the Faculty of Homeopathy
https://www.readbyqxmd.com/read/29150605/global-role-of-the-bacterial-post-transcriptional-regulator-csra-revealed-by-integrated-transcriptomics
#19
Anastasia H Potts, Christopher A Vakulskas, Archana Pannuri, Helen Yakhnin, Paul Babitzke, Tony Romeo
CsrA is a post-transcriptional regulatory protein that is widely distributed among bacteria. This protein influences bacterial lifestyle decisions by binding to the 5' untranslated and/or early coding regions of mRNA targets, causing changes in translation initiation, RNA stability, and/or transcription elongation. Here, we assess the contribution of CsrA to gene expression in Escherichia coli on a global scale. UV crosslinking immunoprecipitation and sequencing (CLIP-seq) identify RNAs that interact directly with CsrA in vivo, while ribosome profiling and RNA-seq uncover the impact of CsrA on translation, RNA abundance, and RNA stability...
November 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/29149920/gastrointestinal-and-hepatic-disease-in-the-inflammatory-myopathies
#20
REVIEW
Chiranjeevi Gadiparthi, Amneet Hans, Kyle Potts, Mohammad K Ismail
Although muscle weakness is the pathognomonic feature of idiopathic inflammatory myopathies, systemic organ involvement is not uncommon. The gastrointestinal and hepatic manifestations are well known. Oropharyngeal dysphagia is the most common gastrointestinal symptom and can be severe. Gastric and small intestinal motility disorders, including chronic intestinal pseudo-obstruction, celiac disease, and inflammatory bowel disease have been described. Comprehensive cancer screening is warranted soon after the diagnosis of inflammatory myopathies due to high risk of occult malignancies...
February 2018: Rheumatic Diseases Clinics of North America
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