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David J Birnbaum, François Bertucci, Pascal Finetti, Daniel Birnbaum, Emilie Mamessier
Clinico-pathological factors fail to consistently predict the outcome after pancreatic resection for pancreatic ductal adenocarcinoma (PDAC). PDACs show a high level of inter- and intra- tumor genetic heterogeneity. A molecular classification should help sort patients into less heterogeneous and more appropriate groups regarding the metastatic risk and the therapeutic response, with the consequences of better predicting evolution and better orienting the treatment. PDAC can be classified based on mutational subtypes and 18gene alterations...
April 2018: Biochimica et Biophysica Acta
C de Barros Mott, D R Guarita, J Noya Costa Lima, V P Conte, M Cerqueira, C Machado, P Bove, A Raia, A Bettarello
No abstract text is available yet for this article.
June 1977: Revista do Hospital Das Clínicas
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