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Anterior Uveitis

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https://www.readbyqxmd.com/read/28340205/ocular-involvement-in-patients-with-spondyloarthritis
#1
Ana Beatriz Santos Bacchiega, Gustavo Guimarães Moreira Balbi, Manuella Lima Gomes Ochtrop, Francisco Assis de Andrade, Roger Abramino Levy, Xenofon Baraliakos
Ocular inflammatory diseases can present as isolated conditions but also as part of systemic inflammatory diseases. Anterior uveitis is closely related to SpA and shares the common genetic background of HLA-B27. Other ocular manifestations, such as episcleritis and scleritis, may also occur, although less frequently. Therefore, ocular involvement has been included as one of the important clinical features of SpA in the recently published classification criteria for axial and peripheral disease. However, there are a wide variety of aetiologies for ocular diseases and this must be considered in assessment of SpA...
March 18, 2017: Rheumatology
https://www.readbyqxmd.com/read/28331205/therapy-monitoring-risk-of-anterior-uveitis-in-as
#2
Jessica McHugh
No abstract text is available yet for this article.
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28328558/dacryoadenitis-as-the-initial-presentation-of-a-natural-killer-t-cell-lymphoma
#3
Juan C Jiménez-Pérez, Frederick A Jakobiec, Fouad R Zakka, Michael K Yoon
Primary orbital natural killer T-cell lymphoma (NKTCL) is a rare condition with only a few published cases in the literature. Over 1 month, an 81-year-old man developed progressive left periocular inflammation unresponsive to treatment. Clinical examination and imaging studies demonstrated a left lacrimal gland enlargement. Bilateral anterior uveitis and erythematous nontender cutaneous lesions were also found. Biopsies of the skin and lacrimal gland on the back revealed histopathologic and immunohistochemical findings confirming Epstein-Barr virus-positive NKTCL...
March 21, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28327059/association-between-non-infectious-uveitis-and-thyroid-dysfunction-a-case-control-study
#4
Amir Rosenblatt, Hussein Zaitoon, Zohar Habot-Wilner
BACKGROUND: Several reports suggested a relation between uveitis and thyroid disease or dysfunction. However, no study has investigated the association between uveitis and thyroid dysfunction. The purpose of this study was to compare the prevalence of thyroid dysfunction in patients with and without non-infectious uveitis. METHODS: This was a retrospective, case-control study. RESULTS: Two hundred thirty-five non-infectious uveitis patients (uveitis group) and 600 controls (control group) were included in the study, of whom 492 (58...
March 22, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28323505/pattern-of-uveitis-in-a-referral-hospital-in-bangladesh
#5
Zahedur Rahman, Ziaul Ahsan, Niaz Abdur Rahman, Parthopratim Dutta Majumder
PURPOSE: To report the pattern of uveitis in a tertiary eye care center in Bangladesh. METHODS: Retrospective analysis of all uveitis cases visiting uveitis clinic of Bangladesh Eye Hospital between January, 2009 and April, 2015. RESULTS: In total, 652 patients (mean age 32.3 years, female 47.8%) were included in the study. Uveitis was bilateral in 42.6% of cases. Anterior uveitis was the most common (39.2%) case, closely followed by intermediate uveitis (22...
March 21, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28318708/-high-irradiance-accelerated-corneal-collagen-crosslinking-for-the-treatment-of-keratoconus-a-retrospective-study
#6
N Moineau, L Sauvan, J Benichou, G Ho Wang Yin, L Hoffart
PURPOSE: To evaluate the safety and efficacy of accelerated corneal collagen crosslinking on stabilization of progressive keratoconus. MATERIALS AND METHODS: This was a retrospective study from March 2013 to March 2015. Patients with progressive keratoconus who underwent accelerated corneal collagen crosslinking were included. Visual acuity with and without correction, biomicroscopy, corneal elevation topography (maximum and mean keratometry values, minimum pachymetry, densitometry) and side effects were recorded at baseline and at 1, 3 and 6 months (M)...
March 15, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28318350/clinical-course-and-outcomes-of-pediatric-tubercular-uveitis-in-north-india
#7
Savleen Kaur, Kanika Aggarwal, Aniruddha Agarwal, Deepti Suri, Anju Gupta, Ramandeep Singh, Reema Bansal, Surjit Singh, Nirbhai Singh, Amod Gupta, Vishali Gupta
PURPOSE: To analyze the clinical features, course, management, and outcomes of tubercular (TB) uveitis in the pediatric population and assess the response to anti-tubercular therapy (ATT). METHODS: Hospital records of children (≤16 years) from a large tertiary-care institute between January 2001 and December 2015 were reviewed. RESULTS: A total of 32 children (mean age: 10.7 ± 4.27 years; range 2-16) were diagnosed with TB-associated uveitis...
March 20, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28318342/pattern-of-uveitic-hypotony-in-a-tertiary-eye-hospital-in-india
#8
Parthopratim Dutta Majumder, Keerthi Burugupalli, Nitin Kumar Menia, Sudha K Ganesh, Jyotirmay Biswas
PURPOSE: To report pattern of uveitic patients with hypotony in Indian population. METHODS: Retrospective medical record review of 30 eyes of 21 consecutive patients with uveitic hypotony. Patient demographics, ocular findings and systemic association were recorded. RESULTS: Mean age of the patients was 29.5 years (range 7-71 years) and 80.9%(17 patients) were below the age of 40 years. Most common complaint associated with the development of hypotony was diminution of vision (26 eyes; 86...
March 20, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28306365/ulcerative-granuloma-of-the-eyelid-as-the-initial-manifestation-of-granulomatosis-with-polyangiitis-wegener-s-granulomatosis-a-case-report
#9
Helena Brosa Morros, Olaia Subirà, Montse Gomà Gàllego, Maria José Paúles Villar, Ferran Mascaró Zamora, Maravillas Abia Serrano
A 56-year-old-man presented a 2-month history of chalazion in the eyelids without response to treatment and with an inconclusive biopsy. Laboratory results confirmed the presence of Enterobacter cloacae and Streptococcus gordonii infection. Despite appropriate intravenous antibiotic treatment, clinical worsening was observed. Radical surgical excision and total tarsorrhaphy were performed. Following treatment, the patient was asymptomatic for 6 weeks until he developed acute renal failure, generalised arthralgia, acute hypertensive anterior uveitis, and dacryoadenitis...
March 17, 2017: Orbit
https://www.readbyqxmd.com/read/28302454/craniofacial-fibrous-dysplasia-a-10-case-series
#10
A Couturier, O Aumaître, L Gilain, B Jean, T Mom, M André
OBJECTIVES: Fibrous dysplasia of bone is a rare sporadic benign congenital condition in which normal cancellous bone is replaced by fibro-osseous tissue with immature osteogenesis. Sarcomatous transformation is exceptional. Lesions may involve one bone (monostotic) or several (polyostotic). Fibrous dysplasia may be associated with café-au-lait skin macules and endocrinopathy in McCune-Albright syndrome, or with myxoma in Mazabraud's syndrome. METHODS: We report ten cases of patients followed up for craniofacial fibrous dysplasia in our center between 2010 and 2015...
March 14, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28293699/-lues-ocular-syphilis
#11
T Neß
Ocular syphilis is not a new issue but due to increasing rates of new cases is now a contemporary issue. The clinical features are unspecific and can be manifested as all forms of ocular inflammation. Unspecific anterior uveitis is the most frequent ocular involvement; however, typical distinctive patterns are superficial white preretinal precipitates within a panuveitis and acute syphilitic posterior placoid chorioretinitis. The diagnosis should be confirmed by serological tests. Treatment is based on parenteral administration of penicillin...
March 14, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28291196/-cytokine-profile-changes-in-children-with-juvenile-idiopathic-arthritis-associated-uveitis
#12
E A Drozdova, E V Yadykina, E A Mezentseva, K V Nikushkina
AIM: to identify the differences between serum cytokine profiles in juvenile idiopathic arthritis (JIA) with or without uveal tract inflammation. MATERIAL AND METHODS: Serum cytokine profiles were studied in two groups of patients: 20 children with JIA and JIA-associated uveitis and 33 children, who had no signs of uveitis under basic therapy for their JIA. All the patients showed drug remission of articular syndrome. Inflammation of the choroid took the form of chronic anterior uveitis...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28283043/birmingham-beh%C3%A3-et-s-service-classification-of-disease-and-application-of-the-2014-international-criteria-for-beh%C3%A3-et-s-disease-icbd-to-a-uk-cohort
#13
Tim Blake, Luke Pickup, David Carruthers, Erika Marie Damato, Alastair Denniston, John Hamburger, Claire Maxton, Debbie Mitton, Philip I Murray, Peter Nightingale, Ana Poveda-Gallego, Andrea Richards, Andrew Whallett, Deva Situnayake
BACKGROUND: This study reports on the analysis of the application and diagnostic predictability of the revised 2014 ICBD criteria in an unselected cohort of UK patients, and the ensuing organ associations and patterns of disease. METHODS: A retrospective cohort study was conducted using a database of electronic medical records. Three categories were recognised: clinically defined BD, incomplete BD and rejected diagnoses of BD. We applied the ISG 1990 and ICBD 2014 classification criteria to these subgroups to validate diagnostic accuracy against the multidisciplinary assessment...
March 11, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28282736/ocular-inflammation-associated-with-polymyalgia-rheumatica-without-concomitant-giant-cell-arteritis-a-report-of-three-cases
#14
Takahiro Arai, Rie Tanaka, Toshikatsu Kaburaki
PURPOSE: We report three cases of ocular inflammation and polymyalgia rheumatica without concomitant giant-cell arteritis. METHODS: Report of three cases. RESULTS: Polymyalgia rheumatica onset was at a mean age of 66.7 years, and ocular inflammation, which developed 7-21 months later, was bilateral in all patients. Ocular inflammation presented as episcleritis, scleritis, or anterior uveitis, and it emerged during the tapering of low-dose prednisolone prescribed for polymyalgia rheumatica in all patients...
February 22, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28278321/in-vivo-bioluminescence-imaging-for-longitudinal-monitoring-of-inflammation-in-animal-models-of-uveitis
#15
Michal B Gutowski, Leslie Wilson, Russell N Van Gelder, Kathryn L Pepple
Purpose: We develop a quantitative bioluminescence assay for in vivo longitudinal monitoring of inflammation in animal models of uveitis. Methods: Three models of experimental uveitis were induced in C57BL/6 albino mice: primed mycobacterial uveitis (PMU), endotoxin-induced uveitis (EIU), and experimental autoimmune uveitis (EAU). Intraperitoneal injection of luminol sodium salt, which emits light when oxidized, provided the bioluminescence substrate. Bioluminescence images were captured by a PerkinElmer In Vivo Imaging System (IVIS) Spectrum and total bioluminescence was analyzed using Living Image software...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28261099/curcumin-a-potential-therapeutic-candidate-for-anterior-segment-eye-diseases-a-review
#16
REVIEW
Xiu-Fen Liu, Ji-Long Hao, Tian Xie, Nour Jama Mukhtar, Wiley Zhang, Tayyab Hamid Malik, Cheng-Wei Lu, Dan-Dan Zhou
Curcumin, the major curcuminoid of the turmeric, has been extensively used in many countries since ancient time for preventing and/or treating a multitude of diseases. This review is to illustrate the researches on the properties of curcumin and its potential therapeutic efficacy in major anterior segment eye diseases. The bio-medical potential of curcumin is restricted because of its low solubility and digestive bioavailability. This review will discuss promising research in improving curcumin bioavailability through structural modification...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28260142/the-spectrum-of-vogt-koyanagi-harada-disease-in-iran
#17
Alireza Hedayatfar, Seyedeh Maryam Hosseini, Nasser Karimi, Khalil Ghasemi Falavarjani, Negin Badie, Mahsa Zameni, Masoud Soheilian
PURPOSE: To report the spectrum of Vogt-Koyanagi-Harada (VKH) disease in Persians. MATERIALS AND METHODS: This is a retrospective chart review of patients diagnosed with VKH disease at four referral centers in Iran. Patients' demographics, ocular and extraocular manifestations, treatment modalities, complications, and visual outcomes were collected and analyzed. RESULTS: Eighty-eight patients with a mean age of 32.1 ± 12.6 years (range 7-79 years) were studied...
March 4, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28257832/risk-factors-for-the-development-of-cataract-in-children-with-uveitis
#18
Tamar Blum-Hareuveni, Sophie Seguin-Greenstein, Michal Kramer, Guy Hareuveni, Yael Sharon, Ronit Friling, Lazha Sharief, Sue Lightman, Oren Tomkins-Netzer
PURPOSE: To determine the risk factors for the development of cataract in children with uveitis of any etiology. DESIGN: Cohort study METHODS: 247 eyes of 140 children with uveitis were evaluated for the development of vision affecting cataract. Demographic, clinical and treatment data were collected between the time of presentation and the first instance cataract was recorded or findings at final follow-up. Main outcome measures included prevalence of cataract and distribution by type of uveitis, incidence of new onset cataract time to cataract development and risk factors for the development of cataract...
February 28, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28257383/conjunctival-tattoo-with-inadvertent-globe-penetration-and-associated-complications
#19
Natasha Ferreira Santos da Cruz, Kátia Santana Santos, Michelle de Lima Farah, Sergio Felberg
PURPOSE: To report a case of conjunctival tattooing for cosmetic purposes with inadvertent globe penetration resulting in severe inflammation, capsular lens opacity, and secondary glaucoma. METHODS: Case report. RESULTS: A 25-year-old woman experienced severe ocular pain and decreased vision in the left eye after conjunctival tattooing for cosmetic purposes on the previous day. Slit-lamp examination revealed black deposits over the conjunctiva, corneal endothelium, anterior chamber angle, iris, and anterior capsular lens due to the tattooing pigment...
March 1, 2017: Cornea
https://www.readbyqxmd.com/read/28254789/tumour-necrosis-factor-inhibitor-treatment-and-occurrence-of-anterior-uveitis-in-ankylosing-spondylitis-results-from-the-swedish-biologics-register
#20
Elisabeth Lie, Ulf Lindström, Tatiana Zverkova-Sandström, Inge C Olsen, Helena Forsblad-d'Elia, Johan Askling, Meliha C Kapetanovic, Lars Erik Kristensen, Lennart T H Jacobsson
OBJECTIVES: Tumour necrosis factor-α inhibitor (TNFi) treatment has been shown to reduce the rates of anterior uveitis (AU) in patients with ankylosing spondylitis (AS). Our objective was to compare the effect of adalimumab (ADA), etanercept (ETN) and infliximab (IFX) on AU occurrence in AS, using real-world data. METHODS: Patients with AS starting ADA, ETN or IFX as their first TNFi from January 2003 to December 2010 were extracted from the Swedish Rheumatology Quality Register...
March 2, 2017: Annals of the Rheumatic Diseases
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