keyword
https://read.qxmd.com/read/38532849/multimodal-imaging-in-a-case-of-presumed-secondary-vitreoretinal-lymphoma-presenting-with-inner-retina-and-optic-nerve-head-infiltration
#1
Emily S Levine, Nikhil N Batra
PURPOSE: To report the findings supported by multimodal imaging in a case of secondary vitreoretinal lymphoma presenting with inner retina and optic nerve head infiltration. OBSERVATIONS: A 64-year-old man with systemic diffuse large B-cell lymphoma presented with reduced visual acuity. Moderate anterior chamber and vitreous cell were present. Fundus exam showed bilateral disc edema and diffuse opaque macular infiltrates with a pseudo cherry-red spot in the left eye...
June 2024: American Journal of Ophthalmology Case Reports
https://read.qxmd.com/read/38527189/demographic-and-clinical-profile-of-pediatric-uveitis-in-delta-region-egypt
#2
JOURNAL ARTICLE
Nagwa Hussein Abdelmageed, Anas Adi, Samy Abo El-Khair, Maha Shahin, Doaa Mosad Mosa, Dalia Sabry, Amgad El Nokrashy
PURPOSE: Pediatric uveitis poses unique challenges, characterized by difficulties in performing comprehensive examinations, potential delays in diagnosis, and a heightened risk of ocular complications. This study evaluate the etiologic and clinical characteristics of uveitis in children presenting to the Mansoura Ophthalmic Center, Mansoura, Egypt. METHODS: A cross-sectional observational study was undertaken involving children diagnosed with uveitis attending the uveitis outpatient clinic at Mansoura University Ophthalmic Center...
March 25, 2024: Ocular Immunology and Inflammation
https://read.qxmd.com/read/38524579/cutaneous-leukocytoklastic-vasculitis-in-a-patient-with-ankylosing-spondylitis-a-case-report
#3
Yida Xing, Chengjun Zhuang, Qian Yu, Changyan Liu, Mingxi Xu, Lin Zhao, Xiaodan Kong
Extra-articular manifestations (EAMs) in ankylosing spondylitis (AS) are common and most extra-articular manifestations such as acute iritis and inflammatory bowel disease are positively correlated with disease activity of AS. Vasculitis is an extra-articular manifestation of AS. However cutaneous leukocytoclastic vasculitis (CLV) is uncommon in AS patients. In this article, we report a case of a 66-year-old female patient who has had AS for long time. Although the patient's articular manifestations were stable, the aortic aneurysm and CLV continued to occur sequentially...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38519851/intraocular-parafilaria-bovicola-infection-and-surgical-removal-in-a-mixed-breed-heifer
#4
A K Shukla, A Contadini, K Kazmir-Lysak, M Schnyder, C Gerspach, S A Pot
An approximately 1.5-year-old mixed breed heifer was presented for evaluation and treatment due to ocular pain affecting the right eye secondary to a live nematode within the anterior chamber. Ophthalmic examination revealed marked blepharospasm, evidence of chronic keratitis, uveitis, and a single, white, approximately 2.5 cm long, 0.5 mm thick, living parasite. The heifer underwent general anesthesia, and the parasite was removed using passive aqueous humor outflow following a stab incision into the anterior chamber...
March 22, 2024: Veterinary Ophthalmology
https://read.qxmd.com/read/38519714/diagnostic-and-therapeutic-challenges-in-acute-retinal-necrosis-an-update
#5
REVIEW
Dimitrios Kalogeropoulos, Farid Afshar, Chris Kalogeropoulos, Georgios Vartholomatos, Andrew John Lotery
Acute retinal necrosis (ARN) is a rare but severe ophthalmic pathology defined by panuveitis, retinal necrosis, and high rates of retinal detachment. ARN may lead to poor visual outcomes even if promptly diagnosed and treated. ARN may present with a wide spectrum of clinical findings compatible with panuveitis including anterior uveitis, scleritis, vitritis, necrotizing retinitis, occlusive vasculitis, and optic disc edema. The American Uveitis Society introduced clinical criteria in 1994 for the diagnosis of ARN, while more recent criteria have been proposed by the Standardization of Uveitis Nomenclature (SUN) Working Group and the Japanese ARN Study Group...
March 22, 2024: Eye
https://read.qxmd.com/read/38518991/diagnostic-utility-of-quantiferon-gold-testing-in-patients-with-ocular-inflammation-in-a-low-endemic-tuberculosis-region
#6
JOURNAL ARTICLE
Julia Xia, Alan G Palestine, Amit K Reddy
PURPOSE: To evaluate the diagnostic value of QuantiFERON Gold (QFT-G) testing for ocular inflammation in a low prevalence tuberculosis (TB) area. DESIGN: Diagnostic utility analysis. METHODS: A review was performed for all uveitis patients who underwent QFT-G testing at the University of Colorado Eye Center from 2009-2022. Records were reviewed to assess QFT-G positivity rate and to identify which patients were tested for diagnostic purposes, defined as meeting the Standardization of Uveitis Nomenclature (SUN) criteria for tubercular uveitis (TBU): anterior uveitis with iris nodules, serpiginous-like choroiditis, choroidal nodule resembling a tuberculoma, multifocal choroiditis, or occlusive retinal vasculitis...
March 20, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38517389/viral-anterior-uveitis-differences-in-retinal-vessel-area-density-between-the-affected-and-non-affected-eye-using-optical-coherence-tomography-angiography
#7
JOURNAL ARTICLE
Anna-Karina B Maier, Daniel Mandrossa, Emanuel Reitemeyer, Sibylle Winterhalter, Anne Rübsam, Uwe Pleyer
PURPOSE: To investigate differences in the retinal vessel area density (VAD) on optical coherence tomography angiography (OCTA) between eyes with unilateral herpetic viral anterior uveitis (VAU) (herpes-simplex virus (HSV) and varicella-zoster virus (VZV)) and the non-affected fellow eye. METHODS: In this monocentric, observational, prospective case series we analyzed the VAD of the macula, optic disc, and peripapillary region in affected and non-affected eyes of 22 patients with HSV-positive and 22 patients with VZV-positive VAU using OCTA...
March 22, 2024: Ocular Immunology and Inflammation
https://read.qxmd.com/read/38505579/rosai-dorfman-disease-as-chronic-bilateral-granulomatous-anterior-uveitis-a-case-report
#8
Yaninsiri Ngathaweesuk, Chaisiri Jumroendararasame
Rosai-Dorfman disease is a rare non-Langerhans cell histiocytosis disorder, also known as sinus histiocytosis, with massive lymphadenopathy. Rosai-Dorfman disease is classified into nodal and extranodal diseases. Ocular involvement is one of the common extranodal manifestations; however, uveitis manifestation is infrequent. We reported an interesting Rosai-Dorfman disease patient who presented with chronic bilateral granulomatous anterior uveitis with disc hyperemia and cystoid macular edema. She was a 60-year-old Thai female who had abnormal skin nodules on her back after multiple recurrent chronic anterior uveitis...
2024: SAGE Open Medical Case Reports
https://read.qxmd.com/read/38482096/reactive-arthritis-after-mpox-vaccination
#9
Indira Acharya, Lanaya W Smith, Chandralekha Banerjee, Lyn M Camire, Radhika Vij
Autoimmune inflammatory reaction after vaccination is a rare clinical entity. Reactive arthritis has been described after various vaccinations, but not after mpox vaccination. Here we present a case of recently diagnosed reactive arthritis after mpox vaccination that presented in the context of unrelenting fever and diarrhea complicated by migratory arthritis and anterior uveitis. We have reported this case to the Vaccine Adverse Event Reporting System (VAERS).
2024: Journal of Community Hospital Internal Medicine Perspectives
https://read.qxmd.com/read/38475831/investigation-of-the-acute-pathogenesis-of-spondyloarthritis-hla-b27-associated-anterior-uveitis-based-on-genome-wide-association-analysis-and-single-cell-transcriptomics
#10
JOURNAL ARTICLE
Shuming Chen, Weidi Huang, Qiaoqian Wan, Zichun Tang, Xie Li, Fang Zeng, Shuyan Zheng, Zhuo Li, Xiao Liu
BACKGROUND: Patients with spondyloarthritis (SpA)/HLA-B27-associated acute anterior uveitis (AAU) experience recurring acute flares, which pose significant visual and financial challenges. Despite established links between SpA and HLA-B27-associated AAU, the exact mechanism involved remains unclear, and further understanding is needed for effective prevention and treatment. METHODS: To investigate the acute pathogenesis of SpA/HLA-B27-associated AAU, Mendelian randomization (MR) and single-cell transcriptomic analyses were employed...
March 12, 2024: Journal of Translational Medicine
https://read.qxmd.com/read/38472380/ultrawide-field-fluorescein-angiography-features-in-patients-with-anterior-uveitis
#11
JOURNAL ARTICLE
Nam V Nguyen, Enny Oyeniran, Alexander Zeleny, Michelle Chen, Noha A Sherif, Eleni Konstantinou, Susan Vitale, H Nida Sen, Shilpa Kodati
PURPOSE: To evaluate the utility of ultrawide-field fluorescein angiography (UWFFA) in patients with anterior uveitis by investigating the detection of retinal vascular leakage (RVL) and the subsequent implications on disease diagnosis and management. STUDY DESIGN/MATERIALS AND METHODS: Patients, who were referred to the National Eye Institute (NEI) for evaluation of anterior uveitis and underwent UWFFA imaging at the initial visit, were included in this study. The electronic medical records of eligible patients were reviewed...
March 12, 2024: Eye
https://read.qxmd.com/read/38470999/uveitic-flare-ups-after-gonioscopy-assisted-transluminal-trabeculotomy-gatt-in-patients-with-uveitic-glaucoma
#12
JOURNAL ARTICLE
Raz Gepstein, Tamar Laytman Klein, Liron Naftali Ben Haim, Avner Belkin
PURPOSE: To assess the risk of gonioscopy-assisted transluminal trabeculotomy (GATT) inducing an uveitic flare-up in patients with uveitic glaucoma (UG). METHODS: This retrospective study included consecutive UG patients who underwent GATT at a single medical center between June 2020 and September 2022. The main outcome measure was the occurrence of a surgery-related uveitic complication defined as either an uveitic flare-up defined by the Standardization of Uveitis Nomenclature (SUN) criteria, or the appearance of cystoid macular edema (CME) from 2 weeks to 3 months after surgery...
March 12, 2024: Ocular Immunology and Inflammation
https://read.qxmd.com/read/38470990/pretreatment-ocular-blood-flow-and-retinal-oxygen-metabolism-in%C3%A2-the-acute-uveitic-phase-is-associated-with-final-outcome-in-vogt-koyanagi-harada-disease
#13
JOURNAL ARTICLE
Ahmed M Abu El-Asrar, Abdulrahman F AlBloushi, Abdullah Alzubaidi, Priscilla W Gikandi, Einar Stefánsson
PURPOSE: To investigate the association between pretreatment blood flow velocity in the choroid and optic nerve head (ONH) and retinal oxygen metabolism in the acute uveitic phase and the development of 'sunset glow fundus' in Vogt-Koyanagi-Harada (VKH) disease. METHODS: Retrospective analysis of 41 patients (82 eyes). Laser speckle flowgraphy and retinal oximetry measurements were performed at the presentation. The main outcome measure was the development of 'sunset glow fundus'...
March 12, 2024: Acta Ophthalmologica
https://read.qxmd.com/read/38462376/-dislocation-into-the-anterior-chamber-and-spontaneous-repositioning-of-a-dexamethasone-intravitreal-implant-a-case-report
#14
JOURNAL ARTICLE
L L Liang, S Ju, Z H Cui
A 61-year-old male patient presented with blurred vision in the right eye for 1 day. The patient had previously undergone phacoemulsification with intraocular lens implantation (10 years ago) and intravitreal implantation of dexamethasone (due to uveitis) in the eye. There was edema in the inferior cornea, along with Descemet membrane folds. The rod-shaped dexamethasone implant was visible in the inferior anterior chamber. Without pupil dilation, the patient was asked to keep a supine position and avoid head tilting for 1 day...
March 11, 2024: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://read.qxmd.com/read/38455876/developing-international-classification-of-disease-code-definitions-for-the-study-of-enteric-infection-sequelae-in-canada
#15
JOURNAL ARTICLE
Eleni Galanis, Azita Goshtasebi, Yuen Wai Hung, Jonathan Chan, Douglas Matsell, Kristine Chapman, Gilaad Kaplan, David Patrick, Bei Yuan Zhang, Marsha Taylor, Dimitra Panagiotoglou, Shannon Majowicz
BACKGROUND: Enteric infections and their chronic sequelae are a major cause of disability and death. Despite the increasing use of administrative health data in measuring the burden of chronic diseases in the population, there is a lack of validated International Classification of Disease (ICD) code-based case definitions, particularly in the Canadian context. Our objective was to validate ICD code definitions for sequelae of enteric infections in Canada: acute kidney injury (AKI); hemolytic uremic syndrome (HUS); thrombotic thrombocytopenic purpura (TTP); Guillain-Barré syndrome/Miller-Fisher syndrome (GBS/MFS); chronic inflammatory demyelinating polyneuropathy (CIDP); ankylosing spondylitis (AS); reactive arthritis; anterior uveitis; Crohn's disease, ulcerative colitis, celiac disease, erythema nodosum (EN); neonatal listeriosis (NL); and Graves' disease (GD)...
August 1, 2023: Canada Communicable Disease Report
https://read.qxmd.com/read/38454869/an-analysis-of-the-clinical-and-investigative-profile-of-uveitis-in-the-elderly-first-case-series-from-india
#16
JOURNAL ARTICLE
Kowsigan Magesan, Arshee Ahmed, Amala E George, Sudha K Ganesh, Jyotirmay Biswas, Parthopratim Dutta Majumder
PURPOSE: To evaluate the spectrum of uveitis occurring after 60 years of age in elderly patients who presented to a tertiary care eye center in India. METHODS: Retrospective study of patients who visited a tertiary eye care institute between January 2010 and July 2020. RESULT: Eighty-seven patients developed uveitis after 60 years, with only 44.8% having sufficient follow-up documentation and were included in the final analysis. The median age of these patients was 64 (IQR: 62-70) years, and 69% of them were male...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454843/clinical-and-demographic-profile-of-herpes-zoster-ophthalmicus-a-hospital-based-study-of-1752-indian-patients
#17
JOURNAL ARTICLE
Anubha Rathi, Anthony V Das, Muralidhar Ramappa
PURPOSE: To describe the clinical and demographic profile of herpes zoster ophthalmicus (HZO) in patients presenting to a multitier ophthalmology hospital network in India. METHODS: Cross-sectional hospital-based study included 3,004,470 new patients between August 2010 and October 2021. Patients with a clinical diagnosis of HZO in at least one eye were included. Data were collected using an electronic medical record system. RESULTS: In total, 1,752 (0...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454387/retinochoroiditis-secondary-to-rickettsia-typhi-infection-a-case-report
#18
JOURNAL ARTICLE
Joanne Makhoul, Yael Ben-Arie-Weintrob, Dror Ben Ephraim Noyman
BACKGROUND: To report a case of unusual presentation of retinochoroiditis caused by Rickettsia typhi in a patient without prior uveitis. CASE PRESENTATION: In this case, we describe a 24-year-old male soldier with no previous eye disease, who was referred to our ophthalmology department due to bilateral retinochoroiditis and vitritis. The patient initially presented with a paracentral scotoma in his right eye persisting for 7 days and scattered dark spots in his left eye for 2 days in June 2023...
March 7, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38454194/factors-associated-with-acute-anterior-uveitis-history-in-patients-with-axial-spondyloarthritis-results-of-a-longitudinal-study
#19
JOURNAL ARTICLE
Haluk Cinakli, Elif Durak Ediboglu, Dilek Solmaz, Servet Akar
BACKGROUNDS: Acute anterior uveitis (AAU) is the most common extra-musculoskeletal manifestation in axial spondyloarthritis (axSpA). OBJECTIVES: The aim of the study is to evaluate the factors associated with AAU attacks in patients with axSpA during a 36-month follow-up period. METHODS: In total, 469 patients with axSpA were included in this observational study. Demographic data, clinical characteristics, disease activity measurements, and treatment patterns were compared between patients with and without a history of AAU...
March 2024: International Journal of Rheumatic Diseases
https://read.qxmd.com/read/38446198/epidemiology-clinical-features-and-classification-of-3-404-patients-with-uveitis-colombian-uveitis-multicenter-study-col-uvea
#20
JOURNAL ARTICLE
Alejandra de-la-Torre, Germán Mejía-Salgado, Carlos Cifuentes-González, William Rojas-Carabali, Miguel Cuevas, Sandra García, Carlos M Rangel, Claudia Durán, Diana Isabel Pachón-Suárez, Andrés Bustamante-Arias
PURPOSE: To describe the epidemiology, clinical features, and classification of uveitis in a large cohort of Colombian patients. METHODS: Data were collected from seven ophthalmological referral centers in the four main cities in Colombia. The study included patients with a confirmed diagnosis of uveitis from January 2010 to December 2022. Information on demographics, ophthalmic examination findings, uveitis classification, and etiology was recorded. RESULTS: The study reviewed 3,404 clinical records of patients with uveitis...
March 6, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
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