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https://www.readbyqxmd.com/read/29356181/guideline-compliant-prescription-of-biologicals-and-possible-barriers-in-dermatological-practices-in-bavaria
#1
M Schielein, L Tizek, M Rotter, A Konstantinow, T Biedermann, A Zink
INTRODUCTION: Psoriasis and urticaria are chronic inflammatory skin diseases, which account for a substantial socio-economic burden and severely affect patients' quality of life. According to the respective German guidelines, biologicals can be used for the treatment of severe forms of these diseases. However, only a minority of patients receive this advised treatment. OBJECTIVE: To analyse the prescription of biologicals according to German national guidelines for psoriasis and chronic spontaneous urticaria and to assess possible barriers to prescription...
January 22, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29355431/risk-factors-and-direct-medical-cost-of-early-versus-late-unplanned-readmissions-among-diabetes-patients-at-a-tertiary-hospital-in-singapore
#2
May Ee Png, Joanne Yoong, Cynthia Chen, Chuen Seng Tan, E Shyong Tai, Eric Yh Khoo, Hwee Lin Wee
OBJECTIVE: To examine the risk factors and direct medical cost associated with early (≤30 days) versus late (31-180 days) unplanned readmissions among patients with type 2 diabetes in Singapore. METHODS: Risk factors and its associated cost among diabetes patients were investigated using electronic medical records from a local tertiary care hospital from 2010 to 2012. Multivariable logistic regression was used to identify risk factors associated with early and late unplanned readmissions while a generalized linear model was used to estimate the direct medical cost...
January 22, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29354743/national-outcomes-following-single-level-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion
#3
Jamal Shillingford, Joseph Laratta, Nathan Hardy, Comron Saifi, Joseph Lombardi, Andrew J Pugely, Ronald A Lehman, K Daniel Riew
Background: To compare the differences in the thirty-day postoperative outcomes between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF). Methods: Patients undergoing primary single-level ACDF and CDA from 2010-2014 were identified by unique Current Procedural Terminology (CPT) codes within the American College of Surgeon's National Surgical Quality Improvement Program (NSQIP) database. Primary outcomes included surgical and medical complications, length of hospital stay (LOS), unplanned readmission, return to operating room, and mortality all occurring within 30 days of the initial procedure...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29354671/recruiting-patients-after-hospital-discharge-for-acute-exacerbation-of-copd-challenges-and-lessons-learned
#4
Gary T Ferguson, Bonnie Beck, Emmanuelle Clerisme-Beaty, Dacheng Liu, Byron M Thomashow, Robert A Wise, Richard ZuWallack, Barry J Make
Background: Hospitalizations for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are associated with increased mortality and decreased quality of life. Replicate hospital discharge studies were initiated to examine efficacy and safety of once-daily tiotropium HandiHaler® versus placebo, in addition to usual care, in patients discharged from the hospital after an AECOPD. Methods: Both studies were randomized, placebo-controlled, double-blind, parallel-group, multicenter, with inclusion/exclusion criteria providing a diverse COPD patient cohort hospitalized for ≤14 days with AECOPD...
August 10, 2017: Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation
https://www.readbyqxmd.com/read/29354324/comparison-of-patient-outcome-measures-between-a-traditional-teaching-hospitalist-service-and-a-non-teaching-hospitalist-service-at-an-academic-children-s-hospital
#5
Tony R Tarchichi, Jessica Garrison, Kwonho Jeong, Anthony Fabio
Background and objectives: Inpatient pediatric care is increasingly provided by pediatric hospitalists. This, in addition to changes in resident duty hour restrictions, has led to the creation of new models of care for inpatient pediatric patients. The objective of this study was to compare traditional outcome measures between a pediatric hospitalist-only service and a more traditional academic service in which care was provided by pediatric hospitalists, residents, and medical students...
December 2017: Pediatrics & Therapeutics: Current Research
https://www.readbyqxmd.com/read/29354198/the-virtual-hallway-consult-as-an-effective-means-of-continuing-professional-development-in-physiatry
#6
Karen Ethans, Tim Deutscher, Mayur Nankar
Background: A personal learning project (PLP) is an accredited form of Continuing Professional Development (CPD) in Canada, and is a self-initiated learning activity that is stimulated by a question, issue or dilemma in one's professional practice. Many complex cases or issues have no answers that are readily available. Many physicians rely day to day on other physician colleagues that they may consult in their institution. Given the paucity of same specialty Physical Medicine and Rehabilitation colleagues in Canadian centres, the idea of Virtual Spinal Cord Injury (SCI) Hallway germinated, to provide a simple tool to extend our hallways to reach colleagues with similar interests across the country...
December 2017: Canadian Medical Education Journal
https://www.readbyqxmd.com/read/29354156/lower-limbs-heterometry-correction-in-patients-with-osteoporosis-and-increased-risk-of-falls
#7
Elisa Pratelli, Angelo Alito, Claudio Zanella, Laura Busi, Giuseppe Mangone, Matteo Scarselli, Pietro Pasquetti
Osteoporotic fractures are associated with a significant increase in morbidity, mortality and medical costs. There is also a strong link between fractures and increased mortality. Among effective measures for the prevention of falls, instability treatment surely plays a crucial role. Several factors contribute to instability, many of which are ageing-related: visual spatial deficit, strength reduction, weight imbalance with COP lateralization sometimes favoured by LLD (leg length discrepancy). It seems useful to detect an heterometry which could be corrected, if present...
September 2017: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/29353546/who-starts-the-conversation-and-who-receives-preexposure-prophylaxis-prep-a-brief-online-survey-of-medical-providers-prep-practices
#8
Leah M Adams, Benjamin H Balderson, Kathy Brown, Staci E Bush, Bruce J Packett
Uptake of preexposure prophylaxis (PrEP) has been slow, but is increasing. Although PrEP is indicated for many patients, it has been concentrated among men who have sex with men (MSM). Awareness of PrEP is limited among non-MSM individuals, and among some MSM. As such, individuals at risk for HIV who are unaware of PrEP must rely on their medical providers to initiate conversations about PrEP. Members of a national professional organization of HIV specialists with prescribing privileges, including physicians, nurse practitioners, and physician assistants, participated in an online survey ( n = 342) to characterize their PrEP prescribing behaviors and the demographic membership of their PrEP patients...
January 1, 2018: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29353536/a-progressive-three-phase-innovation-to-medical-education-in-the-united-states
#9
Cory M Pfeifer
The practice of medicine has changed greatly over the past 100 years, yet the structure of undergraduate medical education has evolved very little. Many schools have modified their curricula to incorporate problem-based learning and organ systems-based curricula, but few schools have adequately addressed rising tuition costs. Undergraduate medical education has become cost-prohibitive for students interested in primary care. In the meanwhile, the concept of a separate dedicated intern year is outdated and mired in waste despite remaining a requirement for several hospital-based and surgical specialties...
December 2018: Medical Education Online
https://www.readbyqxmd.com/read/29353499/-who-should-decide-at-the-end-of-life-international-practice-of-advance-care-planning-and-possibilities-for-adaptation-in-hungary
#10
Csilla Busa, Judit Zeller, Ágnes Csikós
At the advanced stage of serious illness, end-of-life decisions need to be made. Advance care planning offers patients the right to decide on their own future care when independent decision-making is no longer possible. The most complex and effective advance care plans include patients' preferred or refused medical treatments, care-related wishes, and individual values as well. Advance care planning can improve end-of-life care and contribute to higher satisfaction. It can also reduce distress in relatives and the costs of care...
January 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29353016/pyrosequencing-analysis-of-methylation-levels-of-clock-genes-in-leukocytes-from-parkinson-s-disease-patients
#11
Wei Mao, Chunsong Zhao, Hui Ding, Kuo Liang, Jinhua Xue, Piu Chan, Yanning Cai
DNA methylation of neuronal PAS domain protein 2 (NPAS2) and cryptochrome circadian clock 1 (CRY1) promoters may be associated with Parkinson's disease (PD). However, there is no simple and cost-effective method to quantify DNA methylation in these regions. Additionally, it is not clear whether DNA methylation of NPAS2 and CRY1 promoters is altered in peripheral blood of PD patients, especially newly diagnosed drug-naïve PD patients, and thus can be used as a PD biomarker. In the present study, we utilized bisulfite pyrosequencing assays to examine DNA methylation levels of six CpG sites in the NPAS2 promoter and five CpG sites in the CRY1 promoter...
January 17, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29351053/patient-variability-seldom-assessed-in-cost-effectiveness-studies
#12
Tara A Lavelle, David M Kent, Christine M Lundquist, Teja Thorat, Joshua T Cohen, John B Wong, Natalia Olchanski, Peter J Neumann
BACKGROUND: Cost-effectiveness analysis (CEA) estimates can vary substantially across patient subgroups when patient characteristics influence preferences, outcome risks, treatment effectiveness, life expectancy, or associated costs. However, no systematic review has reported the frequency of subgroup analysis in CEA, what type of heterogeneity they address, and how often heterogeneity influences whether cost-effectiveness ratios exceed or fall below conventional thresholds. METHODS: We reviewed the CEA literature cataloged in the Tufts Medical Center CEA Registry, a repository describing cost-utility analyses published through 2016...
January 1, 2018: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/29350974/use-of-simulation-based-training-to-aid-in-implementing-complex-health-technology
#13
Veffa Devers
Clinicians are adult learners in a complex environment that historically does not invest in training in a way that is conducive to these types of learners. Adult learners are independent, self-directed, and goal oriented. In today's fast-paced clinical setting, a practical need exists for nurses and clinicians to master the technology they use on a daily basis, especially as medical devices have become more interconnected and complex. As hospitals look to embrace new technologies, medical device companies must provide clinical end-user training...
January 2018: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/29350780/an-evolutionary-concept-analysis-of-futility-in-healthcare
#14
Lauren Morata
AIM: To report a concept analysis of futility in healthcare. BACKGROUND: Each member of the healthcare team, the physician, the nurse, the patient, the family and all others involved perceive futility differently. The current evidence and knowledge in regard to futility in healthcare manifest a plethora of definitions, meanings and interpretations without consensus. DESIGN: Concept analysis. DATA SOURCES: Databases searched included Medline, Cumulative Index of Nursing and Allied Health Literature, Academic Search Premier, Cochrane Database of Systematic Reviews and PsycINFO...
January 19, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29350663/effectiveness-of-a-tailored-medical-support-to-overcome-the-barriers-to-education-treatment-and-good-metabolic-control-in-children-with-type-1-diabetes-from-ethnic-minorities
#15
Brunella Iovane, Antonina Marta Cangelosi, Ilaria Bonaccini, Carla Mastrorilli, Dora Di Mauro, Valentina Fainardi, Giovanni Chiari, Marilena Maltese, Carlo Caffarelli, Maurizio Vanelli
AIM: To analyze the effectiveness of a tailored medical support to help children from ethnic minorities to achieve the same good metabolic control of autochthonous peers with type-1 diabetes (T1D). METHODS: Children <10 years of age belonging to ethnic minority (EM) families (Group 1) were compared with autochthonous peers (Group 2) who received the diagnosis of T1D in 2014-2016. The Protocol for minorities included other than the standard protocol: booklets translated in ethnic minority languages; weekly visits at home or at school; family-guides; clinic visits supported by professional interpreters...
January 16, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29349948/case-report-of-kidney-paired-donation-kpd-with-desensitization-the-strategy-and-experience-of-3-way-kpd-in-samsung-medical-center
#16
Dongkyu Oh, Eun Suk Kang, Shinae Yu, Kyoungsuk Chun, Wooseong Huh, Hye Ryoun Jang, Chan Woo Cho, Nuri Lee, Kyo Won Lee, Hyojun Park, Jae Berm Park, Sung Joo Kim
As the need for the organ donation increases, strategies to increase kidney transplantation (KT) through expanded living donation have become essential. These include kidney paired donation (KPD) programs and desensitization in incompatible transplantations. KPD enables kidney transplant candidates with incompatible living donors to join a registry with other incompatible pairs in order to find potentially compatible living donor. Positive cross match and ABO incompatible transplantation has been successfully accomplished in selective cases with several pre-conditionings...
January 29, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29349938/improved-regional-disparities-in-neonatal-care-by-government-led-policies-in-korea
#17
In Gyu Song, Seung Han Shin, Han Suk Kim
BACKGROUND: Although the number of high-risk neonates has increased in Korea, hospitals were reluctant to open or maintain neonatal intensive care unit (NICU) due to the low medical cost. Consequently, there were regional disparities in facilities, equipment, and neonatal health outcomes. For these reasons, the Korean government began to invest in neonatal care during the last decade. We identified the status of NICUs in Korea and assessed changes after the government-driven policies...
February 5, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29349708/cost-effectiveness-of-empagliflozin-for-the-treatment-of-patients-with-type-2-diabetes-mellitus-at-increased-cardiovascular-risk-in-greece
#18
George Gourzoulidis, Charalampos Tzanetakos, Ioannis Ioannidis, Apostolos Tsapas, Georgia Kourlaba, Giannis Papageorgiou, Nikos Maniadakis
BACKGROUND AND OBJECTIVE: Type 2 diabetes mellitus (T2DM) is frequently associated with co-morbidities that exacerbate cardiovascular (CV) risk. CV disease is the leading cause of death in people with diabetes across the world and accounts for approximately half the deaths in the T2DM population. Hence, the objective of present study was to evaluate the cost-effectiveness of empagliflozin, in addition to standard of care (SoC), for the treatment of adult patients with T2DM and high CV risk in Greece...
January 18, 2018: Clinical Drug Investigation
https://www.readbyqxmd.com/read/29349613/tumor-treating-fields-a-new-approach-to-glioblastoma-therapy
#19
REVIEW
Jonathan Rick, Ankush Chandra, Manish K Aghi
Glioblastoma is an aggressive brain malignancy with poor outcomes. Current standard of care involves surgery, radiotherapy and chemotherapy. Even with optimal treatment, 5-year survival rates are low. Many patients are unable to tolerate the considerable side effects that therapy involves and suffer from low quality of life. Anti-mitotic tumor treating fields have shown potential in treating glioblastoma with data suggesting that they prolong disease-free survival and overall survival. Novocure has marketed a device that generates these fields via externally placed electrodes...
January 18, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29349543/saving-robots-improves-laparoscopic-performance-transfer-of-skills-from-a-serious-game-to-a-virtual-reality-simulator
#20
Wouter M IJgosse, Harry van Goor, Jan-Maarten Luursema
BACKGROUND: Residents find it hard to commit to structural laparoscopic skills training. Serious gaming has been proposed as a solution on the premise that it is effective and more motivating than traditional simulation. We establish construct validity for the laparoscopic serious game Underground by comparing laparoscopic simulator performance for a control group and an Underground training group. METHODS: A four-session laparoscopic basic skills course is part of the medical master students surgical internship at the Radboud University Medical Centre...
January 18, 2018: Surgical Endoscopy
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