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https://www.readbyqxmd.com/read/29792913/comparison-of-cerebral-ventricular-volumes-and-cortical-thicknesses-in-normal-rats-and-genetic-absence-epilepsy-gaers-a-developmental-study
#1
Özlem Kirazlı, Hüsniye Hacıoğlu Bay, Yusuf Özgür Çakmak, Filiz Onat, Safiye Çavdar
Ventricular enlargement and cortical atrophy have been associated with various central nervous system diseases. The aim of the present study was to measure the volumes of the lateral (LV) and third (3V) ventricles and to determine the cortical thickness for the motor (MCx), somatosensory (SSCx), visual (VCx) and auditory (AuCx) cortex and the striatum of Wistar rats, in a developmental series at 10, 20, 30, and 60 days postnatal, and to compare them with similar data from genetic absence epilepsy rats from Strasbourg (GAERS)...
May 21, 2018: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/29792570/a-model-for-predicting-the-risk-of-musculoskeletal-disorders-among-computer-professionals
#2
Vishnu Sasikumar, Second Champakkadayil Abdul Basheer Binoosh
OBJECTIVE: The objective of this study was to develop a model for predicting the risk of musculoskeletal disorders among computer professionals. MATERIALS AND METHODS: A preliminary study with a modified Nordic musculoskeletal questionnaire was conducted to identify the risk in different body parts of the professionals during their work. A discrete postural evaluation of the dynamic postures involved in the work was assessed using rapid upper limb assessment. The postural, physiological and work-related factors were considered as the attributes of the model...
May 24, 2018: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/29789667/imputation-of-missing-values-in-a-large-job-exposure-matrix-using-hierarchical-information
#3
Benjamin Roberts, Wenting Cheng, Bhramar Mukherjee, Richard L Neitzel
Job exposure matrices (JEMs) represent a useful and efficient approach for estimating occupational exposures. This study uses a large dataset of full-shift measurements and employs imputation strategies to develop noise exposure estimates for almost all broad level standard occupational classification (SOC) groups in the US. The JEM was constructed using 753,702 measurements from the government, private industry, and the published literature. Parametric Bayes imputation was used to take advantage of the hierarchical structure of the SOCs and the mean occupational noise exposures were estimated for all broad level SOCs, except those in major group 23-0000, for which no data were available...
May 23, 2018: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/29788084/microbial-activity-during-a-coastal-phytoplankton-bloom-on-the-western-antarctic-peninsula-in-late-summer
#4
María E Alcamán-Arias, Laura Farías, Josefa Verdugo, Tomás Alarcón-Schumacher, Beatriz Díez
Phytoplankton biomass during the austral summer is influenced by freezing and melting cycles as well as oceanographic processes that enable nutrient redistribution in the West Antarctic Peninsula (WAP). Microbial functional capabilities, metagenomic and metatranscriptomic activities as well as inorganic 13C- and 15N-assimilation rates were studied in the surface waters of Chile Bay during two contrasting summer periods in 2014. Concentrations of Chlorophyll a (Chla) varied from 0.3 mg m-3 in February to a maximum of 2...
May 1, 2018: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29787620/intact-goal-directed-control-in-treatment-seeking-drug-users-indexed-by-outcome-devaluation-and-pavlovian-to-instrumental-transfer-critique-of-habit-theory
#5
Lee Hogarth, Christa Lam-Cassettari, Helena Pacitti, Tara Currah, Justin Mahlberg, Lucie Hartley, Ahmed Moustafa
Animal studies have demonstrated that chronic exposure to drugs of abuse impairs goal-directed control over action selection indexed by the outcome-devaluation and specific Pavlovian to instrumental transfer procedures, suggesting this impairment might underpin addiction. However, there is currently only weak evidence for impaired goal-directed control in human drug users. Two experiments were undertaken in which treatment-seeking drug users and non-matched normative reference samples (controls) completed outcome-devaluation and specific Pavlovian to instrumental transfer procedures notionally translatable to animal procedures (Experiment 2 used a more challenging biconditional schedule)...
May 22, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29786412/the-use-of-scoring-balloons-in-the-superficial-femoral-artery
#6
Simon Bays
Percutaneous transluminal angioplasty and stenting is becoming increasingly the first line treatment for patients with both claudication and critical limb ischaemia instead of surgery, with the aim of returning the patient's quality of life in the former and preventing amputation. Drug eluting technologies have seen a large surge in popularity in recent years, and significant patient benefits have been seen with the use of drug eluting stents and balloons over the use of plain balloon angioplasty. Unfortunately in many patients with arterial disease there is significant vessel wall calcification - this can theoretically be a barrier to drug delivery, and can also be a contributing factor to flow limiting dissection and the subsequent need for bail out stenting...
May 22, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29784419/development-of-a-method-for-the-elemental-analysis-of-milk-powders-using-laser-ablation-inductively-coupled-plasma-mass-spectrometry-la-icp-ms-and-its-potential-use-in-geographic-sourcing
#7
Tricia Hoffman, Radojko Jaćimović, Lian Jie Bay, Julieta Griboff, Marta Jagodic, Magdalena Monferrán, Nives Ogrinc, Ivan Podkolzin, Daniel Wunderlin, Jose Almirall
Milk has been reported as one of the most adulterated foodstuffs in the developed and developing world. One way to detect adulteration is to determine whether the country of origin on the label could be the actual country of origin. Such profiling may be accomplished through the use of elemental analysis techniques, however this is a preliminary study and this goal is not yet met. In this study, a laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) method was developed for the analysis of solid milk powder and compared to k0 -instrumental neutron activation analysis (k0 -INAA) for a reference milk material (IAEA-153) as well as several milk samples from different countries...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29783123/sequentially-distant-but-structurally-similar-proteins-exhibit-fold-specific-patterns-based-on-their-biophysical-properties
#8
Senthilnathan Rajendran, Arunachalam Jothi
The Three-dimensional structure of a protein depends on the interaction between their amino acid residues. These interactions are in turn influenced by various biophysical properties of the amino acids. There are several examples of proteins that share the same fold but are very dissimilar at the sequence level. For proteins to share a common fold some crucial interactions should be maintained despite insignificant sequence similarity. Since the interactions are because of the biophysical properties of the amino acids, we should be able to detect descriptive patterns for folds at such a property level...
May 16, 2018: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/29782816/a-new-microsporidium-apotaspora-heleios-n-g-n-sp-from-the-riverine-grass-shrimp-palaemonetes-paludosus-decapoda-caridea-palaemonidae
#9
Yuliya Y Sokolova, Robin M Overstreet
We report a new microsporidium from a key species of the estuarine communities of the Gulf States, the Riverine grass shrimp, Palaemonetes paludosus. A milky-white shrimp was found in the Mobile Bay Delta, a large, oligohaline-freshwater wetland in Alabama, USA. Light microscopy of smears and thick sections of the abdominal tissues demonstrated infection with microsporidian spores enclosed in sporophorous vesicles (SVs) in sets of eight. Broadly oval spores measured 2.9 ± 0.06 x 1.7 ± 0.03 µm (2.5-3.3 x 1...
May 18, 2018: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/29781798/zhouia-spongiae-sp-nov-isolated-from-a-marine-sponge
#10
Lingping Zhuang, Binbin Lin, Fei Qin, Lianzhong Luo
A taxonomic study was carried out on strain HN-Y44T , which was isolated from sponge collected from Yangpu Bay, Hainan, China. Cells of strain HN-Y44T were Gram-stain-negative, non-motile, rod-shaped, yellow-pigmented and grew at 10-40 °C (optimum, 28 °C), at pH 6-10 (optimum, 7-8) and in 0-8 % (w/v) NaCl (optimum, 2-5 %). This isolate was positive for nitrate reduction, denitrification, oxidase, catalase and aesculin hydrolysis, but negative for indole production and urease. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain HN-Y44T belongs to the genus Zhouia and is clearly distinct from the other described species of this genus, Zhouia amylolytica, with a 16S rRNA gene sequence similarity of 96...
May 21, 2018: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29781680/provision-of-antiretroviral-therapy-for-children-in-nelson-mandela-bay-health-care-professionals-challenges
#11
Margaret Williams, Dalena R M Van Rooyen, Esmeralda J Ricks
BACKGROUND:  The human immunodeficiency virus and/or acquired immune deficiency syndrome (HIV/AIDS) pandemic continues to increase in prevalence worldwide, particularly in South Africa, and includes the often overlooked paediatric population. The provision of paediatric antiretroviral treatment (ART) is as essential for children as for adults, and has numerous obstacles, not least of which is lack of decentralisation of facilities to provide essential treatment. Optimising ART, care and support for HIV-positive children, and their caregivers, at public sector primary health care (PHC) clinics is crucial to improve morbidity and mortality rates in children...
March 12, 2018: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/29781638/a-model-based-test-for-treatment-effects-with-probabilistic-classifications
#12
Daniel R Cavagnaro, Clintin P Davis-Stober
Within modern psychology, computational and statistical models play an important role in describing a wide variety of human behavior. Model selection analyses are typically used to classify individuals according to the model(s) that best describe their behavior. These classifications are inherently probabilistic, which presents challenges for performing group-level analyses, such as quantifying the effect of an experimental manipulation. We answer this challenge by presenting a method for quantifying treatment effects in terms of distributional changes in model-based (i...
May 21, 2018: Psychological Methods
https://www.readbyqxmd.com/read/29780367/expression-of-mir-34a-in-t-cells-infected-by-human-t-lymphotropic-virus-1
#13
Varun K Sharma, Vittoria Raimondi, Katia Ruggero, Cynthia A Pise-Masison, Ilaria Cavallari, Micol Silic-Benussi, Vincenzo Ciminale, Donna M D'Agostino
Human T-lymphotropic virus 1 (HTLV-1) immortalizes T-cells and is the causative agent of adult T-cell leukemia/lymphoma (ATLL). HTLV-1 replication and transformation are governed by multiple interactions between viral regulatory proteins and host cell factors that remain to be fully elucidated. The present study investigated the impact of HTLV-1 infection on the expression of miR-34a, a microRNA whose expression is downregulated in many types of cancer. Results of RT-PCR assays showed that five out of six HTLV-1-positive cell lines expressed higher levels of miR-34a compared to normal PBMC or purified CD4+ T-cells...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29780299/the-first-loranthaceae-fossils-from-africa
#14
Friðgeir Grímsson, Alexandros Xafis, Frank H Neumann, Louis Scott, Marion K Bamford, Reinhard Zetter
An ongoing re-investigation of the early Miocene Saldanha Bay (South Africa) palynoflora, using combined light and scanning electron microscopy (single grain method), is revealing several pollen types new to the African fossil record. One of the elements identified is Loranthaceae pollen. These grains represent the first and only fossil record of Loranthaceae in Africa. The fossil pollen grains resemble those produced by the core Lorantheae and are comparable to recent Asian as well as some African taxa/lineages...
2018: Grana
https://www.readbyqxmd.com/read/29779673/how-food-rules-at-home-influence-independent-adolescent-food-choices
#15
Jennifer Wang, Priya Fielding-Singh
PURPOSE: The prevalence of unhealthy dietary behaviors among adolescents is high. We examined the effect of having health-oriented food rules at home on the healthiness of adolescents' independent food choices, and the necessity of parental oversight for such rules to be effective. METHODS: We surveyed a socioeconomically and racially diverse San Francisco Bay Area public high school in May 2017 (N = 1,246). We used ordinal logistic regressions to assess the relationships between adolescent-reported presence of health-oriented food rules at home and the healthiness of snacks selected by adolescents in a raffle, which included a randomized controlled experiment to manipulate the level of parental approval students needed to pick up their snacks...
May 15, 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29779309/-the-survival-prediction-model-of-advanced-gallbladder-cancer-based-on-bayesian-network-a-multi-institutional-study
#16
Z H Tang, Z M Geng, C Chen, S B Si, Z Q Cai, T Q Song, P Gong, L Jiang, Y H Qiu, Y He, W L Zhai, S P Li, Y C Zhang, Y Yang
Objective: To investigate the clinical value of Bayesian network in predicting survival of patients with advanced gallbladder cancer(GBC)who underwent curative intent surgery. Methods: The clinical data of patients with advanced GBC who underwent curative intent surgery in 9 institutions from January 2010 to December 2015 were analyzed retrospectively.A median survival time model based on a tree augmented naïve Bayes algorithm was established by Bayesia Lab software.The survival time, number of metastatic lymph nodes(NMLN), T stage, pathological grade, margin, jaundice, liver invasion, age, sex and tumor morphology were included in this model...
May 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29778968/environmental-risk-factors-associated-with-low-birth-weight-the-case-study-of-the-haifa-bay-area-in-israel
#17
Alina Svechkina, Jonathan Dubnov, Boris A Portnov
BACKGROUND: Low birth weight (LBW) is known to be associated with infant mortality and postnatal health complications. Previous studies revealed strong relationships between LBW rate and several socio-demographic factors, including ethnicity, maternal age, and family income. However, studies of association between LBW rate and environmental risk factors remain infrequent. STUDY METHODS: We retrieved a geo-referenced data set, containing 7216 individual records of children born in 2015 in the Haifa Bay Area in Israel...
May 17, 2018: Environmental Research
https://www.readbyqxmd.com/read/29777617/simulation-in-urology-to-train-non-technical-skills-in-ward-rounds
#18
K Somasundram, H Spence, A J Colquhoun, C Mcilhenny, C S Biyani, S Jain
OBJECTIVE: We have designed an exercise to train newly appointed Urology trainees in non-technical skills on ward rounds as a part of a simulation 'boot camp'. This paper reports our experience, including a qualitative analysis of participant feedback on the utility of this method of training. PATIENTS AND METHODS: The simulations took place in a high-fidelity simulated ward bay. Forty-eight doctors with formal Urology training ranging between 2-60 months (mean 19...
May 19, 2018: BJU International
https://www.readbyqxmd.com/read/29776593/heat-shock-influences-the-fatty-acid-composition-of-the-muscle-of-the-antarctic-fish-trematomus-bernacchii
#19
C Truzzi, S Illuminati, M Antonucci, G Scarponi, A Annibaldi
In the Ross Sea region (average temperature of -1.87 °C), shelf water warming up to +0.8-+1.4 °C is predicted by 2200, so there is an urgent need to understand how organisms can respond to rising temperatures. In this study, we analyzed the effect of a heat shock on the fatty acid (FAs) composition of muscle of the Antarctic teleost Trematomus bernacchii, caught in Terra Nova Bay (Ross Sea), and held in fish tanks at 0, +1 or +2 °C, for 1, 5 and 10 days. In general, heat shock produced, beyond a reduction in total lipid content correlated to the temperature, an increase in the percentage of saturated FAs, and a decrease in mono-unsaturated FAs; however, the level of poly-unsaturated FAs did not seem to directly correlate with temperature...
April 3, 2018: Marine Environmental Research
https://www.readbyqxmd.com/read/29776410/use-of-a-counsellor-supported-disclosure-model-to-improve-the-uptake-of-couple-hiv-testing-and-counselling-in-kenya-a-quasi-experimental-study
#20
Margaret Kababu, Eric Sakwa, Robinson Karuga, Annrita Ikahu, Inviolata Njeri, Jordan Kyongo, Catherine Khamali, Wanjiru Mukoma
BACKGROUND: Heterosexual couples account for 44% of new HIV infections in Kenya and there's low awareness of self and partner HIV status. Different strategies have been employed to promote couple HIV testing and counselling (CHTC). Despite this, HIV incidence among couples continues to rise. This study sought to assess the use of a counsellor-supported disclosure (CSD) model in enhancing the uptake of CHTC and the factors that were associated with it. METHODS: A pre-post quasi experimental study design with an intervention and a comparison arm was utilized...
May 18, 2018: BMC Public Health
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