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https://www.readbyqxmd.com/read/28813873/automation-of-motor-dexterity-assessment
#1
Patrick Heyer, Luis R Castrejon, Felipe Orihuela-Espina, Luis Enrique Sucar
Motor dexterity assessment is regularly performed in rehabilitation wards to establish patient status and automatization for such routinary task is sought. A system for automatizing the assessment of motor dexterity based on the Fugl-Meyer scale and with loose restrictions on sensing technologies is presented. The system consists of two main elements: 1) A data representation that abstracts the low level information obtained from a variety of sensors, into a highly separable low dimensionality encoding employing t-distributed Stochastic Neighbourhood Embedding, and, 2) central to this communication, a multi-label classifier that boosts classification rates by exploiting the fact that the classes corresponding to the individual exercises are naturally organized as a network...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811874/functional-roles-of-an-engineer-species-for-coastal-benthic-invertebrates-and-demersal-fish
#2
Aurélie Chaalali, Anik Brind'Amour, Stanislas F Dubois, Hervé Le Bris
Through their tissues or activities, engineer species create, modify, or maintain habitats and alter the distribution and abundance of many plants and animals. This study investigates key ecological functions performed by an engineer species that colonizes coastal ecosystems. The gregarious tubiculous amphipod Haploops nirae is used as a biological model. According to previous studies, the habitat engineered by H. nirae (i.e., Haploops habitat) could provide food and natural shelter for several benthic species such as benthic diatoms belonging to the gender Navicula, the micrograzer Geitodoris planata, or the bivalve Polititapes virgineus...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28811820/modified-mahalanobis-taguchi-system-for-imbalance-data-classification
#3
Mahmoud El-Banna
The Mahalanobis Taguchi System (MTS) is considered one of the most promising binary classification algorithms to handle imbalance data. Unfortunately, MTS lacks a method for determining an efficient threshold for the binary classification. In this paper, a nonlinear optimization model is formulated based on minimizing the distance between MTS Receiver Operating Characteristics (ROC) curve and the theoretical optimal point named Modified Mahalanobis Taguchi System (MMTS). To validate the MMTS classification efficacy, it has been benchmarked with Support Vector Machines (SVMs), Naive Bayes (NB), Probabilistic Mahalanobis Taguchi Systems (PTM), Synthetic Minority Oversampling Technique (SMOTE), Adaptive Conformal Transformation (ACT), Kernel Boundary Alignment (KBA), Hidden Naive Bayes (HNB), and other improved Naive Bayes algorithms...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28811517/heritability-of-the-symbiodinium-community-in-vertically-and-horizontally-transmitting-broadcast-spawning-corals
#4
Kate M Quigley, Bette L Willis, Line K Bay
The dinoflagellate-coral partnership influences the coral holobiont's tolerance to thermal stress and bleaching. However, the comparative roles of host genetic versus environmental factors in determining the composition of this symbiosis are largely unknown. Here we quantify the heritability of the initial Symbiodinium communities for two broadcast-spawning corals with different symbiont transmission modes: Acropora tenuis has environmental acquisition, whereas Montipora digitata has maternal transmission. Using high throughput sequencing of the ITS-2 region to characterize communities in parents, juveniles and eggs, we describe previously undocumented Symbiodinium diversity and dynamics in both corals...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28810531/mir-146a-overexpression-effectively-improves-experimental-allergic-conjunctivitis-through-regulating-cd4-cd25-t-cells
#5
Yang Yang, Xiaolong Yin, Jinglin Yi, Xiaowei Peng
OBJECTIVE: To study the mechanism of miR-146a in the regulation of allergic conjunctivitis (AC) through CD4(+)CD25(-)T cells. METHODS: BALB/c mice were sensitized with ragweed pollen (RW) and alum, and then challenged with RW. Eosinophil infiltration was determined using Giemsa assay. ELISA assay was performed to examine the level of antigen-specific IgE in the serum and cytokine levels in splenocytes. The expression of miR-146a was measured by qRT-PCR. Flow cytometric analysis was used to analyze the percentage of CD4(+)CD25(-)T cells and Tregs...
August 11, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28809144/defluviimonas-nitratireducens-sp-nov-isolated-from-surface-seawater
#6
Yang Liu, Qiliang Lai, Wanpeng Wang, Zongze Shao
A bacterial strain, designated DL5-4T, was isolated from the surface seawater of Dalian Bay and characterized using a polyphasic taxonomy approach. Cells of DL5-4T were Gram-staining-negative, non-motile and short-rod-shaped. Growth was observed at 8-40 °C (optimum 28-30 °C), at pH 6-9 (optimum pH 7) and in 0-7 % NaCl (optimum 1-3 %, w/v). The results of phylogenetic analysis based on 16S rRNA gene sequences indicated that DL5-4T formed an independent branch with members of the genus Defluviimonas, sharing high similarities with five related type strains, Defluviimonas aquaemixtae CDM-7T (96...
August 15, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28808879/influence-of-ignited-sediments-on-external-phosphorus-adsorption-and-sedimentary-phosphorus-forms
#7
PeiYing Zhu, DaPeng Li, Yong Huang, Yong Li
Phosphorus (P) adsorpted by sediments, when covered by and mixed with ignited sediments from Meiliang Bay in Tai Lake, was analyzed in the laboratory. Potassium dihydrogen phosphate (KH2PO4) was added to the parallel experimental units to simulate periodic external P input. Based on the Langmuir model, the sediments after ignition had a greater Smax (maximum P adsorption), a lower equilibrium phosphorus concentration at zero adsorption (EPC0), and a lower degree of phosphorus saturation in comparison with sediments without ignition...
August 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28808842/colonic-motor-dysfunctions-in-a-mouse-model-of-high-fat-diet-induced-obesity-an-involvement-of-a2b-adenosine-receptors
#8
Luca Antonioli, Carolina Pellegrini, Matteo Fornai, Erika Tirotta, Daniela Gentile, Laura Benvenuti, Maria Cecilia Giron, Valentina Caputi, Ilaria Marsilio, Genny Orso, Nunzia Bernardini, Cristina Segnani, Chiara Ippolito, Balázs Csóka, Zoltán H Németh, György Haskó, Carmelo Scarpignato, Corrado Blandizzi, Rocchina Colucci
Adenosine A2B receptors (A2BR) regulate several enteric functions. However, their implication in the pathophysiology of intestinal dysmotility associated with high-fat diet (HFD)-induced obesity has not been elucidated. We investigated the expression of A2BR in mouse colon and their role in the mechanisms underlying the development of enteric dysmotility associated with obesity. Wild-type C57BL/6J mice were fed with HFD (60% kcal from fat) or normocaloric diet (NCD; 18% kcal from fat) for 8 weeks. Colonic A2BR localization was examined by immunofluorescence...
August 14, 2017: Purinergic Signalling
https://www.readbyqxmd.com/read/28808688/adaptive-mistranslation-accelerates-the-evolution-of-fluconazole-resistance-and-induces-major-genomic-and-gene-expression-alterations-in-candida-albicans
#9
Tobias Weil, Rodrigo Santamaría, Wanseon Lee, Johan Rung, Noemi Tocci, Darren Abbey, Ana R Bezerra, Laura Carreto, Gabriela R Moura, Mónica Bayés, Ivo G Gut, Attila Csikasz-Nagy, Duccio Cavalieri, Judith Berman, Manuel A S Santos
Regulated erroneous protein translation (adaptive mistranslation) increases proteome diversity and produces advantageous phenotypic variability in the human pathogen Candida albicans. It also increases fitness in the presence of fluconazole, but the underlying molecular mechanism is not understood. To address this question, we evolved hypermistranslating and wild-type strains in the absence and presence of fluconazole and compared their fluconazole tolerance and resistance trajectories during evolution. The data show that mistranslation increases tolerance and accelerates the acquisition of resistance to fluconazole...
July 2017: MSphere
https://www.readbyqxmd.com/read/28808149/acute-coronary-syndrome-what-is-the-affected-artery-where-is-the-occlusion-located-and-how-important-is-the-myocardial-mass-involved
#10
Miguel Fiol-Sala, Antonio Bayés de Luna
No abstract text is available yet for this article.
August 15, 2017: Circulation
https://www.readbyqxmd.com/read/28807722/coronary-microvascular-dysfunction-is-not-associated-with-a-history-of-reproductive-risk-factors-in-women-with-angina-pectoris-an-ipower-substudy
#11
Hannah Elena Suhrs, Anna Meta Kristensen, Anna Bay Rask, Marie Mide Michelsen, Daria Frestad, Naja Dam Mygind, Kira Bové, Eva Prescott
BACKGROUND: Reproductive risk factors such as preeclampsia and recurrent miscarriages have been associated with adverse cardiovascular (CV) events. Underlying coronary microvascular dysfunction (CMD) may be a common denominator. PURPOSE: We investigated whether a history of reproductive risk factors was associated with CMD in women with angina pectoris and no obstructive coronary artery disease (CAD). METHODS: Participants from the iPOWER study, including women with angina pectoris and no obstructive CAD (<50% stenosis), were invited to complete an electronic survey regarding reproductive risk factors: recurrent miscarriages, gestational diabetes, preeclampsia, rhesus immunity, polycystic ovary syndrome and menopausal status as well as migraine and Raynaud phenomenon...
August 11, 2017: Maturitas
https://www.readbyqxmd.com/read/28807715/chrodrimanins-o-s-from-the-fungus-penicillium-sp-scs-kfd09-isolated-from-a-marine-worm-sipunculusnudus
#12
Fan-Dong Kong, Ren-Shuai Zhang, Qing-Yun Ma, Qing-Yi Xie, Pei Wang, Peng-Wei Chen, Li-Man Zhou, Hao-Fu Dai, Du-Qiang Luo, You-Xing Zhao
Five new meroterpenoids, chrodrimanins O-S (1-5), as well as a known one (6), were isolated from the fermentation broth of Penicillium sp. SCS-KFD09 isolated from a marine worm, Sipunculusnudus, from Haikou Bay, China. The structures including the absolute configurations of the new compounds were unambiguously elucidated by spectroscopic data and ECD spectra analysis along with quantum ECD calculations. Among them, compound 1 represents the first example of an unusual trichlorinated meroterpenoid with an unique dichlorine functionality...
August 11, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28807668/evidence-that-blood-flukes-trematoda-aporocotylidae-of-chondrichthyans-infect-bivalves-as-intermediate-hosts-indications-of-an-ancient-diversification-of-the-schistosomatoidea
#13
Thomas H Cribb, Rowan C Chick, Wayne O'Connor, Stephan O'Connor, Daniel Johnson, Kim B Sewell, Scott C Cutmore
Blood flukes (Aporocotylidae) of actinopterygians (bony fishes), have been shown to infect freshwater gastropods and marine polychaetes as intermediate hosts. However, no life cycle is known for any aporocotylid of chondrichthyans (cartilaginous fishes) and no adult aporocotylid has been linked to a cercaria infecting a bivalve. Here we report two novel infections that fill these gaps. Cercariae consistent with the family Aporocotylidae were found developing in sporocysts in the gonad of the surf pipi, Donax deltoides Lamarck, 1818 (Bivalvia: Donacidae), from Stockton Beach, central New South Wales, Australia...
August 11, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28807410/macrofaunal-community-structure-in-bah%C3%A3-a-concepci%C3%A3-n-chile-before-and-after-the-8-8-mw-maule-mega-earthquake-and-tsunami
#14
Paula J Cárcamo, Eduardo Hernández-Miranda, Rodrigo Veas, Renato A Quiñones
Faunal assemblages of subtidal sedimentary environments are key components of coastal ecosystems. Benthic communities inhabiting the coastal zone near urban centers in Concepción Bay (Chile) have been described as highly disturbed (i.e. impoverished in diversity and species richness). This is due to the frequent presence of hypoxic conditions at the bottom due to the intrusion of low oxygen Equatorial Subsurface Water, high natural productivity and the high load of organic matter generated by several anthropogenic activities...
July 25, 2017: Marine Environmental Research
https://www.readbyqxmd.com/read/28806356/respiratory-viral-infections-and-coinfections-caused-by-human-metapneumovirus-in-children-with-cancer
#15
Sema Büyükkapu Bay, Rejin Kebudi, Selim Badur
No abstract text is available yet for this article.
September 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28805909/genomewide-association-study-for-production-and-meat-quality-traits-in-canchim-beef-cattle
#16
G G Santiago, F Siqueira, F F Cardoso, L C A Regitano, R Ventura, B P Sollero, M D Souza, F B Mokry, A B R Ferreira, R A A Torres
The commercial value of the bovine carcass is determined by a set of traits, such as weight, yield, back fat thickness, and marbling; therefore, the genetic improvement of growth, meat, and carcass quality traits is an important tool to add value to the supply chain. Genomewide association studies (GWAS) enable the identification of loci that control phenotypic expression of quantitative traits (QTL). Therefore, the objective of this work was to perform a GWAS to identify genomic regions and genes associated with growth, carcass traits, and meat quality in Canchim beef cattle...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28804980/using-bayes-factors-to-evaluate-evidence-for-no-effect-examples-from-the-sips-project
#17
Zoltan Dienes, Simon Coulton, Nick Heather
AIMS: To illustrate how Bayes Factors are important for determining the effectiveness of interventions. METHOD: We consider a case where inappropriate conclusions were publicly drawn based on significance testing, namely the SIPS Project (Screening and Intervention Programme for Sensible drinking), a pragmatic, cluster-randomized controlled trial in each of two healthcare settings and in the criminal justice system. We show how Bayes Factors can disambiguate the non-significant findings from the SIPS Project and thus determine whether the findings represent evidence of absence or absence of evidence...
August 13, 2017: Addiction
https://www.readbyqxmd.com/read/28804930/gaussian-covariance-graph-models-accounting-for-correlated-marker-effects-in-genome-wide-prediction
#18
C A Martínez, K Khare, S Rahman, M A Elzo
Several statistical models used in genome-wide prediction assume uncorrelated marker allele substitution effects, but it is known that these effects may be correlated. In statistics, graphical models have been identified as a useful tool for covariance estimation in high-dimensional problems and it is an area that has recently experienced a great expansion. In Gaussian covariance graph models (GCovGM), the joint distribution of a set of random variables is assumed to be Gaussian and the pattern of zeros of the covariance matrix is encoded in terms of an undirected graph G...
August 13, 2017: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/28804568/preventive-effects-of-kudzu-root-on-bone-loss-and-cartilage-degradation-in-ovariectomized-rat
#19
Yunyun Luo, Shuang Zheng, Yujia Ding, Yueqin Dai, Yi Zhou, Ruifeng Xiang, Anne C Bay-Jensen, Morten A Karsdal, Per Qvist, Qinlong Zheng
The clinical utility of Traditional Chinese Medicine (TCM) herbs/roots extracts in osteoporosis (OP) and osteoarthritis (OA) has been described in multiple reports, but there have been few studies of TCM for preventing bone loss and cartilage degradation simultaneously. Six-month-old female Sprague-Dawley rats each were subjected to ovariectomized (OVX) or sham surgery and treated orally once daily with herbal extracts or vehicle. Body weight was recorded weekly, and blood samples were collected from fasting animals at different time points...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28803870/industrial-melanism-in-the-seasnake-emydocephalus-annulatus
#20
Claire Goiran, Paco Bustamante, Richard Shine
Although classically associated with urban environments in invertebrates, melanism in terrestrial snakes is more often linked to occupancy of cool climates [1-3]. Thermal advantages to melanism do not apply in aquatic snakes [4], but although turtle-headed seasnakes (Emydocephalus annulatus) are banded or blotched across a wide geographic range [5], most individuals are melanic in polluted inshore bays of the Pacific island of New Caledonia [4]. Why has melanism evolved in these urban sites? Because trace elements bind to melanin, darker feathers enhance a bird's ability to shed pollutants [6]...
August 8, 2017: Current Biology: CB
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