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https://www.readbyqxmd.com/read/28931142/malaria-prevention-strategies-and-recommendations-from-chemoprophylaxis-to-stand-by-emergency-treatment-a-10-year-prospective-study-in-a-swiss-travel-clinic
#1
Rim Boubaker, Annie Hérard Fossati, Pierrette Meige, Catherine Mialet, Chantal Ngarambe Buffat, Jacynthe Rochat, Manisinh Souvannaraj-Blanchant, Mediatrice Uwanyiligira, Francine Widmer, Sylvie Payot, Laurence Rochat, Serge de Vallière, Valérie D'Acremont, Blaise Genton
Background: There are several possible malaria prevention strategies for travellers. In Switzerland, chemoprophylaxis (CP) is recommended for persons visiting areas highly endemic for malaria and stand-by emergency treatment (SBET) for areas with moderate to low risk. Objective: To describe the type of malaria prevention prescribed to travel clinic attendees with a specific focus on changes over time following adaptation of recommendations. Methods: All pre-travel first consultation data recorded between November 2002 and December 2012 were included...
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28930963/role-of-autophagy-and-its-molecular-mechanisms-in-mice-intestinal-tract-after-severe-burn
#2
Duan Y Zhang, Wei Qiu, PeiS Jin, Peng Wang, Yong Sun
BACKGROUND: Severe burn can lead to hypoxia/ischemia of intestinal mucosa. Autophagy is the process of intracellular degradation, which is essential for cell survival under stresses, such as hypoxia/ischemia and nutrient deprivation. The present study was designed to investigate whether there were changes in intestinal autophagy after severe burn in mice and further to explore the effect and molecular mechanisms of autophagy on intestinal injury. METHODS: This study includes three experiments...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930875/the-kinetic-determinants-of-reactive-strength-in-highly-trained-sprint-athletes
#3
Jamie Douglas, Simon Pearson, Angus Ross, Mike McGuigan
The purpose of this study was to determine the braking and propulsive phase kinetic variables underpinning reactive strength in highly trained sprint athletes in comparison to a non-sprint trained control group. Twelve highly trained sprint athletes and twelve non-sprint trained participants performed drop jumps (DJs) from 0.25m, 0.50m and 0.75m onto a force plate. One familiarization session was followed by an experimental testing session within the same week. Reactive strength index (RSI), contact time, flight time, and leg stiffness were determined...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28930430/novel-strategies-for-the-production-of-fuels-lubricants-and-chemicals-from-biomass
#4
Sankaranarayanapillai Shylesh, Amit A Gokhale, Christopher R Ho, Alexis T Bell
Growing concern with the environmental impact of CO2 emissions produced by combustion of fuels derived from fossil-based carbon resources has stimulated the search for renewable sources of carbon. Much of this focus has been on the development of methods for producing transportation fuels, the major source of CO2 emissions today, and to a lesser extent on the production of lubricants and chemicals. First-generation biofuels such as bioethanol, produced by the fermentation of sugar cane- or corn-based sugars, and biodiesel, produced by the transesterification reaction of triglycerides with alcohols to form a mixture of long-chain fatty esters, can be blended with traditional fuels in limited amounts and also arise in food versus fuel debates...
September 20, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28929990/microbial-composition-affects-the-performance-of-an-artificial-tephritid-larval-diet
#5
P Rempoulakis, S Sela Saldinger, E Nemny-Lavy, R Pinto, A Birke, D Nestel
The present study investigated the patterns of microorganisms in an artificial larval diet during Dacus ciliatus (Diptera; Tephritidae) larval development. Microbial population contents in the diet of total heterotrophic bacteria, yeast and molds, coliform and lactobacilli, and their dynamics during development, were monitored. Initially, the microbial composition in diet trays failing to produce viable pupae and in trays successfully producing pupae and adult flies was characterized. The failing diet trays contained large populations of lactobacilli that increased during larval development, and low populations of coliforms...
September 20, 2017: Bulletin of Entomological Research
https://www.readbyqxmd.com/read/28929927/ankle-taping-can-reduce-external-ankle-joint-moments-during-drop-landings-on-a-tilted-surface
#6
Nahoko Sato, Hiroyuki Nunome, Luke S Hopper, Yasuo Ikegami
Ankle taping is commonly used to prevent ankle sprains. However, kinematic assessments investigating the biomechanical effects of ankle taping have provided inconclusive results. This study aimed to determine the effect of ankle taping on the external ankle joint moments during a drop landing on a tilted surface at 25°. Twenty-five participants performed landings on a tilted force platform that caused ankle inversion with and without ankle taping. Landing kinematics were captured using a motion capture system...
September 20, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28929873/assessing-the-prospects-for-physician-supply-and-demand-in-canada-wishing-it-was-rocket-science
#7
Owen Adams, Tara S Chauhan, Lynda Buske
"It's not rocket science" is an often used phrase to describe tasks that are not very difficult. Although rocketry has proven to be an exacting science with highly predictable results, the same cannot be said for physician workforce planning in Canada. The "boom" in physician supply in the 1960s and 1970s was followed by a "bust" in the early 1990s and a further boom in the 2000s. A large generational shift in the physician population is anticipated between now and 2030; the proportion of "boomers" (1946-1964) will drop from 43% to 16% of the practising profession...
July 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28929797/automated-early-detection-of-drops-in-commercial-egg-production-using-neural-networks
#8
I Ramírez-Morales, E Fernández-Blanco, D Rivero, A Pazos
1. The purpose of this work was to support decision making in poultry farms by performing automatic early detection of anomalies in egg production. 2. Unprocessed data were collected from a commercial egg farm on a daily basis over 7 years. Records from a total of 24 flocks, each with approximately 20 000 laying hens, were studied. 3. Other similar works have required a prior feature extraction by a poultry expert, and this method is dependent on time and expert knowledge. 4. The present approach reduces the dependency on time and expert knowledge because of the automatic selection of relevant features and the use of artificial neural networks capable of cost-sensitive learning...
September 20, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28929736/substrate-versatile-approach-to-robust-antireflective-and-superhydrophobic-coatings-with-excellent-self-cleaning-property-in-varied-environments
#9
Tingting Ren, Junhui He
Robust antireflective and superhydrophobic coatings are highly desired in wide applications, such as optical devices, solar cell panels, architectural and automotive glasses, lab-on chip systems, and windows for electronic devices. Meanwhile, simple, low-cost, and substrate-versatile fabrication is also essential toward real applications of such coatings. Herein, we developed a substrate-versatile strategy to fabricate robust antireflective and superhydrophobic coatings with excellent self-cleaning property in varied environments, including air and oil and after oil contamination...
September 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28929562/seroepidemiological-trend-of-strongyloidiasis-in-the-bolivian-chaco-1987-2013-in-the-absence-of-disease-specific-control-measures
#10
Michele Spinicci, Fabio Macchioni, Antonia Mantella, Simona Gabrielli, Mimmo Roselli, David Rojo Mayaregua, Joaquín Monasterio Pinckert, Herlan Gamboa Barahona, Grover Adolfo Paredes, Percy Halkyer, Gabriella Cancrini, Piero Olliaro, Antonio Montresor, Alessandro Bartoloni
OBJECTIVES: The prevalence of Strongyloides stercoralis infections is grossly underestimated because infections go mostly undetected, though they can persist for a lifetime due to the auto-infective cycle. In the Bolivian Chaco, the prevalence of soil-transmitted nematodes dropped dramatically in the past 25 years, but the mebendazole used for preventive chemotherapy has no effect on S. stercoralis. Meanwhile, the prevalence of intestinal protozoan infections remains unchanged. We compared S...
September 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28929253/positive-rheotaxis-extended-drop-a-one-step-procedure-to-select-and-recover-sperm-with-mature-chromatin-for-intracytoplasmic-sperm-injection
#11
Hamilton De Martin, Marcello S Cocuzza, Bruno C Tiseo, Guilherme J A Wood, Eduardo P Miranda, Pedro A A Monteleone, José Maria Soares, Paulo C Serafini, Miguel Srougi, Edmund C Baracat
PURPOSE: The purpose of this study was to develop a novel one-step ICSI approach to select sperm with better chromatin maturity than the conventional method. METHODS: This was a pilot diagnostic study, which prospectively recruited men during a 6-month period in a University-affiliated infertility centre. Forty consecutive semen samples were provided for analysis. The positive rheotaxis extended drop (PRED) was set up creating a pressure and viscosity gradient. Each semen sample was divided into four aliquots: one aliquot for density gradient centrifugation (DGC), two aliquots for PRED (fresh semen (PRED-FS) and processed semen (PRED-DGC)), and one aliquot as the control (FS)...
September 19, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28929246/a-numerical-study-of-the-hemodynamic-effect-of-the-aortic-valve-on-coronary-flow
#12
Shaily Wald, Alex Liberzon, Idit Avrahami
During diastole, coronary perfusion depends on the pressure drop between the myocardial tissue and the coronary origin located at the aortic root. This pressure difference is influenced by the flow field near the closing valve leaflets. Clinical evidence is conclusive that patients with severe aortic stenosis (AS) suffer from diastolic dysfunction during hyperemia, but show increased coronary blood flow (CBF) during rest. Transcatheter aortic valve implantation (TAVI) was shown to decrease rest CBF along with its main purpose of improving the aortic flow and reducing the risk of heart failure...
September 19, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28929170/comparison-of-two-6-minute-walk-tests-to-assess-walking-capacity-in-polio-survivors
#13
Merel-Anne Brehm, Suzan Verduijn, Jurgen Bon, Nicoline Bredt, Frans Nollet
OBJECTIVE: To compare walking dynamics and test-retest reliability for 2 frequently applied walk tests in polio survivors: the 6-minute walk test (6MWT) to walk as far as possible; and the 6-minute walking energy cost test (WECT) at comfortable speed. DESIGN: Observational study. PARTICIPANTS: Thirty-three polio survivors, able to walk ≥ 150 m. METHODS: On the same day participants performed a 6MWT and a WECT, which were repeated 1-3 weeks later...
September 20, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28928582/repetitive-transcranial-magnetic-stimulation-in-chronic-pain-a-meta-analysis
#14
Basavana Goudra, Dipal Shah, Ganesh Balu, Gowri Gouda, Alan Balu, Anuradha Borle, Preet Mohinder Singh
BACKGROUND: In this meta-analysis, we explore the role of repetitive transcranial magnetic stimulation (rTMS), a noninvasive neuromodulation technique in the treatment of chronic pain. METHODS: Studies comparing rTMS and conventional treatment for chronic pain were searched. The comparison was made for decrease in the pain scores with and without (sham) the use of rTMS after a follow-up interval of 4-8 weeks. All reported pain scores were converted into a common scale ranging from "0" (no pain) to "10" (worst pain)...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28928498/innovative-application-of-cox-flexion-distraction-decompression-to-the-knee-a-retrospective-case-series
#15
Luigi Albano
OBJECTIVE: The purpose of this study is to introduce the application of Cox flexion distraction decompression as an innovative approach to treating knee pain and osteoarthritis. METHODS: Six months of clinical files from one chiropractic practice were retrospectively screened for patients who had been treated for knee pain. Twenty-five patients met the criteria for inclusion. The treatment provided was Cox flexion distraction decompression. Pre-treatment and post-treatment visual analog pain scales (VAS) were used to measure the results...
August 2017: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/28928447/the-roles-of-wettability-and-surface-tension-in-droplet-formation-during-inkjet-printing
#16
Bing He, Sucui Yang, Zhangrong Qin, Binghai Wen, Chaoying Zhang
This paper describes a lattice Boltzmann-based binary fluid model for inkjet printing. In this model, a time-dependent driving force is applied to actuate the droplet ejection. As a result, the actuation can be accurately controlled by adjusting the intensity and duration of the positive and negative forces, as well as the idle time. The present model was verified by reproducing the actual single droplet ejection process captured by fast imaging. This model was subsequently used to investigate droplet formation in piezoelectric inkjet printing...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28928044/electrocardiographic-biomarkers-to-confirm-drug-s-electrophysiological-effects-used-for-proarrhythmic-risk-prediction-under-cipa
#17
Jose Vicente, Meisam Hosseini, Lars Johannesen, David G Strauss
The ECG plays a critical role in the thorough QT study. This clinical study is part of the assessment of proarrhythmic potential of drugs under the current regulatory paradigm. While the current paradigm has been successful in preventing drugs with unexpected QT prolongation or torsade risk from reaching the market, the focus on QT prolongation has likely resulted in potentially beneficial compounds with minimal torsade risk being dropped from development. The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative is developing and validating a new mechanistic-based paradigm for cardiac safety evaluation of drugs...
August 9, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28927828/fatty-acid-oxidation-defects-presenting-as-primary-myopathy-and-prominent-dropped-head-syndrome
#18
Seena Vengalil, Veeramani Preethish-Kumar, Kiran Polavarapu, Rita Christopher, Narayanappa Gayathri, Archana Natarajan, Mahadevappa Manjunath, Saraswati Nashi, Chandrajit Prasad, Atchayaram Nalini
Fatty acid oxidation disorders presenting as primary myopathy is relatively rare and also diagnostically challenging. Its association with "dropped head syndrome" is reported till date in single cases of carnitine deficiency and multiple acyl CoA dehydrogenase deficiency (MADD).We studied nineteen cases of primary progressive myopathy confirmed to have fatty acid oxidation defects by Tandem Mass Spectrometry. The detailed clinical, muscle histopathology, tandem mass spectrometry and muscle magnetic resonance imaging (MRI) findings are presented here...
August 24, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28927562/periarticular-injection-of-tranexamic-acid-reduces-blood-loss-and-the-necessity-for-allogeneic-transfusion-after-total-knee-arthroplasty-using-autologous-transfusion-a-retrospective-observational-study
#19
Sain Yozawa, Hiroyasu Ogawa, Kazu Matsumoto, Haruhiko Akiyama
BACKGROUND: This study aimed to examine the influence of a periarticular injection of tranexamic acid (TXA) on blood loss after a total knee arthroplasty (TKA) in patients who received an autologous blood transfusion. METHODS: We retrospectively reviewed the medical charts of 82 patients (88 consecutive knees) who underwent a primary unilateral TKA with or without a periarticular TXA injection (TXA and control groups, respectively). All patients underwent an autologous blood transfusion...
August 24, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28927560/patient-variation-limits-use-of-fixed-references-for-femoral-rotation-component-alignment-in-total-knee-arthroplasty
#20
Joshua G Twiggs, David M Dickison, Elizabeth C Kolos, Caitlin E Wilcox, Justin P Roe, Brett A Fritsch, Stephen J McMahon, Brad P Miles, Andrew J Ruys
BACKGROUND: Optimal rotational alignment of the femoral component is a common goal during total knee arthroplasty. The posterior condylar axis (PCA) is thought to be the most reproducible reference in surgery, while the transepicondylar axis (TEA) seems to better approximate the native kinematic flexion axis. This study sought to determine if rules based on patient gender or coronal alignment could allow reliable reproduction of the TEA from the PCA. METHODS: Three-dimensional models based on preoperative computed tomography were made representing a patient's arthritic knee joint...
August 24, 2017: Journal of Arthroplasty
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