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Bladder Amyloidosis

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https://www.readbyqxmd.com/read/29173275/images-in-urology-localized-primary-amyloidosis-of-the-urinary-bladder
#1
Shawn Varghese, Nathan Colin Wong, Bobby Shayegan
No abstract text is available yet for this article.
December 1, 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28958583/external-beam-radiation-therapy-for-amyloidosis-of-the-urinary-bladder
#2
Christopher T Cooper, Bruce D Greene, Jeffrey E Fegan, Douglas Rovira, Morie A Gertz, David M Marcus
No abstract text is available yet for this article.
August 16, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28891012/visualization-of-multiple-organ-amyloid-involvement-in-systemic-amyloidosis-using-11-c-pib-pet-imaging
#3
Naoki Ezawa, Nagaaki Katoh, Kazuhiro Oguchi, Tsuneaki Yoshinaga, Masahide Yazaki, Yoshiki Sekijima
PURPOSE: To investigate the utility of Pittsburgh compound B (PiB) positron emission tomography (PET) imaging for evaluating whole-body amyloid involvement in patients with systemic amyloidosis. METHODS: Whole-body (11)C-PiB PET was performed in seven patients with systemic immunoglobulin light-chain (AL) amyloidosis, seven patients with hereditary transthyretin (ATTRm) amyloidosis, one asymptomatic TTR mutation carrier and three healthy controls. The correlations between clinical organ involvement, radiological (11)C-PiB uptake and histopathological findings were analysed for each organ...
September 10, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28832315/amyloidosis-and-acute-hemorrhage-of-the-kidney-ureter-and-bladder
#4
Dany N Hanna, Jason A Levy, Jonah S Marshall
Gross hematuria is a common occurrence in adults. The differential diagnosis is extensive, including: malignancy, trauma, inflammation of the urinary tract, and stones. While, urinary tract amyloidosis represents only a small percentage of causative gross hematuria, it is concerning because of its superficial resemblance to malignant processes. We report the case of an 82-year-old male with concurrent primary amyloidosis of the kidney, ureter and bladder in the setting of acute hemorrhage. Histopathological examination of several biopsied samples confirmed our diagnosis...
August 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28646945/primary-amyloidosis-of-the-bladder-a-mimicker-of-bladder-cancer
#5
Ryan Fitzpatrick, Nicholas R Paterson, Eric C Belanger, Arleigh McCurdy, James Watterson
Amyloidosis is a protein folding disorder characterized by the deposition of fibrillar proteins into solid organs or tissues. Primary localized amyloidosis of the bladder is very rare and can mimic bladder cancer in its presentation with hematuria, lower urinary tract symptoms or a mass on imaging. A case of localized amyloidosis of the bladder in a 48-year-old man with painless gross hematuria and evidence of bladder mass on ultrasound is presented. Amyloidosis is a rare but important non-malignant process of the bladder...
June 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28417073/primary-amyloidosis-of-the-urinary-bladder-a-case-report
#6
Liwen Zhao, Lu Jin, Jing Quan, Xiang Pan, Lijun Zhou, Jian Peng, Zebo Chen, Shangqi Yang, Xiangming Mao, Yongqing Lai
Primary amyloidosis of the urinary bladder is a rare disease, with only approximately 200 cases reported in the literature. We herein present a case of amyloidosis of the urinary bladder with painful gross hematuria. Pelvic Computed Tomography showed uneven thickening of the bladder wall suspicious of neoplastic lesion. Cystoscopy and transurethral resection were performed. Congo-red staining confirmed amyloidosis it was. Postoperative recovery was good and close follow-up was recommended after discharged. Amyloidosis is usually benign, while it can masquerade as a malignancy...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28079503/novel-evidences-of-atypical-manifestations-in-cryopyrin-associated-periodic-syndromes
#7
Segundo Bujan-Rivas, Maria Basagaña, Francisca Sena, Maria Méndez, Maria Teresa Dordal, Eva Gonzalez-Roca, Estibaliz Ruiz-Ortiz, Anna Mensa-Vilaró, Susana Plaza, Consuelo Modesto, Josep Ordi-Ros, Jordi Yagüe, Ferrán Martínez-Valle, Juan Ignacio Aróstegui
OBJECTIVES: Cryopyrin-associated periodic syndromes (CAPS) usually start during infancy as an urticarial-like rash and a marked acute phase response, with additional manifestations appearing during its evolution. The aim of this study was to expand the clinical diversity of CAPS by the description of novel atypical features. METHODS: Clinical data were collected from patients' medical charts. Sanger sequencing analyzed NLRP3. Response to anti-IL-1 blockade was evaluated by clinical assessments and by measurements of laboratory parameters...
January 9, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27957427/a-rare-case-of-hematuria-primary-amyloidosis-of-the-bladder-neck
#8
Sotonye Tolofari, Asif Ansari, Ross J Knight
Primary and localized amyloidosis of the urinary tract is considered to be a rare clinical entity with approximately 160 cases documented in the literature. Here we present a case of a 77 year old gentleman with painless visible hematuria. Flexible cystoscopy revealed abnormal and polypoidal bladder mucosa. Transurethral resection of these lesions revealed histology with congo-red staining and positive green-apple birefringence, these findings are consistent with amyloidosis. There has so far been no sign of recurrence in this gentleman, with routine cystoscopic surveillance...
January 2017: Urology Case Reports
https://www.readbyqxmd.com/read/27760547/secondary-bladder-amyloidosis-with-familial-mediterranean-fever-in-a-living-donor-kidney-transplant-recipient-a-case-report
#9
Sentaro Imamura, Shintaro Narita, Ryuta Nishikomori, Hiroshi Tsuruta, Kazuyuki Numakura, Atsushi Maeno, Mitsuru Saito, Takamitsu Inoue, Norihiko Tsuchiya, Hiroshi Nanjo, Toshio Heike, Shigeru Satoh, Tomonori Habuchi
BACKGROUND: Secondary bladder amyloidosis is an extremely rare disease, resulting from a chronic systematic inflammatory disorder associated with amyloid deposits. Although uncommon in Japan, familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease characterized by recurrent episodes of fever of short duration and serositis and is frequently associated with systemic amyloidosis. Here, we present a case of a Japanese patient complaining of fever and macroscopic hematuria after a living donor renal transplantation...
October 19, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/26900233/primary-amyloidosis-of-urinary-bladder-mimicking-transitional-cell-carcinoma-bladder
#10
S C Karan, Amit Kumar Shah, Anand Srivastava, Reena Bhardwaj
No abstract text is available yet for this article.
January 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/26688234/natural-history-and-outcomes-in-localised-immunoglobulin-light-chain-amyloidosis-a-long-term-observational-study
#11
Shameem Mahmood, Frank Bridoux, Christopher P Venner, Sajitha Sachchithanantham, Janet A Gilbertson, Dorota Rowczenio, Thomas Wagner, Rabya Sayed, Ketna Patel, Marianna Fontana, Carol J Whelan, Helen J Lachmann, Philip N Hawkins, Julian D Gillmore, Ashutosh D Wechalekar
BACKGROUND: Localised immunoglobulin light-chain amyloidosis, involving one type of tissue, is rare. Little systematic data exists regarding clinical presentations, course or outcomes, or risk of progression to systemic amyloidosis. We aimed to report clinical features and outcomes of a large series of patients with localised light-chain amyloidosis. METHODS: We examined data for all patients with localised amyloidosis who were diagnosed, assessed, and followed at the UK National Amyloidosis Centre (NAC) between Jan 2, 1980, and Dec 15, 2011, from the NAC database and written records...
June 2015: Lancet Haematology
https://www.readbyqxmd.com/read/25685452/urinary-schistosomiasis-review
#12
REVIEW
Rashad S Barsoum
UNLABELLED: In this review, the clinical manifestations of urinary schistosomiasis are displayed from a pathogenetic perspective. According to the prevailing host's immune response profile, urinary schistosomiasis may be broadly categorized into cell-mediated and immune-complex-mediated disorders. The former, usually due to Schistosoma haematobium infection, are attributed to the formation of granulomata along the entire urinary tract. As they heal with excessive fibrosis, they may lead to strictures, calcifications and urodynamic abnormalities...
September 2013: Journal of Advanced Research
https://www.readbyqxmd.com/read/25685450/human-schistosomiasis-clinical-perspective-review
#13
REVIEW
Rashad S Barsoum, Gamal Esmat, Tamer El-Baz
The clinical manifestations of schistosomiasis pass by acute, sub acute and chronic stages that mirror the immune response to infection. The later includes in succession innate, TH1 and TH2 adaptive stages, with an ultimate establishment of concomitant immunity. Some patients may also develop late complications, or suffer the sequelae of co-infection with other parasites, bacteria or viruses. Acute manifestations are species-independent; occur during the early stages of invasion and migration, where infection-naivety and the host's racial and genetic setting play a major role...
September 2013: Journal of Advanced Research
https://www.readbyqxmd.com/read/25587481/bladder-perforation-secondary-to-primary-systemic-amyloidosis
#14
Christopher J Dru, Tom S Feng, Howard H Kim
Amyloidosis is a disorder of protein folding characterized by extracellular aggregation and deposition of amyloid protein fibrils. Light-chain amyloidosis, also known as primary systemic amyloidosis, is the most common form of the disease. We present a case of an 84-year-old male with a history of systemic primary amyloidosis causing genitourinary, cardiac, and autonomic dysfunction who presented with hematuria and hypotension secondary to bladder perforation. He underwent open repair of a large extraperitoneal bladder defect...
2014: Case Reports in Urology
https://www.readbyqxmd.com/read/25374907/primary-localized-amyloidosis-of-the-urinary-tract-frequently-mimics-neoplasia-a-clinicopathologic-analysis-of-11-cases
#15
Fang Zhou, Peng Lee, Ming Zhou, Jonathan Melamed, Fang-Ming Deng
Localized urinary tract amyloidosis (UTA) is a rare disease that mimics neoplasia clinically, cystoscopically, and radiologically. We report eleven cases of isolated UTA from the urinary bladder (n=7) and upper urinary tract including the ureter (n=2) and renal pelvis (n=2). All cases clinically presented as mass lesions prior to histologic examination and clinically suggested a neoplastic process. The amyloid composition in most cases was mixed Kappa and Lambda light chains. All cases were cured after surgical excision except one case which was diagnosed as plasmacytosis/plasmacytoma six months later...
2014: American Journal of Clinical and Experimental Urology
https://www.readbyqxmd.com/read/25366012/primary-bladder-amyloidosis
#16
Takaaki Kobayashi, John Roberts, Jeffrey Levine, Justin Degrado
Primary bladder amyloidosis is a rare disease, with only 200 cases reported worldwide. This condition is clinically important since it masquerades as a malignancy. We herein present a case of primary bladder amyloidosis presenting as painless hematuria and dysuria. Computed tomography and ultrasound showed thickening of the posterior bladder wall. Cystoscopy revealed abnormal bladder tissue suspicious of malignancy. However, transurethral resection of a bladder tumor showed no evidence of malignant cells. Amyloid was identified on Congo red staining...
2014: Internal Medicine
https://www.readbyqxmd.com/read/25241838/intractable-hematuria-secondary-to-systemic-amyloidosis-with-bladder-involvement
#17
Nelson Arturo Diez Calzadilla, José Antonio March Villalba, Adriana Canosa Fernández, Pilar Soriano Sarrió
OBJECTIVE: To present the therapeutic management of intractable hematuria secondary to systemic amyloidosis with bladder involvement. METHODS: We describe the clinical case, the medical management, the endo-urological technique used, and the results supported by relevant published literature. RESULTS: A 50-year-old woman with a 20-year history of rheumatoid arthritis in chronic treatment with corticosteroids and non-steroidal anti-inflammatory drugs in addition to chronic renal insufficiency not requiring hemodialysis...
September 2014: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/25098518/-successful-treatment-with-bortezomib-in-a-patient-with-systemic-primary-al-amyloidosis-manifesting-severe-gastrointestinal-bleeding
#18
Tori Ida, Kazunao Hayashi, Toru Ida, Satoko Hirano, Fumie Nakamura, Hirohito Sone, Masahiro Fujiwara
We present a systemic primary AL amyloidosis patient with severe gastrointestinal bleeding for whom treatment with bortezomib and dexamethasone was very effective. An 83-year-old woman was admitted to our hospital suffering from multiple gastric ulcers with bleeding. She had monoclonal protein (IgG, λ) in her serum. Systemic primary AL amyloidosis was diagnosed. She was also suspected of having amyloid deposition in cardiac muscle, as well as her bladder and intestinal mucosa. However, we were unable to carry out other invasive examinations due to her bleeding tendency...
July 2014: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/25061549/multiple-myeloma-associated-amyloidoma-of-the-sacrum-case-report-and-review-of-the-literature
#19
F M Klenke, C Wirtz, Y Banz, M J B Keel, N D Klass, U Novak, L M Benneker
Study Design Case report. Objectives With only two previously reported cases, localized amyloidosis of the sacrum is extremely rare. Here we report a 64-year-old woman with a large osteolytic lesion accompanied by weakness and paresthesia of the right leg and difficulties in bladder control. Methods Fine needle biopsy and standard staging procedures revealed a primary solitary amyloidoma that was treated with intralesional resection, lumbopelvic stabilization, and consolidation radiotherapy. Results Clinical follow-up revealed the diagnosis of multiple myeloma 9 months after initial treatment...
June 2014: Global Spine Journal
https://www.readbyqxmd.com/read/24892396/aa-type-primary-amyloidosis-of-the-urinary-bladder-clinical-case-and-bibliographic-review
#20
Jose David Jimenez-Parra, Diego Garcia-Gracia, Rosa Maria Guarch Troyas, Lorena Torres-Varas, Amaia Sotil Arrieta, Manuel Montesino Semper
OBJECTIVE: Amyloidosis is a disease characterised by deposition of eosinophilic hyaline material in different tissues. Urinary bladder involvement is uncommon with less than 200 cases of the primary form published in the literature. We present a new case of primary AA type amyloidosis of the urinary bladder (typical of secondary forms). METHODS: A 66-year-old male was seen in the outpatient urology consultation with several-weeks history intermittent haematuria with decreased voiding urinary calibre...
May 2014: Archivos Españoles de Urología
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