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Stasis dermatitis

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https://www.readbyqxmd.com/read/27910751/recent-advances-in-pharmacotherapeutic-paradigm-of-mild-to-recalcitrant-atopic-dermatitis
#1
Zahid Hussain, Shariza Sahudin, Hnin Ei Thu, Ahmad Nazrun Shuid, Syed Nasir Abbas Bukhari, Endang Kumolosasi
Atopic dermatitis (AD) is a common, chronic skin inflammatory disorder characterized by perivascular infiltration of immunoglobulin E (IgE), T lymphocytes, and mast cells. The key factors responsible for the pathophysiology of this disease are immunological disorders and defects in epidermal barrier properties. Pruritus, intense itching, psychological stress, deprived physical and mental performance, and sleep disturbance are the hallmark features of this dermatological disorder. Preventive interventions such as educational programs, avoidance of allergens, and exclusive care toward the skin could play a partial role in suppressing the symptoms...
2016: Critical Reviews in Therapeutic Drug Carrier Systems
https://www.readbyqxmd.com/read/27638234/the-death-of-balzac-1799-1850-and-the-treatment-of-heart-failure-during-the-nineteenth-century
#2
A Perciaccante, M A Riva, A Coralli, P Charlier, R Bianucci
Overweight, workaholic, and a caffeine abuser, Honoré de Balzac lived a life of excess. He prematurely died at the age of 51 owing to gangrene associated with congestive heart failure. Textual sources allow us to take a glimpse into his last 3 months of life. Because of ventricular hypertrophy, Balzac's respiratory conditions were appalling and he developed severe leg edemas and possibly stasis dermatitis. Here we report on Balzac's demise and provide first evidence of a pioneering medical treatment applied to save his life: the use of a trocar to drain leg edema...
September 13, 2016: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/27280438/isolation-and-characterization-of-an-atypical-metschnikowia-sp-strain-from-the-skin-scraping-of-a-dermatitis-patient
#3
Chee Sian Kuan, Rokiah Ismail, Zhenli Kwan, Su Mei Yew, Siok Koon Yeo, Chai Ling Chan, Yue Fen Toh, Shiang Ling Na, Kok Wei Lee, Chee-Choong Hoh, Wai-Yan Yee, Kee Peng Ng
A yeast-like organism was isolated from the skin scraping sample of a stasis dermatitis patient in the Mycology Unit Department of Medical Microbiology, University Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia. The isolate produced no pigment and was not identifiable using chromogenic agar and API 20C AUX. The fungus was identified as Metschnikowia sp. strain UM 1034, which is close to that of Metschnikowia drosophilae based on ITS- and D1/D2 domain-based phylogenetic analysis. However, the physiology of the strain was not associated to M...
2016: PloS One
https://www.readbyqxmd.com/read/27134709/a-case-of-patch-stage-of-kaposi-s-sarcoma-and-discussion-of-the-differential-diagnosis
#4
Ipshita Kak, Samih Salama, Gabriella Gohla, Asghar Naqvi, Salem Alowami
A 55 year old HIV positive male had a skin lesion biopsy which showed atypical vascular proliferation within the superficial and deep dermis with mild atypia of lining endothelial cells. A sparse lymphoplasmacytic infiltrate surrounding the irregular vascular channels was noted. Immunohistochemistry highlighted the atypical blood vessels with the vascular markers CD31, CD34 and Factor VIII. The differential diagnosis included unusual vascular or lymphatic proliferations, stasis dermatitis, kaposiform hemangioendothelioma, progressive lymphangioma and angiosarcoma with focal Kaposi's sarcoma features...
March 21, 2016: Rare Tumors
https://www.readbyqxmd.com/read/26724880/dermatological-complaints-of-the-elderly-attending-a-dermatology-outpatient-clinic-in-turkey-a-prospective-study-over-a-one-year-period
#5
Muhterem Polat, Mustafa N İlhan
The geriatric population is continuously growing, which leads to more aged patients being admitted to dermatology clinics. The aim of this study is to determine the dermatological complaints of the elderly attending a dermatology outpatient clinic. All of the patients aged 65 years and older admitted to our dermatology outpatient clinic over a 1-year period were included. Patients were divided into 2 groups according to their ages as group I (65-74 years) and group II (≥75 years). The patients were asked about their dermatologic complaints...
2015: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/26375218/physiological-and-lifestyle-factors-contributing-to-risk-and-severity-of-peri-orbital-dark-circles-in-the-brazilian-population
#6
Mary S Matsui, Sérgio Schalka, Garrett Vanderover, Christina G Fthenakis, J Christopher, Patricia Camarano Pinto Bombarda, Juliana Regina Bueno, Bianca Lenci Inácio Viscomi, Mário Sérgio Bombarda Júnior
BACKGROUND: Peri-orbital dark circles are a cosmetic concern worldwide, and have been attributed to hyperpigmentation from allergy or atopic dermatitis, blood stasis, structural shadowing effects, and a thin epidermis/dermis under the eye. It is of interest to better understand lifestyle and demographic risk factors and the relative impact of melanin, blood and epidermal/dermal factors on the severity of Peri-orbital dark circles. OBJECTIVE: To compare by non-invasive imaging the impact of biological factors to a visual grading scale for Peri-orbital dark circles, and test the correlation of various demographic factors with Peri-orbital dark circles...
July 2015: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/26285897/-contact-allergies-in-the-elderly
#7
V Mahler
The percentage of seniors (> 65 years of age) in the general population continues to rise. Their sensitization profile may be influenced by lifelong work-related and nonwork-related exposures and comorbidities requiring local or systemic treatment. Recent analysis of the IVDK (Information Network of Departments of Dermatology) cohort concerning the most frequently recognized contact allergens in the age group above 65 (2009-2013: N = 14,841) revealed significant differences compared to the age group up to 65 years of age...
September 2015: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/26242240/clinical-and-microbiological-characteristics-of-purulent-and-non-purulent-cellulitis-in-hospitalized-taiwanese-adults-in-the-era-of-community-associated-methicillin-resistant-staphylococcus-aureus
#8
Chun-Yuan Lee, Hung-Chin Tsai, Calvin M Kunin, Susan Shin-Jung Lee, Yao-Shen Chen
BACKGROUND: The risk factors, microbial etiology, differentiation, and clinical features of purulent and non-purulent cellulitis are not well defined in Taiwan. METHODS: We conducted a retrospective cohort study of hospitalized adults with cellulitis in Taiwan in 2013. The demographic characteristics, underlying diseases, clinical manifestations, laboratory and microbiological findings, treatments, and outcomes were compared for patients with purulent and non-purulent cellulitis...
2015: BMC Infectious Diseases
https://www.readbyqxmd.com/read/26228826/stasis-papillomatosis-with-cardiac-complications-and-vein-insufficiency
#9
Tomasz Zubilewicz, Wojciech Brzozowski, Grazyna Orlicz-Szczesna, Marek Ilzecki, Bartlomiej Wawrzycki, Monika Podhorecka, Ewa Dybiec, Witold Krupski, Aldona Pietrzak
We report the case of a 73-year-old man with massive swelling of the lower extremities, with a chronic and rather uncommon form of stasis dermatitis - stasis papillomatosis. The patient was also diagnosed with severe heart failure, including dilated cardiomyopathy, hypothyroidism that required a substantial dose of exogenous tyrosine, microcytic and megaloblastic anemia, iron deficiency, and type 2 diabetes. The cause of stasis dermatitis lesions is not completely understood. It may be caused by the allergic reaction to some epidermal protein antigen formation or chronic damage to the dermal-epidermal barrier that makes the skin more sensitive to irritants or trauma...
2015: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/26125221/non-hiv-related-kaposi-sarcoma-in-2-hispanic-patients-arising-in-the-setting-of-chronic-venous-insufficiency
#10
Syril Kt Que, Taylor DeFelice, Farah R Abdulla, David Cassarino, Rishi R Patel
Kaposi sarcoma (KS) is a vascular neoplasm associated with human herpesvirus 8 (HHV-8) infection that can be confused with the clinical and histological findings of chronic venous insufficiency. Definitive diagnosis of KS can only be achieved by performing a polymerase chain reaction for HHV-8 or by immunostaining for the HHV-8 antigen. We describe 2 unusual clinical presentations of KS in the setting of chronic venous insufficiency with clinical and histologic features consistent with stasis dermatitis but positive HHV-8 immunostaining...
June 2015: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/25972026/venous-status-ulcers-due-to-congenital-agenesis-of-the-inferior-vena-cava-in-a-16-year-old-male
#11
J Phair, E Trestman, J Stableford
We report a case of agenesis of the infrarenal inferior vena cava in a 16-year-old male presenting with venous stasis dermatitis and ulceration in the gaiter region bilaterally. Duplex imaging was performed revealing absence of infrarenal inferior vena cava and iliofemoral venous system. Magnetic resonance venography then confirmed the above findings along with revealing extensive lumbar and pelvic collateralization. This patient's condition has been successfully managed conservatively with compression therapy and wound care...
February 2016: Vascular
https://www.readbyqxmd.com/read/25945283/keratinocyte-migration-and-a-hypothetical-new-role-for-extracellular-heat-shock-protein-90-alpha-in-orchestrating-skin-wound-healing
#12
David T Woodley, Ashley Wysong, Brittany DeClerck, Mei Chen, Wei Li
Significance: The treatment and care of patients with skin wounds are a major healthcare expenditure. Burn wounds, iatrogenic surgical wounds, venous stasis dermatitis ulcers, diabetic lower limb ulcers, pressure ulcers, and skin wounds from peripheral neuropathies are largely treated with only supportive care. Despite a great deal of research into using growth factors as therapeutic agents, to date, the field has been disappointing. The only biologic agent that is Federal Drug Administration (FDA) approved for promoting skin wound healing is recombinant platelet-derived growth factor (PDGF-BB), but its modest efficacy and expense limit its use clinically...
April 1, 2015: Advances in Wound Care
https://www.readbyqxmd.com/read/25763242/new-therapy-using-omega-3-acid-ethyl-esters-for-decubitus-ulcers-and-stasis-dermatitis-a-case-report
#13
Kazuki Nagai, Katsuhiko Matsumaru, Ikuko Hirai, Yujiro Takae, Kazuo Andoh
INTRODUCTION: In daily practice, it is common to experience difficulty in treating decubitus ulcers (pressure ulcers, also known as decubitus ulcers) and stasis dermatitis of the lower limbs. We hereby report that omega-3-acid ethyl esters were remarkably effective when administered to cases of refractory pressure ulcers and stasis dermatitis for the purpose of improving the blood flow and promoting blood circulation. CASE PRESENTATION: Case 1: A 21-year-old Japanese female with lower-body paralysis...
December 2014: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/25706926/risk-factors-associated-with-a-reduced-response-in-the-treatment-of-erysipelas
#14
Miriam Linke, Nina Booken
BACKGROUND: In most cases, erysipelas may be adequately treated using first-line antibiotic therapy. However, clinicians are sometimes confronted with complicated cases, in which patients do not respond to initial antibiotic therapy. The objective of this study was to identify risk factors associated with a reduced response to antibiotic therapy and, thus, a more complicated disease course. PATIENTS AND METHODS: We retrospectively analyzed the clinical course of 98 patients with erysipelas treated with standard antibiotic therapy...
March 2015: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/25693757/chronic-pruritus-in-the-elderly-pathophysiology-diagnosis-and-management
#15
REVIEW
Rodrigo Valdes-Rodriguez, Carolyn Stull, Gil Yosipovitch
Chronic itch in the elderly is a common problem, with a significant impact on quality of life and sleep in elderly patients. Chronic itch may be attributable to several causes, including dry skin, immunosenescence and neural degeneration. Itch may also be caused by skin diseases, such as seborrhoeic dermatitis and stasis dermatitis; systemic conditions, such as end-stage renal disease and diabetes; and psychogenic conditions, such as depression and anxiety. The use of polypharmacy may also cause itch, with or without a rash...
March 2015: Drugs & Aging
https://www.readbyqxmd.com/read/25209826/-stasis-dermatitis-and-levofloxacin
#16
J-L Schmutz, P Tréchot
No abstract text is available yet for this article.
August 2014: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/25160098/the-immunocompromised-district-in-dermatology-a-unifying-pathogenic-view-of-the-regional-immune-dysregulation
#17
Vincenzo Ruocco, Eleonora Ruocco, Vincenzo Piccolo, Giampiero Brunetti, Luigi Pio Guerrera, Ronni Wolf
Besides the systemic immune deficiency, a sectorial default in immune control may occur in immunocompetent subjects. This regional immune defect can appear and remain confined to differently damaged skin areas, lately labeled immunocompromised districts (ICDs). An ICD is a skin area more vulnerable than the rest of the body for genetic or acquired reasons. Its vulnerability mainly consists in a local dysregulation of the immune control, which often facilitates (but sometimes hinders) the local onset of immunity-related eruptions or skin disorders...
September 2014: Clinics in Dermatology
https://www.readbyqxmd.com/read/25102574/identifying-the-causes-of-contact-dermatitis
#18
Ruth Jones, Helen M Horn
Contact dermatitis results from skin contact with an exogenous substance. It can be caused by direct contact, airborne particles, vapours or light. Individuals of any age can be affected. The two most common variants are irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD). ICD is more common and has a worse prognosis. Other less common forms of contact dermatitis include photocontact allergy and, in food handlers, protein contact dermatitis. ICD is a form of eczema and is induced by direct inflammatory pathways without prior sensitisation...
June 2014: Practitioner
https://www.readbyqxmd.com/read/24894790/pseudo-kaposi-sarcoma-worsening-after-leg-vein-harvest-for-coronary-artery-bypass-grafting
#19
Hind Alshihry, Muzamil Amin Chisti, Issam Hamadah
Acroangiodermatitis (AAD) (synonym, pseudo-Kaposi sarcoma) is a term that encompasses 2 different conditions: (1) AAD of Mali, which refers to skin lesions that mainly develop bilaterally on the lower extremities of patients with chronic venous insufficiency and is an extreme form of stasis dermatitis and (2) Stewart-Bluefarb syndrome, which consists of an arteriovenous malformation that mainly affects the limbs of young patients unilaterally. We present a case of a 68-year-old lady with progressive skin lesions on both lower limbs (right > left) as a result of chronic venous insufficiency that became worse after the leg-vein harvest for coronary artery bypass grafting was taken from the right leg...
March 2014: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/24703505/prevalence-and-associated-factors-of-comorbid-skin-diseases-in-patients-with-schizophrenia-a-clinical-survey-and-national-health-database-study
#20
Bai-Yao Wu, Bo-Jian Wu, Shin-Min Lee, Hsiao-Ju Sun, Yun-Ting Chang, Ming-Wei Lin
OBJECTIVES: To examine the epidemiology of and possible risk factors for skin diseases in patients with schizophrenia. METHODS: All of 337 patients with schizophrenia were recruited from the therapeutic community of a psychiatric hospital and underwent a detailed skin examination. The National Health Insurance Research Database (NHIRD) was used to compare the prevalence of skin diseases between patients with schizophrenia and those without. RESULTS: In the clinical survey, fungal infection (61...
July 2014: General Hospital Psychiatry
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