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Fibromyalgia and chronic fatigue

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https://www.readbyqxmd.com/read/28925285/longitudinal-outcomes-associated-with-significant-other-responses-to-chronic-fatigue-and-pain
#1
Karen B Schmaling, Jessica L Fales, Sterling McPherson
This study investigated significant others' behavior associated with fatigue, pain, and mental health outcomes among 68 individuals with chronic fatigue (43% also had fibromyalgia) over 18 months. More negative significant others' responses were associated with more pain, poorer physical and mental health, and more fatigue-related symptoms over time. More fibromyalgia tender points covaried with more solicitous significant others' responses over time. Better mental health covaried with more distracting significant others' responses over time...
September 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28914723/inducing-somatic-symptoms-in-functional-syndrome-patients-effects-of-manipulating-state-negative-affect
#2
Maaike Van Den Houte, Katleen Bogaerts, Ilse Van Diest, Jozef De Bie, Philippe Persoons, Lukas Van Oudenhove, Omer Van den Bergh
OBJECTIVE: Induction of negative affective states can enhance bodily symptoms in high habitual symptom reporters among healthy persons, and in patients with irritable bowel syndrome. The aim of this study was to replicate this effect in patients with fibromyalgia and chronic fatigue syndrome and to investigate the role of moderators, focusing on alexithymia, negative affectivity (NA) and absorption. METHODS: Patients with fibromyalgia and/or chronic fatigue syndrome (N=81) and healthy controls (HC, N=41) viewed series of neutral, positive and negative affective pictures...
September 13, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28903778/jtm-advances-in-uncharted-territories-diseases-and-disorders-of-unknown-etiology
#3
EDITORIAL
Monica C Panelli
We are delighted to announce a new section in the Journal of Translational Medicine, 'Illnesses of Unknown Etiology'. This section aims to provide a translational medicine forum for the publication of research on illnesses, multisystem diseases and syndromes of unknown etiology. Examples of these include Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia Syndrome.
September 13, 2017: Journal of Translational Medicine
https://www.readbyqxmd.com/read/28860106/web-based-mindfulness-interventions-for-people-with-physical-health-conditions-systematic-review
#4
Kirsti I Toivonen, Kristin Zernicke, Linda E Carlson
BACKGROUND: Mindfulness-based interventions (MBIs) are becoming increasingly popular for helping people with physical health conditions. Expanding from traditional face-to-face program delivery, there is growing interest in Web-based application of MBIs, though Web-based MBIs for people with physical health conditions specifically have not been thoroughly reviewed to date. OBJECTIVE: The objective of this paper was to review Web-based MBIs for people with physical health conditions and to examine all outcomes reported (eg, efficacy or effectiveness for physical changes or psychological changes; feasibility)...
August 31, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28843450/symptoms-of-chronic-fatigue-syndrome-myalgic-encephalopathy-are-not-determined-by-activity-pacing-when-measured-by-the-chronic-pain-coping-inventory
#5
D P Thompson, D Antcliff, S R Woby
OBJECTIVES: Chronic fatigue syndrome/myalgic encephalopathy (CFS/ME) is a chronic illness which can cause significant fatigue, pain and disability. Activity pacing is frequently advocated as a beneficial coping strategy, however, it is unclear whether pacing is significantly associated with symptoms in people with CFS/ME. The first aim of this study was therefore to explore the cross-sectional associations between pacing and levels of pain, disability and fatigue. The second aim was to explore whether changes in activity pacing following participation in a symptom management programme were related to changes in clinical outcomes...
August 4, 2017: Physiotherapy
https://www.readbyqxmd.com/read/28799194/comparison-of-sleep-structure-and-psychometric-profiles-in-patients-with-fibromyalgia-osteoarthritis-and-healthy-controls
#6
Wai K Yeung, Kevin Morgan, Frank Mckenna
While research indicates that both the macro- and microstructure of sleep may be altered in fibromyalgia syndrome, few studies have controlled for symptom duration or included pain-control participants (i.e. patients with chronic pain and sleep disturbance not associated with fibromyalgia syndrome). A frequently reported alteration found in the sleep microstructure of patients with fibromyalgia syndrome is the alpha-delta sleep anomaly. Although alpha waves have been observed during N3 sleep in healthy individuals, it has been proposed that there is an increase in alpha wave activity during slow-wave sleep in fibromyalgia syndrome...
August 11, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28766982/serum-met-5-enkephalin-levels-are-reduced-in-multiple-sclerosis-and-restored-by-low-dose-naltrexone
#7
Michael D Ludwig, Ian S Zagon, Patricia J McLaughlin
Low-dose naltrexone is a widely used off-label therapeutic prescribed for a variety of immune-related disorders. The mechanism underlying low-dose naltrexone's efficacy for fatigue, Crohn's disease, fibromyalgia, and multiple sclerosis is, in part, intermittent blockade of opioid receptors followed by upregulation of endogenous opioids. Short, intermittent blockade by naltrexone specifically blocks the opioid growth factor receptor resulting in biofeedback events that increase production of the endogenous opioid growth factor (OGF) (chemically termed [Met(5)]-enkephalin) facilitating interactions between opioid growth factor and opioid growth factor receptor that ultimately, result in inhibited cell proliferation...
January 1, 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28758313/altered-theta-oscillations-in-resting-eeg-of-fibromyalgia-syndrome-patients
#8
N Fallon, Y Chiu, T Nurmikko, A Stancak
BACKGROUND: Fibromyalgia syndrome (FM) is a chronic pain disorder characterized by widespread pain, sleep disturbance, fatigue and cognitive/affective symptoms. Functional imaging studies have revealed that FM and other chronic pain syndromes can affect resting brain activity. This study utilized electroencephalographic (EEG) recordings to investigate the relative power of ongoing oscillatory activity in the resting brain. METHODS: A 64-channel EEG was recorded at rest in 19 female FM patients and 18 healthy, age-matched, control subjects...
July 31, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28722815/influence-of-morphine-and-naloxone-on-pain-modulation-in-rheumatoid-arthritis-chronic-fatigue-syndrome-fibromyalgia-and-controls-a-double-blind-randomized-placebo-controlled-cross-over-study
#9
Linda Hermans, Jo Nijs, Patrick Calders, Luc De Clerck, Greta Moorkens, Guy Hans, Sofie Grosemans, Tine Roman De Mettelinge, Joanna Tuynman, Mira Meeus
BACKGROUND: Impaired pain inhibitory and enhanced pain facilitatory mechanisms are repeatedly reported in patients with central sensitization pain. However, the exact effects of frequently prescribed opioids on central pain modulation are still unknown. METHODS: A randomized, double-blind, placebo-controlled cross-over trial was carried out. Ten CFS/FM patients, 11 RA patients and 20 controls were randomly allocated to the experimental (10 mg morphine or 0.2 mg/ml Naloxone) and placebo (2 ml Aqua) group...
July 19, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28713879/examining-those-meeting-iom-criteria-versus-iom-plus-fibromyalgia
#10
Leonard A Jason, Stephanie McManimen, Madison Sunnquist, Julia L Newton, Elin Bolle Strand
The Institute of Medicine (IOM) recently developed clinical criteria for chronic fatigue syndrome (CFS). There might be additional criteria that could select a more homogenous and impaired group of patients, particularly those with pain. The current study focused on criteria which involved meeting the four IOM criteria, excluding medical and psychiatric co-morbidities, along with having fibromyalgia (FM). Findings indicated that those meeting the IOM clinical criteria plus FM were more impaired on a wide variety of symptoms and functional areas than those meeting on the IOM criteria or those with just 6 months of fatigue...
2017: Neurology (E-Cronicon)
https://www.readbyqxmd.com/read/28681715/motor-cortex-trns-improves-pain-affective-and-cognitive-impairment-in-patients-with-fibromyalgia-preliminary-results-of-a-randomised-sham-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Massimiliano Curatolo, Giuseppe La Bianca, Giuseppe Cosentino, Roberta Baschi, Giuseppe Salemi, Rossella Talotta, Marcello Romano, Giovanni Triolo, Marina De Tommaso, Brigida Fierro, Filippo Brighina
OBJECTIVES: Fibromyalgia (FM) is a clinical syndrome characterised by widespread musculoskeletal pain, chronic fatigue, cognitive deficits, and sleep and mood disorders. The effectiveness of most pharmacological treatments is limited, and there is a need for new, effective and well-tolerated therapies. It has recently been shown that transcranial direct-current stimulation (tDCS) of the motor cortex reduces pain, and that tDCS of the dorso-lateral prefrontal cortex (DLPFC) improves anxiety, depression and cognitive impairment in FM patients...
May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28681712/one-year-in-review-2017-fibromyalgia
#12
REVIEW
Rossella Talotta, Laura Bazzichi, Manuela Di Franco, Roberto Casale, Alberto Batticciotto, Maria Chiara Gerardi, Piercarlo Sarzi-Puttini
Fibromyalgia (FM) is a complex syndrome characterised by chronic pain, fatigue and functional symptoms. Widespread pain is often its most typical feature, whereas other manifestations may be associated to various extents. Its aetiopathogenesis is still a matter of debate, but various pharmacological and non-pharmacological therapies are currently available for its treatment. We review the literature concerning the most recent findings relating to the aetiopathogenesis, assessment and treatment of FM published between January 2016 and January 2017...
May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28681709/current-trends-in-disability-claims-due-to-fibromyalgia-syndrome
#13
REVIEW
Vittorio Schweiger, Giovanna Del Balzo, Dario Raniero, Domenico De Leo, Alvise Martini, Piercarlo Sarzi-Puttini, Enrico Polati
Fibromyalgia syndrome (FMS) affects 0.4-8% of the general population predominantly in the female population with a F:M ratio of 3-9:1. It is characterised by persistent widespread pain and other associated clinical conditions such as chronic fatigue, irritable bowel syndrome (IBS), temporomandibular joint dysfunction (TMJD), sleep disorders and cognitive impairment. FMS diagnosis at present is purely clinical because no medical or laboratory examinations are able to identify it with certainty. FMS is not fully recognised worldwide, and patients often do not receive the treatment and disability benefits planned for other chronic diseases even though it gives rise to a very significant social burden due to direct and indirect healthcare costs and the loss of productivity and work...
May 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28665159/new-drugs-or-alternative-therapy-to-blurring-the-symptoms-of-fibromyalgia-a-patent-review
#14
REVIEW
Marlange A Oliveira, Adriana G Guimarães, Adriano A S Araújo, Lucindo J Quintans-Júnior, Jullyana S S Quintans
Fibromyalgia (FM) is a musculoskeletal condition characterized by chronic widespread pain, tenderness and often accompanied by other comorbid conditions such as depression, anxiety, chronic fatigue, among others. Now, we aimed to survey the recent patents describing new drugs or alternative therapy for FM. Areas covered: This review covers the therapeutic patents published between 2010 and 2017 from specialized search databases (WIPO, DERWENT, INPI, ESPANET and USPTO) that report the discovery of new drugs or pharmacologic alternative for the treatment of FM...
October 2017: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/28661421/oral-supplementation-of-melatonin-protects-against-fibromyalgia-related-skeletal-muscle-alterations-in-reserpine-induced-myalgia-rats
#15
Gaia Favero, Valentina Trapletti, Francesca Bonomini, Alessandra Stacchiotti, Antonio Lavazza, Luigi Fabrizio Rodella, Rita Rezzani
Fibromyalgia is a chronic syndrome characterized by widespread musculoskeletal pain and an extensive array of other symptoms including disordered sleep, fatigue, depression and anxiety. Important factors involved in the pathogenic process of fibromyalgia are inflammation and oxidative stress, suggesting that ant-inflammatory and/or antioxidant supplementation might be effective in the management and modulation of this syndrome. Recent evidence suggests that melatonin may be suitable for this purpose due to its well known ant-inflammatory, antioxidant and analgesic effects...
June 29, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28658097/a-thermal-dysregulation-problem-after-breast-cancer-surgery-what-could-be
#16
Diana Rüstemova, Aysun Genc, Gül Bora, Birkan Sonel Tur
RATIONALE: Chronic fatigue syndrome (CFS) is a complicated disorder characterized by severe fatigue that is not relieved with rest and associated with physical symptoms such as sleep problems, headache, muscle pain, or joint pain. PATIENT CONCERNS: Forty-one year old patient complained from feeling cold after breast cancer surgery. DIAGNOSES: The diagnoses of fibromyalgia, depression, neurological, psychiatric, and vascular disorders were excluded by appropriate clinical and laboratory investigations...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28646319/presence-of-enthesopathy-in-patients-with-primary-sjogren-s-syndrome-ultrasonographic-study-of-a-local-cohort
#17
Sinem Sag, Mustafa Serdar Sag, Ibrahim Tekeoglu, Ayhan Kamanlı, Kemal Nas
BACKGROUND: Musculoskeletal findings in Sjögren's syndrome are arthralgia, arthritis, myalgia, myositis, fibromyalgia, and chronic fatigue. Enthesis zones are important in the formation of pain in the musculoskeletal system. Musculoskeletal ultrasound (US) may show subclinical enthesitis in the synovial joints and in the axial skeleton before joint swelling in inflammatory diseases characterized by arthritis. OBJECTIVE: In this study, we aimed to determine the presence of enthesopathy using the Madrid sonographic enthesitis index (MASEI) in patients with primary Sjögren's syndrome (PSS)...
June 23, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28623933/transferring-research-from-a-university-to-the-united-kingdom-national-health-service-the-implications-for-impact
#18
Helen Payne
The aim of this article is to inform readers of the author's reflections on the experience of transferring university-based research into the commercial sector, and of the processes and strategies employed when preparing for impact in so doing. Concepts for the transfer are illustrated by the author's reflection on aspects that arose during the birthing and subsequent start-up of a university spin-off, Pathways2Wellbeing, a form of reflection-on-action. This is the vehicle for the adaption required to transfer research into the delivery of a specialised clinic in the United Kingdom National Health Service for people with medically unexplained, persistent, bodily symptoms such as fibromyalgia, chronic fatigue and chronic pain...
June 17, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28614420/the-degree-of-cardiac-baroreflex-involvement-during-active-standing-is-associated-with-the-quality-of-life-in-fibromyalgia-patients
#19
Antonio Roberto Zamunér, Alberto Porta, Carolina Pieroni Andrade, Meire Forti, Andrea Marchi, Raffaello Furlan, Franca Barbic, Aparecida Maria Catai, Ester Silva
Fibromyalgia syndrome (FMS) is a rheumatologic disorder characterized by chronic widespread pain, fatigue and other symptoms. Baroreflex dysfunction has been observed in women with FMS. However, it is unknown whether the limited involvement of the baroreflex control during an orthostatic stimulus has some impact on the quality of life of the FMS patient. Therefore, the aim of the study is evaluate the relationship between the quality of life of the FMS patient and indexes of the cardiovascular autonomic control as estimated from spontaneous fluctuations of heart period (HP) and systolic arterial pressure (SAP)...
2017: PloS One
https://www.readbyqxmd.com/read/28605207/kinesiophobia-and-maladaptive-coping-strategies-prevent-improvements-in-pain-catastrophizing-following-pain-neuroscience-education-in-fibromyalgia-chronic-fatigue-syndrome-an-explorative-study
#20
Anneleen Malfliet, Jessica Van Oosterwijck, Mira Meeus, Barbara Cagnie, Lieven Danneels, Mieke Dolphens, Ronald Buyl, Jo Nijs
Many patients with chronic fatigue syndrome(CFS) and/or fibromyalgia(FM) have little understanding of their condition, leading to maladaptive pain cognitions and coping strategies. These should be tackled during therapy, for instance by pain neurophysiology education (PNE). Although positive effects of PNE are well-established, it remains unclear why some patients benefit more than others. This paper aims at exploring characteristics of patients responding poor to PNE to further improve its effectiveness. Data from two RCT's were pooled to search for baseline predictors...
June 12, 2017: Physiotherapy Theory and Practice
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