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Electronic nicotine delivery system

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https://www.readbyqxmd.com/read/28522563/biomarkers-of-exposure-to-new-and-emerging-tobacco-and-nicotine-delivery-products
#1
Suzaynn F Schick, Benjamin C Blount, Peyton Jacob, Najat A Saliba, John T Bernert, Ahmad El Hellani, Peter Jatlow, R Steve Pappas, Lanqing Wang, Jonathan Foulds, Arunava Ghosh, Stephen S Hecht, John C Gomez, Jessica R Martin, Clementina Mesaros, Sanjay Srivastava, Gideon St Helen, Robert Tarran, Pawel K Lorkiewicz, Ian A Blair, Heather L Kimmel, Claire M Doerschuk, Neal L Benowitz, Aruni Bhatnagar
Accurate and reliable measurements of exposure to tobacco products are essential for identifying and confirming patterns of tobacco product use and for assessing their potential biological effects in both human populations and experimental systems. Due to the introduction of new tobacco-derived products and the development of novel ways to modify and use conventional tobacco products, precise and specific assessments of exposure to tobacco are now more important than ever. Biomarkers that were developed and validated to measure exposure to cigarettes are being evaluated to assess their utility for measuring exposure to these new products...
May 18, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28501385/full-and-partial-thickness-burns-from-spontaneous-combustion-of-e-cigarette-lithium-ion-batteries-with-review-of-literature
#2
Daniela Treitl, Rachele Solomon, Dafney L Davare, Rafael Sanchez, Chauniqua Kiffin
BACKGROUND: In recent years, the use of electronic cigarettes (e-cigarettes) has increased worldwide. Most electronic nicotine delivery systems use rechargeable lithium-ion batteries, which are relatively safe, but in rare cases these batteries can spontaneously combust, leading to serious full and partial thickness burn injuries. Explosions from lithium-ion batteries can cause a flash fire and accelerant-related burn injuries. CASE REPORT: A retrospective chart review was conducted of 3 patients with lithium-ion battery burns seen at our Level I community-based trauma center...
May 10, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28483810/evidentiary-support-in-public-comments-to-the-fda-s-center-for-tobacco-products
#3
Natalie Hemmerich, Elizabeth G Klein, Micah Berman
Electronic Nicotine Delivery Systems (ENDS) were introduced into the US market in 2007, and until recently these devices were unregulated at the federal level. In 2014, the US Food and Drug Administration (FDA) published a Notice of Proposed Rulemaking asserting its intention to regulate ENDS and requesting public comments on numerous related issues, including potential limits on the sale of flavored ENDS. This article analyzes key comments submitted to the FDA on the issue of flavor regulation in ENDS and examines the weight and credibility of the evidence presented by both supporters and opponents of regulation...
May 8, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28482017/evaluation-of-nicotine-pharmacokinetics-and-subjective-effects-following-use-of-a-novel-nicotine-delivery-system
#4
Axel Teichert, Patrick Brossard, Loyse Felber Medlin, Larissa Sandalic, Mikael Franzon, Chris Wynne, Murray Laugesen, Frank Lüdicke
Introduction: Novel nicotine delivery systems represent an evolving part of the tobacco harm reduction strategy. The pharmacokinetic (PK) profile of nicotine delivered by P3L, a pulmonary nicotine delivery system, and its effects on smoking urges and craving relief in relation to Nicorette® inhalator were evaluated. Methods: This open-label, ascending nicotine levels study was conducted in 16 healthy smokers. Three different nicotine delivery levels, 50, 80, and 150 µg/puff delivered by the P3L system were evaluated consecutively on different days, after the use of the Nicorette® inhalator...
May 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28460123/use-of-electronic-cigarettes-leads-to-significant-beta2-nicotinic-acetylcholine-receptor-occupancy-evidence-from-a-pet-imaging-study
#5
Stephen R Baldassarri, Ansel T Hillmer, Jon Mikael Anderson, Peter Jatlow, Nabeel Nabulsi, David Labaree, Kelly P Cosgrove, Stephanie S O'Malley, Thomas Eissenberg, Suchitra Krishnan-Sarin, Irina Esterlis
Background: Electronic cigarettes (ECs) can influence nicotine addiction by delivering aerosolized nicotine. We investigated if nicotine from ECs is delivered to the brain β2*-nicotinic-acetylcholine receptors (β2*-nAChR) and how this relates to the behavioral effects and nicotine delivery from cigarettes. Methods: Seven nicotine users participated in positron emission tomography (PET) studies with (-)-[18F]Flubatine before and after nicotine challenge with 0, 8 mg/ml, and 36 mg/ml nicotine in a 3...
April 29, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28392919/respiratory-bronchiolitis-associated-interstitial-lung-disease-secondary-to-electronic-nicotine-delivery-system-use-confirmed-with-open-lung-biopsy
#6
Mark Flower, Lakshmy Nandakumar, Mahendra Singh, David Wyld, Morgan Windsor, David Fielding
As a modern phenomenon, there is currently limited understanding of the possible toxic effects and broader implications of electronic nicotine delivery systems (ENDS). Large volumes of aerosolized particles are inhaled during "vaping" and there are now an increasing number of case reports demonstrating toxic effects of ENDS, as well as human studies demonstrating impaired lung function in users. This article presents a case of respiratory bronchiolitis interstitial lung disease (RB-ILD) precipitated by vaping in a 33-year-old male with 10 pack years of traditional cigarette and prior treatment for mixed germ cell tumour...
May 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28365587/electronic-nicotine-delivery-system-ends-use-during-smoking-cessation-a-qualitative-study-of-40-oklahoma-quitline-callers
#7
Katrina A Vickerman, Laura A Beebe, Gillian L Schauer, Brooke Magnusson, Brian A King
OBJECTIVES: Approximately 10% (40 000) of US quitline enrollees who smoke cigarettes report current use of electronic nicotine delivery systems (ENDS); however, little is known about callers' ENDS use. Our aim was to describe why and how quitline callers use ENDS, their beliefs about ENDS and the impact of ENDS use on callers' quit processes and use of FDA-approved cessation medications. DESIGN: Qualitative interviews conducted 1-month postregistration. Interviews were recorded, transcribed, double-coded and analysed to identify themes...
April 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28339800/the-dark-cloud-of-recreational-drugs-and-vaping
#8
M S Blundell, P I Dargan, D M Wood
Electronic cigarettes (e-cigarettes) are increasing in popularity with 19% of UK smokers reporting to have used them. The ability to regulate the evaporation temperature in newer electronic nicotine delivery systems (ENDS) facilitates the potential for use of these devices to 'vape' cannabis, novel psychoactive substances (NPS) and other recreational drugs. Vaping cannabis does have the potential to reduce tobacco use and combustible cannabis/tobacco-related disease, but with over one-third of UK adults reporting life-time use of recreational drugs and increasing e-cigarette uptake in adolescent groups the misuse of these devices poses a serious potential public health risk...
March 9, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28270392/qualitative-analysis-of-young-adult-ends-users-expectations-and-experiences
#9
Janet Hoek, Johannes Thrul, Pamela Ling
OBJECTIVES: Despite extensive research into the determinants of electronic nicotine delivery system (ENDS) uptake, few studies have examined the psychosocial benefits ENDS users seek and experience. Using a consumer ritual framework, we explored how ENDS users recreated or replaced smoking practices, and considered implications for smoking cessation. DESIGN: In-depth interviews; data analysed using thematic analysis. SETTING: Dunedin, New Zealand...
March 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28248987/why-do-people-use-electronic-nicotine-delivery-systems-electronic-cigarettes-a-content-analysis-of-twitter-2012-2015
#10
John W Ayers, Eric C Leas, Jon-Patrick Allem, Adrian Benton, Mark Dredze, Benjamin M Althouse, Tess B Cruz, Jennifer B Unger
The reasons for using electronic nicotine delivery systems (ENDS) are poorly understood and are primarily documented by expensive cross-sectional surveys that use preconceived close-ended response options rather than allowing respondents to use their own words. We passively identify the reasons for using ENDS longitudinally from a content analysis of public postings on Twitter. All English language public tweets including several ENDS terms (e.g., "e-cigarette" or "vape") were captured from the Twitter data stream during 2012 and 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28235965/electronic-nicotine-delivery-systems-and-or-electronic-non-nicotine-delivery-systems-for-tobacco-smoking-cessation-or-reduction-a-systematic-review-and-meta-analysis
#11
Regina El Dib, Erica A Suzumura, Elie A Akl, Huda Gomaa, Arnav Agarwal, Yaping Chang, Manya Prasad, Vahid Ashoorion, Diane Heels-Ansdell, Wasim Maziak, Gordon Guyatt
OBJECTIVE: A systematic review and meta-analysis to investigate the impact of electronic nicotine delivery systems (ENDS) and/or electronic non-nicotine delivery systems (ENNDS) versus no smoking cessation aid, or alternative smoking cessation aids, in cigarette smokers on long-term tobacco use. DATA SOURCES: Searches of MEDLINE, EMBASE, PsycInfo, CINAHL, CENTRAL and Web of Science up to December 2015. STUDY SELECTION: Randomised controlled trials (RCTs) and prospective cohort studies...
February 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28199725/electronic-nicotine-delivery-systems-ends-mapping-the-indian-online-retail-market
#12
Vikrant R Mohanty, Puneet Chahar, Aswiniy Y B, Vipul Yadav
No abstract text is available yet for this article.
February 11, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28198993/a-debate-can-we-recommend-electronic-cigarettes-to-our-patients-opinion-2
#13
Michał Poznański, Tadeusz Pietras, Adam Antczak
Electronic cigarettes are more and more frequently used to deliver nicotine. They are used both by the users of regular cigarettes and those who to date have not smoked. The literature about potential impact of electronic nicotine delivery systems on health is constantly growing. Particular concern is expressed about toxicity of chemical compounds and elements delivered with the vapour of electronic cigarettes. It turns out that products that have positive image in media, actually are not so beneficial. Furthermore, they not only may cause damage to health but also death...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28192582/use-of-electronic-nicotine-delivery-systems-among-adolescents-status-of-the-evidence-and-public-health-recommendations
#14
Aarti D Kamat, Alison L Van Dyke
Although the prevalence of tobacco smoking has been declining in recent years, the use of electronic nicotine delivery systems (ENDS) such as of electronic cigarettes, vaporizers, and hookahs has been steadily rising, especially among adolescents. ENDS are not only advertised to children, but their sale via the Internet has made them easily accessible to youth. In general, children perceive ENDS as safe, or at least safer than smoking traditional combustible tobacco products; however, exposure to nicotine may have deleterious effects on the developing brain...
February 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28167004/e-cigarettes-an-update-on-considerations-for-the-otolaryngologist
#15
REVIEW
Sneh Biyani, Craig S Derkay
PURPOSE: We provide an update in the literature and national regulations regarding electronic cigarettes with special attention to the pediatric population. BACKGROUND: Electronic nicotine delivery systems (ENDS) are handheld battery operated devices that vaporize nicotine-containing liquids for inhalation. Use of these products has dramatically increased over the last several years, particularly among the youth. ENDS are being marketed with advertising techniques and flavors which appeal to the adolescent and young adult population...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28159423/electronic-nicotine-delivery-systems-and-acceptability-of-adult-cigarette-smoking-among-florida-youth-renormalization-of-smoking
#16
Kelvin Choi, Rachel Grana, Debra Bernat
PURPOSE: There is a dearth of research into whether electronic nicotine delivery systems (ENDS) promote acceptance of cigarette smoking. Therefore, we aimed to assess the association between ENDS exposure, acceptance of cigarette smoking, and susceptibility to cigarette smoking. METHODS: Data from the 2014 Florida Youth Tobacco Survey with a state representative sample of middle and high school students (n = 68,928) were analyzed. Own ENDS use, exposure to ENDS advertising, living with ENDS users, acceptance of adult cigarette smoking, demographics, and known predictors of cigarette smoking were assessed...
May 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28157590/delivery-of-nicotine-aerosol-to-mice-via-a-modified-electronic-cigarette-device
#17
Timothy W Lefever, Youn O K Lee, Alexander L Kovach, Melanie A R Silinski, Julie A Marusich, Brian F Thomas, Jenny L Wiley
BACKGROUND: Although both men and women use e-cigarettes, most preclinical nicotine research has focused on its effects in male rodents following injection. The goals of the present study were to develop an effective e-cigarette nicotine delivery system, to compare results to those obtained after subcutaneous (s.c.) injection, and to examine sex differences in the model. METHODS: Hypothermia and locomotor suppression were assessed following aerosol exposure or s...
March 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28151705/biomarkers-of-tobacco-exposure-summary-of-an-fda-sponsored-public-workshop
#18
REVIEW
Cindy M Chang, Selvin H Edwards, Aarthi Arab, Arseima Y Del Valle-Pinero, Ling Yang, Dorothy K Hatsukami
Since 2009, the FDA Center for Tobacco Products (CTP) has had the authority to regulate the manufacturing, distribution, and marketing of tobacco products in order to reduce the death and disease caused by tobacco use. Biomarkers of exposure pertain to actual human exposure to chemicals arising from tobacco use and could play an important role across a number of FDA regulatory activities, including assessing new and modified-risk tobacco products and identifying and evaluating potential product standards. On August 3-4, 2015, FDA/CTP hosted a public workshop focused on biomarkers of exposure with participants from government, industry, academia, and other organizations...
March 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28147209/electronic-nicotine-delivery-systems-and-smoking-cessation-in-arkansas-2014
#19
Uwemedimbuk S Ekanem, Victor M Cardenas, Ruiqi Cen, Wanda Simon, Irene P Chedjieu, Morgan Woodward, Robert R Delongchamp, J Gary Wheeler
OBJECTIVES: As of October 2015, evidence needed to make a recommendation about the use of electronic nicotine delivery systems (ENDS) for smoking cessation was limited. We used the 2014 Arkansas Behavioral Risk Factor Surveillance System with additional state-specific questions to determine the prevalence of ENDS use, the impact of ENDS use on smoking cessation, and beliefs about ENDS use in Arkansas. Our objectives were to determine if (1) ENDS use was associated with lower odds of quitting smoking, (2) ENDS users believed that ENDS use was not harmful to their health, and (3) ENDS users believed that switching to ENDS reduced their tobacco-related health risks...
March 2017: Public Health Reports
https://www.readbyqxmd.com/read/28119498/mobile-marketing-an-emerging-strategy-to-promote-electronic-nicotine-delivery-systems
#20
Jennifer Cantrell, Ollie Ganz, Brittany Emelle, Rakiya Moore, Jessica Rath, Elizabeth C Hair, Donna Vallone
No abstract text is available yet for this article.
January 24, 2017: Tobacco Control
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