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Electronic nicotine delivery system

R J Robinson, E C Hensel, K A Roundtree, A G Difrancesco, J M Nonnemaker, Y O Lee
Results of an observational, descriptive study quantifying topography characteristics of twenty first generation electronic nicotine delivery system users in their natural environment for a one week observation period are presented. The study quantifies inter-participant variation in puffing topography between users and the intra-participant variation for each user observed during one week of use in their natural environment. Puff topography characteristics presented for each user include mean puff duration, flow rate and volume for each participant, along with descriptive statistics of each quantity...
2016: PloS One
Eric Egnot, Kim Jordan, John O Elliott
BACKGROUND: Use of the electronic cigarette for nicotine delivery has increased dramatically in recent years. Information continues to emerge on its role as a smoking cessation aid, but little is known about resident physician use of the device in clinical practice. METHODS: In 2015, an electronic survey was administered to resident physicians in one healthcare system in Columbus, Ohio. The survey included questions about personal smoking exposure, knowledge, beliefs, attitudes about electronic cigarettes and early adoption of electronic cigarettes with patients...
October 3, 2016: Postgraduate Medical Journal
Harold J Farber, Smita Pakhale, Enid R Neptune
An important approach to reduce youth tobacco use is the adoption of regulations to prohibit tobacco product sale to individuals under 21 years of age, termed Tobacco 21. In the United States, close to 90% of current smokers started smoking before the age of 18, and 99% before age 26 years. Earlier age of tobacco use initiation is associated with lower rates of smoking cessation. Increasing minimum age to purchase has been shown to reduce tobacco product use among youth. The critical determinant is likely the loss of social sources of tobacco products...
September 30, 2016: Annals of the American Thoracic Society
Clare Meernik, Felicia N Williams, Bruce A Cairns, Ernest J Grant, Adam O Goldstein
No abstract text is available yet for this article.
2016: BMJ: British Medical Journal
Zhu Zhang, Xiaolong Zheng, Daniel Dajun Zeng, Scott J Leischow
BACKGROUND: Dabbing is an emerging method of marijuana ingestion. However, little is known about dabbing owing to limited surveillance data on dabbing. OBJECTIVE: The aim of the study was to analyze Google search data to assess the scope and breadth of information seeking on dabbing. METHODS: Google Trends data about dabbing and related topics (eg, electronic nicotine delivery system [ENDS], also known as e-cigarettes) in the United States between January 2004 and December 2015 were collected by using relevant search terms such as "dab rig...
2016: Journal of Medical Internet Research
Lucinda J England, Van T Tong, Amber Koblitz, Julia Kish-Doto, Molly M Lynch, Brian G Southwell
The increasing availability of emerging non-combusted tobacco products (snus, dissolvables, and electronic nicotine delivery systems or ENDS) may have implications for pregnant women and women of reproductive age. We conducted 15 focus groups to explore how women perceive emerging non-combusted tobacco products and nicotine replacement therapy (NRT) in general, and during pregnancy. Sessions were held in 2013 in four U.S. cities. Participants were 18-40 years old and were pregnant smokers, pregnant quitters, or smokers planning a pregnancy...
December 2016: Preventive Medicine Reports
Noel J Leigh, Ralph I Lawton, Pamela A Hershberger, Maciej L Goniewicz
BACKGROUND: E-cigarettes or electronic nicotine delivery systems (ENDS) are designed to deliver nicotine-containing aerosol via inhalation. Little is known about the health effects of flavoured ENDS aerosol when inhaled. METHODS: Aerosol from ENDS was generated using a smoking machine. Various types of ENDS devices or a tank system prefilled with liquids of different flavours, nicotine carrier, variable nicotine concentrations and with modified battery output voltage were tested...
September 15, 2016: Tobacco Control
Tory Spindle, Marzena Hiler, Alison Breland, Nareg Karaoghlanian, Alan L Shihadeh, Thomas Eissenberg
INTRODUCTION: Electronic cigarettes (ECIGs) aerosolize a liquid solution often containing nicotine. ECIG nicotine delivery may be influenced by user puffing behaviors ("puff topography"). ECIG puff topography can be recorded using mouthpiece-based computerized systems. The present study sought to examine the extent to which these systems influence ECIG nicotine delivery and other ECIG-associated acute effects under ad libitum use conditions. METHODS: Plasma nicotine concentration, heart rate, and subjective effects were assessed in 29 experienced ECIG users using their preferred ECIG battery and liquid (≥ 12 mg/ml nicotine) in two sessions differing only by the presence of a mouthpiece-based device...
July 11, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
Jennifer L Pearson, Michael S Amato, Xi Wang, Kang Zhao, Sarah Cha, Amy M Cohn, George D Papandonatos, Amanda L Graham
INTRODUCTION: A challenge in Electronic Nicotine Delivery System (ENDS) research is how to refer to these devices in ways that are meaningful to current or potential users. The objectives of this study were to: (1) describe the frequency of ENDS terms in a web-based smoking cessation intervention; and (2) determine whether terms vary by US geographic region and date. METHODS: Data were drawn from public posts between 2008-2015 on and limited to US users...
August 16, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
Chastain Anderson, Andrew Majeste, Jakub Hanus, Shusheng Wang
Cigarette smoking remains one of the leading causes of preventable death worldwide. Vascular cell death and dysfunction is a central or exacerbating component in the majority of cigarette smoking related pathologies. The recent development of the electronic nicotine delivery systems known as e-cigarettes provides an alternative to conventional cigarette smoking; however, the potential vascular health risks of e-cigarette use remain unclear. This study evaluates the effects of e-cigarette aerosol extract (EAE) and conventional cigarette smoke extract (CSE) on human umbilical vein endothelial cells (HUVECs)...
September 9, 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
Natalie Thurtle, Rachelle Abouchedid, John R H Archer, James Ho, Takahiro Yamamoto, Paul I Dargan, David M Wood
INTRODUCTION: Electronic nicotine delivery systems (ENDS, often called e-cigarettes) are nicotine delivery devices that heat nicotine into vapour that is inhaled, a process called 'vaping'. Use eclipsed nicotine-replacement therapy (NRT) in 2014 but ENDS role in smoking cessation remains controversial. Safety has not been proven and there have been reports to US poison centres regarding potential ENDS-related nicotine toxicity. A further concern is use of ENDS to vape recreational drugs, but there is limited data to substantiate this...
September 6, 2016: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
Paul Vanderkam, Rémy Boussageon, Michel Underner, Nicolas Langbourg, Yann Brabant, Philippe Binder, Bernard Freche, Nematollah Jaafari
CONTEXT: Smoking is the first cause of preventable death in France and in the world. Without help, it was shown that 80 % of smokers who try to quit smoking relapse after one month with a low long-term success rate. Smoking reduction can concern smokers who did not want to quit or failed in their attempt to weaning. The final aim is to increase attractiveness of drug therapies by developing new products, such as electronic cigarettes, that can compete cigarette without reproducing its harmful effects...
September 2, 2016: La Presse Médicale
Oliver Knight-West, Christopher Bullen
In this review, we discuss current evidence on electronic cigarettes (ECs), a rapidly evolving class of nicotine delivery system, and their role in managing nicotine addiction, specifically in helping smokers to quit smoking and/or reduce the amount of tobacco they smoke. The current evidence base is limited to three randomized trials (only one compares ECs with nicotine replacement therapy) and a growing number of EC user surveys (n=6), case reports (n=4), and cohort studies (n=8). Collectively, these studies suggest modest cessation efficacy and a few adverse effects, at least with the short-term use...
2016: Substance Abuse and Rehabilitation
Richard Miech, Megan E Patrick, Patrick M O'Malley, Lloyd D Johnston
OBJECTIVE: To examine what substances US youth vape. METHODS: Data come from Monitoring the Future, an annual, nationally representative survey of USA 12th-grade, 10th-grade and 8th-grade students. Respondents reported what substance they vaped the last time they used a vaporiser such as an e-cigarette. RESULTS: Among students who had ever used a vaporiser, 65-66% last used 'just flavouring' in 12th, in 10th and in 8th grade, more than all other responses combined...
August 25, 2016: Tobacco Control
K H Awan
OBJECTIVE: E-cigarettes are becoming popular among youth as safe nicotine delivery systems. Many have expressed concern, however, that e-cigarettes may serve as a gateway to future smoking, given their low perceived risk, or that their use may prevent regular smokers from quitting by maintaining their nicotine addiction. The aim of this study was to assess experimentation with and correlates of e-cigarette use among university students. MATERIAL AND METHODS: A cross-sectional study was carried out among 480 university students from four faculties at a university in Riyadh in August-October 2014...
April 2016: Saudi Dental Journal
Mohammad Abul Kaisar, Shikha Prasad, Tylor Liles, Luca Cucullo
It is well known that tobacco consumption is a leading cause of preventable deaths worldwide and has been linked to major diseases ranging from cancer to chronic obstructive pulmonary disease, atherosclerosis, stroke and a host of neurological/neurodegenerative disorders. In the past decade a number of alternative vaping products have hit the market, rapidly gaining consumers especially among the younger population. Electronic nicotine delivery systems or e-cigarettes have become the sought-after product due to the belief that they are much safer than traditional cigarettes...
July 15, 2016: Toxicology
Ellen Meier, Dorothy K Hatsukami
INTRODUCTION: Cannabis and tobacco are the most widely used substances, and are often used together. The present review examines the toxicant exposure associated with co-use (e.g., carbon monoxide, carcinogens), co-use via electronic nicotine delivery systems (ENDS), and problematic methodological issues present across co-use studies. METHOD: An extensive literature search through PubMed was conducted and studies utilizing human subjects and in vitro methods were included...
September 1, 2016: Drug and Alcohol Dependence
Lilian Calderón-Garcidueñas
Smoking has serious health effects. Cigarettes, including tobacco, marijuana, and electronic nicotine delivery systems are very effective ways to inhale harmful amounts of fine and ultrafine particulate matter. Does size matter? Yes, indeed! The smaller the particle you inhale, the higher the ability to produce reactive oxygen species and to readily access the brain. In this issue of the Journal of Alzheimer's Disease, Durazzo provides evidence of an association between active cigarette tobacco smoking in cognitively-normal elders and increased cerebral oxidative stress, while in actively smoking Alzheimer's disease (AD) patients, the association was also seen with smaller left and total hippocampal volumes...
July 22, 2016: Journal of Alzheimer's Disease: JAD
Elizabeth G Klein, Micah Berman, Natalie Hemmerich, Cristen Carlson, SuSandi Htut, Michael Slater
OBJECTIVES: Electronic nicotine delivery systems (ENDS), or e-cigarettes, are heavily marketed online. The purpose of our study was to perform a systematic identification and evaluation of claims made within ENDS retailer and manufacturer websites, and the legal status of such claims. METHODS: We employed a systematic search protocol with popular search engines using 6 terms: (1) e-cigarettes; (2) e-cigs; (3) e-juice; (4) e-liquid; (5) e-hookah; and (6) vape pen...
July 2016: Tobacco Regulatory Science
Dale Dagar Maglalang, Cati Brown-Johnson, Judith J Prochaska
With attention to the rapidly growing market of electronic nicotine delivery systems (ENDS/e-cigarettes) and the fastest growing US ethnic minority group, the current study explored associations between awareness, perceived risks, and use of ENDS among Asian American and Pacific Islander (AAPI) young adults. AAPI young adults (ages 18-25) in California were recruited via social media, college classes, listservs for AAPI-serving non-profits, and snowball sampling to complete an anonymous survey between 2014 and 2015...
December 2016: Preventive Medicine Reports
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