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https://www.readbyqxmd.com/read/29933369/meditation-or-exercise-for-preventing-acute-respiratory-infection-mepari-2-a-randomized-controlled-trial
#1
Bruce Barrett, Mary S Hayney, Daniel Muller, David Rakel, Roger Brown, Aleksandra E Zgierska, Shari Barlow, Supriya Hayer, Jodi H Barnet, Elisa R Torres, Christopher L Coe
BACKGROUND: Practice of meditation or exercise may enhance health to protect against acute infectious illness. OBJECTIVE: To assess preventive effects of meditation and exercise on acute respiratory infection (ARI) illness. DESIGN: Randomized controlled prevention trial with three parallel groups. SETTING: Madison, Wisconsin, USA. PARTICIPANTS: Community-recruited adults who did not regularly exercise or meditate...
2018: PloS One
https://www.readbyqxmd.com/read/29928955/effects-of-different-durations-of-sustained-inflation-during-cardiopulmonary-resuscitation-on-return-of-spontaneous-circulation-and-hemodynamic-recovery-in-severely-asphyxiated-piglets
#2
J Mustofa, P-Y Cheung, S Patel, T F Lee, M Lu, M P Pasquin, M OʼReilly, G M Schmölzer
OBJECTIVE: We previously demonstrated that sustained inflation (SI) during chest compression (CC) significantly reduces time to return of spontaneous circulation (ROSC) when compared to 3:1 compression:ventilation (C:V) ratio during neonatal resuscitation. However, the optimal length of SI during CC to improve ROSC and hemodynamic recovery in severely asphyxiated piglets is unknown. AIM: To examine if different lengths of SI will improve ROSC and hemodynamic recovery in severely asphyxiated piglets...
June 18, 2018: Resuscitation
https://www.readbyqxmd.com/read/29902384/abrupt-deflation-after-sustained-inflation-causes-lung-injury
#3
Bhushan H Katira, Doreen Engelberts, Gail Otulakowski, Regan E Giesinger, Takeshi Yoshida, Martin Post, Wolfgang M Kuebler, Kim A Connelly, Brian P Kavanagh
RATIONALE: Ventilator management in ARDS focuses on 'setting' parameters and not on ventilator disconnection. OBJECTIVE: To determine if abrupt deflation after sustained inflation causes lung injury. METHODS: Male Sprague-Dawley rats were ventilated (6 mL·kg-1) and randomized to Control (n=6, PEEP 3 cmH2O; 100 min) or Intervention (n=6, PEEP 3 to 11 cmH2O over 70 min; abrupt deflation to zero PEEP; ventilation for 30 mins). Lung function and injury was assessed, scanning electron microscopy performed, and microvascular leak timed by Evans Blue dye (n=4/group at 0, 2, 5, 10 & 20 min post deflation)...
June 14, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29898239/a-novel-balloon-technique-to-induce-intra-abdominal-hypertension-and-its-effects-on-cardiovascular-parameters-in-a-conscious-dog-model
#4
Min Jang, Won-Gyun Son, Sang-Min Jo, Hyunseok Kim, Chi Won Shin, Inhyung Lee
OBJECTIVE: To evaluate a new balloon technique to induce intra-abdominal hypertension (IAH) and abdominal compartment syndrome in a conscious dog model, and to evaluate the effect of intra-abdominal pressure (IAP) on cardiovascular, respiratory, and arterial blood gas values in conscious dogs with IAH. DESIGN: Prospective, experimental study. SETTING: University-based small animal research facility. ANIMALS: Six healthy Beagle dogs, 4 males, and 2 females...
June 13, 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29894017/arrhythmic-outcome-of-arrhythmogenic-right-ventricular-cardiomyopathy-patients-without-implantable-defibrillators
#5
Weijia Wang, Julia Cadrin Tourigny, Aditya Bhonsale, Crystal Tichnell, Brittney Murray, Oliver Monfredi, Jonathan Chrispin, Jane Crosson, Harikrishna Tandri, Cynthia A James, Hugh Calkins
BACKGROUND: Implantable defibrillators (ICD) are an important therapy for arrhythmogenic right ventricular cardiomyopathy (ARVC) patients at high risk of sudden death. Given the high appropriate ICD therapy rate, some have argued that the mere act of implanting an ICD inflates the malignant arrhythmia rate in ARVC. OBJECTIVE: To report the arrhythmic course of ARVC patients without ICDs at the fulfillment of the 2010 Task Force Criteria and explore predictors of malignant ventricular arrhythmias...
June 12, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29800283/longitudinal-associations-of-cigarette-prices-with-smoking-cessation-the-coronary-artery-risk-development-in-young-adults-cardia-study
#6
Stephanie L Mayne, Penny Gordon-Larsen, Pamela J Schreiner, Rachel Widome, David R Jacobs, Kiarri N Kershaw
Introduction: Few studies have used longitudinal cohort data to examine associations of cigarette prices with smoking cessation or whether price sensitivity varies by income or education. This study examines these associations in a multi-center U.S. cohort and explores whether associations vary by education and income. Methods: Longitudinal data from baseline daily cigarette smokers aged 18-30 years old in the Coronary Artery Risk Development in Young Adults (CARDIA) study were linked to inflation-adjusted cigarette carton prices from the Council for Community and Economic Research Cost of Living Index based on residential address at baseline and in years 7, 10, and 15 (1985-2001)...
May 25, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29721261/livelihood-changes-matter-for-the-sustainability-of-ecological-restoration-a-case-analysis-of-the-grain-for-green-program-in-china-s-largest-giant-panda-reserve
#7
Jianying Xu, Qing Wang, Ming Kong
Payments for ecosystem services (PES) are expected to promote ecological restoration while simultaneously improving human livelihoods. As an adaptive management tool, PES programs should be dynamic and adjusted according to changing natural and socio-economic contexts. Taking the implementation of China's famous ecological restoration policy known as the Grain for Green Program (GGP) in the Wolong National Nature Reserve as an example, we analyzed changes in the livelihood capitals and strategies of local households that had participated in the GGP over a 10-year period and discussed the implications of these changes for the next stage of the program's implementation...
April 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29687420/from-agro-industrial-wastes-to-single-cell-oils-a-step-towards-prospective-biorefinery
#8
REVIEW
Batul Diwan, Piyush Parkhey, Pratima Gupta
The reserves of fossil-based fuels, which currently seem sufficient to meet the global demands, is inevitably on the verge of exhaustion. Contemporary raw material for alternate fuel like biodiesel is usually edible plant commodity oils, whose increasing public consumption rate raises the need of finding a non-edible and fungible alternate oil source. In this quest, single cell oils (SCO) from oleaginous yeasts and fungi can provide a sustainable alternate of not only functional but also valuable (polyunsaturated fatty acids (PUFA)-rich) lipids...
April 23, 2018: Folia Microbiologica
https://www.readbyqxmd.com/read/29669283/induction-and-maintenance-of-cx3cr1-intermediate-peripheral-memory-cd8-t-cells-by-persistent-viruses-and-vaccines
#9
Claire Louse Gordon, Lian Ni Lee, Leo Swadling, Claire Hutchings, Madeleine Zinser, Andrew John Highton, Stefania Capone, Antonella Folgori, Eleanor Barnes, Paul Klenerman
The induction and maintenance of T cell memory is critical to the success of vaccines. A recently described subset of memory CD8+ T cells defined by intermediate expression of the chemokine receptor CX3CR1 was shown to have self-renewal, proliferative, and tissue-surveillance properties relevant to vaccine-induced memory. We tracked these cells when memory is sustained at high levels: memory inflation induced by cytomegalovirus (CMV) and adenovirus-vectored vaccines. In mice, both CMV and vaccine-induced inflationary T cells showed sustained high levels of CX3R1int cells exhibiting an effector-memory phenotype, characteristic of inflationary pools, in early memory...
April 17, 2018: Cell Reports
https://www.readbyqxmd.com/read/29664577/the-gradual-rise-of-memory-inflation
#10
REVIEW
Paul Klenerman
Memory inflation, as a term, has been used for 15 years now to describe the longitudinal development of stable, expanded CD8+ T memory pools with a distinct phenotype and functional profile which emerge in specific infection and vaccine settings. These settings have in common the persistence of antigen, especially cytomegalovirus infection but also more recently adenoviral vector vaccination. However, in contrast to chronic infections which lead to "exhaustion" the repeated antigen encounters experienced by CD8+ T cells lead to development of a robust T-cell population structure which maintains functionality and size...
May 2018: Immunological Reviews
https://www.readbyqxmd.com/read/29565774/muscle-hypertrophy-following-blood-flow-restricted-low-force-isometric-electrical-stimulation-in-rat-tibialis-anterior-role-for-muscle-hypoxia
#11
Toshiaki Nakajima, Seiichiro Koide, Tomohiro Yasuda, Takaaki Hasegawa, Tatsuya Yamasoba, Syotaro Obi, Shigeru Toyoda, Fumitaka Nakamura, Teruo Inoue, David C Poole, Yutaka Kano
Low force exercise training with blood flow restriction (BFR) elicits muscle hypertrophy. We investigated the effects of microvascular hypoxia (i.e., low microvascular O2 partial pressures, PmvO2 ) during contractions on hypertrophic signaling, growth response and key muscle adaptations for increasing exercise capacity. Wistar rats were fitted with a cuff placed around the upper thigh and inflated to restrict limb blood flow. Low force isometric contractions (30 Hz) were evoked via electrical stimulation of the tibialis anterior (TA) nerve...
March 22, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29548564/managing-health-expenditure-inflation-under-a-single-payer-system-taiwan-s-national-health-insurance
#12
Winnie C Yip, Yue-Chune Lee, Shu-Ling Tsai, Bradley Chen
As nations strive to achieve and sustain universal health coverage (UHC), they seek answers as to what health system structures are more effective in managing health expenditure inflation. A fundamental macro-level choice a nation has to make is whether to adopt a single- or a multiple-payer health system. Using Taiwan's National Health Insurance (NHI) as a case, this paper examines how a single-payer system manages its health expenditure growth and draws lessons for other countries whose socioeconomic development is similar to Taiwan's...
November 16, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29538107/recommendations-to-sustain-the-academic-mission-ecosystem-at-u-s-medical-schools
#13
Joseph E Kerschner, Jerris R Hedges, Karen Antman, Edward Abraham, Edgar Colón Negrón, J Larry Jameson
Academic medical center (AMC) faculty, administrators, and leaders have the critical tasks of teaching and training the next generation of health care providers and biomedical researchers, as well as generating new knowledge that improves the health of all. In the United States, medical schools and their affiliated hospitals train remarkably high-quality physicians and scientists, and the research conducted at these institutions results in advances in health. To that end, AMCs have become essential engines for driving better health in the United States and the rest of the world; they also have become essential engines driving the economies of their respective communities and regions...
March 13, 2018: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29530973/the-consequences-of-seasonal-fasting-during-the-dormancy-of-tegu-lizards-salvator-merianae-on-their-postprandial-metabolic-response
#14
Rodrigo S B Gavira, Marina R Sartori, Manuel N Gontero-Fourcade, Bruna F Gomes, Augusto S Abe, Denis V Andrade
Tegu lizards ( Salvator merianae ) aestivate for up to 5 months during Brazil's winter, when they retreat to burrows and halt most activities. Dormant tegus reduce their gastrointestinal (GI) mass, which allows a substantial energy economy. This strategy, however, implies that the first post-dormancy digestion would be more costly than subsequent feeding episodes as a result of GI atrophy. To address this, we determined the postprandial metabolic response (SDA) of the first (M1), second (M2) and several (RM) feeding episodes after tegus' dormancy...
April 19, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29522371/ubc-nepal-expedition-imposed-oscillatory-shear-stress-does-not-further-attenuate-flow-mediated-dilation-during-acute-and-sustained-hypoxia
#15
Joshua C Tremblay, Connor A Howe, Philip N Ainslie, Kyra Ellen Pyke
Experimentally-induced oscillatory shear stress (OSS) and hypoxia reduce endothelial function in humans. Acute and sustained hypoxia may cause increases in resting OSS; however, whether this influences endothelial susceptibility to further increases in OSS is unknown. Healthy lowlanders (n=15, 30{plus minus}6 years [mean{plus minus}SD]) participated in three OSS interventions; two at sea level (normoxia and following 20-minutes of normobaric hypoxia [acute hypoxia, 11% O2 ]) and one 5-7 days after a 9-day ascent to 5050m (sustained hypoxia)...
March 9, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29494748/trends-in-medicare-reimbursement-for-orthopedic-procedures-2000-to-2016
#16
Adam E M Eltorai, Wesley M Durand, Jack M Haglin, Lee E Rubin, Arnold-Peter C Weiss, Alan H Daniels
Understanding trends in reimbursement is critical to the financial sustainability of orthopedic practices. Little research has examined physician fee trends over time for orthopedic procedures. This study evaluated trends in Medicare reimbursements for orthopedic surgical procedures. The Medicare Physician Fee Schedule was examined for Current Procedural Terminology code values for the most common orthopedic and nonorthopedic procedures between 2000 and 2016. Prices were adjusted for inflation to 2016-dollar values...
March 1, 2018: Orthopedics
https://www.readbyqxmd.com/read/29414842/chemical-constituents-and-pharmacological-activity-of-agarwood-and-aquilaria-plants
#17
REVIEW
Shuai Wang, Zhangxin Yu, Canhong Wang, Chongming Wu, Peng Guo, Jianhe Wei
Agarwood, a highly precious non-timber fragrant wood of Aquilaria spp. (Thymelaeaceae), has been widely used in traditional medicine, religious rites, and cultural activities. Due to the inflated demanding and depleted natural resources, the yields of agarwood collected from the wild are shrinking, and the price is constantly rising, which restricts agarwood scientific research and wide application. With the sustainable planting and management of agarwood applied, and especially the artificial-inducing methods being used in China and Southeast Asian countries, agarwood yields are increasing, and the price is becoming more reasonable...
February 7, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29409382/distal-placement-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-reboa-to-restore-hemodynamic-stability-in-a-patient-with-proximal-aortic-rupture
#18
Shira Strauss, Paul Engels, John Harlock
PURPOSE: To report unconventional use of the resuscitative endovascular balloon occlusion of the aorta (REBOA) technique to restore hemodynamic stability in a patient who was hemorrhaging from aortic injury proximal to the target zone of occlusion. CASE REPORT: A 72-year-old woman underwent urgent thoracic stent-graft repair of a ruptured 8×8-cm mycotic pseudoaneurysm. Two months later, follow-up imaging revealed that the proximal aortic stent seal zone had degenerated, so a percutaneous procedure was performed 2 months later to preemptively reinforce the segment of stented aorta...
April 2018: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/29348914/exploring-health-insurance-services-in-sudan-from-the-perspectives-of-insurers
#19
Anas Mustafa Ahmed Salim, Fatima Hashim Mahmoud Hamed
Background: It has been 20 years since the introduction of health insurance in Sudan. This study was the first one that explored health insurance services in Sudan from the perspectives of the insurers. Methods: This was a qualitative, exploratory, interview study. The sampling frame was the list of Social Health Insurance and Private Health Insurance institutions in Sudan. Participants were selected from the four Social Health Insurance institutions and from five Private Health Insurance companies...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29286940/sustained-lung-inflation-at-birth-for-preterm-infants-at-risk-of-respiratory-distress-syndrome-the-proper-pressure-and-duration
#20
N Abd El-Fattah, N Nasef, M F Al-Harrass, Mohammed Khashaba
BACKGROUND: Variations exist among the administered pressure and duration of sustained lung inflation (SLI) in the delivery room (DR). We aimed to evaluate the appropriate pressure and duration needed for SLI in preterm infants with respiratory distress syndrome. METHODS: We prospectively randomized 100 preterm (<32 weeks) infants to receive either conventional therapy of continuous positive airway pressure (CPAP) at 5 cm H2O, or four groups of CPAP plus a single maneuver of SLI at four regimens based on administered pressures and durations; P20D20 (Pressure of 20 cm H2O for a duration of 20 seconds), P20D10 (20 cm H2O for 10 seconds), P15D20 (15 cm H2O for 20 seconds), and P15D10 (15 cm H2O for 10 seconds) using a T-piece ventilator...
2017: Journal of Neonatal-perinatal Medicine
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