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https://www.readbyqxmd.com/read/29921567/diagnosis-and-follow-up-of-type-2-diabetes-in-women-with-pcos-a-role-of-ogtt
#1
Marianne Skovsager Andersen, Dorte Glintborg
Polycystic ovary syndrome (PCOS) is common in premenopausal women. The majority of women with PCOS have insulin resistance and the risk of type 2 diabetes mellitus (T2D) is higher in women with PCOS compared to controls. In non-pregnant women with PCOS, glycemic status may be assessed by oral glucose tolerance test (OGTT), fasting plasma glucose (FPG), or HbA1c. OGTT has been reckoned gold standard test for diagnosing T2D, but OGTT is rarely used for diagnostic purpose in other non-pregnant individuals at risk of T2D, apart from PCOS...
June 19, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29917218/comment-on-the-influence-of-palatable-high-energy-diet-in-diet-induced-obesity-pregnant-rats-on-offspring-oxidative-stress-in-liver
#2
V Brunelli, P Perillo, S Milione
No abstract text is available yet for this article.
June 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29915016/pregnancy-weight-gain-before-diagnosis-and-risk-of-preeclampsia-a-population-based-cohort-study-in-nulliparous-women
#3
Jennifer A Hutcheon, Olof Stephansson, Sven Cnattingius, Lisa M Bodnar, Anna-Karin Wikström, Kari Johansson
Weight gain in early pregnancy may influence a woman's risk of developing preeclampsia. However, the consequences of weight gain throughout pregnancy up to the diagnosis of preeclampsia are unknown. The aim of this study was to determine whether pregnancy weight gain before the diagnosis of preeclampsia is associated with increased risks of preeclampsia (overall and by preeclampsia subtype). The study population included nulliparous pregnant women in the Swedish counties of Gotland and Stockholm, 2008 to 2013, stratified by early pregnancy body mass index category...
June 18, 2018: Hypertension
https://www.readbyqxmd.com/read/29914428/a-retrospective-study-of-gestational-weight-gain-in-relation-to-the-institute-of-medicine-s-recommendations-by-maternal-body-mass-index-in-rural-pennsylvania-from-2006-to-2015
#4
Michael L Power, Melisa L Lott, A Dhanya Mackeen, Jessica DiBari, Jay Schulkin
BACKGROUND: In 2009, the Institute of Medicine (IOM) published guidance on gestational weight gain (GWG) modified by maternal pre-pregnancy body mass index (BMI). Estimates indicate that less than half of US pregnant women have GWG within recommendations. This study examined GWG from before (2006-2009) and after (2010-2015) the release of the IOM guidance in a rural, non-Hispanic white population to assess the proportion of women with GWG outside of IOM guidance, whether GWG became more likely to be within IOM guidance after 2010, and identify potential maternal factors associated with GWG outside of recommendations...
June 18, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29907146/are-women-with-history-of-pre-eclampsia-starting-a-new-pregnancy-in-good-nutritional-status-in-south-africa-and-zimbabwe
#5
Gabriela Cormick, Ana Pilar Betrán, Janetta Harbron, Tina Dannemann Purnat, Catherine Parker, David Hall, Armando H Seuc, James M Roberts, José M Belizán, G Justus Hofmeyr
BACKGROUND: Maternal nutritional status before and during pregnancy is an important contributor to pregnancy outcomes and early child health. The aim of this study was to describe the preconceptional nutritional status and dietary intake during pregnancy in high-risk women from South Africa and Zimbabwe. METHODS: This is a prospective observational study, nested to the CAP trial. Anthropometric measurements before and during pregnancy and dietary intake using 24-h recall during pregnancy were assessed...
June 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29895995/importance-of-adopting-bmi-classifications-using-public-health-action-points-to-delineate-obstetric-risk-factors-resulting-in-worsening-obstetric-outcomes-among-asian-population
#6
Muniswaran Ganeshan, Mohamad Adam Bujang, Shahrul Aiman Soelar, Shamala Devi Karalasingam, Harris Suharjono, Ravichandran Jeganathan
Aims: The aim of this study is to compare obstetric outcomes between overweight and class 1 obesity among pregnant women in their first pregnancy based on WHO's BMI cut-offs and the potential public health action points identified by WHO expert consultations specific for high-risk population such as Asians. Methods: This is a retrospective cohort review of data obtained from the Malaysian National Obstetrics and Gynaecology Registry between the year 2010 and year 2012...
June 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29895848/vitamin-a-and-micronutrient-deficiencies-post-bariatric-surgery-aetiology-complications-and-management-in-a-complex-multiparous-pregnancy
#7
Fiona L Mackie, Nicola S Cooper, Louise J Whitticase, Amanda Smith, William L Martin, Sheldon C Cooper
Adequate vitamin A is essential for healthy pregnancy, but high levels may be teratogenic. We present a patient who underwent bariatric surgery, prior to child bearing, and suffered maternal and foetal complications during eleven pregnancies, possibly associated with vitamin A deficiency, amongst multiple micronutrient deficiencies and risk factors including smoking and obesity. Maternal complications included visual disturbance, night blindness and recurrent infections. Recurrent foetal pulmonary hypoplasia and microphthalmia led to foetal and neonatal loss, not previously described in the medical literature...
June 12, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29895806/maternal-serum-and-breast-milk-adiponectin-the-association-with-infant-adiposity-development
#8
Marhazlina Mohamad, See Ling Loy, Poh Ying Lim, Yu Wang, Kah Leng Soo, Hamid Jan Jan Mohamed
The prevalence of childhood obesity is increasing at an alarming rate in Malaysia. Metabolic changes during pregnancy are critical to the development of infant adiposity, due to imbalanced adipokines production. Hence, we aimed to investigate the association of maternal serum and breast milk adipokines with infant adiposity development. The study was conducted from April 2010 until December 2012. A total of 155 healthy pregnant mothers aged 19 to 40 years were recruited during the first and second trimester in Kelantan, Malaysia...
June 12, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29893663/associations-between-obesity-candidate-gene-polymorphisms-fat-mass-and-obesity-associated-fto-melanocortin-4-receptor-mc4r-leptin-lep-and-leptin-receptor-lepr-and-dietary-intake-in-pregnant-women
#9
Maisa C Martins, Janet Trujillo, Ana Amélia Freitas-Vilela, Dayana R Farias, Eliane L Rosado, Cláudio J Struchiner, Gilberto Kac
Genetic variants associated with dietary intake may be important as factors underlying the development of obesity. We investigated the associations between the obesity candidate genes (fat mass and obesity-associated (FTO), melanocortin-4 receptor (MC4R), leptin (LEP) and leptin receptor) and total energy intake and percentage of energy from macronutrients and ultra-processed foods before and during pregnancy. A sample of 149 pregnant women was followed up in a prospective cohort in Rio de Janeiro, Brazil. A FFQ was administered at 5-13 and 30-36 weeks of gestation...
June 12, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29884793/skin-microbiota-in-obese-women-at-risk-for-surgical-site-infection-after-cesarean-delivery
#10
Kara M Rood, Irina A Buhimschi, Joseph A Jurcisek, Taryn L Summerfield, Guomao Zhao, William E Ackerman, Weiwei Wang, R Wolfgang Rumpf, Stephen F Thung, Lauren O Bakaletz, Catalin S Buhimschi
The obesity pandemic in the obstetrical population plus increased frequency of Cesarean delivery (CD) has increased vulnerability to surgical site infection (SSI). Here we characterized the microbiome at the site of skin incision before and after CD. Skin and relevant surgical sites were sampled before and after surgical antisepsis from obese (n = 31) and non-obese (n = 27) pregnant women. We quantified bacterial biomass by qPCR, microbial community composition by 16sRNA sequencing, assigned operational taxonomic units, and stained skin biopsies from incision for bacteria and biofilms...
June 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29884603/individually-tailored-adaptive-intervention-to-manage-gestational-weight-gain-protocol-for-a-randomized-controlled-trial-in-women-with-overweight-and-obesity
#11
Danielle Symons Downs, Jennifer S Savage, Daniel E Rivera, Joshua M Smyth, Barbara J Rolls, Emily E Hohman, Katherine M McNitt, Allen R Kunselman, Christy Stetter, Abigail M Pauley, Krista S Leonard, Penghong Guo
BACKGROUND: High gestational weight gain is a major public health concern as it independently predicts adverse maternal and infant outcomes. Past interventions have had only limited success in effectively managing pregnancy weight gain, especially among women with overweight and obesity. Well-designed interventions are needed that take an individualized approach and target unique barriers to promote healthy weight gain. OBJECTIVE: The primary aim of the study is to describe the study protocol for Healthy Mom Zone, an individually tailored, adaptive intervention for managing weight in pregnant women with overweight and obesity...
June 8, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29882903/the-emerging-role-of-biomarkers-in-the-diagnosis-of-gestational-diabetes-mellitus
#12
REVIEW
Natassia Rodrigo, Sarah J Glastras
Gestational diabetes mellitus (GDM) is a common complication of pregnancy; its rising incidence is a result of increased maternal obesity and older maternal age together with altered diagnostic criteria identifying a greater proportion of pregnant women with GDM. Its consequences are far-reaching, associated with poorer maternal and neonatal outcomes compared to non-GDM pregnancies, and GDM has implications for metabolic health in both mother and offspring. Objective markers to identify women at high risk for the development of GDM are useful to target therapy and potentially prevent its development...
May 23, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29882369/prevalence-and-risk-factors-for-urinary-incontinence-in-pregnancy-in-ikere-ekiti-nigeria
#13
Temitope O Okunola, Olaolu A Olubiyi, Sunday Omoya, Babatunde Rosiji, Kayode O Ajenifuja
AIMS: The objective of this study was to determine the prevalence and associated risk factors for urinary incontinence (UI) among antenatal clinic attendees in a low resourced setting in Nigeria. METHODS: This study was a cross-sectional study involving pregnant women aged 18-45 years. Data was obtained from 442 pregnant women using the English version International Consultation on Incontinence Questionnaire-Urinary Incontinence-Short form (ICIQ-UI-SF) from July 2017-September 2017...
June 8, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29881627/mighty-mums-a-lifestyle-intervention-at-primary-care-level-reduces-gestational-weight-gain-in-women-with-obesity
#14
Karin Haby, Marie Berg, Hanna Gyllensten, Ragnar Hanas, Åsa Premberg
Background: Obesity (BMI ≥30) during pregnancy is becoming an increasing public health issue and is associated with adverse maternal and perinatal outcomes. Excessive gestational weight gain (GWG) further increases the risks of adverse outcomes. However, lifestyle intervention can help pregnant women with obesity to limit their GWG. This study evaluated whether an antenatal lifestyle intervention programme for pregnant women with obesity, with emphasis on nutrition and physical activity, could influence GWG and maternal and perinatal outcomes...
2018: BMC Obesity
https://www.readbyqxmd.com/read/29881626/wrist-worn-optical-and-chest-strap-heart-rate-comparison-in-a-heterogeneous-sample-of-healthy-individuals-and-in-coronary-artery-disease-patients
#15
Francesco Sartor, Jos Gelissen, Ralph van Dinther, David Roovers, Gabriele B Papini, Giuseppe Coppola
Background: The need for unobtrusive HR (heart rate) monitoring has led to the development of a new generation of strapless HR monitors. The aim of this study was to determine whether such an unobtrusive, wrist-worn optical HR monitor (OHRM) could be equivalent and therefore a valid alternative to a traditional chest strap during a broad range of activities in a heterogeneous healthy population and coronary artery disease (CAD) patients. Methods: One hundred ninety-nine healthy volunteers, 84 males and 115 females, including 35 overweight-obese subjects, 53 pregnant women, and 20 CAD patients were tested in the present study...
2018: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29878938/cardiac-structure-and-function-in-morbidly-obese-parturients-an-echocardiographic-study
#16
Bigna S Buddeberg, Nicole L Fernandes, Adri Vorster, Blanche J Cupido, Carl J Lombard, Justiaan L Swanevelder, Thierry Girard, Robert A Dyer
BACKGROUND: The increasing prevalence of obesity worldwide is a major threat to global health. Cardiac structural and functional changes are well documented for obesity as well as for pregnancy, but there is limited literature on morbidly obese parturients. We hypothesized that there are both cardiac structural and functional differences between morbidly obese pregnant women and pregnant women of normal body mass index (BMI). METHODS: This prospective cross-sectional study was performed in 2 referral maternity units in Cape Town, South Africa, over a 3-month period...
June 5, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29875982/internal-hernia-in-pregnant-woman-after-roux-en-y-gastric-bypass-surgery
#17
Bogna Warsza, Blazej Richter
Laparoscopic Roux-en-Y gastric bypass has become the most common obesity surgery procedure worldwide over the last two decades. Many patients undergoing the procedure are women of reproductive age. This carries a risk for developing gastric bypass-related complications during pregnancy. One of the potentially serious risks is an internal hernia. We present a patient in the third trimester of pregnancy with an internal hernia following a laparoscopic Roux-en-Y gastric bypass for morbid obesity. We discuss the importance of computed tomography (CT) in the diagnosis of an internal hernia and review key CT findings including compression of the superior mesenteric vein, which proved to be crucial in diagnosing the internal hernia in this patient...
January 2018: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/29875026/adequacy-of-nutritional-intake-during-pregnancy-in-relation-to-prepregnancy-bmi-results-from-the-3d-cohort-study
#18
Lise Dubois, Maikol Diasparra, Brigitte Bédard, Cynthia K Colapinto, Bénédicte Fontaine-Bisson, Richard E Tremblay, William D Fraser
Our study compares adequacy of nutritional intakes among pregnant women with different prepregnancy BMI and explores associations between nutritional intakes during pregnancy and both prepregnancy BMI and gestational weight gain (GWG). We collected dietary information from a large cohort of pregnant Canadian women (n 861) using a 3-d food record. We estimated usual dietary intakes of energy (E), macronutrients and micronutrients using the National Cancer Institute method. We also performed Pearson's correlations between nutritional intakes and both prepregnancy BMI and GWG...
June 7, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29873682/pregnancy-loss-of-control-over-eating-a-longitudinal-study-of-maternal-and-child-outcomes
#19
Nadia Micali, Haya Al Essimii, Alison E Field, Janet Treasure
Background: To our knowledge, no previous studies have investigated longitudinal outcomes of maternal loss of control over eating (LOC) in pregnancy in a general population sample. Objective: We aimed to determine whether pregnancy LOC is associated with dietary, gestational weight gain, and offspring birth-weight outcomes in a large population-based prospective study of pregnant women and their children. We also explored the association with offspring weight at age 15...
June 5, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29873429/microbiome-in-normal-and-pathological-pregnancies-a-literature-overview
#20
Carla R Taddei, Ramon V Cortez, Rosiane Mattar, Maria Regina Torloni, Silvia Daher
This review summarizes recent findings on the changes that occur during pregnancy in the composition of the vaginal and gut microbiome and their association with metabolic, hormonal, and immunological factors. Despite many studies on the topic, the vaginal and gut microbial profiles and their influence on the course of pregnancy are still unclear. We present data suggesting that, contrary to traditional understanding, the placenta is not sterile but has a microbial community. We review and discuss new findings on changes in the richness and diversity of the microbiota of pregnant women with term or preterm births, obesity, and gestational diabetes mellitus...
June 6, 2018: American Journal of Reproductive Immunology: AJRI
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