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obesity pregnant

Débora Ayres Saraiva, Nathalie Anne de Oliveira E Silva de Morais, Carolina Martins Corcino, Tatiana Martins Benvenuto Louro Berbara, Annie Schtscherbyna, Mischelle Santos, Heron Botelho, Mario Vaisman, Patrícia de Fátima Dos Santos Teixeira
OBJECTIVE: To evaluate iodine status among pregnant women from a coastal state after Brazilian governmental resolution reducing iodine concentrations in table salt. Secondarily, we correlated urinary iodine concentration (UIC) with thyroid volume and hormones. METHODS: Inductively coupled plasma mass spectrometry was used to assess UIC from 629 samples of 244 first trimester pregnant women. Thyroid ultrasound, serum thyroglobulin, thyrotropin, free thyroxine, and antithyroid antibodies were measured as iodine concentrations on samples of table salt from patient's home...
February 14, 2018: Nutrition
Merita Vuniqi-Krasniqi, Myrvete Paçarada, Qëndresë Daka, Zeqir Dervishi, Astrit Bimbashi, Kushtrim Dakaj
Background: Relationships between in-vitro fertilization (IVF), gestational hypertension, and pregnancy outcomes are demonstrated in a number of studies. However, it is still debated if IVF treatment or specific characteristics of infertile patients are responsible for worse obstetrical and neonatal outcomes. Objective: The aim of this study was to investigate maternal characteristics associated with hypertensive disorders (HD) in IVF conceived pregnancies and to assess the obstetrical and neonatal outcomes...
February 2018: International Journal of Reproductive Biomedicine (Yazd, Iran)
Max Mongelli
Although sonographic techniques have vastly improved the clinical estimation of gestational age (GA), the reality remains that in many developing countries pregnant women have no access to ultrasound facilities. Clinicians traditionally relied on the date of the last menstrual period (LMP), or - more recently - measurement of the symphysis-fundus height (SFH). Both of these are known to have limitations. The technique of SFH measurement was first described by Spiegelberg in the German literature in 1891 (Lehrbuch der geburtshulfe fur arzte und studierende...
April 19, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
Anita Zutshi, Jayasree Santhosh, Julie Sheikh, Fareeha Naeem, Ahmed Al-Hamedi, Shahla Khan, Eishthiag Al-Said
Objectives: This study aimed to determine the prevalence of early pregnancy obesity among Omani women and to review maternal antenatal complications, intrapartum and postpartum events and neonatal complications among such women in comparison to women of normal weight. Methods: This retrospective cohort study included 2,652 pregnant Omani women who delivered at the Royal Hospital, Muscat, Oman, between November 2011 and April 2012. The patients' electronic medical records were reviewed for antenatal, intrapartum and postpartum data...
February 2018: Sultan Qaboos University Medical Journal
Jasper Most, Porsha M Vallo, Abby D Altazan, Linda Anne Gilmore, Elizabeth F Sutton, Loren E Cain, Jeffrey H Burton, Corby K Martin, Leanne M Redman
Background: To improve weight management in pregnant women, there is a need to deliver specific, data-based recommendations on energy intake. Objective: This cross-sectional study evaluated the accuracy of an electronic reporting method to measure daily energy intake in pregnant women compared with total daily energy expenditure (TDEE). Methods: Twenty-three obese [mean ± SEM body mass index (kg/m2): 36.9 ± 1.3] pregnant women (aged 28...
April 1, 2018: Journal of Nutrition
Lisa Jahns, Wendy Davis-Shaw, Alice H Lichtenstein, Suzanne P Murphy, Zach Conrad, Forrest Nielsen
Evidence-based dietary guidance in the United States has progressed substantially since its inception >100 y ago. This review describes the historical development and significance of dietary guidance in the United States, including the Dietary Guidelines for Americans (DGAs), and emphasizes the foundations upon which they were developed, the process in the formation of past and current guidelines, and present and future applications. Dietary guidance during the first half of the 20th century was focused primarily on food groups in a healthy diet, food safety, safe food storage, and the role of some minerals and vitamins in the prevention of disease...
March 1, 2018: Advances in Nutrition
Jennifer E Dominguez, Andrew D Krystal, Ashraf S Habib
Among obese pregnant women, 15%-20% have obstructive sleep apnea (OSA) and this prevalence increases along with body mass index and in the presence of other comorbidities. Prepregnancy obesity and pregnancy-related weight gain are certainly risk factors for sleep-disordered breathing in pregnancy, but certain physiologic changes of pregnancy may also increase a woman's risk of developing or worsening OSA. While it has been shown that untreated OSA in postmenopausal women is associated with a range of cardiovascular, pulmonary, and metabolic comorbidities, a body of literature is emerging that suggests OSA may also have serious implications for the health of mothers and fetuses during and after pregnancy...
April 11, 2018: Anesthesia and Analgesia
Lindsey M Russo, Brian W Whitcomb, Sunni L Mumford, Marquis Hawkins, Rose G Radin, Karen C Schliep, Robert M Silver, Neil J Perkins, Keewan Kim, Ukpebo R Omosigho, Daniel L Kuhr, Tiffany L Holland, Lindsey A Sjaarda, Enrique F Schisterman
STUDY QUESTION: Is physical activity (PA) associated with fecundability in women with a history of prior pregnancy loss? SUMMARY ANSWER: Higher fecundability was related to walking among overweight/obese women and to vigorous PA in women overall. WHAT IS KNOWN ALREADY: PA may influence fecundability through altered endocrine function. Studies evaluating this association have primarily utilized Internet-based recruitment and self-report for pregnancy assessment and have yielded conflicting results...
April 10, 2018: Human Reproduction
Drude S Lauridsen, Peter Sandøe, Lotte Holm
BACKGROUND: Pregnant women with a body mass index (BMI) ≥ 30 kg/m2 have been targeted in health-care systems in many western countries as a high-risk group. However, we have limited knowledge of the long-term significance of this prenatal care policy. OBJECTIVE: To investigate accounts women give of their experiences of being targeted as severely overweight during pregnancy when they look back at the intervention 4-5 years later. DESIGN: Interpretive analysis based on 21 semi-structured interviews conducted 4-5 years after the pregnancy with Danish mothers categorized as having a pre-pregnancy BMI ≥ 30...
April 6, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
Hannah Porter, Delia S West, Mario A Cleves, Marie E Saylors, Aline Andres, Rebecca A Krukowski
BACKGROUND: Understanding the role of home food environment on gestational weight gain (GWG) may provide a useful weight management strategy to help reduce excessive GWG. MATERIALS AND METHODS: Pregnant women recruited between 2011 and 2014 (N = 165; normal weight N = 65, overweight N = 62, obese N = 38) in Arkansas completed measures of high-fat food availability, low-fat food availability, and food storage practices at baseline (4-10 weeks) and 30 weeks gestation...
April 5, 2018: Journal of Women's Health
Saqer Althunayyan, Evangelos Karamitosos
Fournier gangrene is a rapidly progressive necrotizing fasciitis of the perianal and genitourinary area. Although typically affects men, we present here a rare disease founding in a pregnant woman. An obese 36-year-old female patient in her third trimester of pregnancy presented with a history of perianal pain and swelling. She was subsequently diagnosed with Fournier gangrene and underwent emergency cesarean section with a surgical debridement. The key to successful outcomes in such a complicated presentation of Fournier gangrene includes a high index of suspicion, fluid resuscitation, rapid administration of broad-spectrum antibiotics, and an early interdisciplinary approach by multiple teams...
April 2018: Saudi Medical Journal
Frankie J Fair, Helen Watson, Rachel Gardner, Hora Soltani
BACKGROUND: The practice of antenatal breast expression (ABE) has been proposed as a strategy to promote successful breastfeeding. Although there has been some focus on the evaluation of the effects of ABE in promotion of breastfeeding, little or no evidence exists on women's experiences of ABE or opinions on ABE, particularly amongst overweight or obese women. METHODS: This study aimed to explore women's knowledge, practices and opinions of ABE, and any differences within the overweight and obese subgroups...
April 4, 2018: Reproductive Health
Eyerahi Bravo-Flores, Ismael Mancilla-Herrera, Salvador Espino Y Sosa, Marco Ortiz-Ramirez, Verónica Flores-Rueda, Francisco Ibargüengoitia-Ochoa, Carlos A Ibañez, Elena Zambrano, Mario Solis-Paredes, Otilia Perichart-Perera, Maribel Sanchez-Martinez, Diana Medina-Bastidas, Enrique Reyes-Muñoz, Guadalupe Estrada-Gutierrez
Obesity is associated with inflammatory changes and accumulation and phenotype polarization of adipose tissue macrophages (ATMs). Obese pregnant women have alterations in adipose tissue composition, but a detailed description of macrophage population is not available. In this study, we characterized macrophage populations in visceral adipose tissue (VAT) from pregnant women with normal, overweight, and obese pregestational weight. Immunophenotyping of macrophages from VAT biopsies was performed by flow cytometry using CD45 and CD14 as markers of hematopoietic and monocyte linage, respectively, while HLA-DR, CD11c, CD163, and CD206 were used as pro- and anti-inflammatory markers...
April 4, 2018: International Journal of Molecular Sciences
Ahmed M Maged, Ali M El-Semary, Heba M Marie, Doaa S Belal, Ayman Hany, Mohammad A Taymour, Eman F Omran, Sahar M Y Elbaradie, Mohamed A Kamal Mohamed
OBJECTIVE: To test the hypothesis that there is a higher rate of unsuccessful induction of labor (IOL) in post-term obese pregnant women compared to non-obese ones. METHODS: In this prospective cohort study, 144 obese (BMI > 30) and 144 non-obese (BMI < 29.9) post-term (> 41 weeks) pregnant women were recruited. IOL was done by misoprostol or amniotomy and oxytocin infusion according to the Bishop score. Comparison of percentage of failed IOL in both groups (primary outcome) was performed by the Chi-test...
April 2, 2018: Archives of Gynecology and Obstetrics
R Buglione-Corbett, K M Deligiannidis, K Leung, N Zhang, M Lee, M C Rosal, T A Moore Simas
Perinatal depression affects 10-20% of women and is associated with poor outcomes for mother and child. Inflammation is associated with depression in non-pregnant adults. Perinatal depression and inflammation in pregnancy are independently associated with morbidities including obesity, gestational diabetes, preeclampsia, and preterm birth. The role of inflammation in perinatal depression has received little attention. We hypothesized an association between self-reported perinatal depressive symptoms and serum inflammatory biomarkers TNF-α, IL-6, IL-1β, and CRP...
March 30, 2018: Archives of Women's Mental Health
Alessandra Berry, Veronica Bellisario, Pamela Panetta, Carla Raggi, Maria C Magnifico, Marzia Arese, Francesca Cirulli
A growing body of evidence suggests the consumption of high-fat diet (HFD) during pregnancy to model maternal obesity and the associated increase in oxidative stress (OS), might act as powerful prenatal stressors, leading to adult stress-related metabolic or behavioral disorders. We hypothesized that administration of antioxidants throughout gestation might counteract the negative effects of prenatal exposure to metabolic challenges (maternal HFD feeding during pregnancy) on the developing fetus. In this study, female C57BL/6J mice were fed HFD for 13 weeks (from 5-weeks of age until delivery) and were exposed to the N-acetyl-cysteine (NAC) antioxidant from 10-weeks of age until right before delivery...
2018: Frontiers in Behavioral Neuroscience
Aser Abrha, Alexander Suvorov
For the majority of lipophilic compounds, adipose tissue is traditionally considered as a storage depot and only rarely as a target organ. Meanwhile, abnormalities in adipose tissue physiology induced by chemical exposure may contribute to the current epidemic of obesity and metabolic diseases. Polybrominated diphenyl ethers (PBDEs) are a group of lipophilic flame retardants found in the majority of human samples in North America. Their ability to alter the physiology of adipose tissue is unknown. We exposed pregnant mice to 0...
March 29, 2018: Toxics
Lydi-Anne Vézina-Im, Theresa A Nicklas, Tom Baranowski
BACKGROUND: Women of childbearing age (18-44 years) present an important group for understanding sleep, but few studies have focused on this population. No study has investigated the associations among sleep, overweight/obesity, and risk of type 2 diabetes among childbearing-age women in the National Health and Nutrition Examination Survey (NHANES). METHODS: Data were from NHANES, 2005-2008. The study population consisted of 18-44 year old women. Pregnant women and those diagnosed with sleep disorders were excluded...
March 27, 2018: Journal of Women's Health
Oded Langer
The obesity and diabetes epidemic is an unintended consequence of economic, social and technological changes. In non-pregnancy, people identified as high risk to develop type 2 diabetes may delay progression by 30 to 70% with lifestyle interventions and pharmacological agents. In pregnancy, lifestyle interventions has been the primary focus to prevent fetal short and long term complications that may evolve into substantial weight gain and gestational diabetes mellitus (GDM). The dilemma for obstetricians is whether diabetes and obesity can be prevented and not simply treated after the fact...
March 22, 2018: American Journal of Obstetrics and Gynecology
Wieteke M Heidema, Joris van Drongelen, Marc E A Spaanderman, Ralph R Scholten
INTRODUCTION: Pre-pregnancy reduced plasma volume increases the risk on subsequent pre-eclamptic pregnancy. Reduced plasma volume is thought to reflect venous reserve capacity, especially when venous vasculature is constricted and sympathetic tone is elevated. As obesity might affect these variables and also relates to pre-eclampsia, increased body weight may underlie these observations. We hypothesized that the relationship between reduced venous reserve and preeclampsia is independent of body mass index (BMI)...
March 25, 2018: Ultrasound in Obstetrics & Gynecology
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