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https://www.readbyqxmd.com/read/29164546/-testing-the-reliability-and-validity-of-the-taiwan-health-related-quality-of-life-for-nausea-and-vomiting-during-pregnancy-scale
#1
Yi-Hua Chung, Shiau-Ting Tsai, Mei-Chun Liu, Fan-Hao Chou
BACKGROUND: Symptom distress related to pregnancy-related nausea and vomiting is known to impact quality of life in pregnant women. However, few reliable and valid assessment tools are available for research use. PURPOSE: To test the reliability and validity of the Taiwan health-related quality of life for nausea and vomiting during pregnancy (NVPQOL) scale. METHODS: A cross-sectional study design was conducted. A convenience sample of 416 pregnant women in their first and second trimesters were recruited from the prenatal clinics of one medical center and one regional teaching hospital in southern Taiwan...
December 2017: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29162956/risk-assessment-at-11-14-week-antenatal-visit-a-tertiary-referral-center-experience-from-south-india
#2
Anusha Vellamkondu, Akhila Vasudeva, Rajeshwari G Bhat, Asha Kamath, Sapna V Amin, Lavanya Rai, Pratap Kumar
Background: Present study carried out in a tertiary referral hospital in South India attempts to determine the predictive value of integrated screening at 11-14-week antenatal visit. Objectives: To determine the detection rate of fetal abnormalities at 11-14 weeks and also to predict the placental dysfunction disorders based on early integrated evaluation. Method: Integrated screening performed on 440 women between 11 and 14 weeks, including detailed maternal history [medical history, bad obstetric history (BOH)], body mass index (BMI), mean arterial pressure (MAP), detailed ultrasound and maternal serum biochemistry as part of combined first-trimester screening for aneuploidy...
December 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29162857/temporal-expression-pattern-of-genes-during-the-period-of-sex-differentiation-in-human-embryonic-gonads
#3
Linn S Mamsen, Emil H Ernst, Rehannah Borup, Agnete Larsen, Rasmus H Olesen, Erik Ernst, Richard A Anderson, Stine G Kristensen, Claus Y Andersen
The precise timing and sequence of changes in expression of key genes and proteins during human sex-differentiation and onset of steroidogenesis was evaluated by whole-genome expression in 67 first trimester human embryonic and fetal ovaries and testis and confirmed by qPCR and immunohistochemistry (IHC). SRY/SOX9 expression initiated in testis around day 40 pc, followed by initiation of AMH and steroidogenic genes required for androgen production at day 53 pc. In ovaries, gene expression of RSPO1, LIN28, FOXL2, WNT2B, and ETV5, were significantly higher than in testis, whereas GLI1 was significantly higher in testis than ovaries...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162475/-thyrotropin-reference-ranges-during-pregnancy-in-the-province-of-huelva-spain
#4
A Ortega Carpio, I Vázquez Rico, M A Castaño López, L Duarte González, M Montilla Álvaro, A Ruiz Reina
OBJECTIVE: The correct diagnosis of hypothyroidism during pregnancy requires knowledge of the local trimester-specific thyrotropin (TSH) reference ranges. When these are not available, the guidelines recommend upper limits of 2.5, 3.0, and 3.0μU/ml for the 1(st), 2(nd), and 3(rd) trimesters, respectively. The aim is to establish the reference range for our local population. MATERIAL AND METHODS: A population-based observational study was performed on healthy pregnant women from 11 healthcare centres in the province of Huelva...
November 18, 2017: Semergen
https://www.readbyqxmd.com/read/29160571/sacral-neuromodulation-and-pregnancy-results-of-a-national-survey-carried-out-for-the-neuro-urology-committee-of-the-french-association-of-urology-afu
#5
Pauline Roulette, Evelyne Castel-Lacanal, Sylvain Sanson, Romain Caremel, Véronique Phé, Stéphane Bart, Franck Duchêne, Marianne De Sèze, Alexia Even, Andréa Manunta, Maria C Scheiber-Nogueira, Pascal Mouracade, Catherine-Marie Loche, Emmanuel Chartier-Kastler, Alain Ruffion, Gilles Karsenty, Xavier Gamé
AIMS: To assess the impact of sacral neuromodulation (SNM) on pregnancy and vice-versa, by identifying women who had received SNM for lower-urinary tract symptoms (LUTS) and had become pregnant. METHODS: A cross-sectional descriptive study was carried out based on responses to an on-line questionnaire sent to practitioners listed on the InterStim enCaptureTM National Registry. Questions were related to pre-pregnancy health and SNM efficacy, deactivation of the device, its impact on LUTS, childbirth, the infant, its reactivation and postpartum effectiveness...
November 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29160421/longitudinal-study-of-lung-function-in-pregnant-women-influence-of-parity-and-smoking
#6
Luciana Duzolina Manfré Pastro, Miriam Lemos, Frederico Leon Arrabal Fernandes, Silvia Regina Dias Médici Saldiva, Sandra Elisabete Vieira, Beatriz Mangueira Saraiva Romanholo, Paulo Hilário Nascimento Saldiva, Rossana Pulcineli Vieira Francisco
OBJECTIVES: To evaluate pulmonary function in the first and third trimesters of pregnancy and analyze the influence of parity and smoking on spirometry parameters. METHODS: This longitudinal prospective study included a cohort of 120 pregnant women. The inclusion criteria were as follows: singleton pregnancy, gestational age less than 13.86 weeks, and no preexisting maternal diseases. The exclusion criteria were as follows: change of address, abortion, and inadequate spirometry testing...
October 2017: Clinics
https://www.readbyqxmd.com/read/29157099/the-association-of-first-trimester-uterine-arteries-doppler-velocimetry-with-different-clinical-phenotypes-of-hypertensive-disorders-of-pregnancy-a-longitudinal-study
#7
Tamara Stampalija, Lorenzo Monasta, Daniela D Di Martino, Mariachiara Quadrifoglio, Leila Lo Bello, Giuseppina D'Ottavio, Sara Zullino, Cristina Mastroianni, Daniela Casati, Valentina Signorelli, Eleonora Rosti, Vera Cecotti, Matteo Ceccarello, Enrico Ferrazzi
INTRODUCTION: Current classification of hypertensive disorders of pregnancy (HDP) is mostly based on temporal classification differentiating HDP according to early and late onset of the disease. However, epidemiological and clinical data suggest that there are two different clinical phenotypes of HDP that coexist at any gestational age: HDP associated to intrauterine growth restriction (HDP-IUGR) and HDP associated to appropriate for gestational age fetal growth (HDP-AGAf). The aim of the study was to evaluate the association of first trimester uterine arteries (UtA) by Doppler velocimetry, and maternal risk factors with HDP according to two different classifications: one based on gestational age at delivery (early- and late-HDP), and one based on longitudinal ultrasound evaluation of fetal growth (HDP-IUGR and HDP-AGAf), independently of the gestational age...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29157043/association-of-first-trimester-maternal-lipid-profiles-and-triglyceride-glucose-index-with-the-risk-of-gestational-diabetes-mellitus-and-large-for-gestational-age-newborn
#8
Azar Pazhohan, Monireh Rezaee Moradali, Nahideh Pazhohan
OBJECTIVE: To evaluate the association of maternal first-trimester plasma lipid profiles, fasting plasma glucose (FPG), and triglyceride (TyG) index with the risk of gestational diabetes mellitus (GDM) and large for gestational age (LGA) infant in Iranian mothers. METHODS: Nine hundred and fifty-four healthy pregnant women were prospectively followed till after delivery. Maternal fasting lipids and glucose concentration were measured at nine-week gestation on average...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29157037/fetal-nuchal-translucency-in-severe-congenital-heart-defects-experiences-in-northern-finland
#9
Julia Alanen, Markku Leskinen, Mikko Sairanen, Teemu Korpimaki, Heikki Kouru, Mika Gissler, Markku Ryynanen, Jaana Nevalainen
OBJECTIVE: To evaluate the performance of first trimester measurement of fetal nuchal translucency (NT) in detection of severe congenital heart defects (CHDs). METHODS: During the study period of 1.1.2008 - 31.12.2011 NT was measured in 31 144 women as a part of voluntary first trimester screening program for Down's syndrome in Northern Finland. NT was measured by personnel trained on the job by experienced staff. No certification or annual audits are required in Finland...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29157031/early-prenatal-vitamin-d-concentrations-and-social-emotional-development-in-infants
#10
Devika Chawla, Bernard Fuemmeler, Sara Benjamin Neelon, Cathrine Hoyo, Susan Murphy, Julie Daniels
BACKGROUND: Many pregnant women in the USA have suboptimal vitamin D, but the impact on infant development is unclear. Moreover, no pregnancy-specific vitamin D recommendations have been widely accepted. AIMS: Given the ubiquitous expression of vitamin D receptors in the brain, we investigated the association between early prenatal plasma 25-hydroxyvitamin D (25(OH)D) concentrations and children's social and emotional development in the Newborn Epigenetic Study, a prospective study of pregnancies from 2009 to 2011 in Durham, North Carolina, United States of America...
November 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29154779/letrozole-pre-treatment-prior-to-medical-termination-of-pregnancy-a-systematic-review
#11
Christopher M Nash, Lauren Philp, Prakesh Shah, Kellie E Murphy
OBJECTIVE(S): The purpose of this systematic review was to evaluate the efficacy of pretreatment with letrozole prior to either a first or second trimester medical termination of pregnancy. STUDY DESIGN: We searched letrozole, femara, aromatase inhibitors, abortifacient agents, termination of pregnancy, and labour induction in MEDLINE, EMBASE, Cochrane Database, Google Scholar, and PubMed from inception of each database until September 2015 with no language limitation...
November 14, 2017: Contraception
https://www.readbyqxmd.com/read/29153738/pregnancy-outcomes-following-cardiac-transplantation
#12
Rohan D'Souza, Elisabeth Soete, Candice K Silversides, Nusrat Zaffar, Tim Van Mieghem, Johan Van Cleemput, Catriona Bhagra, Mathew Sermer, Heather Ross
OBJECTIVE: This study sought to report pregnancy outcomes in women following cardiac transplantation. METHODS: This was a descriptive retrospective cohort study of women with pregnancies following cardiac transplantation managed at two large tertiary centres in Canada and Belgium between 2001 and 2017. RESULTS: Sixteen women had 17 singleton pregnancies following cardiac transplantation. The mean maternal age was 28 ± 5.8, and the transplant-to-pregnancy interval was 7...
November 15, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29153693/up-regulation-of-microrna-202-3p-in-first-trimester-placenta-of-pregnancies-destined-to-develop-severe-preeclampsia-a-pilot-study
#13
Krishna Singh, John Williams, Jordan Brown, Erica T Wang, Bora Lee, Tania L Gonzalez, Jinrui Cui, Mark O Goodarzi, Margareta D Pisarska
MicroRNA (miRNA) expression has not been studied during placentation in pregnancies that develop preeclampsia, when it likely manifests. In this pilot study, miRNA expression in late first trimester placenta from four pregnancies that developed severe preeclampsia matched to controls using the Affymetrix GeneChip® miRNA 3.0 Array identified 9 miRNAs differentially expressed, with miR-202-3p the most significantly overexpressed in severe preeclampsia. Real-time reverse transcription polymerase chain reaction (qRT-PCR) confirmed overexpression of miR-202-3p in a validation cohort, with a 7-fold increase in pregnancies that developed severe preeclampsia (p≤0...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153689/changes-in-echocardiographic-parameters-and-hypertensive-disorders-in-pregnancies-of-women-with-aortic-coarctation
#14
Hiroshi Sato, Chizuko A Kamiya, Masami Sawada, Chinami Horiuchi, Mitsuhiro Tsuritani, Naoko Iwanaga, Hideo Ohuchi, Isao Shiraishi, Hajime Ichikawa, Jun Yoshimatsu
OBJECTIVES: Pregnancy can be well tolerated after the repair of aortic coarctation. However, a higher incidence of hypertensive disorders during these pregnancies was reported. We analyzed the perinatal changes in echocardiographic parameters in women with aortic coarctation and investigated the risk factors of gestational hypertension (GH). METHODS: We retrospectively identified 15 pregnancies in nine Japanese women with aortic coarctation between 1982 and 2015...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153680/associations-between-bacterial-infections-and-blood-pressure-in-pregnancy
#15
Clive J Petry, Ken K Ong, Ieuan A Hughes, Carlo L Acerini, David B Dunger
OBJECTIVES: To test the hypothesis that bacterial infections in pregnancy are related to maternal blood pressure. STUDY DESIGN: Bacterial infection was assessed using antibiotic usage as a surrogate and its association with blood pressure in pregnancy tested in the Cambridge Baby Growth Study. MAIN OUTCOME MEASURES: Antibiotic usage in pregnancy was self-reported in questionnaires. Blood pressure measurements at four time points in pregnancy were collected from the hospital notes of 622 women...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153674/labor-therapeutics-and-bmi-as-risk-factors-for-postpartum-preeclampsia-a-case-control-study
#16
Geraldine Skurnik, Shelley Hurwitz, Thomas F McElrath, Lawrence C Tsen, Stacey Duey, Aditi R Saxena, Ananth Karumanchi, Janet W Rich-Edwards, Ellen W Seely
OBJECTIVES: This study aims at identifying associations between therapeutics used during labor and the occurrence of postpartum preeclampsia (PPPE), a poorly understood entity. STUDY DESIGN AND MAIN OUTCOME MEASURES: This is a case-control study of women who received an ICD-9 code for PPPE (cases) during the years 2009-2011, compared to women with a normotensive term pregnancy, delivery and postpartum period until discharge (controls), matched on age (±1year) and delivery date (±3months)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153670/protocol-for-measurement-of-mean-arterial-pressure-at-10-40weeks-gestation
#17
Llinos Roberts, Piya Chaemsaithong, Daljit S Sahota, Kypros H Nicolaides, Liona C Y Poon
The study aimed to identify the simplest protocol for the measurement of mean arterial pressure (MAP) across 10-40weeks' gestation. 2726 women with uncomplicated singleton pregnancy attending for their routine hospital visit between 10 and 40weeks' gestation were recruited prospectively. The blood pressure (BP) was measured according to the National Heart Foundation of Australia (NHFA) protocol using automated devices. Linearizing regression models were determined for MAP derived from single, repeat and average measurements taken in the left and right arms using the same polynomial power of the best fit model determined using the NHFA protocol...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153665/correlation-between-maternal-body-composition-and-haemodynamic-changes-in-pregnancy-different-profiles-for-different-hypertensive-disorders
#18
I Pisani, G M Tiralongo, D Lo Presti, G Gagliardi, D Farsetti, B Vasapollo, G P Novelli, A Andreoli, H Valensise
OBJECTIVES: To assess and correlate changes in body composition and haemodynamic function during pregnancy. To identify different haemodynamic profiles based on the onset of hypertensive diseases such as gestational hypertension and preeclampsia. METHODS: We enrolled 265 healthy, normotensive pregnant women throughout pregnancy (from 6+0 to 36+0weeks). They were subjected to assessment of body composition and haemodynamic function using non-invasive methods. We divided our population in three groups: group A with physiological pregnancy, group B with gestational hypertension and group C with preeclamptic patients...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153662/comparison-of-three-algorithms-for-prediction-preeclampsia-in-the-first-trimester-of-pregnancy
#19
Rebeca Silveira Rocha, Júlio Augusto Gurgel Alves, Sammya Bezerra Maia E Holanda Moura, Edward Araujo Júnior, Wellington P Martins, Camila Teixeira Moreira Vasconcelos, Fabricio Da Silva Costa, Mônica Oliveira Batista Oriá
OBJECTIVE: To compare a new simple algorithm for preeclampsia (PE) prediction among Brazilian women with two international guidelines - National Institute for Clinical Excellence (NICE) and American College of Obstetricians and Gynecologists (ACOG). METHODS: We performed a secondary analysis of two prospective cohort studies to predict PE between 11 and 13+6weeks of gestation, developed between August 2009 and January 2014. Outcomes measured were total PE, early PE (<34weeks), preterm PE (<37weeks), and term PE (≥37weeks)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153381/prenatal-tvocs-exposure-negatively-influences-postnatal-neurobehavioral-development
#20
Moonhee Chang, Dongheon Lee, Hyesook Park, Mina Ha, Yun-Chul Hong, Yangho Kim, Boong-Nyun Kim, Yeni Kim, Youn-Hee Lim, Eun-Hee Ha
Prenatal exposure to volatile organic compounds may restrict fetal development and adversely influence infants' life. Therefore, we investigated the relationship between prenatal exposure to total volatile organic compounds (TVOC) and postnatal neurobehavioral development. A subsample of 383 pregnant participants was chosen from the prospective birth cohort study of Mother and Children's Environmental Health Study; MOCEH (N=1,751) from three regions of the Republic of Korea (Seoul, Cheon-an, and Ulsan). Participants were enrolled during their first trimester with informed consent...
November 15, 2017: Science of the Total Environment
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