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https://www.readbyqxmd.com/read/29791694/filling-open-screw-holes-in-the-area-of-metaphyseal-comminution-does-not-affect-fatigue-life-of-the-synthes-variable-angle-distal-femoral-locking-plate-in-the-ao-ota-33-a3-fracture-model
#1
Luis Grau, Kevin Collon, Ali Alhandi, David Kaimrajh, Maria Varon, Loren Latta, Fernando Vilella
INTRODUCTION: The aim of this study is to evaluate the biomechanical effect of filling locking variable angle (VA) screw holes at the area of metaphyseal fracture comminution in a Sawbones® (Sawbones USA, Vashon, Washington) model (AO/OTA 33A-3 fracture) using a Synthes VA locking compression plate (LCP) (Depuy Synthes, Warsaw, Indiana). MATERIALS AND METHODS: Seven Sawbones® femur models had a Synthes VA-LCP placed as indicated by the manufacturers technique...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29712566/powiff-prospective-study-of-wrist-internal-fixation-of-fracture-a-protocol-for-a-single-centre-superiority-randomised-controlled-trial-to-study-the-efficacy-of-the-vrp-2-0-distal-radius-plate-austofix-versus-the-va-lcp-depuy-synthes-for-distal-radius-fractures
#2
V D Varghese, Peter Smitham, Stuart Howell, Suzanne Edwards, Mark Rickman
BACKGROUND: Distal radial fractures are one of the most common orthopaedic cases that present to the A&E department. Surgical intervention is warranted in displaced intraarticular fractures and fractures with more than the recommended angulation or shortening, and is most commonly treated with volarly placed fixed angle locking plates. The aim of this study is to determine and compare the efficacy of two different plates for surgical treatment of distal radius fractures. The VRP 2...
April 30, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29692028/-effects-of-light-intensity-on-photosynthetic-capacity-and-light-energy-allocation-in-panax-notoginseng
#3
Xiang Zeng Xu, Jin Yan Zhang, Guang Hui Zhang, Guang Qiang Long, Sheng Chao Yang, Zhong Jian Chen, Fu Gang Wei, Jun Wen Chen
To explore the effects of light intensity on photosynthetic characteristics and light adaptation of the shade-demanding species Panax notoginseng, the responses of photosynthesis to photosynthetic photon flux density, CO2 and sunflecks in the two-year-old Panax notoginseng were investigated under different levels of light intensity (29.8%, 9.6%, 5.0%, 1.4% and 0.2% of full sunlight). Meanwhile, chlorophyll a fluorescence parameter and light energy partitioning were also recorded and calculated in the responsive process...
January 2018: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29678367/a-biomechanical-evaluation-of-different-fixation-strategies-for-posterolateral-fragments-in-tibial-plateau-fractures-and-introduction-of-the-magic-screw
#4
Hui Sun, Qi-Fang He, Bin-Bin Zhang, Yi Zhu, Wei Zhang, Yi-Min Chai
BACKGROUND: Posterior plate fixation is biomechanically the strongest fixation method for posterolateral column fracture (PLCF) of the tibial plateau; however, there are inherent deficiencies and risks of a posterior approach. Thus, the 'magic screw' was proposed to enhance fixation stability of the lateral rafting plate used for PLCF. The purpose of this study was to re-examine and compare the stability of different fixation methods for PLCF. METHODS: Synthetic tibiae models were used to simulate posterolateral split fractures...
April 17, 2018: Knee
https://www.readbyqxmd.com/read/29676089/-study-on-photosynthesis-and-physiological-characteristics-of-acanthopanax-giraldii-on-different-light-intensity
#5
Yu-Feng Chen, Xu-Feng Huang, Rui Gu, Shi-Hong Zhong, Xiao-Dong Wei
This article is aimed to study the response mechanism of Acanthopanax giraldii on different shading intensity to guide its artificial cultivation. The cultivated A. giraldii in Maoxian was used as the research object, set up different shading treatment groups, analyzed photosynthesis, physiology, submicroscopic structure to explore the response mechanism of A. giraldii to different light intensity. Light was the main influencing factor to photosynthetic rate.During morning and afternoon periods,the Pn of the CK group reduced by stomatal limitation and non stomatal limitation factors respectively...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29666996/comparison-of-t2-relaxation-values-in-subtalar-cartilage-between-patients-with-lateral-instability-of-the-ankle-joint-and-healthy-volunteers
#6
Hyun Su Kim, Young Cheol Yoon, Ki Sun Sung, Min-Ji Kim, Soohyun Ahn
PURPOSE: To evaluate the difference between T2 relaxation values of the subtalar cartilage in lateral ankle instability patients and healthy volunteers. MATERIALS AND METHODS: This institutional review board-approved study included 27 preoperative magnetic resonance imaging (MRI) examinations of 26 patients who underwent Broström operations. Data of previously enrolled healthy volunteers (12 volunteers, 13 MRIs) were used as controls. Two radiologists independently measured T2 values in eight posterior subtalar joint cartilage compartments: central calcaneus anterior (CCA) and posterior (CCP), central talus anterior (CTA) and posterior (CTP), lateral calcaneus anterior (LCA) and posterior (LCP), and lateral talus anterior (LTA) and posterior (LTP)...
April 17, 2018: European Radiology
https://www.readbyqxmd.com/read/29664333/relationship-between-tooth-length-and-three-dimensional-mandibular-morphology
#7
Yu Hikita, Tetsutaro Yamaguchi, Daisuke Tomita, Mohamed Adel, Takatoshi Nakawaki, Koshu Katayama, Koutaro Maki, Ryosuke Kimura
OBJECTIVES: To clarify the relationship between tooth length and three-dimensional mandibular morphology in a healthy Japanese population. MATERIALS AND METHODS: This study included 181 Japanese adults: 66 men and 115 women. Cone-beam computed tomography (CBCT) images were acquired with a dentofacial cone-beam x-ray CT scanner. Tooth length was measured with open-source OsiriX medical image processing software. Crown height and root length were measured in the maxillary and mandibular central incisors, lateral incisors, canines, first premolars, second premolars, first molars, and second molars...
April 17, 2018: Angle Orthodontist
https://www.readbyqxmd.com/read/29574531/trauma-discrimination-and-psychological-distress-across-vietnamese-refugees-and-immigrants-a-life-course-perspective
#8
Isok Kim, Mary Keovisai, Wooksoo Kim, Sarah Richards-Desai, Asli C Yalim
Vietnamese Americans are a heterogeneous group with varied migration histories. The life course perspective (LCP) suggests that different migration histories (immigrant vs. refugee) may affect their psychological health. Using Vietnamese refugee (n = 291) and immigrant (n = 211) subsamples from the National Latino and Asian American Study, selected LCP factors relevant to foreign-born Vietnamese were examined for their associations with psychological distress. Two separate regressions were conducted to examine differential factors across the subgroups...
March 24, 2018: Community Mental Health Journal
https://www.readbyqxmd.com/read/29574512/minimally-invasive-plate-osteosynthesis-in-humerus-nonunion-after-intramedullary-nailing
#9
Christian Allende, Fernando Vanoli, Luciano Gentile, Natalia Gutierrez
INTRODUCTION: The purpose of this study was to evaluate the results achieved after the use of lateral minimally invasive plate osteosynthesis (MIPO) in oligotrophic humerus nonunions resulting from failed intramedullary nailing (IM). METHOD: We evaluated nine patients with humerus nonunion after failed locked intramedullary nailing, all treated using 3.5-mm locked compression plates (LCP) placed through lateral minimally invasive approaches, between 2010 and 2016...
March 24, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29551896/targeted-co-delivery-of-beclin-1-sirna-and-fty720-to-hepatocellular-carcinoma-by-calcium-phosphate-nanoparticles-for-enhanced-anticancer-efficacy
#10
Jun-Yi Wu, Zhong-Xia Wang, Guang Zhang, Xian Lu, Guang-Hui Qiang, Wei Hu, An-Lai Ji, Jun-Hua Wu, Chun-Ping Jiang
Purpose: FTY720, known as fingolimod, is a new immunosuppressive agent with effective anticancer properties. Although it was recently confirmed that FTY720 inhibits cancer cell proliferation, FTY720 can also induce protective autophagy and reduce cytotoxicity. Blocking autophagy with Beclin 1 siRNA after treatment with FTY720 promotes apoptosis. The objective of this study was to enhance the anticancer effect of FTY720 in hepatocellular carcinoma (HCC) by targeted co-delivery of FTY720 and Beclin 1 siRNA using calcium phosphate (CaP) nanoparticles (NPs)...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29540439/battery-malfunction-of-a-leadless-cardiac-pacemaker-a-worrisome-single-center-experience
#11
Sergio Richter, Michael Döring, Micaela Ebert, Kerstin Bode, Andreas Müssigbrodt, Philipp Sommer, Daniela Husser, Gerhard Hindricks
Leadless cardiac pacemaker (LCP) therapy has been established clinically as a feasible and safe alternative to conventional transvenous pacemaker therapy for patients with an indication for single-chamber right-ventricular pacing.1-3 However, reports on loss of telemetry and pacing output due to abrupt battery failure called the safety of one of the two commercially available systems seriously into question. The initial battery advisory with the Nanostim™ LCP was issued by the manufacturer in October 2016, who instantly called a global stop to Nanostim™ implants...
March 14, 2018: Circulation
https://www.readbyqxmd.com/read/29530668/cleavage-of-poly-cis-1-4-isoprene-rubber-as-solid-substrate-by-cultures-of-gordonia-polyisoprenivorans
#12
R Andler, S Hiessl, O Yücel, M Tesch, A Steinbüchel
Potential biotechnological recycling processes for rubber products include the bacterial degradation of poly(cis-1,4-isoprene) (IR) in order to achieve its total biodegradation or its biotransformation into useful products. The actinomycete Gordonia polyisoprenivorans strain VH2 catalyzes the degradation of IR and enables its use as a sole carbon source via β-oxidation. The initial cleavage reaction is catalyzed by the extracellular latex clearing protein (Lcp). This dioxygenase is the key enzyme for the formation of oligo(cis-1,4-isoprene) molecules with different lengths, i...
March 9, 2018: New Biotechnology
https://www.readbyqxmd.com/read/29501193/a-general-strategy-to-prepare-sers-active-filter-membranes-for-extraction-and-detection-of-pesticides-in-water
#13
S Fateixa, M Raposo, H I S Nogueira, T Trindade
An important feature in the fabrication of surface-enhanced Raman scattering (SERS) platforms is, together with the high efficiency, to allow the rapid collection and analysis of a vestigial analyte. Conventional substrates based on rigid solid materials or metal hydrosols are not suitable for sample extraction, limiting their application in areas such as water quality monitoring. Herein, we have developed a strategy to fabricate SERS active substrates (Ag/LCP) based on liquid-crystal polymer (LCP) textile fibers decorated with Ag nanoparticles (NPs)...
May 15, 2018: Talanta
https://www.readbyqxmd.com/read/29500450/in-vivo-virulence-of-mycobacterium-tuberculosis-depends-on-a-single-homologue-of-the-lytr-cpsa-psr-proteins
#14
S Malm, S Maaß, U E Schaible, S Ehlers, S Niemann
LytR-cpsA-Psr (LCP) domain containing proteins fulfil important functions in bacterial cell wall synthesis. In Mycobacterium tuberculosis complex (Mtbc) strains, the causative agents of tuberculosis (TB), the genes Rv3484 and Rv3267 encode for LCP proteins which are putatively involved in arabinogalactan transfer to peptidoglycan. To evaluate the significance of Rv3484 for Mtbc virulence, we generated a deletion mutant in the Mtbc strain H37Rv and studied its survival in mice upon aerosol infection. The deletion mutant failed to establish infection demonstrating that Rv3484 is essential for growth in mice...
March 2, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29479920/treatment-of-periprosthetic-femoral-fractures-after-total-hip-arthroplasty-vancouver-type-b
#15
Nikola Bulatović, Miroslav Kezunović, Čedomir Vučetić, Nermin Abdić, Ivan Benčić, Tomislav Čengić
The rate of periprosthetic femoral fractures following total hip replacement has been growing steadily in the last 20 years and ranges from 0.1% to 2.1%. These fractures are mostly related to older patients with the presence of chronic diseases and frequently poor bone quality. The treatment is surgically very complex and demanding, followed by a series of complications. The evaluation in this retrospective study included 23 patients who were medically treated from January 2004 to December 2015 with the mean follow-up of 14...
September 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29471322/whole-body-nitrogen-utilization-and-tissue-protein-and-casein-synthesis-in-lactating-primiparous-sows-fed-low-and-high-protein-diets
#16
Lee-Anne Huber, Marko Rudar, Nathalie L Trottier, John P Cant, Cornelis F M de Lange
Twenty-eight lactating Yorkshire and Yorkshire × Landrace primiparous sows were used to test the hypothesis that feeding a diet with reduced CP concentration and supplemented with crystalline amino acids (CAA) does not decrease milk protein yield and litter growth but improves apparent N utilization for milk protein production. Sows were assigned to 1 of 2 dietary treatments: [1] Control (CON; 16.2% CP; analyzed content) or [2] Low CP with CAA to meet estimated requirements of limiting amino acids (LCP; 12...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29449176/rubber-gloves-biodegradation-by-a-consortium-mixed-culture-and-pure-culture-isolated-from-soil-samples
#17
Chairat Nawong, Kamontam Umsakul, Natthawan Sermwittayawong
An increasing production of natural rubber (NR) products has led to major challenges in waste management. In this study, the degradation of rubber latex gloves in a mineral salt medium (MSM) using a bacterial consortium, a mixed culture of the selected bacteria and a pure culture were studied. The highest 18% weight loss of the rubber gloves were detected after incubated with the mixed culture. The increased viable cell counts over incubation time indicated that cells used rubber gloves as sole carbon source leading to the degradation of the polymer...
February 3, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29437587/new-insights-into-the-biomechanics-of-legg-calv%C3%A3-perthes-disease-the-role-of-epiphyseal-skeletal-immaturity-in-vascular-obstruction
#18
M Pinheiro, C A Dobson, D Perry, M J Fagan
OBJECTIVES: Legg-Calvé-Perthes' disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old. The factors that lead to the onset of LCP are still unclear; however, it is believed that interruption of the blood supply to the developing epiphysis is an important factor in the development of the condition. METHODS: Finite element analysis modelling of the blood supply to the juvenile epiphysis was investigated to understand under which circumstances the blood vessels supplying the femoral epiphysis could become obstructed...
February 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29436549/enhanced-delivery-of-sirna-to-triple-negative-breast-cancer-cells-in-vitro-and-in-vivo-through-functionalizing-lipid-coated-calcium-phosphate-nanoparticles-with-dual-target-ligands
#19
Jie Tang, Christopher B Howard, Stephen M Mahler, Kristofer J Thurecht, Leaf Huang, Zhi Ping Xu
The conjugation of ligands to nanoparticle platforms for the target delivery of therapeutic agents to the tumor tissue is one of the promising anti-cancer strategies. However, conventional nanoparticle platforms are not so effective in terms of the selectivity and transfection efficiency. In this study, we designed and developed a dual-target drug/gene delivery system based on lipid-coated calcium phosphate (LCP) nanoparticles (NPs) for significantly enhanced siRNA cellular uptake and transfection efficiency...
March 1, 2018: Nanoscale
https://www.readbyqxmd.com/read/29432319/are-variable-angle-locking-screws-stable-enough-to-prevent-calcaneal-articular-surface-collapse-a-biomechanical-study
#20
Martin C Jordan, Konrad Fuchs, Timo M Heintel, Hendrik Jansen, Stefanie Hoelscher-Doht, Rainer H Meffert
PURPOSE: To compare fixed- or variable-angle locking screws in calcaneal fracture plates using a sawbones biomechanical model. METHODS: Intra-articular calcaneal fractures were created in synthetic bones. Reduction and stabilization was performed with three different plates. In Group A, a fixed-angle locking plate was used with screws fastened perpendicularly to the plate (3.5 LCP, DePuySynthes). In Groups B and C (2.7 VA-LCP, DePuySynthes and 3.5 Aptus, Medartis, respectively), fracture fixation was performed using variable-angle locking plates...
February 9, 2018: Journal of Orthopaedic Trauma
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