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Electronic nicotine delivery devices

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https://www.readbyqxmd.com/read/29122804/the-messages-presented-in-online-electronic-cigarette-promotions-and-discussions-a-scoping-review-protocol
#1
Kahlia McCausland, Bruce Maycock, Jonine Jancey
INTRODUCTION: Electronic cigarettes have become increasingly popular over the last 10 years. These devices represent a new paradigm for tobacco control offering smokers an opportunity to inhale nicotine without inhaling tobacco smoke. To date there are no definite conclusions regarding the safety and long-term health effects of electronic cigarettes; however, there is evidence that they are being marketed online as a healthier alternative to traditional cigarettes. This scoping review aims to identify and describe the breadth of messages (eg, health, smoking-cessation and price related claims) presented in online electronic cigarette promotions and discussions...
November 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/29097588/the-impact-of-flavour-device-type-and-warning-messages-on-youth-preferences-for-electronic-nicotine-delivery-systems-evidence-from-an-online-discrete-choice-experiment
#2
Ce Shang, Jidong Huang, Frank J Chaloupka, Sherry L Emery
OBJECTIVE: To examine the impact of flavour, device type and health warning messages on youth preference for electronic nicotine delivery systems (ENDS), and to provide evidence and data to inform the Food and Drug Administration's potential regulatory actions on ENDS. DESIGN: An online discrete choice experiment was conducted in September 2015. Each participant was given nine choice sets and asked to choose one out of two alternative ENDS products, with varying characteristics in three attributes (flavour, device type and warning message)...
November 2, 2017: Tobacco Control
https://www.readbyqxmd.com/read/29059443/availability-and-placement-of-electronic-nicotine-delivery-systems-at-the-point-of-sale
#3
Kimberly G Wagoner, Eunyoung Song, Jessica King, Kathleen L Egan, Beata Debinski, Mark Wolfson, John Spangler, Erin L Sutfin
Introduction: Electronic nicotine delivery systems (ENDS) are widely available and come in a variety of forms, including disposable cigalikes and refillable tank systems. However, little is known about their placement at the point-of-sale. We explored the placement of various ENDS types among tobacco retailers. Methods: Systematic assessments at the point-of-sale were completed by trained data collectors in 90 tobacco retailers, including grocery stores, convenience stores, and pharmacies in North Carolina, U...
September 9, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29048187/electronic-cigarette-user-plasma-nicotine-concentration-puff-topography-heart-rate-and-subjective-effects-influence-of-liquid-nicotine-concentration-and-user-experience
#4
Marzena Hiler, Alison Breland, Tory Spindle, Sarah Maloney, Thokozeni Lipato, Nareg Karaoghlanian, Alan Shihadeh, Alexa Lopez, Carolina Ramôa, Thomas Eissenberg
Electronic cigarette (ECIG) nicotine delivery and other effects may depend on liquid nicotine concentration and user experience. This study is the first to systematically examine the influence of ECIG liquid nicotine concentration and user experience on nicotine delivery, heart rate, puff topography, and subjective effects. Thirty-three ECIG-experienced individuals and 31 ECIG-naïve cigarette smokers completed 4 laboratory conditions consisting of 2, 10-puff bouts (30-sec interpuff interval) with a 3.3-V ECIG battery attached to a 1...
October 2017: Experimental and Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28884423/electronic-cigarette-use-in-us-adults-at-risk-for-or-with-copd-analysis-from-two-observational-cohorts
#5
Russell P Bowler, Nadia N Hansel, Sean Jacobson, R Graham Barr, Barry J Make, MeiLan K Han, Wanda K O'Neal, Elizabeth C Oelsner, Richard Casaburi, Igor Barjaktarevic, Chris Cooper, Marilyn Foreman, Robert A Wise, Dawn L DeMeo, Edwin K Silverman, William Bailey, Kathleen F Harrington, Prescott G Woodruff, M Bradley Drummond
BACKGROUND: Electronic cigarettes (e-cigarettes) are battery-operated nicotine-delivery devices used by some smokers as a cessation tool as well as by never smokers. OBJECTIVE: To determine the usage of e-cigarettes in older adults at risk for or with chronic obstructive pulmonary disease (COPD). DESIGN: Prospective cohorts. PARTICIPANTS: COPDGene (N = 3536) and SPIROMICS (N = 1060) subjects who were current or former smokers aged 45-80...
September 7, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28819633/clinical-laboratory-evaluation-of-electronic-cigarettes-electronic-nicotine-delivery-systems-methodological-challenges
#6
Melissa D Blank, Alison B Breland, Caroline O Cobb, Tory Spindle, Carolina Ramôa, Thomas Eissenberg
OBJECTIVE: Evaluating electronic cigarettes (ECIGs) in the clinical laboratory is critical to understanding their effects. However, laboratory evaluation of ECIGs can be challenging, as they are a novel, varied, and evolving class of products. The objective of this paper is to describe some methodological challenges to the clinical laboratory evaluation of ECIGs. METHODS: The authors gathered information about challenges involved in the laboratory evaluation of ECIGs...
October 2016: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/28678400/nicotine-vapor-method-to-induce-nicotine-dependence-in-rodents
#7
Marsida Kallupi, Olivier George
Nicotine, the main addictive component of tobacco, induces potentiation of brain stimulation reward, increases locomotor activity, and induces conditioned place preference. Nicotine cessation produces a withdrawal syndrome that can be relieved by nicotine replacement therapy. In the last decade, the market for electronic cigarettes has flourished, especially among adolescents. The nicotine vaporizer or electronic nicotine delivery system is a battery-operated device that allows the user to simulate the experience of tobacco smoking without inhaling smoke...
July 5, 2017: Current Protocols in Neuroscience
https://www.readbyqxmd.com/read/28640563/-smoking-vaping-and-cardiovascular-risk-an-update
#8
Sofia Dalkou, Carole Clair
It is well known that tobacco smoking increases cardiovascular (CV) mortality and morbidity, however, smoking cessation is often neglected compared to other CV risk factors. Behavioral counseling as well as smoking cessation treatments are efficient and do not increase the risk of CV events when used for a defined duration. Electronic nicotine delivery systems (ENDS) contain potentially cardiotoxic substances but in lower concentrations than in cigarettes. The CV effect of ENDS is to date difficult to assess and depends on the type of device used and its mode of consumption...
June 7, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28640562/-vaping-electronic-cigarette-how-to-advise-smokers-in-2017
#9
Isabelle Jacot Sadowski, Jean-Paul Humair, Jacques Cornuz
Questions about electronic cigarettes, also called electronic nicotine delivery systems (ENDS), are very common when advising patients to stop smoking in medical practice. It is widely recognized that the risks of vaping are significantly lower than those of smoking, although there are uncertainties about its long-term health effects. Some studies suggest that vaping helps to stop smoking. Effective smoking cessation medications should be recommended in first line but vaping should not be discouraged when patients choose to use this device, as the main aim is smoking cessation...
June 7, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/28621763/why-don-t-more-smokers-switch-to-using-e-cigarettes-the-views-of-confirmed-smokers
#10
Neil McKeganey, Tiffany Dickson
Whilst e-cigarettes have been characterised by Public Health England as being around 95% less harmful than combustible tobacco products, only a minority of current smokers (around 16% within the UK) are using these devices. In this paper we report the results of an online survey of 650 smokers in contact with a smokers' rights group in the UK. A total of 91% of the smokers surveyed were smoking on a daily basis. Fifty nine percent reported having used electronic nicotine delivery systems, the majority of whom reported having used e-cigarettes...
June 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28572636/nicotine-delivery-from-the-refill-liquid-to-the-aerosol-via-high-power-e-cigarette-device
#11
Nathalie Prévôt, Fabien de Oliveira, Sophie Perinel-Ragey, Thierry Basset, Jean-Michel Vergnon, Jérémie Pourchez
To offer an enhanced and well-controlled nicotine delivery from the refill liquid to the aerosol is a key point to adequately satisfy nicotine cravings using electronic nicotine delivery systems (ENDS). A recent high-power ENDS, exhibiting higher aerosol nicotine delivery than older technologies, was used. The particle size distribution was measured using a cascade impactor. The effects of the refill liquid composition on the nicotine content of each size-fraction in the submicron range were investigated. Nicotine was quantified by liquid chromatography coupled with tandem mass spectrometry...
June 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28483810/evidentiary-support-in-public-comments-to-the-fda-s-center-for-tobacco-products
#12
Natalie Hemmerich, Elizabeth G Klein, Micah Berman
Electronic Nicotine Delivery Systems (ENDS) were introduced into the US market in 2007, and until recently these devices were unregulated at the federal level. In 2014, the US Food and Drug Administration (FDA) published a Notice of Proposed Rulemaking asserting its intention to regulate ENDS and requesting public comments on numerous related issues, including potential limits on the sale of flavored ENDS. This article analyzes key comments submitted to the FDA on the issue of flavor regulation in ENDS and examines the weight and credibility of the evidence presented by both supporters and opponents of regulation...
August 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28482017/evaluation-of-nicotine-pharmacokinetics-and-subjective-effects-following-use-of-a-novel-nicotine-delivery-system
#13
Axel Teichert, Patrick Brossard, Loyse Felber Medlin, Larissa Sandalic, Mikael Franzon, Chris Wynne, Murray Laugesen, Frank Lüdicke
Introduction: Novel nicotine delivery systems represent an evolving part of the tobacco harm reduction strategy. The pharmacokinetic (PK) profile of nicotine delivered by P3L, a pulmonary nicotine delivery system, and its effects on smoking urges and craving relief in relation to Nicorette® inhalator were evaluated. Methods: This open-label, ascending nicotine levels study was conducted in 16 healthy smokers. Three different nicotine delivery levels, 50, 80, and 150 µg/puff delivered by the P3L system were evaluated consecutively on different days, after the use of the Nicorette® inhalator...
May 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28339800/the-dark-cloud-of-recreational-drugs-and-vaping
#14
M S Blundell, P I Dargan, D M Wood
Electronic cigarettes (e-cigarettes) are increasing in popularity with 19% of UK smokers reporting to have used them. The ability to regulate the evaporation temperature in newer electronic nicotine delivery systems (ENDS) facilitates the potential for use of these devices to 'vape' cannabis, novel psychoactive substances (NPS) and other recreational drugs. Vaping cannabis does have the potential to reduce tobacco use and combustible cannabis/tobacco-related disease, but with over one-third of UK adults reporting life-time use of recreational drugs and increasing e-cigarette uptake in adolescent groups the misuse of these devices poses a serious potential public health risk...
March 9, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28270392/qualitative-analysis-of-young-adult-ends-users-expectations-and-experiences
#15
Janet Hoek, Johannes Thrul, Pamela Ling
OBJECTIVES: Despite extensive research into the determinants of electronic nicotine delivery system (ENDS) uptake, few studies have examined the psychosocial benefits ENDS users seek and experience. Using a consumer ritual framework, we explored how ENDS users recreated or replaced smoking practices, and considered implications for smoking cessation. DESIGN: In-depth interviews; data analysed using thematic analysis. SETTING: Dunedin, New Zealand...
March 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28167004/e-cigarettes-an-update-on-considerations-for-the-otolaryngologist
#16
REVIEW
Sneh Biyani, Craig S Derkay
PURPOSE: We provide an update in the literature and national regulations regarding electronic cigarettes with special attention to the pediatric population. BACKGROUND: Electronic nicotine delivery systems (ENDS) are handheld battery operated devices that vaporize nicotine-containing liquids for inhalation. Use of these products has dramatically increased over the last several years, particularly among the youth. ENDS are being marketed with advertising techniques and flavors which appeal to the adolescent and young adult population...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28157590/delivery-of-nicotine-aerosol-to-mice-via-a-modified-electronic-cigarette-device
#17
Timothy W Lefever, Youn O K Lee, Alexander L Kovach, Melanie A R Silinski, Julie A Marusich, Brian F Thomas, Jenny L Wiley
BACKGROUND: Although both men and women use e-cigarettes, most preclinical nicotine research has focused on its effects in male rodents following injection. The goals of the present study were to develop an effective e-cigarette nicotine delivery system, to compare results to those obtained after subcutaneous (s.c.) injection, and to examine sex differences in the model. METHODS: Hypothermia and locomotor suppression were assessed following aerosol exposure or s...
March 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28062365/assessment-of-new-generation-high-power-electronic-nicotine-delivery-system-as-thermal-aerosol-generation-device-for-inhaled-bronchodilators
#18
Jérémie Pourchez, Fabien de Oliveira, Sophie Perinel-Ragey, Thierry Basset, Jean-Michel Vergnon, Nathalie Prévôt
PURPOSE: A need remains for alternative devices for aerosol drug delivery that are low cost, convenient and easy to use for the patient, but also capable of producing small-sized aerosol particles. This study investigated the potential of recent high power electronic nicotine delivery systems (ENDS) as aerosol generation devices for inhaled bronchodilators. METHODS: The particle size distribution was measured using a cascade impactor. The delivery of terbutaline sulfate, a current bronchodilator used for asthma or COPD therapy by inhalation, was studied...
February 25, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28059903/tobacco-e-cigarettes-and-child-health
#19
Lisa A Peterson, Stephen S Hecht
PURPOSE OF THE REVIEW: The availability of the Children's Health Exposure Assessment Resource funded by the National Institute of Environmental Health Sciences provides new opportunities for exploring the role of tobacco smoke exposure in causing harm to children. RECENT FINDINGS: Children of smokers are exposed to nicotine and other harmful tobacco smoke chemicals in utero as well as in their environment. This passive exposure to tobacco smoke has a variety of negative effects on children...
April 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28025560/use-of-electronic-nicotine-delivery-systems-among-adults-with-mental-health-conditions-2015
#20
Claire Adams Spears, Dina M Jones, Scott R Weaver, Terry F Pechacek, Michael P Eriksen
Adults with mental health conditions (MHC) are especially likely to smoke and experience tobacco-related health disparities. Individuals with MHC may also use electronic nicotine delivery devices (ENDS) at disproportionately high rates. However, there is a relative dearth of knowledge regarding ENDS use among individuals with MHC. In a large representative sample of U.S. adults (n = 6051), associations between self-reported MHC diagnoses and ENDS use and susceptibility were examined, stratified by smoking status...
December 23, 2016: International Journal of Environmental Research and Public Health
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