Sherrie L Aspinall, Xinhua Zhao, Chester B Good, Roslyn A Stone, Joy Boresi, Sarah Cox, Chad Bartholomew, David Jansen, Sarah Guterman, Mauricio Patino, Giselle Rivera-Miranda, Mark Burlingame, Justin Frazer, Janelle Sellers, Valerie Stanard Steele, Lauri Witt, Francesca E Cunningham
OBJECTIVES: The objectives of this study were to describe changes in glyburide prescribing in cohorts that were and were not targeted by a risk reduction project, assess factors associated with glyburide discontinuation, and evaluate changes in glycated hemoglobin (ie, HbA(1c)) levels and rates of serious hypoglycemia. METHODS: This historical cohort study included a targeted cohort of 4368 outpatient veterans aged ≥65 years with active prescriptions for glyburide between April 1, 2007 and June 30, 2007 and serum creatinine (SCr) ≥2 mg/dL and a nontargeted cohort of 1886 outpatients meeting these same criteria between July 1, 2007 and September 3, 2007...
February 2011: American Journal of Geriatric Pharmacotherapy