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Global initiative for obstructive lung disease

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https://www.readbyqxmd.com/read/28494181/characterization-of-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome-a-qualitative-analysis
#1
Claudie Rodrigue, Marie-France Beauchesne, Valérie Mallette, Catherine Lemière, Pierre Larivée, Lucie Blais
Approximately 15-20% of patients with chronic obstructive pulmonary disease (COPD) also display characteristics of asthma. In May 2014, the asthma-COPD overlap syndrome (ACOS) was briefly addressed in the Global Initiative for Asthma (GINA) and Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy documents. We evaluated how pulmonologists diagnose and treat ACOS and how they assess its control. Pulmonologists from two university healthcare centers, having ≥ 1 year experience, treating patients with asthma, COPD, or ACOS, were invited to participate in focus groups...
May 11, 2017: COPD
https://www.readbyqxmd.com/read/28490870/pre-and-post-bronchodilator-airway-obstruction-are-associated-with-similar-clinical-characteristics-but-different-prognosis-report-from-a-population-based-study
#2
Sami Sawalha, Linnea Hedman, Eva Rönmark, Bo Lundbäck, Anne Lindberg
INTRODUCTION: According to guidelines, the diagnosis of COPD should be confirmed by post-bronchodilator (post-BD) airway obstruction on spirometry; however, in clinical practice, this is not always performed. The aim of this population-based study was to compare clinical characteristics and prognosis, assessed as mortality, between subjects with airway obstruction divided into pre- but not post-BD obstruction, post-BD airway obstruction (COPD), and subjects without airway obstruction...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28483402/doxycycline-for-outpatient-treated-acute-exacerbations-of-copd-a-randomised-double-blind-placebo-controlled-trial
#3
Patricia van Velzen, Gerben Ter Riet, Paul Bresser, Jeroen J Baars, Bob T J van den Berg, Jan W K van den Berg, Paul Brinkman, Jennece W F Dagelet, Johannes M A Daniels, Dewi R G L Groeneveld-Tjiong, René E Jonkers, Coen van Kan, Frans H Krouwels, Karin Pool, Arjan Rudolphus, Peter J Sterk, Jan M Prins
BACKGROUND: Antibiotics do not reduce mortality or short-term treatment non-response in patients receiving treatment for acute exacerbations of COPD in an outpatient setting. However, the long-term effects of antibiotics are unknown. The aim of this study was to investigate if the antibiotic doxycycline added to the oral corticosteroid prednisolone prolongs time to next exacerbation in patients with COPD receiving treatment for an exacerbation in the outpatient setting. METHODS: In this randomised double-blind placebo-controlled trial, we recruited a cohort of patients with COPD from outpatient clinics of nine teaching hospitals and three primary care centres in the Netherlands...
May 5, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28468060/-associations-between-airflow-obstruction-and-the-risks-of-morbidity-on-major-chronic-diseases-in-chinese-adults-a-prospective-cohort-study
#4
J C Li, F L Lan, C Q Yu, J Lyu, Y Guo, Z Bian, Y L Tan, P Pei, J S Chen, Z M Chen, L M Li
Objective: To examine the prospective associations between airflow obstruction (AFO) and risks of major chronic diseases morbidity in Chinese adults. Methods: Samples of this study were from the China Kadoorie Biobank. A total of 486 996 participants aged 30 to 79 years (mean 51.5 years) at the baseline study, were included after excluding those who self-reported of having heart disease, stroke and cancer at baseline. AFO was defined under the Global Initiative on Obstructive Lung Disease (GOLD) criteria and forced expiratory volume per one second in percentage of the expected one (FEV(1)% P)...
April 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28460847/radiographic-evidence-of-sinonasal-inflammation-in-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome-an-underrecognized-association
#5
Satoshi Hamada, Shuji Tatsumi, Yoshiki Kobayashi, Hisako Matsumoto, Hirotaka Yasuba
BACKGROUND: Sinonasal inflammation on both clinical examinations and imaging significantly impacts both asthma and chronic obstructive pulmonary disease (COPD). OBJECTIVE: The objective of this study was to examine the association between sinonasal inflammation and asthma-COPD overlap syndrome (ACOS). METHODS: A total of 112 patients with a ratio of forced expiratory volume in 1 s to forced vital capacity of less than 70% were enrolled. COPD, asthma, and ACOS were clinically diagnosed according to the 2014 Global Initiative for Asthma and Global Initiative for Chronic Obstructive Lung Disease guidelines...
April 28, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28458527/self-reported-daily-walking-time-in-copd-relationship-with-relevant-clinical-and-functional-characteristics
#6
Maria A Ramon, Cristina Esquinas, Miriam Barrecheguren, Eulogio Pleguezuelos, Jesús Molina, José A Quintano, Miguel Roman-Rodríguez, Karlos Naberan, Carl Llor, Carlos Roncero, Marc Miravitlles
BACKGROUND: Quantifying physical activity in chronic obstructive pulmonary disease (COPD) is important as physical inactivity is related to poor health outcomes. This study analyzed the relationship between patients' self-reported daily walking time and relevant characteristics related to COPD severity. METHODS: Pooled analysis was performed on data from four observational studies on which daily walking time was gathered from a personal interview. Patients were classified as physically inactive if walking time was <30 min/day...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28435245/long-term-effects-of-beta-blocker-use-on-lung-function-in-japanese-patients-with-chronic-obstructive-pulmonary-disease
#7
Naohiro Oda, Nobuaki Miyahara, Hirohisa Ichikawa, Yasushi Tanimoto, Kazuhiro Kajimoto, Makoto Sakugawa, Haruyuki Kawai, Akihiko Taniguchi, Daisuke Morichika, Mitsune Tanimoto, Arihiko Kanehiro, Katsuyuki Kiura
BACKGROUND: Some recent studies have suggested that beta-blocker use in patients with chronic obstructive pulmonary disease (COPD) is associated with a reduction in the frequency of acute exacerbations. However, the long-term effects of beta-blocker use on lung function of COPD patients have hardly been evaluated. PATIENTS AND METHODS: We retrospectively reviewed 31 Japanese COPD patients taking beta-blockers for >1 year and 72 patients not taking them. The association between beta-blocker use and the annual change in forced expiratory volume in 1 second (FEV1) was assessed...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28410285/comorbidities-in-patients-with-chronic-obstructive-pulmonary-disease-and-pulmonary-rehabilitation-outcomes
#8
Pichapong Tunsupon, Ashima Lal, Mohammed Abo Khamis, M Jeffery Mador
PURPOSE: The objective of this study was to evaluate the impact of comorbidities as potential predictors of the response to pulmonary rehabilitation in patients with chronic obstructive pulmonary disease (COPD). METHODS: The study included 165 patients with COPD with exercise limitations. Comorbidity was classified as cardiac, metabolic, orthopedic, behavioral health problems, or other diseases. Number of comorbidities was grouped as 0, 1, or ≥2. Outcomes were defined as improvement in exercise capacity (maximal exercise capacity, 6-minute walk test, and constant workload cycle exercise duration) and quality of life (Chronic Respiratory Questionnaire)...
April 12, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28399976/copd-care-in-saudi-arabia-physicians-awareness-and-knowledge-of-guidelines-and-barriers-to-implementation
#9
M E Alsubaiei, P A Frith, P A Cafarella, S Quinn, M S Al Moamary, R D McEvoy, T W Effing
OBJECTIVE: To assess Saudi physicians' awareness and knowledge about chronic obstructive pulmonary disease (COPD) guideline recommendations. METHODS: Cross-sectional study including physicians involved in COPD care in five hospitals in the Eastern Province of Saudi Arabia. The level of physicians' knowledge was considered as satisfactory (score > 80%), fair (score 50-80%) or poor (<50% of total score). RESULTS: Among the 44 physicians included in the study, the mean ± standard deviation knowledge score was 29...
May 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28384911/occurrence-of-anxiety-and-depression-among-stable-copd-patients-and-its-impact-on-functional-capability
#10
Debabani Biswas, Subhasis Mukherjee, Rajarshi Chakroborty, Somsubhra Chatterjee, Subrata Rath, Runa Das, Shabana Begum
INTRODUCTION: Anxiety and depression are important but often under-diagnosed co-morbid conditions in patients with Chronic Obstructive Pulmonary Disease (COPD) which may affect the functional capacity of the patients. AIM: To find out the proportion of depression and anxiety among stable COPD patients using a validated questionnaire suitable for use in clinic and the factors affecting their reduced functional capability as assessed by six-minute walk test. MATERIALS AND METHODS: This was a descriptive cross-sectional study...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28380186/diaphragmatic-mobility-relationship-with-lung-function-respiratory-muscle-strength-dyspnea-and-physical-activity-in-daily-life-in-patients-with-copd
#11
Flávia Roberta Rocha, Ana Karla Vieira Brüggemann, Davi de Souza Francisco, Caroline Semprebom de Medeiros, Danielle Rosal, Elaine Paulin
Objective: To evaluate diaphragmatic mobility in relation to lung function, respiratory muscle strength, dyspnea, and physical activity in daily life (PADL) in patients with COPD. Methods: We included 25 patients with COPD, classified according to the Global Initiative for Chronic Obstructive Lung Disease criteria, and 25 healthy individuals. For all of the participants, the following were evaluated: anthropometric variables, spirometric parameters, respiratory muscle strength, diaphragmatic mobility (by X-ray), PADL, and the perception of dyspnea...
January 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28370700/determinants-of-annual-change-in-physical-activity-in-copd
#12
Christian F Clarenbach, Noriane A Sievi, Sarah R Haile, Thomas Brack, Martin H Brutsche, Martin Frey, Sarosh Irani, Jörg D Leuppi, Robert Thurnheer, Malcolm Kohler
BACKGROUND AND OBJECTIVE: Daily physical activity (PA) is reduced in patients with COPD. Previous cross-sectional analyses indicate various predictors for a low level of PA including airway obstruction, exacerbations and co-morbidities. However, information from longitudinal studies evaluating PA in the context of disease progression, survival and co-morbidities is scant. METHODS: In a heterogeneous cohort of COPD patients, we annually assessed the number of steps per day over 1 week and potential determinants including lung function, exacerbations and co-morbidities...
March 30, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28368706/resting-physiological-correlates-of-reduced-exercise-capacity-in-smokers-with-mild-airway-obstruction
#13
Amany F Elbehairy, Azmy Faisal, Jordan A Guenette, Dennis Jensen, Katherine A Webb, Rashid Ahmed, J Alberto Neder, Denis E O'Donnell
Smokers with minor spirometric abnormalities can experience persistent activity-related dyspnea and exercise intolerance. Additional resting tests can expose heterogeneous physiological abnormalities, but their relevance and association with clinical outcomes remain uncertain. Subjects included sixty-two smokers (≥20 pack-years), with cough and/or dyspnea and minor airway obstruction [forced expiratory volume in one-second (FEV1) ≥80% predicted and >5th percentile lower limit of normal (LLN) (i.e., z-score >-1...
April 3, 2017: COPD
https://www.readbyqxmd.com/read/28360517/greater-dyspnea-is-associated-with-lower-health-related-quality-of-life-among-european-patients-with-copd
#14
Jean-Bernard Gruenberger, Jeffrey Vietri, Dorothy L Keininger, Donald A Mahler
OBJECTIVE: Dyspnea is a defining symptom in the classification and treatment of chronic obstructive pulmonary disease (COPD). However, the degree of variation in burden among symptomatic COPD patients and the possible correlates of burden remain unclear. This study was conducted to characterize patients in Europe currently being treated for COPD according to the level of dyspnea in terms of sociodemographics, health-related quality of life, work productivity impairment, and health care resource use assessed by patient reports...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28356730/plasminogen-activator-inhibitor-1-is-elevated-in-patients-with-copd-independent-of-metabolic-and-cardiovascular-function
#15
Benjamin Waschki, Henrik Watz, Olaf Holz, Helgo Magnussen, Beata Olejnicka, Tobias Welte, Klaus F Rabe, Sabina Janciauskiene
INTRODUCTION: Plasminogen activator inhibitor-1 (PAI-1), a major inhibitor of fibrinolysis, is associated with thrombosis, obesity, insulin resistance, dyslipidemia, and premature aging, which all are coexisting conditions of chronic obstructive pulmonary disease (COPD). The role of PAI-1 in COPD with respect to metabolic and cardiovascular functions is unclear. METHODS: In this study, which was nested within a prospective cohort study, the serum levels of PAI-1 were cross-sectionally measured in 74 stable COPD patients (Global Initiative for Chronic Obstructive Lung Disease [GOLD] Stages I-IV) and 18 controls without lung disease...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28352087/feasibility-and-applicability-of-the-paper-and-electronic-copd-assessment-test-cat-and-the-clinical-copd-questionnaire-ccq-in-primary-care-a-clinimetric-study
#16
J W H Kocks, C M G Blom, M J Kasteleyn, W Oosterom, B J Kollen, T Van der Molen, N H Chavannes
Three questionnaires are recommended in the management of chronic obstructive pulmonary disease by the global initiative for obstructive lung disease, of which two are the more comprehensive assessments: the chronic obstructive pulmonary disease assessment test and the clinical chronic obstructive pulmonary disease questionnaire. Both are carefully designed high-quality questionnaires, but information on the feasibility for routine use is scarce. The aim of this study was to compare the time to complete the chronic obstructive pulmonary disease assessment test and the clinical chronic obstructive pulmonary disease questionnaire and the acceptability of the questionnaires...
March 28, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28331305/colds-as-predictors-of-the-onset-and-severity-of-copd-exacerbations
#17
Neil W Johnston, Marita Olsson, Staffan Edsbäcker, Maria Gerhardsson de Verdier, Per Gustafson, Christopher McCrae, Peter V Coyle, R Andrew McIvor
RATIONALE: Common colds are associated with acute respiratory symptom exacerbations in COPD patients. OBJECTIVE: To determine exacerbation risk and severity in COPD patients with/without coincident self-reported colds. METHODS: Global initiative for chronic Obstructive Lung Disease stage I-IV COPD patients electronically transmitted respiratory symptom diaries to research staff daily between December 2006 and April 2009. Respiratory symptom worsening prompted contact by a study nurse and patient assessment to determine if a cold was present or an exacerbation underway...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28326854/subclinical-carotid-atherosclerosis-in-patients-with-chronic-obstructive-pulmonary-disease-a-meta-analysis-of-literature-studies
#18
Pasquale Ambrosino, Roberta Lupoli, Giovanni Cafaro, Salvatore Iervolino, Mauro Carone, Nicola Pappone, Matteo Nicola Dario Di Minno
BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients have an increased cardiovascular (CV) morbidity and mortality. Common carotid intima-media thickness (CCA-IMT) and carotid plaques are surrogate markers of subclinical atherosclerosis and predictors of CV events. METHODS AND RESULTS: We performed a meta-analysis to evaluate the association between COPD and subclinical atherosclerosis. Studies evaluating the impact of COPD on CCA-IMT and on the prevalence of carotid plaques were systematically searched...
April 17, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28326177/characterization-of-secondary-care-for-copd-in-sweden
#19
Josefin Sundh, Christer Janson, Gunnar Johansson, Anders Lindén, Claes-Göran Löfdahl, Thomas Sandström, Kjell Larsson
Introduction: Only a selected proportion of chronic obstructive pulmonary disease (COPD) patients are managed in secondary care. The aim of this study was to characterize disease severity, treatment and structure of secondary care for COPD in Sweden. Methods: Information was collected from 29 of 33 existing secondary care units of respiratory medicine in Sweden, using both individual data from 373 consecutively enrolled COPD patients with Global initiative on Obstructive Lung Disease (GOLD) stage III-IV and a structural questionnaire about available resources at the units...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28306326/classification-of-airflow-limitation-based-on-z-score-underestimates-mortality-in-patients-with-chronic-obstructive-pulmonary-disease
#20
Elena Tejero, Eva Prats, Raquel Casitas, Raúl Galera, Paloma Pardo, Adelaida Gavilán, Elisabet Martínez-Cerón, Carolina Cubillos-Zapata, Luis Del Peso, Francisco García-Río
RATIONALE: Global Lung Function Initiative recommends reporting lung function measures as z-score, and a classification of airflow limitation (AL) based on this parameter has recently been proposed. OBJECTIVE: To evaluate the prognostic capacity of the AL classifications based on z-score or percentage predicted in patients with chronic obstructive pulmonary disease (COPD). METHODS: A cohort of 2614 COPD patients recruited outside the hospital setting was examined after 57±13 months of follow-up, totalling 10,322 person-years...
March 17, 2017: American Journal of Respiratory and Critical Care Medicine
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