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https://www.readbyqxmd.com/read/29143096/-neurofeedback-for-the-treatment-of-chronic-tinnitus-review-and-future-perspectives
#1
REVIEW
T Kleinjung, C Thüring, D Güntensperger, P Neff, M Meyer
Neurofeedback is a noninvasive neuromodulation technique employing real-time display of brain activity in terms of electroencephalography (EEG) signals to teach self-regulation of distinct patterns of brain activity or influence brain activity in a targeted manner. The benefit of this approach for control of symptoms in attention deficit disorders, hyperactivity, depression, and migraine has been proven. Studies in recent years have also repeatedly shown this treatment to improve tinnitus symptoms, although it has not become established as routine therapy...
November 15, 2017: HNO
https://www.readbyqxmd.com/read/29134344/a-cross-sectional-study-of-the-relationship-between-blood-lead-levels-and-reported-attention-deficit-disorder-an-assessment-of-the-economic-impact-on-the-united-states
#2
David A Geier, Janet K Kern, Mark R Geier
Attention deficit disorder (ADD) is characterized by a pattern of inattention and/or impulsivity that is inconsistent with developmental level and interferes with normal functioning in at least two settings. A recent meta-analysis suggested a significant relationship between lead (Pb) exposure and attention deficit symptoms. This study evaluated the potential relationship between increasing blood Pb levels and the risk of a reported ADD diagnosis. This cross-sectional study examined a sample of 2109 persons (32,762,158 weighted-persons) between 10 and 19 years-old from the 2003-2004 National Health and Nutritional Examination Survey (NHANES)...
November 13, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29122229/-study-of-genetic-variants-in-the-bdnf-comt-dat1-and-sert-genes-in-colombian-children-with-attention-deficit-disorder
#3
Jenny Ortega-Rojas, Carlos E Arboleda-Bustos, Luis Morales, Bruno A Benítez, Diana Beltrán, Álvaro Izquierdo, Humberto Arboleda, Rafael Vásquez
BACKGROUND: Attention deficit and hyperactive disorder (ADHD) is highly prevalent among children in Bogota City. Both genetic and environmental factors play a very important role in the etiology of ADHD. However, to date few studies have addressed the association of genetic variants and ADHD in the Colombian population. OBJECTIVES: To test the genetic association between polymorphisms in the DAT1, HTTLPR, COMT and BDNF genes and ADHD in a sample from Bogota City...
October 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/29107289/disruption-of-the-homeodomain-transcription-factor-orthopedia-homeobox-otp-is-associated-with-obesity-and-anxiety
#4
Lee Moir, Elena G Bochukova, Rebecca Dumbell, Gareth Banks, Rasneer S Bains, Patrick M Nolan, Cheryl Scudamore, Michelle Simon, Kimberly A Watson, Julia Keogh, Elana Henning, Audrey Hendricks, Stephen O'Rahilly, Inês Barroso, Adrienne E Sullivan, David C Bersten, Murray L Whitelaw, Susan Kirsch, Elizabeth Bentley, I Sadaf Farooqi, Roger D Cox
OBJECTIVE: Genetic studies in obese rodents and humans can provide novel insights into the mechanisms involved in energy homeostasis. METHODS: In this study, we genetically mapped the chromosomal region underlying the development of severe obesity in a mouse line identified as part of a dominant N-ethyl-N-nitrosourea (ENU) mutagenesis screen. We characterized the metabolic and behavioral phenotype of obese mutant mice and examined changes in hypothalamic gene expression...
November 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/29067802/ultrasensitive-and-selective-organic-fet-type-nonenzymatic-dopamine-sensor-based-on-platinum-nanoparticles-decorated-reduced-graphene-oxide
#5
Jungkyun Oh, Jun Seop Lee, Jaemoon Jun, Sung Gun Kim, Jyongsik Jang
Dopamine (DA), a catecholamine hormone, is an important neurotransmitter that controls renal and cardiovascular organizations and regulates physiological activities. Abnormal concentrations of DA cause unfavorable neuronal illnesses such as Parkinson's disease, schizophrenia, and attention deficit hyperactivity disorder/attention deficit disorder. However, the DA concentration is exceedingly low in patients and difficult to detect with existing biosensors. In this study, we developed an organic field-effect-transistor-type (OFET) nonenzyme biosensor using platinum nanoparticle-decorated reduced graphene oxide (Pt_rGO) for ultrasensitive and selective DA detection...
November 2, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29036309/chiral-analysis-of-methamphetamine-in-oral-fluid-samples-a-method-to-distinguish-licit-from-illicit-drug-use
#6
Damon Borg, Elizabeth Kolb, Cindy Lantigua, Richard Stripp
Methamphetamine (MAMP) is a popular illicit drug abused for its central nervous system stimulating effects. MAMP is also used therapeutically in the treatment of overeating disorders, narcolepsy, attention deficit disorder, in over-the-counter (OTC) products to ease nasal congestion. MAMP exists in two enantiomeric forms, dextrorotary (d-MAMP) or levorotary (l-MAMP). The compounds are similar in chemical structure, simply differing in the orientation of functional groups around the asymmetric carbon. In part because of the availability of l-MAMP in OTC nasal inhalers, forensic guidelines require a sample to contain greater than 20% d-MAMP to consider illicit drug use when interpreting results...
September 25, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/28975530/a-case-series-on-the-potential-effect-of-omega-3-fatty-acid-supplementation-on-24-h-heart-rate-variability-and-its-circadian-variation-in-children-with-attention-deficit-hyperactivity-disorder
#7
Reiner Buchhorn, Julian Koenig, Marc N Jarczok, Hanna Eichholz, Christian Willaschek, Julian F Thayer, Michael Kaess
Attention deficit disorder with and without hyperactivity (ADHD) in children is associated with decreased 24-h heart rate variability (HRV). Previous research has shown that supplementation of omega-3-fatty acid increases HRV. Here, we aimed to investigate whether the supplementation of omega-3-fatty acids would increase 24-h HRV in an uncontrolled case series of children with ADHD. HRV was recorded in 18 children and adolescents (age 13.35 ± 2.8 years) before and after omega-3 supplementation. Preliminary results indicate that omega-3 supplementation in children with AD(H)D may reduce mean heart rate and increase its variability...
October 3, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28963436/novel-nr2f1-variants-likely-disrupt-dna-binding-molecular-modeling-in-two-cases-review-of-published-cases-genotype-phenotype-correlation-and-phenotypic-expansion-of-the-bosch-boonstra-schaaf-optic-atrophy-syndrome
#8
Charu Kaiwar, Michael T Zimmerman, Matthew J Ferber, Zhiyv Niu, Raul A Urrutia, Eric W Klee, Dusica Babovic-Vuksanovic
Bosch-Boonstra-Schaaf Optic Atrophy Syndrome (BBSOAS) is a recently described autosomal dominant disorder caused by mutations in NR2F1 gene. There are presently 28 cases of BBSOAS described in the literature. Its common features include developmental delay, intellectual disability, hypotonia, optic nerve atrophy, attention deficit disorder, autism spectrum disorder, seizures, hearing defects, spasticity and thinning of the corpus callosum. Here we report two unrelated probands with novel, de novo, missense variants in NR2F1 The first is a 14-year-old male patient with hypotonia, intellectual disability, optic nerve hypoplasia, delayed bone age, short stature, and altered neurotransmitter levels on CSF testing...
September 28, 2017: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/28939535/reading-difficulties-and-the-pediatric-ophthalmologist
#9
EDITORIAL
Sheryl M Handler, Walter M Fierson
Approximately 20% of children have dyslexia, a language-based reading disability. A variation in language processing in the brain leads to a deficit in phonological (auditory) processing, which leads to problems in learning to read, write, and spell. Myths continue to exist regarding dyslexia and vision, and although eye and vision problems may coexist with dyslexia, they are not more prevalent than in the general population. Rarely vision problems may make reading at near very difficult and may masquerade as a learning problem or attention deficit disorder/attention deficit hyperactivity disorder...
September 19, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28894435/neuroactive-steroids-receptor-interactions-and-responses
#10
REVIEW
Kald Beshir Tuem, Tesfay Mehari Atey
Neuroactive steroids (NASs) are naturally occurring steroids, which are synthesized centrally as de novo from cholesterol and are classified as pregnane, androstane, and sulfated neurosteroids (NSs). NASs modulate many processes via interacting with gamma-aminobutyric acid (GABA), N-methyl-d-aspartate, serotonin, voltage-gated calcium channels, voltage-dependent anion channels, α-adrenoreceptors, X-receptors of the liver, transient receptor potential channels, microtubule-associated protein 2, neurotrophin nerve growth factor, and σ1 receptors...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28853132/prevalence-of-attention-deficit-hyperactivity-disorder-among-school-aged-children-in-jordan
#11
Manar Al Azzam, Mohammed Al Bashtawy, Ahmad Tubaishat, Abdul-Monim Batiha, Loai Tawalbeh
The purpose of this study was to determine the prevalence of attention deficit hyperactivity disorder (ADHD) symptoms among school children in Jordan and the probable associated risk factors. This was a crosssectional descriptive study and simple random sampling was used to select 480 students, aged 6-12 years, from government primary schools in Mafraq City, Jordan. Data were collected using the modified Arabic version of the Attention Deficit Disorder Evaluation Scale (ADDES) school version and parental questionnaire...
August 27, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/28846801/increased-illness-burden-in-women-with-comorbid-bipolar-and-premenstrual-dysphoric-disorder-data-from-1-099-women-from-step-bd-study
#12
A Slyepchenko, B N Frey, B Lafer, A A Nierenberg, G S Sachs, R S Dias
BACKGROUND: The impact of comorbid premenstrual dysphoric disorder (PMDD) in women with bipolar disorder (BD) is largely unknown. AIMS: We compared illness characteristics and female-specific mental health problems between women with BD with and without PMDD. MATERIALS & METHODS: A total of 1 099 women with BD who participated in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) were studied. Psychiatric diagnoses and illness characteristics were assessed using the Mini International Neuropsychiatric Interview...
November 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28818147/attention-deficit-hyperactivity-disorder-and-fatal-accidents-in-aviation-medicine
#13
Tanja Laukkala, Robert Bor, Bruce Budowle, Antti Sajantila, Pooshan Navathe, Markku Sainio, Alpo Vuorio
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with symptoms of inattention and/or hyperactivity-impulsivity that interfere with functioning and/or development. ADHD occurs in about 2.5% of adults. ADHD can be an excluding medical condition among pilots due to the risk of attentional degradation and therefore impact on flight safety. Diagnosis of ADHD is complex, which complicates aeromedical assessment. This study highlights fatal accident cases among pilots with ADHD and discusses protocols to detect its presence to help to assess its importance to flight safety...
September 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28796977/a-novel-de-novo-20q13-11q13-12-microdeletion-in-a-boy-with-neurodevelopmental-disorders-case-report
#14
Joanna Bernaciak, Barbara Wiśniowiecka-Kowalnik, Jennifer Castañeda, Anna Kutkowska-Kaźmierczak, Beata Nowakowska
Copy-number variants (CNVs) are an important cause of human neurodevelopmental disorders. We present the first case of a 424 kb de novo 20q13.11q13.12 microdeletion in a patient with attention deficit disorder, tics and autistic behaviors, such as emotional and behavioral problems, and movement stereotypes. This region includes three genes expressed in the brain: SFRS6, PTPRT and L3MBTL. Our results suggest that loss of the chromosomal region 20q13.11q13.12 is causative for the clinical findings observed in the patient...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28770564/poverty-in-the-usa-and-asthma-autism-and-attention-deficit-disorder
#15
David Isaacs
No abstract text is available yet for this article.
August 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28709018/adhd-research-in-india-a-narrative-review
#16
REVIEW
Pooja Patnaik Kuppili, Harshini Manohar, Raman Deep Pattanayak, Rajesh Sagar, Balaji Bharadwaj, Preeti Kandasamy
INTRODUCTION: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with no clear etiopathogenesis. Owing to unique socio cultural milieu of India, it is worthwhile reviewing research on ADHD from India and comparing findings with global research. Thereby, we attempted to provide a comprehensive overview of research on ADHD from India. METHODS: A boolean search of articles published in English from September 1966 to January 2017 on electronic search engines Google Scholar, PubMed, IndMED, MedIND, using the search terms "ADHD", "Attention Deficit and Hyperactivity Disorder", "Hyperactivity" ,"Child psychiatry", "Hyperkinetic disorder", "Attention Deficit Disorder", "India"was carried out and peer - reviewed studies conducted among human subjects in India were included for review...
July 5, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28706166/-development-and-effects-of-an-instructional-coaching-program-regarding-children-with-attention-deficit-hyperactivity-disorder-for-elementary-school-teachers
#17
Shin Jeong Park, Wan Ju Park
PURPOSE: The aim of this study was to identify the effects of a newly developed instructional coaching program regarding Attention Deficit Hyperactivity Disorder (ADHD) for teachers. METHODS: Seventy teachers participated in this study involving a nonequivalent control group and a pretest-posttest design. The instructional coaching program consisted of eight 60-minute sessions. The program was developed through a theoretical development program involving six steps...
June 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28705637/-do-children-with-attention-deficit-and-hyperactivity-disorder-adhd-have-a-diferent-gait-pattern-relationship-between-idiopathic-toe-walking-and-adhd
#18
Víctor Soto Insuga, Beatriz Moreno Vinués, Rebeca Losada Del Pozo, María Rodrigo Moreno, Marta Martínez González, Raquel Cutillas Ruiz, Carmen Mateos Carmen
INTRODUCTION: Idiopathic toe-walking (ITW) is described as a gait pattern with no contact between the heels and the ground in children older than 3years. The diagnosis is clinical, making it necessary to rule out other neurological and orthopaedic conditions. A relationship between ITW and vestibular dysfunction and/or proprioceptive sensibility has been proposed. Children with neurodevelopmental disorders (autism, language and cognitive disorders) often have ITW. OBJECTIVES: To determine the frequency of ITW in children with attention deficit disorder and hyperactivity (ADHD)...
July 10, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28701934/neuronal-intra-individual-variability-masks-response-selection-differences-between-adhd-subtypes-a-need-to-change-perspectives
#19
Annet Bluschke, Witold X Chmielewski, Moritz Mückschel, Veit Roessner, Christian Beste
Due to the high intra-individual variability in attention deficit/hyperactivity disorder (ADHD), there may be considerable bias in knowledge about altered neurophysiological processes underlying executive dysfunctions in patients with different ADHD subtypes. When aiming to establish dimensional cognitive-neurophysiological constructs representing symptoms of ADHD as suggested by the initiative for Research Domain Criteria, it is crucial to consider such processes independent of variability. We examined patients with the predominantly inattentive subtype (attention deficit disorder, ADD) and the combined subtype of ADHD (ADHD-C) in a flanker task measuring conflict control...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28693958/childhood-obesity-obesity-treatment-outcome-and-achieved-education-a-prospective-cohort-study
#20
Emilia Hagman, Pernilla Danielsson, Lena Brandt, Viktoria Svensson, Anders Ekbom, Claude Marcus
PURPOSE: Childhood obesity represents a social burden. This study aims to investigate whether achieved educational level differs in young adults who have suffered obesity in childhood compared with the general population and to determine how obesity treatment influences achieved educational level. METHODS: This prospective cohort study includes subjects from the Swedish Childhood Obesity Treatment Registry (BORIS, n = 1,465) who were followed up after 20 years of age...
October 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
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