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https://www.readbyqxmd.com/read/28894435/neuroactive-steroids-receptor-interactions-and-responses
#1
REVIEW
Kald Beshir Tuem, Tesfay Mehari Atey
Neuroactive steroids (NASs) are naturally occurring steroids, which are synthesized centrally as de novo from cholesterol and are classified as pregnane, androstane, and sulfated neurosteroids (NSs). NASs modulate many processes via interacting with gamma-aminobutyric acid (GABA), N-methyl-d-aspartate, serotonin, voltage-gated calcium channels, voltage-dependent anion channels, α-adrenoreceptors, X-receptors of the liver, transient receptor potential channels, microtubule-associated protein 2, neurotrophin nerve growth factor, and σ1 receptors...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28853132/prevalence-of-attention-deficit-hyperactivity-disorder-among-school-aged-children-in-jordan
#2
Manar Al Azzam, Mohammed Al Bashtawy, Ahmad Tubaishat, Abdul-Monim Batiha, Loai Tawalbeh
The purpose of this study was to determine the prevalence of attention deficit hyperactivity disorder (ADHD) symptoms among school children in Jordan and the probable associated risk factors. This was a crosssectional descriptive study and simple random sampling was used to select 480 students, aged 6-12 years, from government primary schools in Mafraq City, Jordan. Data were collected using the modified Arabic version of the Attention Deficit Disorder Evaluation Scale (ADDES) school version and parental questionnaire...
August 27, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/28846801/increased-illness-burden-in-women-with-comorbid-bipolar-and-premenstrual-dysphoric-disorder-data-from-1-099-women-from-step-bd-study
#3
A Slyepchenko, B N Frey, B Lafer, A A Nierenberg, G S Sachs, R S Dias
BACKGROUND: The impact of comorbid premenstrual dysphoric disorder (PMDD) in women with bipolar disorder (BD) is largely unknown. AIMS: We compared illness characteristics and female-specific mental health problems between women with BD with and without PMDD. MATERIALS & METHODS: A total of 1 099 women with BD who participated in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) were studied. Psychiatric diagnoses and illness characteristics were assessed using the Mini International Neuropsychiatric Interview...
August 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28818147/attention-deficit-hyperactivity-disorder-and-fatal-accidents-in-aviation-medicine
#4
Tanja Laukkala, Robert Bor, Bruce Budowle, Antti Sajantila, Pooshan Navathe, Markku Sainio, Alpo Vuorio
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder with symptoms of inattention and/or hyperactivity-impulsivity that interfere with functioning and/or development. ADHD occurs in about 2.5% of adults. ADHD can be an excluding medical condition among pilots due to the risk of attentional degradation and therefore impact on flight safety. Diagnosis of ADHD is complex, which complicates aeromedical assessment. This study highlights fatal accident cases among pilots with ADHD and discusses protocols to detect its presence to help to assess its importance to flight safety...
September 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28796977/a-novel-de-novo-20q13-11q13-12-microdeletion-in-a-boy-with-neurodevelopmental-disorders-case-report
#5
Joanna Bernaciak, Barbara Wiśniowiecka-Kowalnik, Jennifer Castañeda, Anna Kutkowska-Kaźmierczak, Beata Nowakowska
Copy-number variants (CNVs) are an important cause of human neurodevelopmental disorders. We present the first case of a 424 kb de novo 20q13.11q13.12 microdeletion in a patient with attention deficit disorder, tics and autistic behaviors, such as emotional and behavioral problems, and movement stereotypes. This region includes three genes expressed in the brain: SFRS6, PTPRT and L3MBTL. Our results suggest that loss of the chromosomal region 20q13.11q13.12 is causative for the clinical findings observed in the patient...
2017: Developmental Period Medicine
https://www.readbyqxmd.com/read/28770564/poverty-in-the-usa-and-asthma-autism-and-attention-deficit-disorder
#6
David Isaacs
No abstract text is available yet for this article.
August 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28709018/adhd-research-in-india-a-narrative-review
#7
REVIEW
Pooja Patnaik Kuppili, Harshini Manohar, Raman Deep Pattanayak, Rajesh Sagar, Balaji Bharadwaj, Preeti Kandasamy
INTRODUCTION: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder with no clear etiopathogenesis. Owing to unique socio cultural milieu of India, it is worthwhile reviewing research on ADHD from India and comparing findings with global research. Thereby, we attempted to provide a comprehensive overview of research on ADHD from India. METHODS: A boolean search of articles published in English from September 1966 to January 2017 on electronic search engines Google Scholar, PubMed, IndMED, MedIND, using the search terms "ADHD", "Attention Deficit and Hyperactivity Disorder", "Hyperactivity" ,"Child psychiatry", "Hyperkinetic disorder", "Attention Deficit Disorder", "India"was carried out and peer - reviewed studies conducted among human subjects in India were included for review...
July 5, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28706166/-development-and-effects-of-an-instructional-coaching-program-regarding-children-with-attention-deficit-hyperactivity-disorder-for-elementary-school-teachers
#8
Shin Jeong Park, Wan Ju Park
PURPOSE: The aim of this study was to identify the effects of a newly developed instructional coaching program regarding Attention Deficit Hyperactivity Disorder (ADHD) for teachers. METHODS: Seventy teachers participated in this study involving a nonequivalent control group and a pretest-posttest design. The instructional coaching program consisted of eight 60-minute sessions. The program was developed through a theoretical development program involving six steps...
June 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28705637/-do-children-with-attention-deficit-and-hyperactivity-disorder-adhd-have-a-diferent-gait-pattern-relationship-between-idiopathic-toe-walking-and-adhd
#9
Víctor Soto Insuga, Beatriz Moreno Vinués, Rebeca Losada Del Pozo, María Rodrigo Moreno, Marta Martínez González, Raquel Cutillas Ruiz, Carmen Mateos Carmen
INTRODUCTION: Idiopathic toe-walking (ITW) is described as a gait pattern with no contact between the heels and the ground in children older than 3years. The diagnosis is clinical, making it necessary to rule out other neurological and orthopaedic conditions. A relationship between ITW and vestibular dysfunction and/or proprioceptive sensibility has been proposed. Children with neurodevelopmental disorders (autism, language and cognitive disorders) often have ITW. OBJECTIVES: To determine the frequency of ITW in children with attention deficit disorder and hyperactivity (ADHD)...
July 10, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28701934/neuronal-intra-individual-variability-masks-response-selection-differences-between-adhd-subtypes-a-need-to-change-perspectives
#10
Annet Bluschke, Witold X Chmielewski, Moritz Mückschel, Veit Roessner, Christian Beste
Due to the high intra-individual variability in attention deficit/hyperactivity disorder (ADHD), there may be considerable bias in knowledge about altered neurophysiological processes underlying executive dysfunctions in patients with different ADHD subtypes. When aiming to establish dimensional cognitive-neurophysiological constructs representing symptoms of ADHD as suggested by the initiative for Research Domain Criteria, it is crucial to consider such processes independent of variability. We examined patients with the predominantly inattentive subtype (attention deficit disorder, ADD) and the combined subtype of ADHD (ADHD-C) in a flanker task measuring conflict control...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28693958/childhood-obesity-obesity-treatment-outcome-and-achieved-education-a-prospective-cohort-study
#11
Emilia Hagman, Pernilla Danielsson, Lena Brandt, Viktoria Svensson, Anders Ekbom, Claude Marcus
PURPOSE: Childhood obesity represents a social burden. This study aims to investigate whether achieved educational level differs in young adults who have suffered obesity in childhood compared with the general population and to determine how obesity treatment influences achieved educational level. METHODS: This prospective cohort study includes subjects from the Swedish Childhood Obesity Treatment Registry (BORIS, n = 1,465) who were followed up after 20 years of age...
October 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28665917/brief-psychosis-induced-by-methylphenidate-in-a-child-with-attention-deficit-disorder-a-case-report-and-literature-review
#12
Juan Carlos Martínez-Aguayo, Marcelo Arancibia, Nicolás Meza-Concha, Camila Bustamante, Javier Pérez-Bracchiglione, Eva Madrid
Methylphenidate-induced psychosis has been scarcely studied due to bioethical and neurobiological issues regarding its research. Although some authors have hypothesized that there might be a vulnerability for the development of a major psychiatric disorder in the long term, there is no agreement about the predictive value of this type of psychosis in children and adolescents, and its origin is also uncertain. It has been suggested that higher dopamine levels in some cerebral regions and a family history of mental disorders might increase the risk of psychosis secondary to psychostimulants...
June 21, 2017: Medwave
https://www.readbyqxmd.com/read/28661952/victimization-by-siblings-in-children-with-disability-or-weight-problems
#13
Corinna J Tucker, David Finkelhor, Heather Turner
OBJECTIVE: Children with a physical disability, psychological disorder, or of nonnormative weight are often targets of peer victimization. Sibling victimization, however, is more common than peer victimization, but rarely explored. We investigated linkages between sibling victimization and whether children had a physical disability, psychological disorder (i.e., internalizing disorder, attention deficit disorder/attention-deficit hyperactivity disorder), and were perceived by parents as being thinner than average or overweight...
July 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28620324/description-of-various-factors-contributing-to-traffic-accidents-in-youth-and-measures-proposed-to-alleviate-recurrence
#14
REVIEW
Ludovic Gicquel, Pauline Ordonneau, Emilie Blot, Charlotte Toillon, Pierre Ingrand, Lucia Romo
Traffic accidents are the leading cause of hospitalization in adolescence, with the 18-24-year-old age group accounting for 23% of deaths by traffic accidents. Recurrence rate is also high. One in four teenagers will have a relapse within the year following the first accident. Cognitive impairments known in adolescence could cause risky behaviors, defined as repetitive engagement in dangerous situations such as road accidents. Two categories of factors seem to be associated with traffic accidents: (1) factors specific to the traffic environment and (2) "human" factors, which seem to be the most influential...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28548194/-heritability-and-genetic-comorbidity-of-attention-deficit-disorder-with-hyperactivity
#15
REVIEW
Giannina Puddu, Paula Rothhammer, Ximena Carrasco, Francisco Aboitiz, Francisco Rothhammer
This review aims to summarize information about the genetic etiology of attention deficit disorder with hyperactivity (ADHD), with particular reference to the contributions of our research group. We also discuss the genetic comorbidity estimated from genome-wide single nucleotide polymorphisms (SNP´s) between ADHD and major psychiatric disorders such as schizophrenia (E), major depressive disorder (MDD), bipolar disorder (BD) and autism spectrum disorders (ASD). A high genetic comorbidity was found between E and BD (46%), a moderate comorbidity between MDD and E, MDD and BD and MDD and ADHD (18%, 22% and 10% respectively) and a low comorbidity between E and ASD (2...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28542667/-ign-complementary-alternative-medicine-in-adolescents-with-attention-deficit-hyperactivity-disorder-and-mood-disorders
#16
María Pilar Pérez Carmona
The Complementary/Alternative Medicine (CAM) have been increasingly used by patients such as children and adolescents. The Ministry of Health in Chile (MINSAL) has recognized and regulated some CAM, although there is still unknown their effectiveness and safety of these. OBJECTIVE: Review the available evidence regarding the use of CAM in adolescents with the attention deficit hyperactivity syndrome (ADHD) and mood disorders. METHODOLOGY: A review of the related literature about this topic on PubMed, focus on the last 10 years and using as a keywords Complementary/Alternative Medicine/Therapies, Attention deficit disorder with hyperactivity, Mood disorders, and Children/Adolescents...
April 2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28542319/shared-and-differentiated-motor-skill-impairments-in-children-with-dyslexia-and-or-attention-deficit-disorder-from-simple-to-complex-sequential-coordination
#17
Marie-Ève Marchand-Krynski, Olivier Morin-Moncet, Anne-Marie Bélanger, Miriam H Beauchamp, Gabriel Leonard
Dyslexia and Attention deficit disorder (AD) are prevalent neurodevelopmental conditions in children and adolescents. They have high comorbidity rates and have both been associated with motor difficulties. Little is known, however, about what is shared or differentiated in dyslexia and AD in terms of motor abilities. Even when motor skill problems are identified, few studies have used the same measurement tools, resulting in inconstant findings. The present study assessed increasingly complex gross motor skills in children and adolescents with dyslexia, AD, and with both Dyslexia and AD...
2017: PloS One
https://www.readbyqxmd.com/read/28539852/abnormal-brain-connectivity-spectrum-disorders-following-thimerosal-administration-a-prospective-longitudinal-case-control-assessment-of-medical-records-in-the-vaccine-safety-datalink
#18
David A Geier, Janet K Kern, Kristin G Homme, Mark R Geier
BACKGROUND: Autism spectrum disorder (ASD), tic disorder (TD), and hyperkinetic syndrome of childhood (attention deficit disorder [ADD]/attention deficit hyperactivity disorder [ADHD]) are disorders recently defined as abnormal connectivity spectrum disorders (ACSDs) because they show a similar pattern of abnormal brain connectivity. This study examines whether these disorders are associated with exposure to thimerosal, a mercury (Hg)-based preservative. METHODS: A hypothesis testing case-control study evaluated the Vaccine Safety Datalink for the potential dose-dependent odds ratios (ORs) for diagnoses of ASD, TD, and ADD/ADHD compared to controls, following exposure to Hg from thimerosal-containing Haemophilus influenzae type b vaccines administrated within the first 15 months of life...
January 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/28534123/attention-deficit-hyperactivity-disorder-symptoms-and-psychological-comorbidity-in-eating-disorder-patients
#19
L Sala, G Martinotti, M L Carenti, L Romo, M Oumaya, A Pham-Scottez, F Rouillon, P Gorwood, L Janiri
PURPOSE: There is some evidence that eating disorders (ED) and Attention-deficit/hyperactivity disorder (ADHD) share common clinical features and that ADHD might contribute to the severity of eating disorders. A greater understanding of how the presence of comorbid ADHD may affect the psychopathological framework of eating disorder seems of primary importance. The aim of our study was to evaluate rates of ADHD in three ED subgroups of inpatients: anorexia nervosa restricting type (AN-R), anorexia nervosa binge-eating/purging type (AN-BP) and bulimia nervosa (BN)...
May 22, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28492169/-learning-disorders-in-adhd-how-are-they-related
#20
P Fourneret, H Poissant
Learning difficulties in general and learning disabilities in particular are almost constant in attention deficit disorder with or without hyperactivity (ADHD). Despite a major research effort, the extent and diversity of these comorbid events still raise many questions about the exact nature of their pathogenetic condition (simple consequences of ADHD or specific related disorders?) and consequently the best way to support them. This article aims to present a brief review of the current data.
December 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
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