Gabrielle M Henriques, Alexia Anjos-Santos, Isa R S Rodrigues, Victor Nascimento-Rocha, Henrique S Reis, Matheus Libarino-Santos, Thaísa Barros-Santos, Thais S Yokoyama, Natalia B Bertagna, Cristiane A Favoretto, Célia R G Moraes, Fábio C Cruz, Paulo C R Barbosa, Eduardo A V Marinho, Alexandre J Oliveira-Lima, Laís F Berro
Ibogaine is a psychedelic extracted from the plant Tabernanthe iboga Baill. (Apocynaceae) , natural from Africa, and has been proposed as a potential treatment for substance use disorders. In animal models, ibogaine reduces ethanol self-administration. However, no study to date has investigated the effects of ibogaine on ethanol-induced conditioned place preference (CPP). The present study aimed to investigate the effects of repeated treatment with ibogaine on the reinstatement of CPP to ethanol in male mice...
2021: Frontiers in Pharmacology