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https://www.readbyqxmd.com/read/27921300/living-in-violent-neighbourhoods-is-associated-with-gestational-weight-gain-outside-the-recommended-range
#1
Jessica Galin, Barbara Abrams, Stephanie A Leonard, Ellicott C Matthay, Dana E Goin, Jennifer Ahern
BACKGROUND: During pregnancy, most women do not meet gestational weight gain (GWG) guidelines, potentially resulting in adverse maternal and infant health consequences. Social environment determinants of GWG have been identified, but evidence on the relationship between neighbourhood violence and GWG is scant. Our study aims to examine the relationship between neighbourhood violence and GWG outside the recommended range. METHODS: We used statewide vital statistics and health care utilization data from California for 2006-12 (n = 2 364 793) to examine the relationship of neighbourhood violence (quarters of zip-code rates of homicide and assault) in the first 37 weeks of pregnancy with GWG (categorized using the Institute of Medicine's pregnancy weight gain guidelines)...
December 6, 2016: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/27913887/transcriptomics-analysis-of-hulless-barley-during-grain-development-with-a-focus-on-starch-biosynthesis
#2
Yawei Tang, Xingquan Zeng, Yulin Wang, Lijun Bai, Qijun Xu, Zexiu Wei, Hongjun Yuan, Tashi Nyima
Hulless barley, with its unique nutritional value and potential health benefits, has increasingly attracted attentions in recent years. However, the transcription dynamics during hulless barley grain development is not well understood. In the present study, we investigated the transcriptome changes during barley grain development using Illumina paired-end RNA-sequencing. Two datasets of the developing grain transcriptomes from two barley landraces with the differential seed starch synthesis traits were generated, and comparative transcriptome approach in both genotypes was performed...
December 2, 2016: Functional & Integrative Genomics
https://www.readbyqxmd.com/read/27913067/the-financial-impact-of-clinic-no-show-rates-in-an-academic-pediatric-otolaryngology-practice
#3
Zhen Huang, Mariam Ashraf, Heather Gordish-Dressman, Pamela Mudd
PURPOSE: To investigate determinants of no-show rates in an academic pediatric otolaryngology practice including appointment time, age, sex, new patient status, payer mix, and median household income by zip code. MATERIALS AND METHODS: Retrospective chart review of clinic no-show rates and patient demographics in a free standing children's hospital and affiliated outpatient clinics across eight providers in a one-year period. RESULTS: Analysis shows that the overall no-show rate across all providers was 15% with the highest rate of 19% in the zip code with the lowest median income...
November 23, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27913065/hpv-status-cancer-stem-cell-marker-expression-hypoxia-gene-signatures-and-tumour-volume-identify-good-prognosis-subgroups-in-patients-with-hnscc-after-primary-radiochemotherapy-a-multicentre-retrospective-study-of-the-german-cancer-consortium-radiation-oncology
#4
Annett Linge, Fabian Lohaus, Steffen Löck, Alexander Nowak, Volker Gudziol, Chiara Valentini, Cläre von Neubeck, Martin Jütz, Inge Tinhofer, Volker Budach, Ali Sak, Martin Stuschke, Panagiotis Balermpas, Claus Rödel, Anca-Ligia Grosu, Amir Abdollahi, Jürgen Debus, Ute Ganswindt, Claus Belka, Steffi Pigorsch, Stephanie E Combs, David Mönnich, Daniel Zips, Frank Buchholz, Daniela E Aust, Gustavo B Baretton, Howard D Thames, Anna Dubrovska, Jan Alsner, Jens Overgaard, Mechthild Krause, Michael Baumann
OBJECTIVE: To investigate the impact of the tumour volume, HPV status, cancer stem cell (CSC) marker expression and hypoxia gene signatures, as potential markers of radiobiological mechanisms of radioresistance, in a contemporary cohort of patients with locally advanced head and neck squamous cell carcinoma (HNSCC), who received primary radiochemotherapy (RCTx). MATERIALS AND METHODS: For 158 patients with locally advanced HNSCC of the oral cavity, oropharynx or hypopharynx who were treated at six DKTK partner sites, the impact of tumour volume, HPV DNA, p16 overexpression, p53 expression, CSC marker expression and hypoxia-associated gene signatures on outcome of primary RCTx was retrospectively analyzed...
November 29, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27912681/how-valid-are-wearable-physical-activity-trackers-for-measuring-steps
#5
Hyun-Sung An, Gregory C Jones, Seoung-Ki Kang, Gregory J Welk, Jung-Min Lee
Wearable activity trackers have become popular for tracking individual's daily physical activity, but little information is available to substantiate the validity of these devices in step counts. Thirty-five healthy individuals completed three conditions of activity tracker measurement: walking/jogging on a treadmill, walking over-ground on an indoor track, and a 24-hour free-living condition. Participants wore 10 activity trackers at the same time for both treadmill and over-ground protocol. Of these 10 activity trackers three were randomly given for 24-hour free-living condition...
December 2, 2016: European Journal of Sport Science
https://www.readbyqxmd.com/read/27909945/individual-differences-in-diurnal-preference-and-time-of-exercise-interact-to-predict-exercise-frequency
#6
Garrett C Hisler, Alison L Phillips, Zlatan Krizan
BACKGROUND: Diurnal preference (and chronotype more generally) has been implicated in exercise behavior, but this relation has not been examined using objective exercise measurements nor have potential psychosocial mediators been examined. Furthermore, time-of-day often moderates diurnal preference's influence on outcomes, and it is unknown whether time-of-exercise may influence the relation between chronotype and exercise frequency. PURPOSE: The current study examined whether individual differences in diurnal preference ("morningness-eveningness") predict unique variance in exercise frequency and if commonly studied psychosocial variables mediate this relation (i...
December 1, 2016: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/27904939/-time-interval-between-neoadjuvant-radiochemotherapy-and-surgery-in-rectal-cancer-no-impact-on-the-pathologic-complete-response-rate
#7
Cihan Gani, Daniel Zips
No abstract text is available yet for this article.
November 30, 2016: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/27900355/data-taken-from-the-review-article-radiation-and-circulatory-disease-and-used-in-the-associated-meta-analysis
#8
Mark P Little
This WinZip archive 'Combined R, EpiWin & datafiles (rev 2016-9-29).zip' contains the basic data used in the meta-analysis of doi 10.1016/j.mrrev.2016.07.008 (M.P. Little, 2016) [1], complete with R (R Project version 3.2.2, 2015) [2] code used for meta-regression etc. The basic data is derived from the papers of Mulrooney et al. (D.A. Mulrooney, M.W. Yeazel, T. Kawashima, A.C. Mertens, P. Mitby, M. Stovall, S.S. Donaldson, D.M. Green, C.A. Sklar, L.L. Robison, W.M. Leisenring, 2009) [3], Cutter et al. (D.J...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27899206/the-use-of-thrombolysis-for-acute-pulmonary-embolism-in-the-united-states-national-trends-and-patient-characteristics-from-2006-to-2011
#9
Barret Rush, Katie Wiskar, Landon Berger, Donald E Griesdale
BACKGROUND: Thrombolysis for the treatment of pulmonary embolism (PE) has received significant attention in the literature over the past 10 years. OBJECTIVE: Our primary objective was to examine the trend in thrombolysis use in the United States from 2006 to 2011. Secondary objectives include examining patient and hospital characteristics associated with receiving thrombolysis and rates of complications associated with thrombolysis. METHODS: In this retrospective cohort study, we used the Nationwide Inpatient Sample from 2006 to 2011 to identify patients with a diagnosis of PE who received or did not receive thrombolytic agents...
November 26, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27898859/regional-and-seasonal-analyses-of-weights-in-growing-angus-cattle
#10
H L Bradford, B O Fragomeni, J K Bertrand, D A L Lourenco, I Misztal
This study evaluated the impact of region and season on growth in Angus seed stock. To assess geographic differences, the United States was partitioned into 9 regions based on similar climate and topography related to cow-calf production. Seasonal effects were associated with the month that animals were weighed. The American Angus Association provided growth data, and records were assigned to regions based on the owner's zip code. Most Angus cattle were in the Cornbelt, Lower Plains, Rocky Mountain, Upper Plains, and Upper South regions, with proportionally fewer Angus in Texas compared with the national cow herd...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27894189/ziprasidone-induces-cytotoxicity-and-genotoxicity-in-human-peripheral-lymphocytes
#11
Haluk Kefelioğlu, Zülal Atlı Şekeroğlu, Gamze Coşguner, Seval Kontaş Yedier, Vedat Şekeroğlu
It has been stated that some antipsychotic drugs might cause genotoxic and carcinogenic effects. Ziprasidone (ZIP) is commonly used an antipsychotic drug. However, its genotoxicity and carcinogenicity data are very limited. The cytotoxicity and genotoxicity of ZIP on human peripheral blood lymphocytes were examined in vitro by sister chromatid exchange (SCE), chromosome aberration (CA) and micronucleus (MN) tests in this study. Lymphocyte cultures were treated with 50, 75 and 100 μg/ml of ZIP in the presence and absence of a metabolic activator (S9 mix)...
November 29, 2016: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/27893581/the-effect-of-socioeconomic-status-and-parental-demographics-on-activation-of-department-of-child-and-family-services-in-pediatric-burn-injury
#12
Jessica K Campos, Yee M Wong, Brittany N Hasty, Kelly A McElligott, Michael J Mosier
Burns resulting from child maltreatment are tragic causes of significant morbidity and mortality, most commonly affecting children under 3 years of age. More than one third of nonaccidental burns occur in single-parent homes or have parents with history of mental illness, substance abuse, incarceration, or Department of Children and Family Services (DCFS) involvement. The authors sought to profile pediatric burn injuries associated with DCFS investigations. They performed a retrospective chart review of pediatric burn patients, admitted between January 1, 2011 and December 31, 2014...
November 11, 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27891781/geographic-distribution-of-live-births-with-tetralogy-of-fallot-in-north-carolina-2003-to-2012
#13
Jennifer S Nelson, Rebecca C Stebbins, Paula D Strassle, Robert E Meyer
BACKGROUND: Geographic variation in congenital heart disease is not well-described. This study uses geographic information systems (GIS) to describe the spatial epidemiology of tetralogy of Fallot (TOF), in North Carolina (NC) and to compare travel time for cases to congenital heart centers in NC. METHODS: Using the NC Birth Defects Monitoring Program database, live births with TOF born between 2003 and 2012 were identified. Birth certificates provided demographic variables...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27888122/the-sunflower-transcription-factor-hahb11-confers-tolerance-to-water-deficit-and-salinity-to-transgenic-arabidopsis-and-alfalfa-plants
#14
Julieta V Cabello, Jorge I Giacomelli, María C Gómez, Raquel L Chan
Homeodomain-leucine zipper (HD-Zip) transcription factors are unique to the plant kingdom; members of subfamily I are known to be involved in abiotic stress responses. HaHB11 belongs to this subfamily and it was previously shown that it is able to confer improved yield and tolerance to flooding via a quiescent strategy. Here we show that HaHB11 expression is induced by ABA, NaCl and water deficit in sunflower seedlings and leaves. Arabidopsis transgenic plants expressing HaHB11, controlled either by its own promoter or by the constitutive 35S CaMV, presented rolled leaves and longer roots than WT when grown under standard conditions...
November 22, 2016: Journal of Biotechnology
https://www.readbyqxmd.com/read/27887621/pediatric-emergency-department-visits-and-ambient-air-pollution-in-the-u-s-state-of-georgia-a-case-crossover-study
#15
Qingyang Xiao, Yang Liu, James A Mulholland, Armistead G Russell, Lyndsey A Darrow, Paige E Tolbert, Matthew J Strickland
BACKGROUND: Estimating the health effects of ambient air pollutant mixtures is necessary to understand the risk of real-life air pollution exposures. METHODS: Pediatric Emergency Department (ED) visit records for asthma or wheeze (n = 148,256), bronchitis (n = 84,597), pneumonia (n = 90,063), otitis media (n = 422,268) and upper respiratory tract infection (URI) (n = 744,942) were obtained from Georgia hospitals during 2002-2008. Spatially-contiguous daily concentrations of 11 ambient air pollutants were estimated from CMAQ model simulations that were fused with ground-based measurements...
November 25, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27885880/decreased-zinc-in-the-development-and-progression-of-malignancy-an-important-common-relationship-and-potential-for-prevention-and-treatment-of-carcinomas
#16
Leslie C Costello, Renty B Franklin
Efficacious chemotherapy does not exist for treatment or prevention of prostate, liver, and pancreatic carcinomas, and some other cancers that exhibit decreased zinc in malignancy. Zinc treatment offers a potential solution; but its support has been deterred by adverse bias. Areas covered: 1. The clinical and experimental evidence for the common ZIP transporter/Zn down regulation in these cancers. 2. The evidence for a zinc approach to prevent and/or treat these carcinomas. 3. The issues that introduce bias against support for the zinc approach...
December 5, 2016: Expert Opinion on Therapeutic Targets
https://www.readbyqxmd.com/read/27885590/payment-reform-needed-to-address-health-disparities-of-undiagnosed-diabetic-retinopathy-in-the-city-of-chicago
#17
Dustin D French, Jess J Behrens, Kathryn L Jackson, Abel N Kho, Theresa L Walunas, Charlesnika T Evans, Michael Mbagwu, Curtis E Margo, Paul J Bryar
INTRODUCTION: The Affordable Care Act (ACA) has expanded health coverage for thousands of Illinois residents. Expanded coverage, however, does not guarantee appropriate health care. Diabetes and its ocular complications serve as an example of how providers in underserved urban areas may not be able to keep up with new demand for labor- and technology-intensive health care unless changes in reimbursement policies are instituted. METHODS: A retrospective cohort study was conducted using medical encounter information from the Chicago HealthLNK Data Repository (HDR), an assembly of non-duplicated and de-identified patient medical records...
November 24, 2016: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/27884187/a-simulation-study-to-quantify-the-impacts-of-exposure-measurement-error-on-air-pollution-health-risk-estimates-in-copollutant-time-series-models
#18
Kathie L Dionisio, Howard H Chang, Lisa K Baxter
BACKGROUND: Exposure measurement error in copollutant epidemiologic models has the potential to introduce bias in relative risk (RR) estimates. A simulation study was conducted using empirical data to quantify the impact of correlated measurement errors in time-series analyses of air pollution and health. METHODS: ZIP-code level estimates of exposure for six pollutants (CO, NOx, EC, PM2.5, SO4, O3) from 1999 to 2002 in the Atlanta metropolitan area were used to calculate spatial, population (i...
November 25, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27879349/ncam1-polysialylation-the-prion-protein-s-elusive-reason-for-being
#19
REVIEW
Mohadeseh Mehrabian, Herbert Hildebrandt, Gerold Schmitt-Ulms
Much confusion surrounds the physiological function of the cellular prion protein (PrP(C)). It is, however, anticipated that knowledge of its function will shed light on its contribution to neurodegenerative diseases and suggest ways to interfere with the cellular toxicity central to them. Consequently, efforts to elucidate its function have been all but exhaustive. Building on earlier work that uncovered the evolutionary descent of the prion founder gene from an ancestral ZIP zinc transporter, we recently investigated a possible role of PrP(C) in a morphogenetic program referred to as epithelial-to-mesenchymal transition (EMT)...
December 2016: ASN Neuro
https://www.readbyqxmd.com/read/27876235/high-altitude-is-an-independent-risk-factor-for-postoperative-symptomatic-venous-thromboembolism-after-knee-arthroscopy-a-matched-case-control-study-of-medicare-patients
#20
Jourdan M Cancienne, David R Diduch, Brian C Werner
PURPOSE: To use a national database of Medicare patients to evaluate the association of uncomplicated knee arthroscopy performed at high altitude with the incidence of postoperative venous thromboembolism (VTE). METHODS: The 100% Medicare Standard Analytical File database was queried for all patients undergoing isolated arthroscopic partial meniscectomy and/or chondroplasty from 2005-2012. Patients with more complex open or additional arthroscopic knee procedures, a personal history of VTE, or any hypercoagulable state were excluded...
November 18, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
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