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https://www.readbyqxmd.com/read/28716344/what-global-maternal-and-child-nutrition-can-learn-from-animal-science
#1
Cesar G Victora, Reynaldo Martorell, Sindura Ganapathi, R Dean Boyd, Dale E Bauman, Jack Odle
No abstract text is available yet for this article.
August 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28715286/effects-of-lifestyle-intervention-on-soluble-cd163-a-macrophage-activation-marker-in-patients-with-non-alcoholic-fatty-liver-disease
#2
Sidsel Rødgaard-Hansen, Alexis St George, Konstantin Kazankov, Adrian Bauman, Jacob George, Henning Grønbæk, Holger Jon Møller
OBJECTIVE: Liver macrophages play an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Soluble CD163 (sCD163), a macrophage-specific biomarker, reflects disease activity in the range of liver diseases. The impact of lifestyle intervention on sCD163 in adult NAFLD patients has not been investigated. MATERIAL AND METHODS: We assessed 126 NAFLD patients participating in a lifestyle intervention study for sCD163 concentrations at baseline, after the three-month intervention period, and at long-term follow-up after 12 and 24 months...
July 17, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/28707805/decreased-parvalbumin-mrna-levels-in-cerebellar-purkinje-cells-in-autism
#3
Jean-Jacques Soghomonian, Kunzhong Zhang, Sujithra Reprakash, Gene J Blatt
Recent neuropathology studies in human brains indicate that several areas of the prefrontal cortex have decreased numbers of parvalbumin interneurons or decreased parvalbumin expression in Autism Spectrum disorders (ASD) [Hashemi, Ariza, Rogers, Noctor, & Martinez-Cerdeno, 2017; Zikopoulos & Barbas, ]. These data suggest that a deficit in parvalbumin may be a key neuropathology of ASD and contribute to altered GABAergic inhibition. However, it is unclear if a deficit in parvalbumin is a phenomenon that occurs in regions other than the cerebral cortex...
July 14, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28699836/blogs-and-the-art-of-dying-blogging-with-and-about-severe-cancer-in-late-modern-swedish-society
#4
Yvonne Andersson
In recent years, the common and mundane dying has begun to take place in the public space of the Internet. Among the blogs about food, fashion, travel, and other joyful aspects of life, blogs about severe disease and dying have appeared. The aim of this article is to describe some characteristic features of a sample of cancer blogs and to discuss them in the light of Zygmunt Bauman's theory of the rationalization of death in modernity and theories about networked media, especially the theories about "affective labor" and "ambient intimacy" by McCosker, Darcy, and Pfister...
January 1, 2017: Omega
https://www.readbyqxmd.com/read/28699368/impact-of-blood-pressure-lesion-level-and-physical-activity-on-aortic-augmentation-index-in-persons-with-sci
#5
Caitlyn G Katzelnick, Joseph P Weir, Nancy Chiaravalotti, Glenn Wylie, Trevor Dyson-Hudson, William A Bauman, Jill M Wecht
Individuals with chronic spinal cord injury (SCI) are at a heightened risk of cardiovascular disease (CVD) due to autonomic nervous system dysfunction, physical inactivity and increased inflammatory processes. Arterial stiffness (AS) is recognized as an independent risk factor for CVD and, specifically, pulse wave analysis (PWA) has proven to be a useful tool to predict and track structural arterial changes that reflect arteriosclerosis. The augmentation index (AI) can be used to estimate AS and is derived from the amplitude and timing of the blood pressure (BP) wave reflection in a peripheral artery...
July 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28691106/recombinant-myostatin-reduces-highly-expressed-micrornas-in-differentiating-c2c12-cells
#6
Zachary A Graham, Rita De Gasperi, William A Bauman, Christopher P Cardozo
Myostatin is small glycopeptide that is produced and secreted by skeletal muscle. It is a potent negative regulator of muscle growth that has been associated with conditions of frailty. In C2C12 cells, myostatin limits cell differentiation. Myostatin acts through activin receptor IIB, activin receptor-like kinase (ALK) and Smad transcription factors. microRNAs (miRNA) are short, 22 base pair nucleotides that bind to the 3' UTR of target mRNA to repress translation or reduce mRNA stability. In the present study, expression in differentiating C2C12 cells of the myomiRs miR-1 and 133a were down-regulated following treatment with 1 μg of recombinant myostatin at 1 d post-induction of differentiation while all myomiRs (miR-1, 133a/b and 206) were upregulated by SB431542, a potent ALK4/5/7 inhibitor which reduces Smad2 signaling, at 1 d and all, with the exception of miR-206, were upregulated by SB431542 at 3 d...
March 2017: Biochemistry and Biophysics Reports
https://www.readbyqxmd.com/read/28688679/long-term-toxicities-in-10-year-survivors-of-radiation-treatment-for-head-and-neck-cancer
#7
Yanqun Dong, John A Ridge, Tianyu Li, Miriam N Lango, Thomas M Churilla, Jessica R Bauman, Thomas J Galloway
OBJECTIVES: To characterize the recognized but poorly understood long-term toxicities of radiation therapy (RT) for head and neck cancer (HNC). MATERIALS AND METHODS: We retrospectively evaluated patients treated with curative-intent RT for HNC between 1990 and 2005 at a single institution with systematic multidisciplinary follow-up ≥10years. Long-term toxicities of the upper aerodigestive tract were recorded and assigned to two broad categories: pharyngeal-laryngeal and oral cavity toxicity...
August 2017: Oral Oncology
https://www.readbyqxmd.com/read/28681032/patient-and-nonradiographic-tumor-characteristics-predicting-lipid-poor-angiomyolipoma-in-small-renal-masses-introducing-the-bears-index
#8
Tyler M Bauman, Aaron M Potretzke, Alec J Wright, Joel M Vetter, Theodora A Potretzke, R Sherburne Figenshau
PURPOSE: To create a simple model using clinical variables for predicting lipid-poor angiomyolipoma (AML) in patients with small renal masses presumed to be renal cell carcinoma (RCC) from preoperative imaging. MATERIALS AND METHODS: A series of patients undergoing partial nephrectomy (PN) for renal masses ≤4 cm was identified using a prospectively maintained database. Patients were excluded if standard preoperative imaging was not consistent with RCC. Chi square and Mann-Whitney U analyses were used to evaluate differences in characteristics between patients with AML and other types of pathology...
July 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28673047/assessing-community-health-an-innovative-tool-for-measuring-height-and-length
#9
Ashley Bauman, Kacey Ernst, Mary Hayden, Denise J Roe, Rachel Murray, Maurice Agawo, Stephen Munga, Erik Schmahl, Douglas Taren
Anthropometric measurements, including height and length, are routinely needed for health research worldwide. Measurement boards are the current gold standard for obtaining the height and length of children. In community-based research, however, the size and weight of the measurement boards make them difficult and cumbersome to carry in the field. In addition, children and infants may express an unwillingness to be placed onto the measurement board. Electronic measuring tools commonly used in industry and contracting work are precise and portable...
June 30, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28671307/cutaneous-microvascular-perfusion-responses-to-insulin-iontophoresis-are-differentially-affected-by-insulin-resistance-after-spinal-cord-injury
#10
Michael F La Fountaine, Christopher M Cirnigliaro, Frank Azarello, Joshua C Hobson, Oriana Tascione, Kirsten N Swonger, Trevor Dyson-Hudson, William A Bauman
Endothelial-mediated mechanisms that regulate skin blood flow may play an integral role in optimizing skin perfusion in vascular beds with sympathetic nervous system vasomotor impairment, such as in spinal cord injury (SCI). Insulin is a vasoactive hormone and second messenger of nitric oxide that facilitates endothelial-mediated dilatation. The effects of insulin resistance (IR) on sublesional cutaneous perfusion responses to insulin provocation have yet to be described in persons with SCI. Persons with SCI and an able-bodied (AB) cohort were divided into subgroups based upon fasting plasma insulin (FPI) concentration cut-offs for IR (≥13...
July 3, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28665308/substrate-oxide-layer-thickness-optimization-for-a-dual-width-plasmonic-grating-for-surface-enhanced-raman-spectroscopy-sers-biosensor-applications
#11
Stephen J Bauman, Zachary T Brawley, Ahmad A Darweesh, Joseph B Herzog
This work investigates a new design for a plasmonic SERS biosensor via computational electromagnetic models. It utilizes a dual-width plasmonic grating design, which has two different metallic widths per grating period. These types of plasmonic gratings have shown larger optical enhancement than standard single-width gratings. The new structures have additional increased enhancement when the spacing between the metal decreases to sub-10 nm dimensions. This work integrates an oxide layer to improve the enhancement even further by carefully studying the effects of the substrate oxide thickness on the enhancement and reports ideal substrate parameters...
June 30, 2017: Sensors
https://www.readbyqxmd.com/read/28662069/dog-ownership-and-all-cause-mortality-in-a-population-cohort-in-norway-the-hunt-study
#12
Magnhild Oust Torske, Steinar Krokstad, Emmanuel Stamatakis, Adrian Bauman
OBJECTIVE: There has been increased interest in human-animal interactions and their possible effects on human health. Some of this research has focused on human physical activity levels, mediated through increased dog walking. Much of the reported research has been cross sectional, and very few epidemiological studies have examined the association between dog ownership and mortality in populations. METHODS: We used data from the Norwegian county population-based Nord-Trøndelag HUNT Study (HUNT2, 1995-1997)...
2017: PloS One
https://www.readbyqxmd.com/read/28654350/use-of-telehealth-videoconferencing-in-pediatric-type-1-diabetes-in-oregon
#13
Ines Guttmann-Bauman, Joannie Kono, Amber Laurie Lin, Katrina L Ramsey, Bruce A Boston
INTRODUCTION: We reviewed the impact of telehealth videoconferencing clinics on outcomes of care in pediatric patients with type 1 diabetes in rural Oregon. METHODS: We performed a chart review as well as the review of patient satisfaction questionnaires from 27 patients seen in the first year of the program. RESULTS: The number of yearly visits to diabetes clinic increased from average 1.5 to 2.7, which was statistically significant (p < 0...
June 27, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28652280/immune-related-adverse-events-as-a-biomarker-in-non-melanoma-patients-treated-with-programmed-cell-death-1-inhibitors
#14
Julia Judd, Matthew Zibelman, Elizabeth Handorf, John O'Neill, Chethan Ramamurthy, Sasini Bentota, Jamie Doyle, Robert G Uzzo, Jessica Bauman, Hossein Borghaei, Elizabeth R Plimack, Ranee Mehra, Daniel M Geynisman
BACKGROUND: The programmed death 1 (PD-1) checkpoint inhibitors (CKIs) can lead to immune-related adverse events (irAEs). We sought to evaluate whether the development of irAEs correlates with treatment response in non-melanoma malignancies. MATERIALS AND METHODS: We conducted a retrospective study of patients who received anti-PD-1 CKI monotherapy at Fox Chase Cancer Center. Endpoints included overall response rate (ORR), time to next therapy or death (TTNTD), and overall survival (OS)...
June 26, 2017: Oncologist
https://www.readbyqxmd.com/read/28648930/associations-between-multiple-indicators-of-socio-economic-status-and-muscle-strengthening-activity-participation-in-a-nationally-representative-population-sample-of-australian-adults
#15
Jonathan Freeston, Joanne Gale, Yorgi Mavros, Jason A Bennie, Zeljko Pedisic, Adrian E Bauman, Emmanuel Stamatakis
BACKGROUND: Muscle-strengthening activity (MSA) (e.g. weight training), confers unique health benefits. While socioeconomic status (SES) correlates with leisure time physical activity, little is known about its relation with MSA. METHODS: Cross-sectional study of a representative sample of 8993 Australian adults (>18years) who participated in the National Nutrition and Physical Activity Survey 2011-12. Information was collected on SES (income, education, socio-economic disadvantage and remoteness) and MSA participation...
June 22, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28643065/laparoscopic-distal-pancreatectomy-for-pancreatic-cancer-is-safe-and-effective
#16
Marita D Bauman, David G Becerra, E Molly Kilbane, Nicholas J Zyromski, C Max Schmidt, Henry A Pitt, Attila Nakeeb, Michael G House, Eugene P Ceppa
PURPOSE: To compare the short-term and oncologic outcomes of patients with pancreatic ductal adenocarcinoma (PDAC) undergoing laparoscopic distal pancreatectomy (LDP) and open distal pancreatectomy (ODP). METHODS: Consecutive cases of distal pancreatectomy (DP) (n = 422) were reviewed at a single high-volume institution over a 10-year period (2005-2014). Inclusion criteria consisted of any patient with PDAC by surgical pathology. Ninety-day outcomes were monitored through a prospectively maintained pancreatic resection database...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28640780/challenges-in-acute-care-surgery-shootout-at-the-o-k-corral-history-revisited
#17
Gary A Vercruysse, Zachary M Bauman, Jordan Roman, Peter M Rhee, Ernest E Moore
No abstract text is available yet for this article.
June 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28635968/sex-biased-dispersal-creates-spatial-genetic-structure-in-a-parthenogenetic-ant-with-a-dependent-lineage-reproductive-system
#18
A Kuhn, D Bauman, H Darras, S Aron
Reproduction and dispersal are key aspects of species life history that influence spatial genetic structure in populations. Several ant species in the genus Cataglyphis have evolved a unique breeding system in which new reproductives (that is, queens and males) are produced asexually by parthenogenesis; in contrast, non-reproductives (that is, workers) are produced via sexual reproduction by mates from distinct genetic lineages. We investigated how these two coexisting reproductive methods affect population-level spatial genetic structure using the ant Cataglyphis mauritanica as a model...
June 21, 2017: Heredity
https://www.readbyqxmd.com/read/28635121/exposure-to-sodium-valproate-during-pregnancy-facial-features-and-signs-of-autism
#19
Rachel Stadelmaier, Hanah Nasri, Curtis K Deutsch, Margaret Bauman, Anne Hunt, Christopher J Stodgell, Jane Adams, Lewis B Holmes
BACKGROUND: Valproic acid (VPA) is the most teratogenic anticonvulsant drug in clinical use today. Children exposed prenatally to VPA have previously been shown to have dysmorphic craniofacial features, identified subjectively but not by anthropometric methods. Exposure to VPA has also been associated with an increased frequency of autism spectrum disorder (ASD). An increased cephalic index (the ratio of the cranial lateral width to the cranial anterior-posterior length) has been observed in children with ASD...
June 21, 2017: Birth defects research
https://www.readbyqxmd.com/read/28623677/incidence-of-cognitively-defined-late-onset-alzheimer-s-dementia-subgroups-from-a-prospective-cohort-study
#20
Paul K Crane, Emily Trittschuh, Shubhabrata Mukherjee, Andrew J Saykin, R Elizabeth Sanders, Eric B Larson, Susan M McCurry, Wayne McCormick, James D Bowen, Thomas Grabowski, Mackenzie Moore, Julianna Bauman, Alden L Gross, C Dirk Keene, Thomas D Bird, Laura E Gibbons, Jesse Mez
INTRODUCTION: There may be biologically relevant heterogeneity within typical late-onset Alzheimer's dementia. METHODS: We analyzed cognitive data from people with incident late-onset Alzheimer's dementia from a prospective cohort study. We determined individual averages across memory, visuospatial functioning, language, and executive functioning. We identified domains with substantial impairments relative to that average. We compared demographic, neuropathology, and genetic findings across groups defined by relative impairments...
June 15, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
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