keyword
MENU ▼
Read by QxMD icon Read
search

Snake envenomation

keyword
https://www.readbyqxmd.com/read/28920799/presumptive-pit-viper-envenomation-in-psittacines-in-a-brazilian-zoo
#1
Mathias Dislich, Peter Wohlsein, Anna Sophie Croukamp, Ulrich Neumann
Snake bites represent a serious public health risk in many regions of the globe, especially in tropical areas. Clinical signs and postmortem changes are well described in human and other mammalian species. However, detailed case reports about venomous snake attacks in avian species are limited. This report describes presumptive fatal envenomations in three psittacines caused by pit vipers in a Brazilian zoo. In one case, a Brazilian lancehead (Bothrops moojeni) was captured in the aviary. In all three cases the dermis around the suspected snake bite area exhibited hemorrhages and edema...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28918605/food-or-threat-wild-capuchin-monkeys-sapajus-libidinosus-as-both-predators-and-prey-of-snakes
#2
Tiago Falótico, Michele P Verderane, Olívia Mendonça-Furtado, Noemi Spagnoletti, Eduardo B Ottoni, Elisabetta Visalberghi, Patrícia Izar
Snakes present a hazard to primates, both as active predators and by defensive envenomation. This risk might have been a selective pressure on the evolution of primate visual and cognitive systems, leading to several behavioral traits present in human and non-human primates, such as the ability to quickly learn to fear snakes. Primates seldom prey on snakes, and humans are one of the few primate species that do. We report here another case, the wild capuchin monkey (Sapajus libidinosus), which preys on snakes...
September 16, 2017: Primates; Journal of Primatology
https://www.readbyqxmd.com/read/28905944/snakebite-envenoming
#3
REVIEW
José María Gutiérrez, Juan J Calvete, Abdulrazaq G Habib, Robert A Harrison, David J Williams, David A Warrell
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty. Snake venoms are complex mixtures of proteins that exert a wide range of toxic actions. The high variability in snake venom composition is responsible for the various clinical manifestations in envenomings, ranging from local tissue damage to potentially life-threatening systemic effects...
September 14, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28904556/medicinal-plants-for-the-treatment-of-local-tissue-damage-induced-by-snake-venoms-an-overview-from-traditional-use-to-pharmacological-evidence
#4
REVIEW
Juliana Félix-Silva, Arnóbio Antônio Silva-Junior, Silvana Maria Zucolotto, Matheus de Freitas Fernandes-Pedrosa
Snakebites are a serious problem in public health due to their high morbimortality. Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims. The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects. Thus, the search for complementary alternatives for snakebite treatment is relevant. There are several reports of the popular use of medicinal plants against snakebites worldwide. In recent years, many studies have been published giving pharmacological evidence of benefits of several vegetal species against local effects induced by a broad range of snake venoms, including inhibitory potential against hyaluronidase, phospholipase, proteolytic, hemorrhagic, myotoxic, and edematogenic activities...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28889321/effects-of-purified-human-fibrinogen-modified-with-carbon-monoxide-and-iron-on-coagulation-in-rabbits-injected-with-crotalus-atrox-venom
#5
Vance G Nielsen
While snake venom derived enzymes, such as the thrombin-like activity possessing ancrod, have been used to treat thrombotic disease by defibrinogenating patients, the therapeutic potential of fibrinogenolytic snake venom enzymes, such as those derived from Crotalus atrox, have not been fully explored. However, one of the potential risks of administering fibrinogenolytic enzymes to effect defibrinogenation is hemorrhage secondary to hypofibrinogenemia. The present investigation sought to determine if human fibrinogen modified with carbon monoxide (CO) and iron (Fe) could resist degradation by C...
September 9, 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28887121/discovery-of-human-scfvs-that-cross-neutralize-the-toxic-effects-of-b-jararacussu-and-c-d-terrificus-venoms
#6
Luciano C Silva, Manuela B Pucca, Gabriela Pessenda, Lucas B Campos, Edson Z Martinez, Felipe A Cerni, José E Barbosa
Accidents involving venomous snakes are a public health problem worldwide, causing a large number of deaths per year. In Brazil, the majority of accidents are caused by the Bothrops and Crotalus genera, which are responsible for approximately 80% of severe envenoming cases. The cross-neutralization of snake venoms by antibodies is an important issue for development of more effective treatments. Our group has previously reported the construction of human monoclonal antibody fragments towards Bothrops jararacussu and Crotalus durissus terrificus' venoms...
September 5, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28878435/assessment-of-knowledge-about-snakebite-management-amongst-healthcare-providers-in-the-provincial-and-two-district-hospitals-in-savannakhet-province-lao-pdr
#7
Vongphoumy Inthanomchanh, Joshua A Reyer, Joerg Blessmen, Ketkesone Phrasisombath, Eiko Yamamoto, Nobuyuki Hamajima
Snakebite is a neglected condition and a common public health problem in Lao People's Democratic Republic (Lao PDR), with a high incidence of up to 1,105 cases per 100,000 persons per year. Snakebite patients with systemic envenoming do not receive effective treatment at local health facilities. Healthcare providers have only limited knowledge in assessing and providing the correct treatment for venomous snakebites. A cross-sectional study was conducted among 119 healthcare providers in Savannakhet Province, Lao PDR, with respect to their socio-demographic characteristics, knowledge of snake identification, and management of snakebite...
August 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28877511/severe-neurotoxicity-requiring-mechanical-ventilation-in-a-dog-envenomed-by-a-red-bellied-black-snake-pseudechis-porphyriacus-and-successful-treatment-with-an-experimental-bivalent-whole-equine-igg-antivenom
#8
A M Padula, E M Leister
Snakebite in dogs from Pseudechis porphyriacus (red-bellied black snake; RBBS) is a common envenomation treated by veterinarians in Australia where this snake occurs. This case report describes the successful treatment of a clinically severe RBBS envenomation in a dog with an experimental bivalent equine whole IgG antivenom and mechanical ventilation, following its presentation in a cyanotic state. The cause of the cyanosis and respiratory distress was considered due to paralysis from neurotoxins in RBBS venom...
September 4, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28843532/the-medical-threat-of-mamba-envenoming-in-sub-saharan-africa-revealed-by-genus-wide-analysis-of-venom-composition-toxicity-and-antivenomics-profiling-of-available-antivenoms
#9
Stuart Ainsworth, Daniel Petras, Mikael Engmark, Roderich D Süssmuth, Gareth Whiteley, Laura-Oana Albulescu, Taline D Kazandjian, Simon C Wagstaff, Paul Rowley, Wolfgang Wüster, Pieter C Dorrestein, Ana Silvia Arias, José M Gutiérrez, Robert A Harrison, Nicholas R Casewell, Juan J Calvete
Mambas (genus Dendroaspis) are among the most feared of the medically important elapid snakes found in sub-Saharan Africa, but many facets of their biology, including the diversity of venom composition, remain relatively understudied. Here, we present a reconstruction of mamba phylogeny, alongside genus-wide venom gland transcriptomic and high-resolution top-down venomic analyses. Whereas the green mambas, D. viridis, D. angusticeps, D. j. jamesoni and D. j. kaimosae, express 3FTx-predominant venoms, black mamba (D...
August 24, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28830752/eastern-brown-snake-pseudonaja-textilis-envenomation-in-dogs-and-cats-clinical-signs-coagulation-changes-brown-snake-venom-antigen-levels-and-treatment-with-a-novel-caprylic-acid-fractionated-bivalent-whole-igg-equine-antivenom
#10
A M Padula, E Leister
This report describes the diagnosis and treatment of 16 confirmed cases of snakebite from the Australian eastern brown snake (Pseudonaja textilis) in dogs and cats. The clinical signs, brown snake venom antigen concentrations, coagulation parameters, and treatment outcomes following administration of an experimental caprylic acid fractionated bivalent whole IgG antivenom are documented. A brown snake venom antigen specific sandwich ELISA was used to retrospectively quantify venom levels in serum and urine. The characteristic clinical signs of envenomation in all cases were neurotoxicity to a variable extent and coagulation disturbances...
August 19, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28830630/false-positive-immunoassay-for-acetyl-choline-receptor-antibody-achr-ab-in-patients-exposed-to-polyvalent-antisnake-venom
#11
Kaushik Sundar, Shankar Venkatasubramanian, Sundar Shanmugam, Preetam Arthur, Ramakrishnan Subbaraya, Philo Hazeena
Acute flaccid paralysis is a neuromuscular emergency characterized by rapidly worsening weakness that evolves quickly to cause diaphragmatic failure. The challenge for the treating physician is to stabilize the patient, generate the differential diagnosis and determine the management; all in quick time. Neurotoxic snake bites have inadequate signs of inflammation and are easily missed. Myasthenic crisis, on the other hand, could be the first sign of myasthenia gravis in up to 20% of patients. Both present with acute respiratory failure and inadequate history...
August 18, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28830248/naja-atra-snakebite-in-taiwan
#12
Yan-Chiao Mao, Po-Yu Liu, Liao-Chun Chiang, Chih-Sheng Lai, Kuo-Lung Lai, Cheng-Hsuan Ho, Te-Huo Wang, Chen-Chang Yang
BACKGROUND: Naja atra snakebite is uncommon in Taiwan and causes distinct effects on its victims. Although the Taiwan government produces its own specific antivenom, little information on the management of N. atra snakebite is available. MATERIALS AND METHODS: We retrospectively evaluated 183 patients admitted to two medical centers. Of these, 45 were identified as definite cases of N. atra snakebite, 86 as suspected cases, and 52 as clinical cases. Demographic data, symptomatology, and management were compared between these case groups...
August 23, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28827807/a-prospective-cohort-study-of-the-effectiveness-of-the-primary-hospital-management-of-all-snakebites-in-kurunegala-district-of-sri-lanka
#13
MULTICENTER STUDY
Seyed Shahmy, Senanayake A M Kularatne, Shantha S Rathnayake, Andrew H Dawson
INTRODUCTION: Sri Lanka records substantial numbers of snakebite annually. Primary rural hospitals are important contributors to health care. Health care planning requires a more detailed understanding of snakebite within this part of the health system. This study reports the management and epidemiology of all hospitalised snakebite in the Kurunegala district in Sri Lanka. METHODOLOGY: The district has 44 peripheral/primary hospitals and a tertiary care hospital-Teaching Hospital, Kurunegala (THK)...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28819275/a-novel-in-vitro-potency-assay-of-antisera-against-thai-naja-kaouthia-based-on-nicotinic-acetylcholine-receptor-binding
#14
Kavi Ratanabanangkoon, Pavinee Simsiriwong, Kritsada Pruksaphon, Kae Yi Tan, Sukanya Eursakun, Choo Hock Tan, Bunkuea Chantrathonkul, Wongsakorn Wongwadhunyoo, Sirida Youngchim, Nget Hong Tan
Snake envenomation is an important medical problem. One of the hurdles in antivenom development is the in vivo assay of antivenom potency which is expensive, gives variable results and kills many animals. We report a novel in vitro assay involving the specific binding of the postsynaptic neurotoxins (PSNTs) of elapid snakes with purified Torpedo californica nicotinic acetylcholine receptor (nAChR). The potency of an antivenom is determined by its antibody ability to bind and neutralize the PSNT, thus preventing it from binding to nAChR...
August 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28808936/-envenomation-by-micrurus-psyches-in-french-guiana
#15
X Heckmann, C Marty, F Starace, J-D Louembé, S Larréché
We report here the first known envenomation by Micrurus psyches, the so-called Carib coral snake, which occurred on April 2016 in the surroundings of Saint- Laurent-du-Maroni, Western French Guiana. Besides local neurological symptoms, it featured unexpected electrocardiogram changes, which were emergence of a first-degree atrioventricular block and biphasic T waves, both transient. NewWorld elapid venoms were not known for being cardiotoxic so far. The possible reasons of this cardiac injury are discussed.
August 14, 2017: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/28807018/the-neglected-burden-of-snakebites-in-cameroon-a-review-of-the-epidemiology-management-and-public-health-challenges
#16
Joel Noutakdie Tochie, Mazou N Temgoua, Tsi Njim, Danwang Celestin, Ronni Tankeu, Njinkeng J Nkemngu
OBJECTIVES: Snakebite is an underestimated medical and surgical emergency in developing countries responsible for a high disease burden. Optimal management of snake envenomation in these resource-limited settings is precluded by several public health challenges. In this review, we discuss the disease burden of snakebites in Cameroon and the public health challenges of its management in view of making recommendations essential for policy-making. MEDLINE, African Journals Online and Google Scholar were searched from January 1990 to February 2017 for studies addressing snakebite in Cameroon...
August 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28799698/retrospective-evaluation-of-cats-with-elapid-snake-envenomation-associated-neurotoxicity-requiring-mechanical-ventilation-12-cases-2005-2014
#17
Hui Mei Ong, Kylie Kelers, Dez Hughes, Manuel Boller
OBJECTIVE: To retrospectively determine the population and outcome characteristics of a cohort of Australian elapid snake envenomed cats requiring mechanical ventilation (MV). DESIGN: Retrospective observational study (2005-2014). SETTING: Academic veterinary emergency and critical care service. ANIMALS: Twelve cats undergoing MV for elapid snake envenomation. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The medical records were searched to identify cats requiring MV as part of treatment for elapid snake envenomation...
September 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28793021/the-epidemiology-of-snakebite-in-the-rio-grande-do-norte-state-northeastern-brazil
#18
Aluska Vieira Tavares, Kaliany Adja Medeiros de Araújo, Michael Radan de Vasconcelos Marques, Alecxandro Alves Vieira, Renner de Souza Leite
This report is a retrospective study of the epidemiology of snakebite cases recorded from 2007 to 2014 in the Rio Grande do Norte State, northeastern Brazil. Data was collected from the Injury Notification Information System database of the Health Department of Rio Grande do Norte. A total of 3,019 cases were studied. Cases were distributed over all months of the period studied and occurred mainly in rural areas. Snakes of the genus Bothrops, Crotalus, Micrurus, Lachesis and non-venomous snakes were responsible for 1,507, 185, 52, 6 and 673 cases, respectively...
2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28783135/enzymatic-and-pro-inflammatory-activities-of-bothrops-lanceolatus-venom-relevance-for-envenomation
#19
Marie Delafontaine, Isadora Maria Villas-Boas, Laurence Mathieu, Patrice Josset, Joël Blomet, Denise V Tambourgi
Bothrops lanceolatus, commonly named 'Fer-de-Lance', is an endemic snake of the French Caribbean Island of Martinique. Envenomations by B. lanceolatus present clinical aspects characterized by systemic thrombotic syndrome and important local inflammation, involving edema and pain but limited hemorrhage. To investigate mechanisms of venom-induced inflammation, B. lanceolatus venom was characterized, its cross-reactivity with bothropic antivenom explored, its cytotoxicity on human keratinocytes and vascular cells, and the production of cytokines and chemokines were analyzed...
August 7, 2017: Toxins
https://www.readbyqxmd.com/read/28767072/insights-into-the-mechanisms-involved-in-strong-hemorrhage-and-dermonecrosis-induced-by-atroxlysin-ia-a-pi-class-snake-venom-metalloproteinase
#20
Luciana Aparecida Freitas-de-Sousa, Mônica Colombini, Mônica Lopes-Ferreira, Solange M T Serrano, Ana Maria Moura-da-Silva
Hemorrhage is the most prominent effect of snake venom metalloproteinases (SVMPs) in human envenomation. The capillary injury is a multifactorial effect caused by hydrolysis of the components of the basement membrane (BM). The PI and PIII classes of SVMPs are abundant in viperid venoms and hydrolyze BM components. However, hemorrhage is associated mostly with PIII-class SVMPs that contain non-catalytic domains responsible for the binding of SVMPs to BM proteins, facilitating enzyme accumulation in the tissue and enhancing its catalytic efficiency...
August 2, 2017: Toxins
keyword
keyword
61267
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"