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Elective oocyte cryopreservation

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https://www.readbyqxmd.com/read/27922944/oocyte-vitrification-for-elective-fertility-preservation-the-past-present-and-future
#1
Vinay Gunnala, Glenn Schattman
PURPOSE OF REVIEW: Oocyte cryopreservation is no longer experimental and one of its rapidly growing indications is elective fertility preservation. Currently there is no sufficient evidence to support its practice and therefore its place in IVF remains uncertain. RECENT FINDINGS: Vitrification has superior post-thaw survival and fertilization outcomes compared with oocytes that were frozen with the slow-freeze technique. Oocyte vitrification produces similar IVF outcomes compared with fresh oocytes and is not associated with further obstetrical or perinatal morbidity...
December 5, 2016: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27672732/elective-oocyte-cryopreservation-for-deferred-childbearing
#2
Kara N Goldman, Jamie A Grifo
PURPOSE OF REVIEW: Elective oocyte cryopreservation for deferred childbearing has gained popularity worldwide, commensurate with increased knowledge regarding age-related fertility decline. The purpose of this review is to summarize recent data regarding trends in delayed childbearing, review recent findings surrounding age-related fertility decline, acknowledge significant gaps in knowledge among patients and providers regarding fertility decline and review outcomes following elective oocyte cryopreservation...
December 2016: Current Opinion in Endocrinology, Diabetes, and Obesity
https://www.readbyqxmd.com/read/27649578/aspiration-of-immature-oocytes-during-cesarean-section-for-fertility-preservation
#3
Avi Ben-Haroush, Ronit Abir, Onit Sapir, Roni Garor, Benjamin Fisch
BACKGROUND: In vitro maturation of immature oocytes is an important technology for selected clinical indications. We previously described a pregnant woman with a history of renal transplantation who underwent oocyte aspiration during cesarean section (CS) for fertility preservation and future surrogacy. CASE: A 27-year-old pregnant woman was diagnosed with neck rhabdomyosarcoma at 37 weeks' gestation. CS was performed with direct aspiration of small follicles from one ovary and oophorectomy of the other...
September 21, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27639996/re-implantation-of-cryopreserved-ovarian-cortex-resulting-in-restoration-of-ovarian-function-natural-conception-and-successful-pregnancy-after-haematopoietic-stem-cell-transplantation-for-wilms-tumour
#4
C E Dunlop, B M Brady, M McLaughlin, E E Telfer, J White, F Cowie, S Zahra, W H B Wallace, R A Anderson
With the improvement of long-term cancer survival rates, growing numbers of female survivors are suffering from treatment-related premature ovarian insufficiency (POI). Although pre-treatment embryo and oocyte storage are effective fertility preservation strategies, they are not possible for pre-pubertal girls or women who cannot delay treatment. In these cases, the only available treatment option is ovarian cortex cryopreservation and subsequent re-implantation. A 32-year-old woman had ovarian cortex cryopreserved 10 years previously before commencing high-dose chemotherapy and undergoing a haematopoietic stem cell transplant for recurrent adult Wilms tumour, which resulted in POI...
September 17, 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27609984/the-effect-of-an-immediate-frozen-embryo-transfer-following-a-freeze-all-protocol-a-retrospective-analysis-from-two-centres
#5
Samuel Santos-Ribeiro, Nikolaos P Polyzos, Vuong Thi Ngoc Lan, Johannie Siffain, Shari Mackens, Lisbet Van Landuyt, Herman Tournaye, Christophe Blockeel
STUDY QUESTION: Does the timing of the first frozen embryo transfer (FET) after gonadotropin-releasing hormone (GnRH) agonist triggering with the elective cryopreservation of all embryos affect pregnancy outcome? SUMMARY ANSWER: FETs performed immediately after a freeze-all cycle did not vary significantly from delayed FETs in terms of pregnancy rates. WHAT IS KNOWN ALREADY: As interest in, and use of, the freeze-all strategy expands in the field of reproductive medicine, the optimal timing to perform the subsequent FET has become increasingly important...
November 2016: Human Reproduction
https://www.readbyqxmd.com/read/27584608/are-there-optimal-numbers-of-oocytes-spermatozoa-and-embryos-in-assisted-reproduction
#6
REVIEW
Tanya Milachich, Atanas Shterev
The aim of this overview is to discuss the current information about the search for the optimum yield of gametes in assisted reproduction, as one of the major pillars of IVF success. The first topic is focused on the number of male gametes and the possible impact of some genetic traits on these parameters. The number of spermatozoa did not seem to be crucial when there is no severe male factor of infertility. Genetic testing prior to using those sperm cells is very important. Different methods were applied in order to elect the "best" spermatozoa according to specific indications...
2016: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/27473351/public-support-in-the-united-states-for-elective-oocyte-cryopreservation
#7
Erin I Lewis, Stacey A Missmer, Leslie V Farland, Elizabeth S Ginsburg
OBJECTIVE: To determine whether public support for oocyte cryopreservation (OC) exists and if support varies by demographic factors. DESIGN: Cross-sectional electronic survey. SETTING: Not applicable. PATIENT(S): A nationally representative sample based on age, sex, and race of 1,064 people in the United States recruited by the company SurveyMonkey. INTERVENTIONS(S): Completion of an online questionnaire...
October 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27416834/factors-predicting-double-embryo-implantation-following-double-embryo-transfer-in-assisted-reproductive-technology-implications-for-elective-single-embryo-transfer
#8
Caitlin Martin, Jeani Chang, Sheree Boulet, Denise J Jamieson, Dmitry Kissin
PURPOSE: The aim of this study was to identify factors associated with double embryo implantation following double embryo transfer (DET) during assisted reproductive technology (ART) procedures and to evaluate the implications of findings in selecting candidates for elective single embryo transfer (eSET). METHODS: Factors predicting double embryo implantation, defined as embryo transfers with two or more heartbeats on 6-week ultrasound following DET, were assessed using the US National ART Surveillance System data from 2000 to 2012 (n = 1,793,067 fresh, autologous transfers)...
October 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27114051/comparison-of-ovarian-stimulation-response-in-patients-with-breast-cancer-undergoing-ovarian-stimulation-with-letrozole-and-gonadotropins-to-patients-undergoing-ovarian-stimulation-with-gonadotropins-alone-for-elective-cryopreservation-of-oocytes%C3%A2
#9
Nigel Pereira, Kolbe Hancock, Christina N Cordeiro, Jovana P Lekovich, Glenn L Schattman, Zev Rosenwaks
The primary objective of this study is to compare the oocyte yield in breast cancer patients undergoing controlled ovarian stimulation (COS) using letrozole and gonadotropins with patients undergoing COS with standard gonadotropins for elective cryopreservation of oocytes. Odds ratios (OR) for the number of mature oocytes were estimated. Pregnancy outcomes for breast cancer patients undergoing frozen-thawed 2-PN embryo transfers (FETs) after oncologic treatment were also noted. 220 and 451 cycles were identified in the breast cancer and the elective cryopreservation groups, respectively...
April 26, 2016: Gynecological Endocrinology
https://www.readbyqxmd.com/read/27031375/why-all-women-should-freeze-their-eggs
#10
Ana Cobo, Juan Antonio García-Velasco
PURPOSE OF REVIEW: The use of oocyte cryopreservation via vitrification has increased lately, becoming a common strategy in many IVF centers. This review summarizes the current state of oocyte vitrification, by analyzing the most recent reports on its use in IVF as part of infertile treatment and its contribution to elective fertility preservation (EFP). RECENT FINDINGS: Oocyte vitrification has become helpful for managing different clinical situations currently providing similar results to fresh oocytes...
June 2016: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27006004/oocyte-cryopreservation-where-are-we-now
#11
REVIEW
Catrin E Argyle, Joyce C Harper, Melanie C Davies
INTRODUCTION: Since the first live birth from oocyte cryopreservation three decades ago, oocyte cryopreservation has become an important component of ART. Cryopreservation techniques have evolved, leading to higher success rates and the introduction of oocyte cryopreservation into IVF clinics worldwide. Concurrently, there has been an increase in patient demand, especially for so-called 'social egg freezing' that allows women to preserve their fertility in anticipation of age-related fertility decline...
June 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/26997248/factors-associated-with-the-use-of-elective-single-embryo-transfer-and-pregnancy-outcomes-in-the-united-states-2004-2012
#12
Aaron K Styer, Barbara Luke, Wendy Vitek, Mindy S Christianson, Valerie L Baker, Alicia Y Christy, Alex J Polotsky
OBJECTIVE: To evaluate factors associated with elective single-embryo transfer (eSET) utilization and its effect on assisted reproductive technology outcomes in the United States. DESIGN: Historical cohort. SETTING: Not applicable. PATIENT(S): Fresh IVF cycles of women aged 18-37 years using autologous oocytes with either one (SET) or two (double-embryo transfer [DET]) embryos transferred and reported to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System between 2004 and 2012...
July 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/26943918/female-patients-with-lymphoma-demonstrate-diminished-ovarian-reserve-even-before-initiation-of-chemotherapy-when-compared-with-healthy-controls-and-patients-with-other-malignancies
#13
Jovana Lekovich, Alexandre L S Lobel, Joshua D Stewart, Nigel Pereira, Isaac Kligman, Zev Rosenwaks
PURPOSE: The purpose of this study is to investigate if female patients with lymphoma demonstrate diminished ovarian reserve prior to initiation of the lymphoma treatment. METHODS: Sixty-four patients with newly diagnosed lymphoma undergoing controlled ovarian hyperstimulation for fertility preservation were compared with 365 healthy controls undergoing elective oocyte cryopreservation (controlled ovarian hyperstimulation (COH)) and 128 patients with other types of malignancy prompting fertility preservation...
May 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/26803205/gnrh-agonist-trigger-for-the-induction-of-oocyte-maturation-in-gnrh-antagonist-ivf-cycles-a-swot-analysis
#14
REVIEW
Lawrence Engmann, Claudio Benadiva, Peter Humaidan
Gonadotrophin releasing hormone agonist (GnRHa) trigger is effective in the induction of oocyte maturation and prevention of ovarian hyperstimulation syndrome during IVF treatment. This trigger concept, however, results in early corpora lutea demise and consequently luteal phase dysfunction and impaired endometrial receptivity. The aim of this strenghths, weaknesses, opportunities and threats analysis was to summarize the progress made over the past 15 years to optimize ongoing pregnancy rates after GnRHa trigger...
March 2016: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/26789887/cryopreservation-of-oocytes
#15
LETTER
Jennifer P Schneider
No abstract text is available yet for this article.
January 21, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/26789886/cryopreservation-of-oocytes
#16
LETTER
Martha Hickey, Michelle Peate, Richard A Anderson
No abstract text is available yet for this article.
January 21, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/26789885/cryopreservation-of-oocytes-author-replies
#17
LETTER
Glenn L Schattman
No abstract text is available yet for this article.
January 21, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/26677956/knowledge-attitudes-and-intentions-toward-fertility-awareness-and-oocyte-cryopreservation-among-obstetrics-and-gynecology-resident-physicians
#18
L Yu, B Peterson, M C Inhorn, J K Boehm, P Patrizio
STUDY QUESTION: What knowledge, attitudes and intentions do US obstetrics and gynecology (OB/GYN) residents have toward discussing age-related fertility decline and oocyte cryopreservation with their patients? SUMMARY ANSWER: Most OB/GYN residents believe that age-related fertility decline, but not oocyte cryopreservation, should be discussed during well-woman annual exams; furthermore, nearly half of residents overestimated the age at which female fertility markedly declines...
February 2016: Human Reproduction
https://www.readbyqxmd.com/read/26677584/reproductive-outcomes-of-intracytoplasmic-sperm-injection-icsi-in-good-prognosis-patients-who-electively-decided-to-limit-the-number-of-oocytes-used-for-microinjection-a-two-center-comparative-study
#19
MULTICENTER STUDY
Przemysław Ciepiela, Paweł Kuć, Agnieszka Kuczyńska, Anna Kazienko, Rafał Kurzawa, Waldemar Kuczyński
OBJECTIVES: The aim of the study was to compare the outcomes of intracytoplasmic sperm injection/embryo transfer (ICSI/ET) between two IVF centers with similar pregnancy rates and embryo transfer policy but with two different approaches to good-prognosis patients who intentionally chose to limit the number of oocytes used for ICSI. MATERIAL AND METHODS: It was a retrospective two-center comparative study A total of 218 patients after successful retrieval of >10 mature oocytes following ovarian hyperstimulation were included in the study The number of fertilized oocytes used during ICSI/ET was limited to 6 and 10 in 108 and 110 patients of the Centre for Reproductive Medicine KRIOBANK and VitroLive Fertility Clinic, respectively RESULTS: No significant differences in the implantation rate (29...
October 2015: Ginekologia Polska
https://www.readbyqxmd.com/read/26604065/successful-elective-and-medically-indicated-oocyte-vitrification-and-warming-for-autologous-in-vitro-fertilization-with-predicted-birth-probabilities-for-fertility-preservation-according-to-number-of-cryopreserved-oocytes-and-age-at-retrieval
#20
Joseph O Doyle, Kevin S Richter, Joshua Lim, Robert J Stillman, James R Graham, Michael J Tucker
OBJECTIVE: To evaluate a single treatment center's experience with autologous IVF using vitrified and warmed oocytes, including fertilization, embryonic development, pregnancy, and birth outcomes, and to estimate the likelihood of live birth of at least one, two, or three children according to the number of mature oocytes cryopreserved by elective fertility preservation patients. DESIGN: Retrospective cohort study. SETTING: Private practice clinic...
February 2016: Fertility and Sterility
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