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Resting state fmri psychiatric

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https://www.readbyqxmd.com/read/29755332/neurofeedback-and-the-neural-representation-of-self-lessons-from-awake-state-and-sleep
#1
Andreas A Ioannides
Neurofeedback has been around for half a century, but despite some promising results it is not yet widely appreciated. Recently, some of the concerns about neurofeedback have been addressed with functional magnetic resonance imaging and magnetoencephalography adding their contributions to the long history of neurofeedback with electroencephalography. Attempts to address other concerns related to methodological issues with new experiments and meta-analysis of earlier studies, have opened up new questions about its efficacy...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29755313/individualized-functional-parcellation-of-the-human-amygdala-using-a-semi-supervised-clustering-method-a-7t-resting-state-fmri-study
#2
Xianchang Zhang, Hewei Cheng, Zhentao Zuo, Ke Zhou, Fei Cong, Bo Wang, Yan Zhuo, Lin Chen, Rong Xue, Yong Fan
The amygdala plays an important role in emotional functions and its dysfunction is considered to be associated with multiple psychiatric disorders in humans. Cytoarchitectonic mapping has demonstrated that the human amygdala complex comprises several subregions. However, it's difficult to delineate boundaries of these subregions in vivo even if using state of the art high resolution structural MRI. Previous attempts to parcellate this small structure using unsupervised clustering methods based on resting state fMRI data suffered from the low spatial resolution of typical fMRI data, and it remains challenging for the unsupervised methods to define subregions of the amygdala in vivo ...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29724796/gad65-promoter-polymorphism-rs2236418-modulates-harm-avoidance-in-women-via-inhibition-excitation-balance-in-the-rostral-acc
#3
Lejla Colic, Meng Li, Liliana Ramona Demenescu, Shija Li, Iris Müller, Anni Richter, Constanze I Seidenbecher, Oliver Speck, Björn H Schott, Oliver Stork, Martin Walter
Anxiety disorders are common and debilitating conditions with higher prevalence in women. However, factors that predispose women to anxiety phenotypes are not clarified. Here we investigated potential contribution of the single nucleotide polymorphism rs2236418 in GAD2 gene to changes in regional inhibition/excitation balance, anxiety-like traits and related neural activity in both sexes. 105 healthy individuals were examined with high-field (7T) multimodal magnetic resonance imaging (MRI), including resting state fMRI in combination with assessment of GABA and Glutamate (Glu) levels via MR spectroscopy (MRS)...
May 3, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29664902/a-general-prediction-model-for-the-detection-of-adhd-and-autism-using-structural-and-functional-mri
#4
Bhaskar Sen, Neil C Borle, Russell Greiner, Matthew R G Brown
This work presents a novel method for learning a model that can diagnose Attention Deficit Hyperactivity Disorder (ADHD), as well as Autism, using structural texture and functional connectivity features obtained from 3-dimensional structural magnetic resonance imaging (MRI) and 4-dimensional resting-state functional magnetic resonance imaging (fMRI) scans of subjects. We explore a series of three learners: (1) The LeFMS learner first extracts features from the structural MRI images using the texture-based filters produced by a sparse autoencoder...
2018: PloS One
https://www.readbyqxmd.com/read/29572771/brain-functional-connectivity-correlates-of-coping-styles
#5
Emiliano Santarnecchi, Giulia Sprugnoli, Elisa Tatti, Lucia Mencarelli, Francesco Neri, Davide Momi, Giorgio Di Lorenzo, Alvaro Pascual-Leone, Simone Rossi, Alessandro Rossi
Coping abilities represent the individual set of mental and behavioral strategies adopted when facing stress or traumatic experiences. Coping styles related to avoidance have been linked to a disposition to develop psychiatric disorders such as PTSD, anxiety, and major depression, whereas problem-oriented coping skills have been positively correlated with well-being and high quality of life. Even though coping styles constitute an important determinant of resilience and can impact many aspects of everyday living, no study has investigated their brain functional connectivity underpinnings in humans...
March 23, 2018: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29568687/effects-of-gender-digit-ratio-and-menstrual-cycle-on-intrinsic-brain-functional-connectivity-a-whole-brain-voxel-wise-exploratory-study-using-simultaneous-local-and-global-functional-connectivity-mapping
#6
Tomohiro Donishi, Masaki Terada, Yoshiki Kaneoke
Introduction: Gender and sex hormones influence brain function, but their effects on functional network organization within the brain are not yet understood. Methods: We investigated the influence of gender, prenatal sex hormones (estimated by the 2D:4D digit ratio), and the menstrual cycle on the intrinsic functional network organization of the brain (as measured by 3T resting-state functional MRI (rs-fMRI)) using right-handed, age-matched university students (100 males and 100 females)...
January 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29554302/ventral-striatal-d2-3-receptor-availability-is-associated-with-impulsive-choice-behavior-as-well-aslimbic-corticostriatal-connectivity
#7
Rebecca L Barlow, Martin Gorges, Alfie Wearn, Heiko G Niessen, Jan Kassubek, Jeffrey W Dalley, Anton Pekcec
Background: Low dopamine D2/3 receptor availability in the nucleus accumbens (NAcb) shell is associated with highly-impulsive behavior in rats, as measured by premature responses in a cued attentional task. However, it is unclear whether dopamine D2/3 receptor availability in the NAcb is equally linked to intolerance for delayed rewards, a related form of impulsivity. Methods: We investigated the relationship between D2/3 receptor availability in the NAcb and impulsivity in a delay-discounting task (DDT) where animals must choose between immediate small-magnitude rewards and delayed larger-magnitude rewards...
March 15, 2018: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29545739/variability-in-resting-state-network-and-functional-network-connectivity-associated-with-schizophrenia-genetic-risk-a-pilot-study
#8
Jiayu Chen, Barnaly Rashid, Qingbao Yu, Jingyu Liu, Dongdong Lin, Yuhui Du, Jing Sui, Vince D Calhoun
Imaging genetics posits a valuable strategy for elucidating genetic influences on brain abnormalities in psychiatric disorders. However, association analysis between 2D genetic data (subject × genetic variable) and 3D first-level functional magnetic resonance imaging (fMRI) data (subject × voxel × time) has been challenging given the asymmetry in data dimension. A summary feature needs to be derived for the imaging modality to compute inter-modality association at subject level. In this work, we propose to use variability in resting state networks (RSNs) and functional network connectivity (FNC) as potential features for purpose of association analysis...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29516603/evidence-of-subgroups-in-smokers-as-revealed-in-clinical-measures-and-evaluated-by-neuroimaging-data-a-preliminary-study
#9
Xiaoyu Ding, Betty Jo Salmeron, Jamei Wang, Yihong Yang, Elliot A Stein, Thomas J Ross
To date, fractionation of the nicotine addiction phenotype has been limited to that based primarily on characteristics of cigarette use, although it is widely appreciated that a variety of individual factors are associated with tobacco use disorder. Identifying subtypes of tobacco use disorder based on such factors may lead to better understanding of potential treatment targets, individualize treatments and improve outcomes. In this preliminary study, to identify potential subgroups, we applied hierarchical clustering to a broad range of assessments measuring personality, IQ and psychiatric symptoms, as well as various environmental and experiential characteristics from 102 otherwise healthy cigarette smokers...
March 8, 2018: Addiction Biology
https://www.readbyqxmd.com/read/29427365/neural-and-behavioral-correlates-of-negative-self-focused-thought-associated-with-depression
#10
Carissa L Philippi, M Daniela Cornejo, Carlton P Frost, Erin C Walsh, Roxanne M Hoks, Rasmus Birn, Heather C Abercrombie
A central feature of major depression (MDD) is heightened negative self-focused thought (negative-SFT). Neuroscientific research has identified abnormalities in a network of brain regions in MDD, including brain areas associated with SFT such as medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC). To our knowledge no studies have investigated the behavioral and neural correlates of negative-SFT using a sentence completion task in a sample of individuals with varying depression histories and severities...
May 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29414496/changes-in-dynamic-functional-connections-with-aging
#11
Lixia Tian, Qizhuo Li, Chaomurilige Wang, Jian Yu
Despite numerous studies on age-related changes in static functional connections (FCs), the available literature on the changes in dynamic FCs with aging is lacking. This study investigated the changes in dynamic FCs with aging based on resting state fMRI data of 61 healthy adults aged 30-85 years. The time-resolved FCs among 160 pre-defined regions of interest (ROIs) were first estimated using sliding-window correlation. Based on the dynamic FC matrices, we then analyzed the dynamic switches between different FC states using k-means clustering, and correlated age with the dwell time of each FC state across subjects...
May 15, 2018: NeuroImage
https://www.readbyqxmd.com/read/29410385/functional-magnetic-resonance-imaging-evaluation-of-auricular-percutaneous-electrical-neural-field-stimulation-for-fibromyalgia-protocol-for-a-feasibility-study
#12
Melat Gebre, Anna Woodbury, Vitaly Napadow, Venkatagiri Krishnamurthy, Lisa C Krishnamurthy, Roman Sniecinski, Bruce Crosson
BACKGROUND: Fibromyalgia is a chronic pain state that includes widespread musculoskeletal pain, fatigue, psychiatric symptoms, cognitive and sleep disturbances, and multiple somatic symptoms. Current therapies are often insufficient or come with significant risks, and while there is an increasing demand for non-pharmacologic and especially non-opioid pain management such as that offered through complementary and alternative medicine therapies, there is currently insufficient evidence to recommend these therapies...
February 6, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29410078/a-common-brain-network-among-state-trait-and-pathological-anxiety-from-whole-brain-functional-connectivity
#13
Yu Takagi, Yuki Sakai, Yoshinari Abe, Seiji Nishida, Ben J Harrison, Ignacio Martínez-Zalacaín, Carles Soriano-Mas, Jin Narumoto, Saori C Tanaka
Anxiety is one of the most common mental states of humans. Although it drives us to avoid frightening situations and to achieve our goals, it may also impose significant suffering and burden if it becomes extreme. Because we experience anxiety in a variety of forms, previous studies investigated neural substrates of anxiety in a variety of ways. These studies revealed that individuals with high state, trait, or pathological anxiety showed altered neural substrates. However, no studies have directly investigated whether the different dimensions of anxiety share a common neural substrate, despite its theoretical and practical importance...
May 15, 2018: NeuroImage
https://www.readbyqxmd.com/read/29397900/neural-mechanisms-of-early-life-social-stress-as-a-developmental-risk-factor-for-severe-psychiatric-disorders
#14
Jonathan Rochus Reinwald, Robert Becker, Anne Stephanie Mallien, Claudia Falfan-Melgoza, Markus Sack, Christian Clemm von Hohenberg, Urs Braun, Alejandro Cosa Linan, Natalia Gass, Andrei-Nicolae Vasilescu, Fabian Tollens, Philipp Lebhardt, Natascha Pfeiffer, Dragos Inta, Andreas Meyer-Lindenberg, Peter Gass, Alexander Sartorius, Wolfgang Weber-Fahr
BACKGROUND: To explore the domain-general risk factor of early-life social stress in mental illness, rearing rodents in persistent postweaning social isolation has been established as a widely used animal model with translational relevance for neurodevelopmental psychiatric disorders such as schizophrenia. Although changes in resting-state brain connectivity are a transdiagnostic key finding in neurodevelopmental diseases, a characterization of imaging correlates elicited by early-life social stress is lacking...
December 28, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29348136/resting-state-functional-mri-everything-that-nonexperts-have-always-wanted-to-know
#15
REVIEW
H Lv, Z Wang, E Tong, L M Williams, G Zaharchuk, M Zeineh, A N Goldstein-Piekarski, T M Ball, C Liao, M Wintermark
Resting-state fMRI was first described by Biswal et al in 1995 and has since then been widely used in both healthy subjects and patients with various neurologic, neurosurgical, and psychiatric disorders. As opposed to paradigm- or task-based functional MR imaging, resting-state fMRI does not require subjects to perform any specific task. The low-frequency oscillations of the resting-state fMRI signal have been shown to relate to the spontaneous neural activity. There are many ways to analyze resting-state fMRI data...
January 18, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29324369/early-life-social-stress-and-resting-state-functional-connectivity-in-postpartum-rat-anterior-cingulate-circuits
#16
Benjamin C Nephew, Marcelo Febo, Wei Huang, Luis M Colon-Perez, Laurellee Payne, Guillaume L Poirier, Owen Greene, Jean A King
INTRODUCTION: Continued development and refinement of resting state functional connectivity (RSFC) fMRI techniques in both animal and clinical studies has enhanced our comprehension of the adverse effects of stress on psychiatric health. The objective of the current study was to assess both maternal behavior and resting state functional connectivity (RSFC) changes in these animals when they were dams caring for their own young. It was hypothesized that ECSS exposed dams would express depressed maternal care and exhibit similar (same networks), yet different specific changes in RSFC (different individual nuclei) than reported when they were adult females...
March 15, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29306697/current-sleep-disturbance-in-older-people-with-a-lifetime-history-of-depression-is-associated-with-increased-connectivity-in-the-default-mode-network
#17
Andrew C McKinnon, Ian B Hickie, Jan Scott, Shantel L Duffy, Louisa Norrie, Zoe Terpening, Ron R Grunstein, Jim Lagopoulos, Jennifer Batchelor, Simon J G Lewis, James M Shine, Sharon L Naismith
BACKGROUND: The present study investigated Default Mode Network (DMN) functional connectivity in subjects with a lifetime history of major depression, comparing those with and without current sleep disturbance. Controls were included to assess DMN abnormalities specific to depression. METHODS: A total of 93 adults aged 50 years and over were recruited from the Healthy Brain Ageing Clinic at the Brain and Mind Centre, Sydney, Australia. The sample comprised two groups, including 22 controls and 71 participants with a lifetime history of DSM-IV major depression (with depressive episode current or remitted)...
March 15, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29232968/altered-cerebellar-functional-connectivity-in-remitted-bipolar-disorder-a-resting-state-functional-magnetic-resonance-imaging-study
#18
Ying Wang, Shuming Zhong, Guanmao Chen, Tao Liu, Lianping Zhao, Yao Sun, Yanbin Jia, Li Huang
OBJECTIVES: Several recent studies have reported a strong association between the cerebellar structural and functional abnormalities and psychiatric disorders. However, there are no studies to investigate possible changes in cerebellar functional connectivity in bipolar disorder. This study aimed to examine the whole-brain functional connectivity pattern of patients with remitted bipolar disorder II, in particular in the cerebellum. METHODS: A total of 25 patients with remitted bipolar disorder II and 25 controls underwent resting-state functional magnetic resonance imaging and neuropsychological tests...
December 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29222816/shyness-and-trajectories-of-functional-network-connectivity-over-early-adolescence
#19
Chad M Sylvester, Diana J Whalen, Andy C Belden, Shana L Sanchez, Joan L Luby, Deanna M Barch
High shyness during early adolescence is associated with impaired peer relationships and risk for psychiatric disorders. Little is known, however, about the relation between shyness and trajectories of brain development over early adolescence. The current study longitudinally examined trajectories of resting-state functional connectivity (rs-fc) within four brain networks in 147 adolescents. Subjects underwent functional magnetic resonance imaging at three different time points, at average ages 10.5 (range = 7...
December 8, 2017: Child Development
https://www.readbyqxmd.com/read/29196270/eeg-microstates-as-a-tool-for-studying-the-temporal-dynamics-of-whole-brain-neuronal-networks-a-review
#20
REVIEW
Christoph M Michel, Thomas Koenig
The present review discusses a well-established method for characterizing resting-state activity of the human brain using multichannel electroencephalography (EEG). This method involves the examination of electrical microstates in the brain, which are defined as successive short time periods during which the configuration of the scalp potential field remains semi-stable, suggesting quasi-simultaneity of activity among the nodes of large-scale networks. A few prototypic microstates, which occur in a repetitive sequence across time, can be reliably identified across participants...
December 2, 2017: NeuroImage
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