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Clinical OR Medical AND Negligence

Robert W Aldridge, Dominik Zenner, Peter J White, Elizabeth J Williamson, Morris C Muzyamba, Poonam Dhavan, Davide Mosca, H Lucy Thomas, Maeve K Lalor, Ibrahim Abubakar, Andrew C Hayward
BACKGROUND: Tuberculosis elimination in countries with a low incidence of the disease necessitates multiple interventions, including innovations in migrant screening. We examined a cohort of migrants screened for tuberculosis before entry to England, Wales, and Northern Ireland and tracked the development of disease in this group after arrival. METHODS: As part of a pilot pre-entry screening programme for tuberculosis in 15 countries with a high incidence of the disease, the International Organization for Migration screened all applicants for UK visas aged 11 years or older who intended to stay for more than 6 months...
October 10, 2016: Lancet
Neeraj Nagpal
Physicians and Internists in India have tended to brush under the carpet legal issues affecting their profession. Of concern to all Physicians is the judgment in a recent case where the NCDRC has stated that if MD Medicine Physicians write Physician & Cardiologist on their letterhead it is Quackery. What is MD Medicine degree holder in India qualified and trained to treat ? These are issues which need debate and that can only be initiated once we recognize that there is a problem. Either an MD Medicine is a cardiologist or he is not...
February 2016: Journal of the Association of Physicians of India
Jiaul Hoque, Padma Akkapeddi, Chandardhish Ghosh, Divakara S S M Uppu, Jayanta Haldar
Bacterial colonization and subsequent formation of biofilms onto surfaces of medical devices and implants is a major source of nosocomial infections. Most antibacterial coatings to combat infections are either metal-based or non-degradable polymer-based and hence limited by their non-degradability and unpredictable toxicity. Moreover, to combat infections effectively, the coatings are required to display simultaneous antibacterial and antibiofilm activity. Herein we report biocompatible and biodegradable coatings based on organo-soluble quaternary chitin polymers which were immobilized non-covalently onto surfaces as bactericidal paint...
October 6, 2016: ACS Applied Materials & Interfaces
H Tanaka, H Takyu, R Sagisaka, H Ueta, Toru Shirakawa, Tomoya Kinoshi, Hiroyuki Takahashi, Takashi Nakagawa, Syuji Shimazaki, M Ong Eng Hock
OBJECTIVE: To evaluate the time-independent effect of the early administration of epinephrine (EPI) on favorable neurological outcome (as CPC [cerebral performance category] 1-2) at 1 month in patients with out-of-hospital cardiac arrest. MATERIALS AND METHODS: A total of 119 639 witnessed cardiac arrest patients from 2008 to 2012 were eligible for this nationwide, prospective, population-based observational study. Patients were divided into EPI group (n = 20 420) and non-EPI group (n = 99 219)...
August 19, 2016: American Journal of Emergency Medicine
Yifan Zhang, Lingyi He, Jie Wu, Kaikai Wang, Juan Wang, Weimin Dai, Ahu Yuan, Jinhui Wu, Yiqiao Hu
Photodynamic therapy (PDT) is the combination of light and photosensitizer (PS) to kill tumor cells, which has the potential to meet many currently unmet medical needs. However, the whole body distribution and activatability by sunlight of photosensitizers to induce skin photosensitivity have limited the extensive clinic application of PDT. Herein, a novel strategy is presented to overcome these limitations by using a hydrophobic Near-infared (NIR) dye IR-780 iodide (IR780) to induce the self-assembly of albumin-PS conjugates, as a switchable PDT (Switch-PDT) agent...
November 2016: Biomaterials
Cristina M Beltran-Aroca, Eloy Girela-Lopez, Eliseo Collazo-Chao, Manuel Montero-Pérez-Barquero, Maria C Muñoz-Villanueva
BACKGROUND: Respect for confidentiality is important to safeguard the well-being of patients and ensure the confidence of society in the doctor-patient relationship. The aim of our study is to examine real situations in which there has been a breach of confidentiality, by means of direct observation in clinical practice. METHODS: By means of direct observation, our study examines real situations in which there has been a breach of confidentiality in a tertiary hospital...
2016: BMC Medical Ethics
Robert J Wetzel, Laurence B Kempton, Edwin S Lee, Michal Zlowodzki, Todd O McKinley, Walter W Virkus
OBJECTIVES: We hypothesized that negligible surgical material cost variation exists between traumatolgists for treatment of bimalleolar ankle and bicondylar tibial plateau fractures. DESIGN: Retrospective medical record review. SETTING: Academic Level 1 Trauma Center; 2-year period. PATIENTS/PARTICIPANTS: Common Procedure Terminology (CPT) codes for open treatment of bimalleolar ankle and bicondylar tibial plateau fractures identified patients...
August 23, 2016: Journal of Orthopaedic Trauma
Riccardo Giampieri, Angelo Restivo, Valeria Pusceddu, Michela Del Prete, Elena Maccaroni, Alessandro Bittoni, Luca Faloppi, Kalliopi Andrikou, Maristella Bianconi, Francesco Cabras, Rossana Berardi, Luigi Zorcolo, Francesco Scintu, Stefano Cascinu, Mario Scartozzi
BACKGROUND: The potential clinical impact of aspirin use beyond its canonical indications is a novel matter of scientific debate. In patients with metastatic colorectal cancer failing all available options, regorafenib and TAS 102 represent the only chance of treatment. Although effective, these therapeutic options bring along a not-negligible burden in terms of economic costs and toxicity. In this setting, the indication to use aspirin in combination with chemotherapy would potentially represent a medical revolution under the economic and toxicity profile...
August 4, 2016: Clinical Colorectal Cancer
Sataa Sallami, Mohamed Mongi Mighri, Mahmoud Benatta, Hassen Khouni, Sana Abou El Makarim, Mohamed Allouch, Hassen Touinsi
OBJECTIVE: Pre-existing renal lesions (PERL) may interfere with the patho-physiology of trauma, alter the radiographic imaging and influence the therapeutic approach. The aims of this study were to record the PERL found incidentally during blunt renal trauma, to specify the place for effective conservative management and to determin the estimated partial permanent disability (PPD). PATIENTS AND METHODS: The medical records of 14 patients with PERL and blunt renal trauma were reviewed...
March 2016: La Tunisie Médicale
Shashank Pooniya, C Behera, A R Mridha, D N Bhardwaj, Tabin Millo
Ovarian hyperstimulation syndrome is a rare, but potentially life-threatening iatrogenic disorder arising from ovulation induction or ovarian hyperstimulation for assisted reproduction techniques. We report a case of a 26-year-old multiparous woman, an anonymous egg donor, who died a few hours after undergoing a procedure to donate eggs at an in vitro fertilization clinic. Her husband alleged that medical negligence had led to her death. The autopsy confirmed death due to ovarian hyperstimulation syndrome...
August 19, 2016: Medico-legal Journal
Alice Lo, Nanna Christiansen, Husnain Bhatti
AIM: To determine the impact of displacement values on doses in paediatric patients when using parenteral. To assess the option of using average displacement values (DV) in the preparation of parenteral medicines. METHOD: Over 500 Medusa1 monographs were analysed and 42 medicines were identified with a displacement value not indicated as negligible. The following were calculated: the percentage difference in dose if the DV was not taken into account for each drug and brand, the range of percent differences where there was more than one brand for each strength and the percentage difference in dose incurred if an average DV was used...
September 2016: Archives of Disease in Childhood
Benjamin Pradere, Yair Lotan, Morgan Roupret
PURPOSE OF REVIEW: Lynch syndrome is a genetic syndrome that integrates a large spectrum of cancers caused by germline mutations in mismatch repair genes. Its incidence is underestimated due to a lack of systematic screening in the population. Because upper tract urothelial carcinoma is the third-most common cancer associated with the syndrome, urologists should be aware of the diagnostic pathway. RECENT FINDINGS: Lynch syndrome can be positively diagnosed after the three following distinct steps: meeting the clinical criteria, tissue and genetic testing, and familial genetic counseling...
August 16, 2016: Current Opinion in Urology
Francesco Barchiesi, Elena Orsetti, Patrizia Osimani, Carlo Catassi, Fabio Santelli, Esther Manso
BACKGROUND: Although Candida albicans is the most common cause of fungal blood stream infections (BSIs), infections due to Candida species other than C. albicans are rising. Candida parapsilosis complex has emerged as an important fungal pathogen and became one of the main causes of fungemia in specific geographical areas. We analyzed the factors related to outcome of candidemia due to C. parapsilosis in a single tertiary referral hospital over a five-year period. METHODS: A retrospective observational study of all cases of candidemia was carried out at a 980-bedded University Hospital in Italy...
2016: BMC Infectious Diseases
Bahareh Yazdizadeh, Reza Majdzadeh, Leila Janani, Farideh Mohtasham, Sima Nikooee, Abdmohammad Mousavi, Farid Najafi, Maryam Atabakzadeh, Azam Bazrafshan, Morteza Zare, Manoochehr Karami
BACKGROUND: In recent years, Iran has made significant developments in the field of health sciences. However, the question is whether this considerable increase has affected public health. The research budget has always been negligible and unsustainable in developing countries. Hence, using the Payback Framework, we conducted this study to evaluate the impact of health research in Iran. METHODS: By using a cross-sectional method and two-stage stratified cluster sampling, the projects were randomly selected from six medical universities...
2016: Health Research Policy and Systems
Anne L Dalle Ave, David M Shaw, Dale Gardiner
BACKGROUND: The availability of extracorporeal membrane oxygenation (ECMO) assisted cardiopulmonary resuscitation (E-CPR), for use in refractory out-of hospital cardiac arrest (OHCA), is increasing. In parallel, some countries have developed uncontrolled donation after circulatory determination of death (uDCDD) programs using ECMO to preserve organs for transplantation purposes. AIM: When facing a refractory OHCA, how does the medical team choose between initiating ECMO as part of an E-CPR protocol or ECMO as part of a uDCDD protocol? METHODS: To answer these questions we conducted a literature review on E-CPR compared to uDCDD protocols using ECMO and analyzed the raised ethical issues...
July 20, 2016: Resuscitation
Ikumi Ito, Akihiko Ito, Sakae Unezaki
This study investigated the effect of polyvinylpyrrolidone (PVP) on a film containing carboxymethyl cellulose sodium (CMC) as a matrix to improve surface roughness caused by drug recrystallization. Acetaminophen (AA) was used as the model drug. Recrystallization is a problem encountered during the preparation of films that contain high drug doses, making them difficult to take. A film that does not disintegrate for clinical applications requires a smooth surface, moderate strength and elasticity, and a low level of adhesiveness to facilitate taking of the medication...
2016: Drug Discoveries & Therapeutics
Salah E Kassab, Mariam Fida, Ahmed Radwan, Adla B Hassan, Marwan Abu-Hijleh, Brian P O'Connor
CONTEXT: In problem-based learning (PBL), students construct concept maps that integrate different concepts related to the PBL case and are guided by the learning needs generated in small-group tutorials. Although an instrument to measure students' concept maps in PBL programmes has been developed, the psychometric properties of this instrument have not yet been assessed. OBJECTIVES: This study evaluated the generalisability of and sources of variance in medical students' concept map assessment scores in a PBL context...
July 2016: Medical Education
Kelly K Nichols, Jason Bacharach, Edward Holland, Thomas Kislan, Lee Shettle, Orsolya Lunacsek, Barb Lennert, Caroline Burk, Vaishali Patel
PURPOSE: To assess the effect of dry eye disease on work productivity and performance of non-work-related activities, and patients' satisfaction with over-the-counter (OTC) dry eye treatments. METHODS: In this prospective, noninterventional, cross-sectional study, conducted at 10 U.S. optometry/ophthalmology practices, 158 symptomatic dry eye patients naïve to prescription medication underwent standard dry eye diagnostic tests and completed Work Productivity and Activity Impairment (WPAI) and Ocular Surface Disease Index (OSDI) questionnaires...
June 1, 2016: Investigative Ophthalmology & Visual Science
Mansfield Mela, Glen Luther, Thomas G Gutheil
OBJECTIVES: To extract the themes pertaining to prudent psychiatric practice from written court judgments in Canada. METHODS: We searched the medical and legal literature for cases involving civil litigation against Canadian psychiatrist and reviewed all available written judgments. We completed a thematic analysis of the civil actions against psychiatrists as conveyed by those written court judgments. We classified the cases according to the disposal status and the essential lessons from the decisions on standard of care and practice by Canadian psychiatrists...
February 2016: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
Elizabeth Ngo, Nachiket Patel, Krishnaswamy Chandrasekaran, A Jamil Tajik, Timothy E Paterick
Comprehensive, detailed documentation in the medical record is critical to patient care and to a physician when allegations of negligence arise. Physicians, therefore, would be prudent to have a clear understanding of this documentation. It is important to understand who is responsible for documentation, what is important to document, when to document, and how to document. Additionally, it should be understood who owns the medical record, the significance of the transition to the electronic medical record, problems and pitfalls when using the electronic medical record, and how the Health Information Technology for Economic and Clinical Health Act affects healthcare providers and health information technology...
March 2016: Journal of Medical Practice Management: MPM
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