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Clinical OR Medical AND Negligence

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https://www.readbyqxmd.com/read/29196112/long-term-outcomes-and-prognostic-factors-in-patients-with-mild-hemoptysis
#1
Joonsung Choi, Jun Hyun Baik, Chi Hong Kim, So Hyang Song, Sung Kyung Kim, Myeongjong Kim, Sungeun Yun
OBJECTIVE: The aim of this retrospective study was to observe the long-term outcomes of conservative treatment and bronchial artery embolization (BAE) in patients with mild hemoptysis and to analyze the risk factors associated with hemoptysis recurrence. METHODS: Patients with mild hemoptysis from January 2005 to January 2016 were enrolled in this study. The patients' medical records, including smoking history, etiologic diseases, bronchoscopic findings, mortality, BAE information, and follow-up data of recurrent hemoptysis, were reviewed and analyzed...
November 27, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29185542/pimavanserin-a-novel-therapeutic-option-for-parkinson-disease-psychosis
#2
REVIEW
Trevor Hawkins, Brian D Berman
Purpose of review: In April 2016, the Food and Drug Administration (FDA) approved a first-in-class atypical antipsychotic medication called pimavanserin for the treatment of Parkinson disease psychosis (PDP). We aim to inform readers about its indications, effectiveness, and safety profile. Recent findings: Pimavanserin acts as an inverse agonist at serotonin 5-HT2A receptors and has negligible effects on other receptors, thereby avoiding the D2 receptor antagonism that can potentially worsen motor symptoms...
April 2017: Neurology. Clinical Practice
https://www.readbyqxmd.com/read/29152753/the-hospital-otolaryngologist-the-louisiana-state-university-experience
#3
Phillip G Allen, Laura T Hetzler, Daniel W Nuss, Rohan R Walvekar, Gretchen Penton, Elona Sharbaugh
OBJECTIVES/HYPOTHESIS: To describe the implementation and impact of a hospital otolaryngologist in an academic medical center setting. Our hypothesis was that the hospital otolaryngologist would increase productivity of the Louisiana State University (LSU) faculty otolaryngologists and provide more timely access to inpatient otolaryngology services. STUDY DESIGN: Retrospective clinical and administrative database review. METHODS: A comparative database review was performed with data from the year predating the initiation of the hospitalist program (2013) to the first full year after initiation of the program (2014)...
November 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29138537/development-of-novel-ultrashort-antimicrobial-peptide-nanoparticles-with-potent-antimicrobial-and-antibiofilm-activities-against-multidrug-resistant-bacteria
#4
Ammar Almaaytah, Gubran Khalil Mohammed, Ahmad Abualhaijaa, Qosay Al-Balas
Conventional antibiotics are facing strong microbial resistance that has recently reached critical levels. This situation is leading to significantly reduced therapeutic potential of a huge proportion of antimicrobial agents currently used in clinical settings. Antimicrobial peptides (AMPs) could provide the medical community with an alternative strategy to traditional antibiotics for combating microbial resistance. However, the development of AMPs into clinically useful antibiotics is hampered by their relatively low stability, toxicity, and high manufacturing costs...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29136185/cognitive-dysfunction-among-newly-diagnosed-older-patients-with-hematological-malignancy-frequency-clinical-indicators-and-predictors
#5
Sayo Aiki, Toru Okuyama, Koji Sugano, Yosuke Kubota, Fuminobu Imai, Masahiro Nishioka, Yoshinori Ito, Shinsuke Iida, Hirokazu Komatsu, Takashi Ishida, Shigeru Kusumoto, Tatsuo Akechi
Background: Medical staff often overlook or underestimate the presence or severity of cognitive dysfunction. The purpose of this study was to clarify the frequency, clinical indicators and predictors of cognitive dysfunction among newly diagnosed older patients with hematologic malignancy receiving first-line chemotherapy. Methods: Patients aged 65 years or over with a primary diagnosis of malignant lymphoma or multiple myeloma were consecutively recruited. Cognitive dysfunction was evaluated using the Mini-Mental State Examination (MMSE) twice: before starting chemotherapy (T1) and 1 month later (T2)...
November 10, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29108867/medicolegal-issues-for-the-respiratory-paediatrician
#6
REVIEW
Ian M Balfour-Lynn
The legal profession depends on expert witnesses, and indeed the first time an English Court relied on an expert medical witness was in the 14th century. Asking a specialist to comment on the standard of professional practice expected in their own specialty was first introduced in a 1767 case [1]. This article draws on 20 years of experience in medicolegal work relating to paediatric respiratory medicine. It highlights some of the legal principles that lie behind an expert opinion and what constitutes clinical negligence...
October 12, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/29083339/reoperation-for-persistent-or-recurrent-secondary-hyperparathyroidism
#7
Alida Abruzzo, Maria Concetta Gioviale, Giuseppe Damiano, Vincenzo Davide Palumbo, Salvatore Buscemi, Giulia Lo Monte, Leonardo Gulotta, Giuseppe Buscemi, Attilio Ignazio Lo Monte
BACKGROUND: Secondary hyperparathyroidism is a common acquired disorder seen in chronic renal failure. Its pathophysiology is mainly due to hyperphosphatemia and vitamin D deficiency and resistance. When medical treatment fails, subtotal and total parathyroidectomy with autotransplantation are the standard procedures, although both are associated with high recurrence rates. METHODS AND RESULTS: 4 patients experienced persistence and 9 relapse. The first 4 were subjected to reoperation after 6 months for the persistence of symptoms due to the finding of a supernumerary adenomatous gland while the remaining patients at the reoperation showed in 5 cases 2 more glands in over thymic position, and 4 an hyperplasia of the residual glandular tissue...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29027632/let-us-talk-about-eggs-professional-resistance-to-elective-egg-vitrification-and-gendered-medical-paternalism
#8
Judit Sándor, Lilla Vicsek, Zsófia Bauer
In this paper, by applying a feminist bioethical perspective, we identify a new form of medical paternalism that still shapes contemporary legal policies on human egg cryopreservation performed without medical reasons. The fear of negligent, careless women who opt to delay their pregnancy for mere convenience is a widely known gender biased stereotype. Nevertheless, the opinions and judgments of medical professionals on this issue have not yet been sufficiently explored by in-depth research. In this essay, therefore, first we look at the broader bioethical, legal, and social aspects of human egg cryopreservation...
October 13, 2017: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/29016595/reporting-of-medical-errors-in-autopsied-cases
#9
Bikash Sah, B N Yadav, Shivendra Jha, Ashok Ayer, Ajay Kumar Yadav
This report describes the cases autopsied at B. P. Koirala Institute of Health Sciences- Nepal, during the period of two years in which the treatment provided falls below the accepted standard practice causing the death of the patient. Postmortem examination provides an opportunity to find out the actual cause of death in which the cause of death is suspicious. Sometimes the cause of death found through postmortem examination is different from the clinical cause of death. The autopsy finding on the cause of death will help doctors even to think about unusual conditions that lead to death and hence apply preventive measures for those unusual conditions...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28976414/adjuvant-stromal-amphotericin-b-injection-for-late-onset-dmek-infection
#10
Elmer Y Tu, Parag A Majmudar
PURPOSE: To report the successful medical management of a late-onset Descemet membrane endothelial keratoplasty (DMEK)-related interface infection. METHODS: A case of DMEK endothelial keratoplasty-related infection treated with intrastromal antifungal injection was identified. The following information was collected: demographic data, surgical indications, donor rim cultures, donor mate outcomes, clinical course, diagnostic tests, and clinical outcome. RESULTS: A DMEK patient developed a single infiltrate approximately 1 month after uncomplicated DMEK...
December 2017: Cornea
https://www.readbyqxmd.com/read/28972384/clinical-care-for-an-aging-population
#11
Elisa M Chávez, Amruta Hendre
Pathologic changes in the oral cavity can portend the presence of systemic diseases and result in poor oral health and tooth loss, which are commonly symbolic of aging. Systemic diseases can have direct and indirect effects on oral health, and, likewise, poor oral health can impact general health and wellbeing. Negligence in oral care results in the accumulation of dental plaque and calculus, which eventually contributes to the onset of dental caries, periodontal disease, halitosis, tooth loss, and, ultimately, diminished oral function...
October 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/28953945/incidence-and-clinical-features-of-the-incidentally-found-vascular-stump-thrombus-during-routine-follow-up-after-oncologic-lung-surgery
#12
Mi Hyoung Moon, Kyongmin Sarah Beck, Young Kyu Moon, Jae Kil Park, Sook Whan Sung
OBJECTIVES: We aimed to evaluate the incidence and clinical features of vascular stump thrombus after oncologic lung surgery. METHODS: A retrospective analysis of records from our institutional database dated between 2009 and 2016 was performed. Data regarding demographics, clinical presentation, medication use, operative findings, pathology, and radiologic findings were retrieved. RESULTS: The study cohort consisted of 648 oncologic surgeries for primary lung cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28939735/the-elusive-standard-of-care
#13
Brian K Cooke, Elizabeth Worsham, Gary M Reisfield
In medical negligence cases, the forensic expert must explain to a trier of fact what a defendant physician should have done, or not done, in a specific set of circumstances and whether the physician's conduct constitutes a breach of duty. The parameters of the duty are delineated by the standard of care. Many facets of the standard of care have been well explored in the literature, but gaps remain in a complete understanding of this concept. We examine the standard of care, its origins, and who determines the prevailing standard, beginning with an overview of the historical roots of the standard of care and, using case law, tracing its evolution from the 19th century through the early 21st century...
September 2017: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/28869432/validation-of-a-computational-knee-joint-model-using-an-alignment-method-for-the-knee-laxity-test-and-computed-tomography
#14
Kyoung-Tak Kang, Sung-Hwan Kim, Juhyun Son, Young Han Lee, Yong-Gon Koh
BACKGROUND: Computational models have been identified as efficient techniques in the clinical decision-making process. However, computational model was validated using published data in most previous studies, and the kinematic validation of such models still remains a challenge. Recently, studies using medical imaging have provided a more accurate visualization of knee joint kinematics. OBJECTIVE: The purpose of the present study was to perform kinematic validation for the subject-specific computational knee joint model by comparison with subject's medical imaging under identical laxity condition...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28869382/our-experience-with-the-use-of-40-benzoic-acid-for-necrectomy-in-deep-burns
#15
Z Jelínková, Y Kaloudová, H Řihová, I Suchánek, P Brychta
INTRODUCTION: Chemical necrectomy of deep burns using 40% benzoic acid has been used extensively by the Department of Burns and Reconstructive Surgery at the University Hospital since its establishment in 1982. In spite of definite advantages for the patient and medical staff, hard data concerning benzoic acid absorption through skin necrosis and patient safety was missing. MATERIAL AND METHODS: We examined 22 burn patients in collaboration with the University Hospital Brno, Department of Clinical Biochemistry...
2017: Acta Chirurgiae Plasticae
https://www.readbyqxmd.com/read/28852790/informed-consent-checklists-for-midurethral-slings-a-common-sense-approach
#16
G Alessandro Digesu, Steven Swift, Victoria Handley
INTRODUCTION AND HYPOTHESIS: Following the US Food and Drug Administration's (FDA's) warning about the use of transvaginal mesh to treat pelvic organ prolapse (POP) and the use of single-incision slings to treat incontinence, the number of lawsuits for medical negligence regarding the use of any polypropylene mesh in the vagina has increased tremendously. METHODS: This same FDA document did not question the use of polypropylene midurethral slings and polypropylene for sacrocolpopexies...
November 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28843601/preliminary-evaluation-of-uf-5000-body-fluid-mode-for-automated-cerebrospinal-fluid-cell-counting
#17
Michela Seghezzi, Barbara Manenti, Giulia Previtali, Maria Grazia Alessio, Paola Dominoni, Sabrina Buoro
BACKGROUND: Cellular analysis of cerebrospinal fluid (CSF) provides important diagnostic information in various medical conditions. The aim of this study was to evaluate the application of Sysmex UF-5000 body fluid mode in cytometric analysis of CSF compared to Light Microscopic (LM). METHODS: Eighty-one consecutive CSF samples were analyzed by UF-5000 body fluid mode and by LM. The study also included the evaluation of: limit of Blank (LoB), limit of Detection (LoD), limit of Quantitation (LoQ), carryover and linearity...
October 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28801473/type-2-diabetes-in-the-real-world-the-elusive-nature-of-glycemic-control
#18
Steven V Edelman, William H Polonsky
Despite U.S. Food and Drug Administration (FDA) approval of over 40 new treatment options for type 2 diabetes since 2005, the latest data from the National Health and Nutrition Examination Survey show that the proportion of patients achieving glycated hemoglobin (HbA1c) <7.0% (<53 mmol/mol) remains around 50%, with a negligible decline between the periods 2003-2006 and 2011-2014. The Healthcare Effectiveness Data and Information Set reports even more alarming rates, with only about 40% and 30% of patients achieving HbA1c <7...
August 11, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28792819/clinical-negligence-litigation-balancing-the-interests
#19
John Tingle
John Tingle, Reader in Health Law at Nottingham Trent University, discusses a recent report by the Medical Protection Society on the need to control the costs of clinical negligence litigation.
August 10, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28780202/tailor-made-ge-doped-silica-glass-for-clinical-diagnostic-x-ray-dosimetry
#20
Amjad Alyahyawi, T Jupp, M Alkhorayef, D A Bradley
In the modern clinical practice of diagnostic radiology there is a growing demand for radiation dosimetry, it also being recognized that with increasing use of X-ray examinations additional population dose will result, accompanied by an additional albeit low potential for genetic consequences. At the doses typical of diagnostic radiology there is also a low statistical risk for cancer induction; in adhering to best practice, to be also implied is a low but non-negligible potential for deterministic sensitive organ responses, including in regard to the skin and eyes...
July 22, 2017: Applied Radiation and Isotopes
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