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spasmodic dysphonia

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https://www.readbyqxmd.com/read/29132808/bilateral-vocal-fold-medialization-a-treatment-for-abductor-spasmodic-dysphonia
#1
Karuna Dewan, Gerald S Berke
INTRODUCTION: Abductor spasmodic dysphonia, a difficult-to-treat laryngologic condition, is characterized by spasms causing the vocal folds to remain abducted despite efforts to adduct them during phonation. Traditional treatment for abductor spasmodic dysphonia-botulinum toxin injection into the posterior cricoarytenoid muscle-can be both technically challenging and uncomfortable. Due to the difficulty of needle placement, it is often unsuccessful. The purpose of this investigation is to present a previously undescribed treatment for abductor spasmodic dysphonia-bilateral vocal fold medialization...
November 10, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29117296/polygenic-risk-of-spasmodic-dysphonia-is-associated-with-vulnerable-sensorimotor-connectivity
#2
Gregory Garbès Putzel, Giovanni Battistella, Anna F Rumbach, Laurie J Ozelius, Mert R Sabuncu, Kristina Simonyan
Spasmodic dysphonia (SD), or laryngeal dystonia, is an isolated task-specific dystonia of unknown causes and pathophysiology that selectively affects speech production. Using next-generation whole-exome sequencing in SD patients, we computed polygenic risk score from 1804 genetic markers based on a genome-wide association study in another form of similar task-specific focal dystonia, musician's dystonia. We further examined the associations between the polygenic risk score, resting-state functional connectivity abnormalities within the sensorimotor network, and SD clinical characteristics...
November 19, 2016: Cerebral Cortex
https://www.readbyqxmd.com/read/29099066/chemodenervation-of-the-larynx
#3
REVIEW
Rachel Kaye, Andrew Blitzer
Botulinum neurotoxin (BoNT) has existed for thousands of years; however, it was not medically utilized until investigations into its therapeutic use began in sincerity during the late 1970s and 1980s. This, coupled with the reclassification of spasmodic dysphonia as a focal dystonia, led to the use of chemodenervation for this disorder, which has since become a refined technique. Indeed, due to its safety and efficacy, BoNT has been investigated in multiple neurolaryngology disorders, including spasmodic dysphonia, vocal tremor, and muscle tension dysphonia...
November 2, 2017: Toxins
https://www.readbyqxmd.com/read/28983422/speech-language-pathology-evaluation-and-management-of-hyperkinetic-disorders-affecting-speech-and-swallowing-function
#4
REVIEW
Julie M Barkmeier-Kraemer, Heather M Clark
BACKGROUND: Hyperkinetic dysarthria is characterized by abnormal involuntary movements affecting respiratory, phonatory, and articulatory structures impacting speech and deglutition. Speech-language pathologists (SLPs) play an important role in the evaluation and management of dysarthria and dysphagia. This review describes the standard clinical evaluation and treatment approaches by SLPs for addressing impaired speech and deglutition in specific hyperkinetic dysarthria populations. METHODS: A literature review was conducted using the data sources of PubMed, Cochrane Library, and Google Scholar...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28927659/socioeconomic-variables-of-patients-with-spasmodic-dysphonia-a-preliminary-study
#5
Ashley P O'Connell Ferster, Robert T Sataloff, Patricia A Shewokis, Amanda Hu
OBJECTIVES/HYPOTHESIS: To characterize socioeconomic status (SES) variables of spasmodic dysphonia (SD) patients and determine their impact on voice outcomes after treatment with botulinum toxin. STUDY DESIGN: Retrospective review. MATERIALS AND METHODS: SD patients treated with botulinum toxin for the past 10 years (July 2007-July 2017) for whom sufficient SES and outcome data were available were included. Spearman rho nonparametric correlation coefficients were calculated to determine if SES variables were significantly associated with self-perceived vocal quality...
September 15, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28894815/development-of-a-voice-disorder-work-productivity-inventory-utilizing-cognitive-interviewing-technique
#6
John Paul Giliberto, Qiubei Zhu, Tanya K Meyer
OBJECTIVES/HYPOTHESIS: Voice disorders have been shown to impair workplace productivity primarily by reduced efficiency while at work (presenteeism) versus increased days missed (absenteeism). Work productivity measures such as the Work Productivity and Activity Impairment (WPAI) Questionnaire or the World Health Organization Health - Work Performance Questionnaire (HPQ) can be customized to a specific disease but do not fully capture impaired work productivity associated with voice disorders...
December 2016: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/28802787/reliability-and-validity-of-speech-evaluation-in-adductor-spasmodic-dysphonia
#7
Saori Yanagida, Noriko Nishizawa, Ryusaku Hashimoto, Kenji Mizoguchi, Hiromitsu Hatakeyama, Akihiro Homma, Satoshi Fukuda
OBJECTIVES: The aim of this study was to evaluate speech in patients with adductor spasmodic dysphonia (ADSD) by perceptual evaluations and acoustic measures, and to examine the reliability and validity of these measures. METHODS: Twenty-four patients with ADSD and 24 healthy volunteers were included in the study. Speech materials consisted of three sentences constructed from serial voiced syllables to elicit abductor voice breaks. Three otolaryngologists rated the degree of voice symptoms using a visual analog scale (VAS)...
August 9, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28739333/comparison-of-two-multiparameter-acoustic-indices-of-dysphonia-severity-the-acoustic-voice-quality-index-and-cepstral-spectral-index-of-dysphonia
#8
Jeong Min Lee, Nelson Roy, Elizabeth Peterson, Ray M Merrill
OBJECTIVES: The Acoustic Voice Quality Index (AVQI) and the Cepstral Spectral Index of Dysphonia (CSID) are two multiparameter acoustic indices designed to objectively estimate dysphonia severity and track treatment outcomes. This study compared the performance of these two indices using a common corpus of dysphonic speakers. METHOD: Pre- and posttreatment samples of sustained vowel and connected speech were elicited from 112 patients across six diagnostic categories: unilateral vocal fold paralysis (n = 12), adductor spasmodic dysphonia (n = 12), primary muscle tension dysphonia (n = 12), benign vocal fold lesions (n = 12), presbylaryngis (n = 12), and mutational falsetto (n = 12)...
July 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28687381/operative-procedure-of-anterior-commissure-for-type-ii-thyroplasty
#9
Koji Matsushima, Nobuhiko Isshiki, Masahiro Tanabe, Naoto Yoshizaki, Kazuya Otsu, Akira Fukuo, Kentaro Matsuura, Yusuke Watanabe, Kiminori Sato
OBJECTIVE: We reviewed the clinical anatomy of the anterior commissure and examined the effectiveness of a specialized spreader developed for optimal, efficient spreading of the thyroid cartilage in type II thyroplasty. STUDY DESIGN AND METHODS: The present study was a multicenter retrospective study of patients with spasmodic dysphonia who underwent a primary operation either before or after the introduction of a specialized spreader (in 2008 or 2014, respectively)...
July 4, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28669450/pressure-and-flow-comparisons-across-vocal-pathologies
#10
Linda Carroll, Ann Rooney, Thomas J Ow, Melin Tan
OBJECTIVE: The aim of this study was to aid in the distinction among hyperadductive dysphonias by evaluating peak glottal pressure, release burst, and mid and final airflow values across repeated /pa/ syllable trains. METHODS: Sixty subjects were assessed for aerodynamic patterns during onset-offset for the /papapapapa/ task in modal voice. Subject groups included adductory spasmodic dysphonia (AdSD), benign vocal fold lesion, primary muscle tension dysphonia (MTD-1), secondary muscle tension dysphonia with an identifiable primary benign vocal fold lesion (MTD-2), vocal fold paresis or paralysis, and normal controls...
June 29, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28651822/pharyngeal-dystonia-mimicking-spasmodic-dysphonia
#11
Lucy L Shi, C Blake Simpson, Edie R Hapner, Hyder A Jinnah, Michael M Johns
OBJECTIVE: The aim of this study was to describe the presentation of pharyngeal dystonia (PD), which can occur as a focal or segmental dystonia with a primarily pharyngeal involvement for the discussion of treatment methods for controlling consequent symptoms. PD is specific to speech-related tasks. METHODS: A retrospective medical record review of four patients with PD was performed. RESULTS: All patients were initially misdiagnosed with adductor spasmodic dysphonia and failed standard treatment with botulinum toxin type A (BTX)...
June 23, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28543038/central-voice-production-and-pathophysiology-of-spasmodic-dysphonia
#12
REVIEW
Niv Mor, Kristina Simonyan, Andrew Blitzer
OBJECTIVE: Our ability to speak is complex, and the role of the central nervous system in controlling speech production is often overlooked in the field of otolaryngology. In this brief review, we present an integrated overview of speech production with a focus on the role of central nervous system. The role of central control of voice production is then further discussed in relation to the potential pathophysiology of spasmodic dysphonia (SD). DATA SOURCES: Peer-review articles on central laryngeal control and SD were identified from PUBMED search...
May 23, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28492935/employer-reactions-to-adductor-spasmodic-dysphonia-exploring-the-influence-of-symptom-severity-and-disclosure-of-diagnosis-during-a-simulated-telephone-interview
#13
Derek D Isetti, Carolyn R Baylor, Michael I Burns, Tanya L Eadie
Purpose: The purpose of this study was to determine the influence of symptom severity and disclosure of adductor spasmodic dysphonia (ADSD) on the perceptions of human resource personnel members (HRPs) during a simulated phone interview. Method: One female speaker with ADSD was recorded reading an interview script at two time points: (a) pre-BOTOX injection (severe), and (b) post-BOTOX injection (mild). Thirty-two HRPs evaluated the recording in one of the two conditions via a qualitative structured interview...
May 17, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28463639/long-term-evaluation-of-type-2-thyroplasty-with-titanium-bridges-for-adductor-spasmodic-dysphonia
#14
Tetsuji Sanuki, Eiji Yumoto
Objectives Standard treatments of adductor spasmodic dysphonia (AdSD) provide temporary relief of symptoms. Type 2 thyroplasty offers a long-term solution; however, long-term voice outcome data are lacking. The objective of this study was to assess the long-term voice outcomes of type 2 thyroplasty with titanium bridges through use of a validated voice questionnaire. Study Design Case series with chart review. Setting University hospital. Subjects and Methods Forty-seven consecutively enrolled patients with AdSD underwent type 2 thyroplasty with titanium bridges between August 2006 and November 2014...
July 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28396220/does-even-low-grade-dysphonia-warrant-voice-center-referral
#15
Resha S Soni, Barbara Ebersole, Nausheen Jamal
OBJECTIVE: Data regarding the referral of dysphonic patients to specialty voice clinics are limited. The objective of this study is to examine the relationship between low perceptual dysphonia severity and subtle laryngeal findings to discern if this can help guide referral. STUDY DESIGN: This is a retrospective chart review. METHODS: The charts of 94 patients presenting with a primary complaint of hoarseness to a single laryngologist over a 1-year period at a tertiary care, interdisciplinary voice center were analyzed...
April 7, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28366109/reflections-the-value-of-patient-support-groups
#16
Amanda Hu
A patient support group is defined as "a group of people with common experiences and concerns who provide emotional and moral support for one another." Support groups fulfill many functions: educating patients/family, sharing the illness experience, providing strength to its members, raising public awareness, and fundraising. Some research has shown an improvement in quality of life of patients with head and neck cancer who have participated in support groups. A wide variety of support groups are available for otolaryngology patients, ranging from head and neck oncology to tinnitus and spasmodic dysphonia...
April 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28326007/evaluation-of-the-cortical-silent-period-of-the-laryngeal-motor-cortex-in-healthy-individuals
#17
Mo Chen, Rebekah L S Summers, George S Goding, Sharyl Samargia, Christy L Ludlow, Cecília N Prudente, Teresa J Kimberley
Objective: This work aimed to evaluate the cortical silent period (cSP) of the laryngeal motor cortex (LMC) using the bilateral thyroarytenoid (TA) muscles with transcranial magnetic stimulation (TMS). Methods: In 11 healthy participants, fine-wire electromyography (EMG) was used to record bilateral TA muscle responses to single pulse TMS delivered to the LMC in both hemispheres. Peripheral responses to stimulation over the mastoid, where the vagus nerve exits the skull, were collected to verify the central origin of the cortical stimulation responses by comparing the latencies...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28304188/the-effect-of-unilateral-thalamic-deep-brain-stimulation-on-the-vocal-dysfunction-in-a-patient-with-spasmodic-dysphonia-interrogating-cerebellar-and-pallidal-neural-circuits
#18
Anujan Poologaindran, Zurab Ivanishvili, Murray D Morrison, Linda A Rammage, Mini K Sandhu, Nancy E Polyhronopoulos, Christopher R Honey
Spasmodic dysphonia (SD) is a neurological disorder of the voice where a patient's ability to speak is compromised due to involuntary contractions of the intrinsic laryngeal muscles. Since the 1980s, SD has been treated with botulinum toxin A (BTX) injections into the throat. This therapy is limited by the delayed-onset of benefits, wearing-off effects, and repeated injections required every 3 months. In a patient with essential tremor (ET) and coincident SD, the authors set out to quantify the effects of thalamic deep brain stimulation (DBS) on vocal function while investigating the underlying motor thalamic circuitry...
March 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28258685/-analysis-of-phonosurgical-methods-of-treatment-in-spasmodic-dysphonia
#19
REVIEW
Bożena Kosztyła-Hojna, Greta Berger, Maciej Zdrojkowski
Spasmodic dysphonia (SD) is rather a rare voice disorder. It is most often seen in woman aged 40-50. The disease is caused by deep emotional and neurological disorders of extrapyramidal system. Two main clinical forms of SD are distinguished: about 90% of cases - adductor spasmodic dysphonia and abductor spasmodic dysphonia roughly 10%. Conservative therapy does not always yield sufficient effects. Botulinum toxin - type A injections into the thyroarytenoid muscle are also used in therapy. Though results are temporary and reversible...
February 20, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28249075/the-effect-of-information-and-severity-on-perception-of-speakers-with-adductor-spasmodic-dysphonia
#20
Tanya L Eadie, Reyhaneh Rajabzadeh, Derek D Isetti, Martin T Nevdahl, Carolyn R Baylor
Purpose: The purpose of this study was to examine the effect of severity of adductor spasmodic dysphonia (ADSD) and information about it on unfamiliar listeners' attitudes about speakers' personal characteristics, perceived vocal effort, and listener comfort on the basis of ratings of speech recordings. Method: Fifteen women with ADSD and 5 controls provided speech samples. Forty-five unfamiliar listeners were randomized into 3 groups. Listeners in Group 1 received no information, listeners in Group 2 were told that some speakers had voice disorders or had no voice concerns, and listeners in Group 3 were provided diagnostic labels for each speaker and information about ADSD...
May 17, 2017: American Journal of Speech-language Pathology
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