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https://www.readbyqxmd.com/read/29887479/relationship-between-qrs-duration-and-incident-atrial-fibrillation
#1
Stefanie Aeschbacher, Wesley T O'Neal, Philipp Krisai, Laura Loehr, Lin Y Chen, Alvaro Alonso, Elsayed Z Soliman, David Conen
BACKGROUND: QRS duration (QRSd), a measure of ventricular conduction, has been associated with adverse cardiovascular outcomes, but its relationship with incident atrial fibrillation (AF) is poorly understood. METHODS AND RESULTS: This study included 15,314 participants from the Atherosclerosis Risk in Communities (ARIC) study who were free of AF at baseline. QRSd was automatically measured from resting 12-lead electrocardiograms (ECGs) at baseline. Incident AF cases were systematically ascertained using ECGs, hospital discharge diagnoses and death certificates...
September 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29880141/impact-of-acute-administration-of-sodium-oxybate-on-heart-rate-variability-in-children-with-type-1-narcolepsy
#2
Elena Antelmi, Giuseppe Plazzi, Fabio Pizza, Stefano Vandi, Debora Aricò, Raffaele Ferri
BACKGROUND: Currently, cardiovascular measurements in children affected with type 1 narcolepsy (NT1) have never been investigated, and neither have their modulation by the administration of sodium oxybate (SO). METHODS: Twelve drug-naïve NT1 children (four males, eight females) with a mean age of 11 ± 3.16 years underwent a nocturnal polysomnography, at baseline and during the first night of SO administration. Data were contrasted with those recorded in 23 age-matched healthy controls...
July 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29861104/improvement-in-quality-indicators-using-ncdr%C3%A2-registries-first-international-experience
#3
Pedro Gabriel Melo de Barros E Silva, Henrique Barbosa Ribeiro, Renato Delascio Lopes, Thiago Andrade Macedo, Fabio Conejo, Antônio Cláudio do Amaral Baruzzi, Mariana Yumi Okada, Jose Carlos Teixeira Garcia, Marcelo Jamus Rodrigues, Valter Furlan, Expedito E Ribeiro
BACKGROUND: The National Cardiovascular Data Registry (NCDR®) Database is commonly used for quality-improvement initiatives in North America, but little is known about the application of this tool in other regions of the world. METHODS: All consecutive patients admitted due to myocardial infarction (MI) and/or undergoing percutaneous coronary intervention (PCI) from January 2012 until December 2015 in a Brazilian private cardiovascular hospital were included respectively in ACTION REGISTRY®-GWTG™ and CathPCI Registry®...
May 26, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29759542/a-new-qt-interval-correction-formulae-to-adjust-for-increases-in-heart-rate
#4
Simon W Rabkin, Elena Szefer, Darby J S Thompson
OBJECTIVES: This study sought to develop a formula from a large population-based study that best fit the QT-heart rate (HR) relationship independent of the standard mathematical relationships. BACKGROUND: Attempts to adjust or correct for the impact of HR on the QT interval (QTc) have applied various mathematical equations to electrocardiographic (ECG) data rather than allowing the data to determine the form of the relationship. METHODS: A spline correction function was developed using the ECG data from NHANES (National Health and Nutrition Examination Surveys) II and III...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29740891/effects-of-gut-microbiota-and-time-of-treatment-on-tissue-levels-of-green-tea-polyphenols-in-mice
#5
Anna B Liu, Siyao Tao, Mao-Jung Lee, Qi Hu, Xiaofeng Meng, Yong Lin, Chung S Yang
The previous studies have shown that tea polyphenols are metabolized by gut microbiota. This study investigated the effect of gut microbiota on the bioavailability, tissue levels, and degradation of tea polyphenols. Mice were treated with antibiotics (ampicillin/sulfamethoxazole/trimethoprim) in drinking water and the control mice received water for 11 days, and they were given an AIN93M diet enriched with 0.32% of Polyphenon E. The levels of catechins and their metabolites (if present) in the serum, liver, urine, and fecal samples were determined by high-performance liquid chromatography...
May 8, 2018: BioFactors
https://www.readbyqxmd.com/read/29709876/chronic-vagus-nerve-stimulation-reverses-heart-rhythm-complexity-in-patients-with-drug-resistant-epilepsy-an-assessment-with-multiscale-entropy-analysis
#6
Hongyun Liu, Zhao Yang, Fangang Meng, Lei Huang, Wei Qu, Hongwei Hao, Jianguo Zhang, Luming Li
OBJECTIVE: Vagus nerve stimulation (VNS) is an adjunctive treatment in drug-resistant epilepsy. The alterations in heart rate dynamics through VNS are not well understood. This study aimed to determine changes in heart rhythm complexity in association with VNS and to relate the findings to the outcome of VNS treatment in patients with drug-resistant epilepsy. METHODS: We prospectively analyzed 32 patients with drug-resistant epilepsy, who underwent VNS implantation, and 32 age- and sex-matched healthy control subjects...
April 26, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29680416/electrocardiographic-variables-in-children-with-syndromic-craniosynostosis-and-primary-snoring-to-mild-obstructive-sleep-apnea-significance-of-identifying-respiratory-arrhythmia-during-sleep
#7
Ellaha Kakar, Linda J A Corel, Robert C Tasker, Robbin de Goederen, Eppo B Wolvius, Irene M J Mathijssen, Koen F M Joosten
BACKGROUND: In the spectrum of children with symptomatic sleep disordered breathing (SDB), some individuals - such as those with upper airway resistance syndrome (UARS) - do not have abnormalities on polysomnography (PSG). In this study we have assessed whether assessment of respiratory arrhythmia (RA) and heart rate variability (HRV) analysis helps in management of children with syndromic craniosynostosis and none-to-mild obstructive sleep apnea (OSA). METHODS: Prospective cohort study in children aged 1-18 years old with syndromic craniosynostosis...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29663176/serum-magnesium-and-risk-of-incident-heart-failure-in-older-men-the-british-regional-heart-study
#8
Sasiwarang Goya Wannamethee, Olia Papacosta, Lucy Lennon, Peter H Whincup
To examine the association between serum magnesium and incident heart failure (HF) in older men and investigate potential pathways including cardiac function, inflammation and lung function. Prospective study of 3523 men aged 60-79 years with no prevalent HF or myocardial infarction followed up for a mean period of 15 years, during which 268 incident HF cases were ascertained. Serum magnesium was inversely associated with many CVD risk factors including prevalent atrial fibrillation, lung function (FEV1 ) and markers of inflammation (IL-6), endothelial dysfunction (vWF) and cardiac dysfunction [NT-proBNP and cardiac troponin T (cTnT)]...
April 17, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29622458/usefulness-of-a-clinical-risk-score-to-predict-the-response-to-cardiac-resynchronization-therapy
#9
Rui Providencia, Eloi Marijon, Sergio Barra, Christian Reitan, Alexander Breitenstein, Pascal Defaye, Nikolaos Papageorgiou, Rudolph Duehmke, Stephan Winnik, Richard Ang, Didier Klug, Daniel Gras, Tardu Oezkartal, Oliver R Segal, Jean-Claude Deharo, Christophe Leclercq, Pier D Lambiase, Laurent Fauchier, Pierre Bordachar, Jan Steffel, Nicolas Sadoul, Olivier Piot, Rasmus Borgquist, Sharad Agarwal, Anthony Chow, Serge Boveda
BACKGROUND: Almost 1/3 of heart failure patients fail to respond to cardiac resynchronization therapy (CRT). A simple clinical score to predict who these patients are at the moment of referral or at time of implant may be of importance for early optimization of their management. METHODS: Observational study. A risk score was derived from factors associated to CRT response. The derivation cohort was composed of 1301 patients implanted with a CRT defibrillator in a multi-center French cohort-study...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29605590/measurement-of-fat-fraction-in-the-human-thymus-by-localized-nmr-and-three-point-dixon-mri-techniques
#10
Kenneth W Fishbein, Sokratis K Makrogiannis, Vanessa A Lukas, Marilyn Okine, Ramona Ramachandran, Luigi Ferrucci, Josephine M Egan, Chee W Chia, Richard G Spencer
PURPOSE: To develop a protocol to non-invasively measure and map fat fraction, fat/(fat+water), as a function of age in the adult thymus for future studies monitoring the effects of interventions aimed at promoting thymic rejuvenation and preservation of immunity in older adults. MATERIALS AND METHODS: Three-dimensional spoiled gradient echo 3T MRI with 3-point Dixon fat-water separation was performed at full inspiration for thymus conspicuity in 36 volunteers 19 to 56 years old...
July 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29581199/is-exposure-to-ionising-radiation-associated-with-childhood-cardiac-arrhythmia-in-the-russian-territories-contaminated-by-the-chernobyl-fallout-a-cross-sectional-population-based-study
#11
Jean-Rene Jourdain, Geraldine Landon, Enora Clero, Vladimir Doroshchenko, Aleksandr Silenok, Irina Kurnosova, Andrei Butsenin, Isabelle Denjoy, Didier Franck, Jean-Pierre Heuze, Patrick Gourmelon
OBJECTIVE: To investigate childhood cardiac arrhythmia and chronic exposure to caesium-137 (137 Cs) resulting from the Chernobyl accident. DESIGN: Prospective cross-sectional study using exposed/unexposed design conducted in the Bryansk region from May 2009 to May 2013 on children selected on the basis of 137 Cs soil deposition: control territories ([137 Cs]<37 kBq per square metre, where children were considered as unexposed) and contaminated territories ([137 Cs]>555 kBq per square metre, where children were considered as exposed)...
March 25, 2018: BMJ Open
https://www.readbyqxmd.com/read/29558433/an-energy-efficient-algorithm-for-wearable-electrocardiogram-signal-processing-in-ubiquitous-healthcare-applications
#12
Ali Hassan Sodhro, Arun Kumar Sangaiah, Gul Hassan Sodhro, Sonia Lohano, Sandeep Pirbhulal
Rapid progress and emerging trends in miniaturized medical devices have enabled the un-obtrusive monitoring of physiological signals and daily activities of everyone's life in a prominent and pervasive manner. Due to the power-constrained nature of conventional wearable sensor devices during ubiquitous sensing (US), energy-efficiency has become one of the highly demanding and debatable issues in healthcare. This paper develops a single chip-based wearable wireless electrocardiogram (ECG) monitoring system by adopting analog front end (AFE) chip model ADS1292R from Texas Instruments...
March 20, 2018: Sensors
https://www.readbyqxmd.com/read/29542414/clinical-presentation-quality-of-care-risk-factors-and-outcomes-in-women-with-acute-st-elevation-myocardial-infarction-stemi-an-observational-report-from-six-middle-eastern-countries
#13
Abdulla Shehab, Khalid F AlHabib, Akshaya Srikanth Bhagavathula, Ahmad Hersi, Hussam Alfaleh, Mostafa Q Alshamiri, Anhar Ullah, Khadim Sulaiman, Wael Almahmeed, Jassim Al Suwaidi, Alwai A Alsheikh-Ali, Haitham Amin, Mohammed Al Jarallah, Amar M Salam
BACKGROUND: Most of the available literature on ST-Elevated myocardial infarction (STEMI) in women was conducted in the developed world and data from Middle-East countries was limited. AIM: To examine the clinical presentation, patient management, quality of care, risk factors and in-hospital outcomes of women with acute STEMI compared with men using data from a large STEMI registry from the Middle East. METHODS: Data were derived from the third Gulf Registry of Acute Coronary Events (Gulf RACE-3Ps), a prospective, multinational study of adults with acute STEMI from 36 hospitals in 6 Middle-Eastern countries...
March 14, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29505915/the-influence-of-betamethasone-on-fetal-heart-rate-variability-obtained-by-non-invasive-fetal-electrocardiogram-recordings
#14
Kim M J Verdurmen, Guy J J Warmerdam, Carlijn Lempersz, Alexandra D J Hulsenboom, Joris Renckens, Jeanne P Dieleman, Rik Vullings, Judith O E H van Laar, S Guid Oei
BACKGROUND: Betamethasone is widely used to enhance fetal lung maturation in case of threatened preterm labour. Fetal heart rate variability is one of the most important parameters to assess in fetal monitoring, since it is a reliable indicator for fetal distress. AIM: To describe the effect of betamethasone on fetal heart rate variability, by applying spectral analysis on non-invasive fetal electrocardiogram recordings. STUDY DESIGN: Prospective cohort study...
April 2018: Early Human Development
https://www.readbyqxmd.com/read/29503381/the-national-integrated-project-for-prospective-observation-of-non-communicable-disease-and-its-trends-in-the-aged-2010-nippon-data2010-objectives-design-and-population-characteristics
#15
Aya Kadota, Nagako Okuda, Takayoshi Ohkubo, Tomonori Okamura, Nobuo Nishi, Hirotsugu Ueshima, Akira Okayama, Katsuyuki Miura
BACKGROUND: The structure and risk factors for cardiovascular diseases (CVD) in Japan may change because lifestyle, particularly nutrition, socioeconomic status, and medical care, which affect CVD, may markedly change over time. Therefore, a new prospective cohort study on a representative general Japanese population based on national surveys is required. METHODS: In November 2010, the baseline survey of the National Integrated Project for Prospective Observation of Non-communicable Disease and its Trends in the Aged 2010 (NIPPON DATA2010) was performed with the National Health and Nutrition Survey of Japan (NHNS2010) in 300 randomly selected districts throughout Japan...
2018: Journal of Epidemiology
https://www.readbyqxmd.com/read/29501704/effects-of-guanfu-total-base-on-bcl-2-and-bax-expression-and-correlation-with-atrial-fibrillation
#16
Yan Li, Bingxue Song, Chuanjin Xu
OBJECTIVE: This study sought to investigate the effects of Guanfu total base on Bcl-2 and Bax expression and the correlation of Bcl-2 and Bax expression with atrial fibrillation. METHODS: Twenty-four male Sprague-Dawley rats were randomly divided into control, model, and treatment groups (n = 8 each). A combined intravenous injection of CaCl2 (10 mg/mL) and acetylcholine (Ach; 66 μg/mL) was administered to the model and treatment groups for 7 consecutive days to induce atrial fibrillation...
March 6, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29496772/electrocardiographic-correlates-of-acute-allograft-rejection-among-heart-transplant-recipients
#17
Kathleen T Hickey, Robert R Sciacca, Belinda Chen, Barbara J Drew, David Pickham, Erik V Carter, Carmen Castillo, Lynn V Doering
BACKGROUND: Acute allograft rejection appears to be associated with increases in QT/QTc intervals. OBJECTIVES: To determine the relationship between acute allograft rejection and electrocardiogram changes in patients undergoing an orthotopic heart transplant. METHODS: The study population comprised 220 adult patients undergoing heart transplant and enrolled in the NEW HEART study. Electrocardiograms obtained within 72 hours of endomyocardial biopsy were analyzed; electrocardiograms obtained fewer than 10 days after transplant surgery were excluded...
March 2018: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/29480582/nt-probnp-is-associated-with-mortality-and-adverse-cardiac-events-in-patients-with-atrial-fibrillation-presenting-to-the-emergency-department
#18
Marijn J Holl, Ewout J van den Bos, Ron T van Domburg, Michael A Fouraux, Marcel J Kofflard
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia in the emergency department. The CHA2 DS2 -VASc score helps to predict thromboembolic risk; however, the rate of other adverse cardiac events is more difficult to predict. HYPOTHESIS: The biomarker N-terminal pro-brain natriuretic peptide (NT-proBNP) has prognostic value in patients presenting to the emergency department with AF. METHODS: During a 1.5-year period, a prospective study was performed in consecutive patients presenting to the emergency department with AF on the presenting electrocardiogram...
March 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29459303/the-human-skin-as-a-sub-thz-receiver-does-5g-pose-a-danger-to-it-or-not
#19
Noa Betzalel, Paul Ben Ishai, Yuri Feldman
In the interaction of microwave radiation and human beings, the skin is traditionally considered as just an absorbing sponge stratum filled with water. In previous works, we showed that this view is flawed when we demonstrated that the coiled portion of the sweat duct in upper skin layer is regarded as a helical antenna in the sub-THz band. Experimentally we showed that the reflectance of the human skin in the sub-THz region depends on the intensity of perspiration, i.e. sweat duct's conductivity, and correlates with levels of human stress (physical, mental and emotional)...
May 2018: Environmental Research
https://www.readbyqxmd.com/read/29438471/severity-of-chagasic-cardiomyopathy-is-associated-with-response-to-a-novel-rapid-diagnostic-test-for-trypanosoma-cruzi-tcii-v-vi
#20
Tapan Bhattacharyya, Louisa A Messenger, Caryn Bern, Pascal Mertens, Quentin Gilleman, Nicolas Zeippen, Bruno C Bremer Hinckel, Niamh Murphy, Robert H Gilman, Michael A Miles
Background: Trypanosoma cruzi causes Chagas disease in the Americas. Outcome of infection ranges from lifelong asymptomatic status to severe disease. Understanding how history of T. cruzi lineage (TcI-TcVI) infection relates to clinical prognosis is challenging. We previously described peptide-based lineage-specific ELISA with Trypomastigote Small Surface Antigen (TSSA). Methods: A novel rapid diagnostic test (Chagas Sero K-SeT) incorporating a peptide corresponding to the TSSA-II/V/VI common epitope was developed, and validated by comparison with ELISA...
February 9, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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