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Affective neuroscience

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https://www.readbyqxmd.com/read/29026256/jaak-panksepp-pioneer-of-affective-neuroscience
#1
Brendan M Walker
No abstract text is available yet for this article.
November 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29022840/irritable-temperament-and-lifetime-psychotic-symptoms-as-predictors-of-anxiety-symptoms-in-bipolar-disorder
#2
Gianluca Serafini, Pierre A Geoffroy, Andrea Aguglia, Giulia Adavastro, Giovanna Canepa, Maurizio Pompili, Mario Amore
PURPOSE: Affective temperaments, hopelessness, alexithymia, and anxiety/agitation symptoms may play a significant role in the psychopathological characteristics of bipolar disorder (BD). Here, we aimed to investigate the eventual association between the mentioned explanatory variables and anxiety/agitation symptoms in BD. MATERIALS AND METHODS: We recruited at the Section of Psychiatry, Department of Neuroscience, University of Genoa (Italy), 92 BD inpatients having a mean age of 52 (±13...
October 12, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29017626/case-series-of-mild-behavioral-impairment-toward-an-understanding-of-the-early-stages-of-neurodegenerative-diseases-affecting-behavior-and-cognition
#3
Alicja Cieslak, Eric E Smith, John Lysack, Zahinoor Ismail
Mild behavioral impairment (MBI) is characterized by later life acquired, sustained, and impactful neuropsychiatric symptoms (NPS) of any severity that cannot be better accounted for by other formal medical and psychiatric nosology. MBI is an "at risk" state for incident cognitive decline and dementia, and for some, MBI is the index manifestation of neurodegeneration, observed in advance of cognitive impairment. Initially described in Frontotemporal Dementia (FTD), MBI evolved to describe a preclinical stage of all cause dementia, and has been operationalized in the International Society to Advance Alzheimer's Research and Treatment-Alzheimer's Association (ISTAART-AA) proposed research diagnostic criteria...
October 11, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29017430/characterizing-neurocognitive-late-effects-in-childhood-leukemia-survivors-using-a-combination-of-neuropsychological-and-cognitive-neuroscience-measures
#4
Ellen Van Der Plas, Lauren Erdman, Brian J Nieman, Rosanna Weksberg, Darci T Butcher, Deborah L O'connor, Susanne Aufreiter, Johann Hitzler, Sharon L Guger, Russell J Schachar, Shinya Ito, Brenda J Spiegler
Knowledge about cognitive late effects in survivors of childhood acute lymphoblastic leukemia (ALL) is largely based on standardized neuropsychological measures and parent reports. To examine whether cognitive neuroscience paradigms provided additional insights into neurocognitive and behavioral late effects in ALL survivors, we assessed cognition and behavior using a selection of cognitive neuroscience tasks and standardized measures probing domains previously demonstrated to be affected by chemotherapy. 130 ALL survivors and 158 control subjects, between 8 and 18 years old at time of testing, completed the n-back (working memory) and stop-signal (response inhibition) tasks...
October 10, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/29016167/beyond-happiness-building-a-science-of-discrete-positive-emotions
#5
Michelle N Shiota, Belinda Campos, Christopher Oveis, Matthew J Hertenstein, Emiliana Simon-Thomas, Dacher Keltner
While trait positive emotionality and state positive-valence affect have long been the subject of intense study, the importance of differentiating among several "discrete" positive emotions has only recently begun to receive serious attention. In this article, we synthesize existing literature on positive emotion differentiation, proposing that the positive emotions are best described as branches of a "family tree" emerging from a common ancestor mediating adaptive management of fitness-critical resources (e...
October 2017: American Psychologist
https://www.readbyqxmd.com/read/28994010/parsing-the-neural-correlates-of-anxious-apprehension-and-anxious-arousal-in-the-grey-matter-of-healthy-youth
#6
Peter J Castagna, Scott Roye, Matthew Calamia, Joshua Owens-French, Thompson E Davis, Steven G Greening
Neuroscientific and psychological research posits that there are two transdiagnostic facets of anxiety: anxious arousal and anxious apprehension. Though these two facets of anxiety are distinct, they are often subsumed into one domain (e.g., trait anxiety). The primary goal of the current study was to delineate the relationship between anxious arousal and cortical thickness versus the relationship between anxious apprehension and cortical thickness in a sample of typically functioning youth. The secondary aim was to determine where in the brain cortical thickness significantly correlated with both components of anxiety...
October 9, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28992270/neural-activity-during-affect-labeling-predicts-expressive-writing-effects-on-well-being-glm-and-svm-approaches
#7
Negar Memarian, Jared B Torre, Kate E Haltom, Annette L Stanton, Matthew D Lieberman
Affect labeling (putting feelings into words) is a form of incidental emotion regulation that could underpin some benefits of expressive writing (i.e. writing about negative experiences). Here, we show that neural responses during affect labeling predicted changes in psychological and physical well-being outcome measures 3 months later. Furthermore, neural activity of specific frontal regions and amygdala predicted those outcomes as a function of expressive writing. Using supervised learning (support vector machines regression), improvements in four measures of psychological and physical health (physical symptoms, depression, anxiety and life satisfaction) after an expressive writing intervention were predicted with an average of 0...
September 1, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28975039/creative-music-therapy-to-promote-brain-structure-function-and-neurobehavioral-outcomes-in-preterm-infants-a-randomized-controlled-pilot-trial-protocol
#8
Friederike Barbara Haslbeck, Hans-Ulrich Bucher, Dirk Bassler, Cornelia Hagmann
BACKGROUND: Preterm birth is associated with increased risk of neurological impairment and deficits in cognition, motor function, and behavioral problems. Limited studies indicate that multi-sensory experiences support brain development in preterm infants. Music appears to promote neurobiological processes and neuronal learning in the human brain. Creative music therapy (CMT) is an individualized, interactive therapeutic approach based on the theory and methods of Nordoff and Robbins...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28968396/bistability-non-ergodicity-and-inhibition-in-pairwise-maximum-entropy-models
#9
Vahid Rostami, PierGianLuca Porta Mana, Sonja Grün, Moritz Helias
Pairwise maximum-entropy models have been used in neuroscience to predict the activity of neuronal populations, given only the time-averaged correlations of the neuron activities. This paper provides evidence that the pairwise model, applied to experimental recordings, would produce a bimodal distribution for the population-averaged activity, and for some population sizes the second mode would peak at high activities, that experimentally would be equivalent to 90% of the neuron population active within time-windows of few milliseconds...
October 2, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28963037/disruption-of-the-ascending-arousal-system-and-cortical-attention-networks-in-post-stroke-delirium-and-spatial-neglect
#10
REVIEW
Olga Boukrina, A M Barrett
Delirium is an acute attention and cognitive dysfunction, adversely affecting functional outcomes and mortality. As many as half of hospitalized right brain stroke survivors may develop delirium. Further, about 50% of right stroke patients experience spatial neglect, impairing safety and recovery. In this review we explore the brain mechanisms, which may explain the high incidence of delirium and spatial neglect after right-brain stroke. We suggest that brain networks for spatial attention and arousal, composed of ascending projections from the midbrain nuclei and integrating dorsal and ventral cortical and limbic components, may underlie impairments in delirium and spatial neglect...
September 27, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28961124/parallel-stochastic-discrete-event-simulation-of-calcium-dynamics-in-neuron
#11
Mohammad Nazrul Ishlam Patoary, Carl Tropper, Robert A McDougal, Lin Zhongwei, William W Lytton
The intra-cellular calcium signaling pathways of a neuron depends on both biochemical reactions and diffusions. Some quasi-isolated compartments (e.g. spines) are so small and calcium concentrations are so low that one extra molecule diffusing in by chance can make a nontrivial difference in its concentration (percentage-wise). These rare events can affect dynamics discretely in such way that they cannot be evaluated by a deterministic simulation. Stochastic models of such a system provide a more detailed understanding of these systems than existing deterministic models because they capture their behavior at a molecular level...
September 26, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28959219/investigating-behavioral-and-psychophysiological-reactions-to-conflict-related-and-individualized-stimuli-as-potential-correlates-of-repression
#12
Henrik Kessler, Anna Christine Schmidt, Oliver Hildenbrand, Daniela Scharf, Aram Kehyayan, Nikolai Axmacher
Background: Repression is considered as a central defense mechanism in psychodynamic theory. It refers to the process by which "unbearable" mental contents (e.g., those related to internal conflicts) are kept out of consciousness. The process of repression is probably closely related to concepts of emotion regulation derived from a different theoretical background. This relationship is particularly relevant because it relates repression to current research in the affective neurosciences as well as to experimental studies on emotion regulation...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28959198/distributed-neural-processing-predictors-of-multi-dimensional-properties-of-affect
#13
Keith A Bush, Cory S Inman, Stephan Hamann, Clinton D Kilts, G Andrew James
Recent evidence suggests that emotions have a distributed neural representation, which has significant implications for our understanding of the mechanisms underlying emotion regulation and dysregulation as well as the potential targets available for neuromodulation-based emotion therapeutics. This work adds to this evidence by testing the distribution of neural representations underlying the affective dimensions of valence and arousal using representational models that vary in both the degree and the nature of their distribution...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28951968/amperometry-methods-for-monitoring-vesicular-quantal-size-and-regulation-of-exocytosis-release
#14
REVIEW
Hoda Fathali, Ann-Sofie Cans
Chemical signaling strength during intercellular communication can be regulated by secretory cells through controlling the amount of signaling molecules that are released from a secretory vesicle during the exocytosis process. In addition, the chemical signal can also be influenced by the amount of neurotransmitters that is accumulated and stored inside the secretory vesicle compartment. Here, we present the development of analytical methodologies and cell model systems that have been applied in neuroscience research for gaining better insights into the biophysics and the molecular mechanisms, which are involved in the regulatory aspects of the exocytosis machinery affecting the output signal of chemical transmission at neuronal and neuroendocrine cells...
September 27, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/28951400/suitability-of-a-three-dimensional-model-to-measure-empathy-and-its-relationship-with-social-and-normative-adjustment-in-spanish-adolescents-a-cross-sectional-study
#15
Mauricio Herrera-López, Olga Gómez-Ortiz, Rosario Ortega-Ruiz, Darrick Jolliffe, Eva M Romera
OBJECTIVES: (1) To examine the psychometric properties of the Basic Empathy Scale (BES) with Spanish adolescents, comparing a two and a three-dimensional structure;(2) To analyse the relationship between the three-dimensional empathy and social and normative adjustment in school. DESIGN: Transversal and ex post facto retrospective study. Confirmatory factorial analysis, multifactorial invariance analysis and structural equations models were used. PARTICIPANTS: 747 students (51...
September 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/28950970/cultural-differences-in-the-neural-correlates-of-social-emotional-feelings-an-interdisciplinary-developmental-perspective
#16
REVIEW
Mary Helen Immordino-Yang, Xiao-Fei Yang
Social neuroscience has documented cultural differences in emotional brain functioning. Most recently, these differences have been extended to include cultural effects on the real-time neural correlates of social-emotional feelings. Here we review these findings and use them to illustrate a biopsychosocial framework for studying acculturated social-affective functioning and development. We argue that understanding cultural differences in emotion neurobiology requires probing their social origins and connection with individuals' subjective, lived experiences...
October 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28949821/logical-and-methodological-issues-affecting-genetic-studies-of-humans-reported-in-top-neuroscience-journals
#17
Clara R Grabitz, Katherine S Button, Marcus R Munafò, Dianne F Newbury, Cyril R Pernet, Paul A Thompson, Dorothy V M Bishop
Genetics and neuroscience are two areas of science that pose particular methodological problems because they involve detecting weak signals (i.e., small effects) in noisy data. In recent years, increasing numbers of studies have attempted to bridge these disciplines by looking for genetic factors associated with individual differences in behavior, cognition, and brain structure or function. However, different methodological approaches to guarding against false positives have evolved in the two disciplines. To explore methodological issues affecting neurogenetic studies, we conducted an in-depth analysis of 30 consecutive articles in 12 top neuroscience journals that reported on genetic associations in nonclinical human samples...
September 26, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28932809/aberrant-cortical-activity-in-multiple-gcamp6-expressing-transgenic-mouse-lines
#18
Nicholas A Steinmetz, Christina Buetfering, Jerome Lecoq, Christian R Lee, Andrew J Peters, Elina A K Jacobs, Philip Coen, Douglas R Ollerenshaw, Matthew T Valley, Saskia E J de Vries, Marina Garrett, Jun Zhuang, Peter A Groblewski, Sahar Manavi, Jesse Miles, Casey White, Eric Lee, Fiona Griffin, Joshua D Larkin, Kate Roll, Sissy Cross, Thuyanh V Nguyen, Rachael Larsen, Julie Pendergraft, Tanya Daigle, Bosiljka Tasic, Carol L Thompson, Jack Waters, Shawn Olsen, David J Margolis, Hongkui Zeng, Michael Hausser, Matteo Carandini, Kenneth D Harris
Transgenic mouse lines are invaluable tools for neuroscience but, as with any technique, care must be taken to ensure that the tool itself does not unduly affect the system under study. Here we report aberrant electrical activity, similar to interictal spikes, and accompanying fluorescence events in some genotypes of transgenic mice expressing GCaMP6 genetically encoded calcium sensors. These epileptiform events have been observed particularly, but not exclusively, in mice with Emx1-Cre and Ai93 transgenes, of either sex, across multiple laboratories...
September 2017: ENeuro
https://www.readbyqxmd.com/read/28916140/an-integrative-interdisciplinary-perspective-on-social-dominance-hierarchies
#19
REVIEW
Chen Qu, Romain Ligneul, Jean-Baptiste Van der Henst, Jean-Claude Dreher
In the course of evolution, social dominance has been a strong force shaping the organization of social systems in many species. Individuals with a better ability to represent social dominance relationships and to adapt their behavior accordingly usually achieve better access to resources, hence providing benefits in terms of reproduction, health, and wellbeing. Understanding how and to what extent our brains are affected by social dominance requires interdisciplinary efforts. Here, we integrate findings from social neuroscience, evolutionary biology, and developmental psychology to highlight how social hierarchies are learned and represented in primates...
September 12, 2017: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/28899546/exploring-the-nap-paradox-are-mid-day-sleep-bouts-a-friend-or-foe
#20
REVIEW
Janna Mantua, Rebecca M C Spencer
The mid-day nap, sometimes called a siesta, is a ubiquitous occurrence across the lifespan. It is well established that in addition to reducing sleepiness, mid-day naps offer a variety of benefits: memory consolidation, preparation for subsequent learning, executive functioning enhancement, and a boost in emotional stability. These benefits are present even if a sufficient amount of sleep is obtained during the night prior. However, we present a paradox: in spite of these reported benefits of naps, frequent napping has also been associated with numerous negative outcomes (eg, cognitive decline, hypertension, diabetes), particularly in older populations...
September 2017: Sleep Medicine
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