Xu Chen, Shilei Dong, Yuanfang Shi, Zengguang Wu, Xue Wu, Xiaoyan Zeng, Xinggui Yang, Qi Zhao, Zhenghua Xiao, Qingxue Zhou
Hepatitis C remains a global health problem, especially in poverty-stricken areas. A rapid and sensitive point-of-care (POC) diagnostic tool is critical for the early detection and timely treatment of hepatitis C virus (HCV) infection. Here, for the first time, we reported a novel molecular diagnostic assay, termed reverse transcription multiple cross displacement amplification integrated with a gold-nanoparticle-based lateral flow biosensor (RT-MCDA-AuNPs-LFB), which was developed for rapid, sensitive, specific, and visual identification of HCV...
March 2024: Journal of Medical Virology