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https://www.readbyqxmd.com/read/29338992/subsequent-fertility-pregnancy-and-gynecologic-outcomes-after-fetoscopic-laser-therapy-for-twin-twin-transfusion-syndrome-compared-to-normal-monochorionic-twin-gestations
#1
Simen Vergote, Liesbeth Lewi, Willem Gheysen, Luc de Catte, Roland Devlieger, Jan Deprest
BACKGROUND: An improved survival and quality of life for neonatal survivors after fetoscopic laser therapy (FLC) for twin-twin transfusion syndrome (TTTS) has been reported. However, little is known about the medium-term maternal effects after FLC with respect to reproductive and gynecologic outcomes. OBJECTIVE: To document reproductive, obstetric, gynecologic and psychological outcomes in women who underwent FLC for TTTS. STUDY DESIGN: Monocentric controlled study on consecutive women who underwent FLC for TTTS between 2007 and 2013 at the University Hospitals Leuven (cases; n=198)...
January 12, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29316011/roles-of-venovenous-anastomosis-and-umbilical-cord-insertion-abnormalities-in-birthweight-discordance-in-monochorionic-diamniotic-twin-pregnancies-without-twin-twin-transfusion-syndrome
#2
Hiroko Konno, Takeshi Murakoshi, Akiko Yamashita, Mitsuru Matsushita
AIM: We evaluated risk factors for birthweight discordance in monochorionic diamniotic (MCDA) twin pregnancies without twin-twin transfusion syndrome (TTTS). METHODS: We investigated all MCDA twin placentas injected with colored dye at our institution between 2007 and 2015. We excluded pairs of twins with TTTS, fetal demise, or severe fetal malformation. All pairs of twins were assigned to the discordant group (birthweight discordance ≥ 25%) or the concordant group (birthweight discordance < 25%)...
January 5, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29307066/prevention-of-landfill-pollution-by-multicriteria-spatial-decision-support-systems-mc-sdss-development-implementation-and-case-study
#3
Afshin Khoshand, Ali Hasani Bafrani, Mohammad Zahedipour, Seyed Ahmad Mirbagheri, Majid Ehtehsami
Landfilling of municipal solid waste (MSW) is one of the serious environmental concerns as improper location of MSW landfill site can release the pollutants into the surrounding environment. The process of selecting MSW landfill site is a complicated decision making problem since it is subjected to simultaneous assessment of several environmental criteria, rules, and restrictions besides sociocultural and economic ones. The current study suggests a framework based on Multicriteria spatial decision support systems (MC-SDSS) to select landfill site...
January 6, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29301441/use-of-the-fetal-myocardial-performance-index-in-monochorionic-diamniotic-twin-pregnancy-a-prospective-cohort-and-nested-case-control-study
#4
Amanda Henry, Saranya Gopikrishna, Aditi Mahajan, Jennifer Alphonse, Neama Meriki, Alec W Welsh
AIMS: Assess clinical utility of the fetal Myocardial Performance Index (MPI) in evaluation and management of monochorionic, diamniotic twin (MCDA) pregnancies. METHODS: Prospective cohort of a) initially uncomplicated MCDA b) Complicated MCDA, including twin-twin transfusion syndrome (TTTS), selective intrauterine growth restriction (sIUGR), and liquor and/or growth discordance (L/GD) not meeting TTTS or sIUGR criteria. TTTS and sIUGR were case-control matched...
January 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29298296/a-multi-criteria-decision-analysis-of-management-alternatives-for-anaerobically-digested-kraft-pulp-mill-sludge
#5
Martijn Eikelboom, Alice do Carmo Precci Lopes, Claudio Mudadu Silva, Fábio de Ávila Rodrigues, Antônio José Vinha Zanuncio, José Cola Zanuncio
The Multi-Criteria Decision Analysis (MCDA) procedure was used to compare waste management options for kraft pulp mill sludge following its anaerobic digestion. Anaerobic digestion of sludge is advantageous because it produces biogas that may be used to generate electricity, heat and biofuels. However, adequate management of the digested sludge is essential. Landfill disposal is a non-sustainable waste management alternative. Kraft pulp mill digested sludge applied to land may pose risks to the environment and public health if the sludge has not been properly treated...
2018: PloS One
https://www.readbyqxmd.com/read/29287298/polyhydramnios-affecting-a-recipient-like-twin-risk-of-progression-to-twin-twin-transfusion-syndrome-and-outcomes
#6
Erin E Washburn, Teresa N Sparks, Kristen A Gosnell, Larry Rand, Juan M Gonzalez, Vickie A Feldstein
OBJECTIVE:  The significance of polyhydramnios of one twin in the absence of oligohydramnios of the cotwin in monochorionic diamniotic (MCDA) twin pregnancies (polyhydramnios affecting a recipient-like twin [PART]) is unknown. Our aim is to assess the risk of progression to twin-twin transfusion syndrome (TTTS) with PART, progression to ≥ stage II TTTS, and neonatal survival. STUDY DESIGN:  This study was a retrospective cohort study of MCDA twin pregnancies with PART evaluated at a referral center from 2008 to 2015...
December 29, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29277175/patient-centered-decision-making-lessons-from-multi-criteria-decision-analysis-for-quantifying-patient-preferences
#7
Kevin Marsh, J Jaime Caro, Erica Zaiser, James Heywood, Alaa Hamed
OBJECTIVES: Patient preferences should be a central consideration in healthcare decision making. However, stories of patients challenging regulatory and reimbursement decisions has led to questions on whether patient voices are being considered sufficiently during those decision making processes. This has led some to argue that it is necessary to quantify patient preferences before they can be adequately considered. METHODS: This study considers the lessons from the use of multi-criteria decision analysis (MCDA) for efforts to quantify patient preferences...
December 26, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/29260421/index-based-assessment-of-suitability-of-water-quality-for-irrigation-purpose-under-indian-conditions
#8
Surjeet Singh, N C Ghosh, Suman Gurjar, Gopal Krishan, Sumant Kumar, Preeti Berwal
Agriculture is a major sector in India which contributes around 14% of country's gross domestic product (GDP). Being an agriculture-based country, good quality of water for irrigation has been a prime requisite. Highly growing population and accelerated industrial development are causing anthropogenic pollution to both surface and groundwater on one side and geogenic contamination like arsenic, fluoride, high dissolved solids, sodicity, and iron in groundwater on other side. As a result, ensuring safe water quality for the irrigation has become a major challenge to both the central and state governments...
December 19, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29241899/comparison-of-oral-anticoagulants-for-stroke-prevention-in-nonvalvular-atrial-fibrillation-a-multicriteria-decision-analysis
#9
REVIEW
Tommi Tervonen, Anastasia Ustyugova, Sumitra Sri Bhashyam, Gregory Y H Lip, Paolo Verdecchia, Ryan Kwan, Savion Gropper, Jutta Heinrich-Nols, Kevin Marsh
BACKGROUND: Decision on the most appropriate oral anticoagulation therapy for stroke prevention in patients with nonvalvular atrial fibrillation is difficult because multiple treatment options are available, and these vary in their clinical effects and relevant nonclinical characteristics. OBJECTIVES: To use a multicriteria decision analysis (MCDA) to compare the oral anticoagulants apixaban, dabigatran, edoxaban, rivaroxaban, and vitamin K antagonist (VKAs; specifically warfarin) in patients with nonvalvular atrial fibrillation...
December 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29214575/health-technology-assessment-and-appraisal-of-therapies-for-rare-diseases
#10
Georgi Iskrov, Tsonka Miteva-Katrandzhieva, Rumen Stefanov
Innovative rare disease therapies and health technology assessment (HTA) share a lot of similarities. Both represent cases of interaction of epidemiology and health economics. Both are relatively new topics in public health practice. And both pose a lot of challenges to rare disease stakeholders who are currently looking for tools to support the timely access to innovative treatments while putting budget spending in order. This is why optimisation of assessment and appraisal of new rare disease therapies is a fundamental issue in rare disease health policy...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29210308/using-multi-criteria-decision-analysis-to-appraise-orphan-drugs-a-systematic-review
#11
Carlotta Friedmann, Pierre Levy, Paul Hensel, Mickaël Hiligsmann
Multi-criteria decision analysis (MCDA) could potentially solve current methodological difficulties in the appraisal of orphan drugs. Areas covered: We provide an overview of the existing evidence regarding the use of MCDA in the appraisal of orphan drugs worldwide. Three databases (Pubmed, Embase, Web of Science) were searched for English, French and German literature published between January 2000 and April 2017. Full-text articles were supplemented with conference abstracts. A total of seven articles and six abstracts were identified...
December 20, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/29155937/nanoparticle-based-lateral-flow-biosensor-combined-with-multiple-cross-displacement-amplification-for-rapid-visual-and-sensitive-detection-of-vibrio-cholerae
#12
Yi Wang, Hui Li, Yan Wang, Lu Zhang, Jingyun Zhang, Jianguo Xu, Changyun Ye
Vibrio cholerae (V. cholerae) is an important human pathogen that is responsible for cholera, a severe acute watery diarrhea. In the current study, a multiple cross displacement amplification (MCDA) coupled with amplicon detection by chromatographic lateral flow biosensor (LFB) method (MCDA-LFB) was successfully established and evaluated for identification of V. cholerae. A set of ten primers was designed specifically to recognize ten different regions of the V. cholerae-specific gene ompW. The optimized time and temperature conditions for the MCDA were 30 min at 63˚C...
November 16, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29109010/a-novel-isothermal-amplification-based-method-to-detect-mycobacterium-tuberculosis-complex
#13
Dongxin Liu, Bing Zhao, Xichao Ou, Huiwen Zheng, Aijing Ma, Wencong He, Shengfen Wang, Yang Zhou, Hui Xia, Yang Zheng, Ping Hou, Guangxue He, Yanlin Zhao
Mycobacterium tuberculosis (MTB) is the causative agent of pulmonary tuberculosis. Rapid and accurate diagnosis is crucial to tuberculosis control and prevention. A series of diagnostic methods has been available for MTB detection; however, new rapid, simple and affordable methods are needed. In this study, a multiple cross displacement amplification (MCDA)-based assay was developed to detect the IS6110 gene of the M. tuberculosis complex. Hydroxy naphthol blue (HNB), a colorimetric indicator, was used to detect amplification products...
November 3, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/29091169/-multi-criteria-decision-analysis-for-health-technology-resource-allocation-and-assessment-so-far-and-so-near
#14
Alessandro Gonçalves Campolina, Patrícia Coelho De Soárez, Fábio Vieira do Amaral, Jair Minoro Abe
Multi-criteria decision analysis (MCDA) is an emerging tool that allows the integration of relevant factors for health technology assessment (HTA). This study aims to present a summary of the methodological characteristics of MCDA: definitions, approaches, applications, and implementation stages. A case study was conducted in the São Paulo State Cancer Institute (ICESP) in order to understand the perspectives of decision-makers in the process of drafting a recommendation for the incorporation of technology in the Brazilian Unified National Health System (SUS), through a report by the Brazilian National Commission for the Incorporation of Technologies in the SUS (CONITEC)...
October 26, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29081919/utilization-of-multiple-criteria-decision-analysis-mcda-to-support-healthcare-decision-making-fifarma-2016
#15
Julia I Drake, Juan Carlos Trujillo de Hart, Clara Monleón, Walter Toro, Joice Valentim
Background and objectives:   MCDA is a decision-making tool with increasing use in the healthcare sector, including HTA (Health Technology Assessment). By applying multiple criteria, including innovation, in a comprehensive, structured and explicit manner, MCDA fosters a transparent, participative, consistent decision-making process taking into consideration values of all stakeholders. This paper by FIFARMA (Latin American Federation of Pharmaceutical Industry) proposes the deliberative (partial) MCDA as a more pragmatic, agile approach, especially when newly implemented...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/29073981/applying-multi-criteria-decision-analysis-mcda-simple-scoring-as-an-evidence-based-hta-methodology-for-evaluating-off-patent-pharmaceuticals-opps-in-emerging-markets
#16
Diana Brixner, Nikos Maniadakis, Zoltán Kaló, Shanlian Hu, Jie Shen, Kalman Wijaya
Off-patent pharmaceuticals (OPPs) represent more than 60% of the pharmaceutical market in many emerging countries, where they are frequently evaluated primarily on cost rather than with health technology assessment. OPPs are assumed to be identical to the originators. Branded and unbranded generic versions can, however, vary from the originator in active pharmaceutical ingredients, dosage, consistency formulation, excipients, manufacturing processes, and distribution, for example. These variables can alter the efficacy and safety of the product, negatively impacting both the anticipated cost savings and the population's health...
September 2017: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29073892/multiple-criteria-decision-analysis-in-the-context-of-health-technology-assessment-a-simulation-exercise-on-metastatic-colorectal-cancer-with-multiple-stakeholders-in-the-english-setting
#17
Aris Angelis, Gilberto Montibeller, Daniel Hochhauser, Panos Kanavos
BACKGROUND: Multiple criteria decision analysis (MCDA) has appeared as a methodology to address limitations of economic evaluation in health technology assessment (HTA), however there are limited empirical evidence from real world applications. The aim of this study is to test in practice a recently developed MCDA methodological framework known as Advance Value Framework (AVF) through a proof-of-concept case study engaging multiple stakeholders. METHODS: A multi-attribute value theory methodological process was adopted involving problem structuring, model building, model assessment and model appraisal phases...
October 26, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29056378/use-of-multi-criteria-decision-analysis-to-identify-potentially-dangerous-glacial-lakes
#18
Ioannis Kougkoulos, Simon J Cook, Vincent Jomelli, Leon Clarke, Elias Symeonakis, Jason M Dortch, Laura A Edwards, Myriam Merad
Glacial Lake Outburst Floods (GLOFs) represent a significant threat in deglaciating environments, necessitating the development of GLOF hazard and risk assessment procedures. Here, we outline a Multi-Criteria Decision Analysis (MCDA) approach that can be used to rapidly identify potentially dangerous lakes in regions without existing tailored GLOF risk assessments, where a range of glacial lake types exist, and where field data are sparse or non-existent. Our MCDA model (1) is desk-based and uses freely and widely available data inputs and software, and (2) allows the relative risk posed by a range of glacial lake types to be assessed simultaneously within any region...
October 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29037087/a-label-free-technique-for-accurate-detection-of-nucleic-acid-based-self-avoiding-molecular-recognition-systems-supplemented-multiple-cross-displacement-amplification-and-nanoparticles-based-biosensor
#19
Yi Wang, Yan Wang, Hong Wang, Jianguo Xu, Changyun Ye
Here, we devised a novel isothermal technique on the basis of standard multiple cross-displacement amplification (MCDA), which is assisted with self-avoiding molecular recognition system (SAMRS) components and antarctic thermal-sensitive uracil-DNA-glycosylase enzyme (AUDG), termed AUDG-SAMRS-MCDA. To enable product detection on the dipsticks, we firstly developed an analysis strategy, which did not require the labelled primers or probes, and thus, the analysis system avoids the false-positive results arising from undesired hybridization (between two labelled primers, or the labelled probe and primer)...
October 16, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28976606/the-significance-of-placental-cord-insertion-site-in-twin-pregnancy
#20
Erkan Kalafat, Basky Thilaganathan, Aris Papageorghiou, Amar Bhide, Asma Khalil
OBJECTIVE: The aim of this study was to investigate the association between abnormal cord insertion and the development of the twin-specific complications, including birthweight discordance, selective fetal growth restriction (sFGR) and twin-to-twin transfusion syndrome (TTTS). METHODS: A single-center cohort study of twin pregnancies. Abnormal cord insertion was defined as either marginal (cord attachment site less than 2cm to the nearest margin of the placental disc) or velamentous (when the umbilical cord was attached to the membrane before reaching the placental disc with clear evidence of vessels traversing the membranes to connect with the placental disc), as described in placental pathology reports...
October 4, 2017: Ultrasound in Obstetrics & Gynecology
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