keyword
MENU ▼
Read by QxMD icon Read
search

Never events

keyword
https://www.readbyqxmd.com/read/28732032/individual-and-area-level-characteristics-associated-with-alcohol-related-mortality-among-adult-lithuanian-males-a-multilevel-analysis-based-on-census-linked-data
#1
Pavel Grigoriev, Domantas Jasilionis, Daumantas Stumbrys, Vladislava Stankūnienė, Vladimir M Shkolnikov
BACKGROUND: Although excessive alcohol-related mortality in the post-Soviet countries remains the major public health threat, determinants of this phenomenon are still poorly understood. AIMS: We assess simultaneously individual- and area-level factors associated with an elevated risk of alcohol-related mortality among Lithuanian males aged 30-64. METHODS: Our analysis is based on a census-linked dataset containing information on individual- and area-level characteristics and death events which occurred between March 1st, 2011 and December 31st, 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28728559/effect-of-insulin-therapy-and-dietary-adjustments-on-safety-and-performance-during-simulated-soccer-tests-in-people-with-type-1-diabetes-study-protocol-for-a-randomized-controlled-trial
#2
Javier Calvo-Marín, Gabriel Torrealba-Acosta, Matthew Campbell, Jesse Gaboury, Ajmol Ali, Chih Hao Chen-Ku
BACKGROUND: Despite the reduction in glycemic derangement in patients with type 1 diabetes mellitus (T1D) through dietary and therapeutic adjustments implemented before, during and after continuous exercise, evidence for its effectiveness with intermittent forms of exercise, such as soccer, is still lacking. METHODS/DESIGN: We designed a study protocol for a randomized, crossover, double-blinded, controlled trial, for the evaluation of the effect that a strategy of dietary and therapeutic modifications may have on safety and performance of persons with T1D in soccer training sessions and cognitive testing...
July 20, 2017: Trials
https://www.readbyqxmd.com/read/28719084/defending-a-never-event
#3
John R Shepperd
There are medical mishaps that have been deemed "Never Events" by the Centers for Medicare & Medicaid Services (CMS). This term refers generally to preventable occurrences so egregious that they should never occur. But they do occur. And when they do, litigation often follows. This article focuses on one such Never Event-the operating room fire-with strategies on how to defend it. Information provided in this article was derived from a review of the relevant literature and from the author's personal experience defending lawsuits arising from Never Events, including a jury trial involving a surgeon who was sued for a patient's injuries after a fire erupted in the operating room...
July 2017: Journal of Healthcare Risk Management: the Journal of the American Society for Healthcare Risk Management
https://www.readbyqxmd.com/read/28717911/laparoscopic-compared-to-open-repeat-hepatectomy-for-colorectal-liver-metastases-a-multi-institutional-propensity-matched-analysis-of-short-and-long-term-outcomes
#4
Julie Hallet, Antonio Sa Cunha, Daniel Cherqui, Brice Gayet, Diane Goéré, Philippe Bachellier, Alexis Laurent, David Fuks, Francis Navarro, Patrick Pessaux
INTRODUCTION: While uptake of laparoscopic hepatectomy has improved, evidence on laparoscopic re-hepatectomy (LRH) for colorectal liver metastases (CRLMs) is limited and has never been compared to the open approach. We sought to define outcomes of LRH compared to open re-hepatectomy (ORH). METHODS: Patients undergoing re-hepatectomy for CRLM at 39 institutions (2006-2013) were identified. Primary outcomes were 30-day post-operative overall morbidity, mortality, and length of stay...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28715673/activity-level-dna-evidence-evaluation-on-propositions-addressing-the-actor-or-the-activity
#5
Bas Kokshoorn, Bart J Blankers, Jacob de Zoete, Charles E H Berger
More often than not, the source of DNA traces found at a crime scene is not disputed, but the activity or timing of events that resulted in their transfer is. As a consequence, practitioners are increasingly asked to assign a value to DNA evidence given propositions about activities provided by prosecution and defense counsel. Given that the dispute concerns the nature of the activity that took place or the identity of the actor that carried out the activity, several factors will determine how to formulate the propositions...
July 3, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28713252/effect-of-postural-control-demands-on-early-visual-evoked-potentials-during-a-subjective-visual-vertical-perception-task-in-adolescents-with-idiopathic-scoliosis
#6
Yi-Tzu Chang, Ling-Fu Meng, Chun-Ju Chang, Po-Liang Lai, Chi-Wen Lung, Jen-Suh Chern
Subjective visual vertical (SVV) judgment and standing stability were separately investigated among patients with adolescent idiopathic scoliosis (AIS). Although, one study has investigated the central mechanism of stability control in the AIS population, the relationships between SVV, decreased standing stability, and AIS have never been investigated. Through event-related potentials (ERPs), the present study examined the effect of postural control demands (PDs) on AIS central mechanisms related to SVV judgment and standing stability to elucidate the time-serial stability control process...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28712314/angiogenesis-inhibitors-and-symptomatic-anal-ulcers-in-metastatic-colorectal-cancer-patients
#7
Francesca Bergamo, Sara Lonardi, Beatrice Salmaso, Carmelo Lacognata, Francesca Battaglin, Francesco Cavallin, Luca Saadeh, Sabina Murgioni, Antonino Caruso, Camillo Aliberti, Vittorina Zagonel, Carlo Castoro, Marco Scarpa
BACKGROUND: Angiogenesis inhibitors are a standard first-line treatment for metastatic colorectal cancer. Anal canal pain is a common adverse event, but its cause has never been described. The aim of the study was to evaluate the association between the use of angiogenesis inhibitors and symptomatic anal ulcer development. METHODS: This retrospective cohort study included all 601 consecutive metastatic colorectal cancer patients undergoing first line treatment from January 2010 to June 2016 at the Veneto Institute of Oncology...
July 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28709194/effects-of-communication-burstiness-on-consensus-formation-and-tipping-points-in-social-dynamics
#8
C Doyle, B K Szymanski, G Korniss
Current models for opinion dynamics typically utilize a Poisson process for speaker selection, making the waiting time between events exponentially distributed. Human interaction tends to be bursty though, having higher probabilities of either extremely short waiting times or long periods of silence. To quantify the burstiness effects on the dynamics of social models, we place in competition two groups exhibiting different speakers' waiting-time distributions. These competitions are implemented in the binary naming game and show that the relevant aspect of the waiting-time distribution is the density of the head rather than that of the tail...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28708414/feasibility-and-acceptability-of-qigong-exercise-in-community-dwelling-older-adults-in-the-united-states
#9
Pei-Shiun Chang, M Tish Knobf, Marjorie Funk, Byeongsang Oh
OBJECTIVES: Qigong exercise has been shown to improve physical and psychological well-being in adults with chronic conditions, but little is known about the feasibility and acceptability of engaging in a qigong exercise program in community-dwelling older adults in the United States. The purpose of this study was to explore the feasibility, acceptance, and adherence to an 8-week qigong exercise intervention in community-dwelling American older adults. DESIGN: An exploratory study design...
July 14, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28695528/never-forget-negative-emotional-valence-enhances-recapitulation
#10
Holly J Bowen, Sarah M Kark, Elizabeth A Kensinger
A hallmark feature of episodic memory is that of "mental time travel," whereby an individual feels they have returned to a prior moment in time. Cognitive and behavioral neuroscience methods have revealed a neurobiological counterpart: Successful retrieval often is associated with reactivation of a prior brain state. We review the emerging literature on memory reactivation and recapitulation, and we describe evidence for the effects of emotion on these processes. Based on this review, we propose a new model: Negative Emotional Valence Enhances Recapitulation (NEVER)...
July 10, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28695310/central-aortic-pulse-pressure-thrombogenicity-and-cardiovascular-risk
#11
Gailing Chen, Kevin P Bliden, Rahul Chaudhary, Fang Liu, Himabindu Kaza, Eliano P Navarese, Udaya S Tantry, Paul A Gurbel
High central aortic pulse pressure (CPP) and thrombin-induced platelet-fibrin clot strength (TIP-FCS) have been associated with ischemic outcomes in patients with coronary artery disease in separate studies. But, the ischemic risk associated with these factors has never been analyzed in a single study and their interrelation is unknown. The primary aim of the study was to establish cut points for CPP and TIP-FCS measured at the time of catheterization associated with long term major adverse cardiovascular events...
August 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/28692130/the-index-case-is-not-enough-variation-among-individuals-groups-and-social-networks-modify-bacterial-transmission-dynamics
#12
Carl N Keiser, Noa Pinter-Wollman, Michael J Ziemba, Krishna S Kothamasu, Jonathan N Pruitt
1.The traits of the index case of an infectious disease outbreak, and the circumstances for their etiology, potentially influence the trajectory of transmission dynamics. However, these dynamics likely also depend on the traits of the individuals with whom the index case interacts. 2.We used the social spider Stegodyphus dumicola to test how the traits of the index case, group phenotypic composition, and group size interact to facilitate the transmission of a GFP-labeled cuticular bacterium. We also compared bacterial transmission across experimentally generated "daisy-chain" versus "star" networks of social interactions...
July 10, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28690473/total-knee-arthroplasty-for-knee-osteoarthritis-support-for-a-foregone-conclusion
#13
REVIEW
Michael E Steinhaus, Alexander B Christ, Michael B Cross
Total knee arthroplasty (TKA) is generally accepted as the definitive treatment for advanced knee arthritis after patients fail nonoperative treatments; however, the safety and efficacy of TKA compared to continued nonoperative treatment has never been proven in high-quality, randomized controlled trials. Recently, a 2015 Danish study published a 12-month follow-up on a cohort of patients randomized to either a TKA or continued nonsurgical management for advanced knee osteoarthritis (OA). The authors reported significantly greater improvement in the TKA group in functional outcome scores such as the overall Knee Injury and Osteoarthritis Outcome Score (KOOS4 score), the KOOS subscales, EQ-5D descriptive index, and timed get up-and-go and 20-m walk tests; however, patients in the TKA did suffer significantly more serious adverse events (SAE)...
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28688113/assessing-clinical-probability-of-pulmonary-embolism-prospective-validation-of-the-simplified-geneva-score-in-outpatients
#14
H Robert-Ebadi, K Mostaguir, M M Hovens, M Kare, F Verschuren, P Girard, M V Huisman, F Moustafa, P W Kamphuisen, H R Buller, M Righini, G Le Gal
BACKGROUND: Pretest probability assessment by a clinical prediction rule (CPR) is an important step in the management of patients with suspected pulmonary embolism (PE). A limitation to the use of CPR is that their constitutive variables and corresponding number of points are difficult to memorize. A simplified version of the Geneva score (i.e. attributing one point to each variable) has been proposed but never been prospectively validated. AIMS: Prospective validation of the simplified Geneva score (SGS) and comparison with the previous version of the Geneva score (GS)...
July 8, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28686693/ivermectin-treatment-of-loa-loa-hyper-microfilaraemic-baboons-papio-anubis-assessment-of-microfilarial-loads-haematological-and-biochemical-parameters-and-histopathological-changes-following-treatment
#15
Samuel Wanji, Ebanga-Echi J Eyong, Nicholas Tendongfor, Che J Ngwa, Elive N Esuka, Arnaud J Kengne-Ouafo, Fabrice R Datchoua-Poutcheu, Peter Enyong, Dalen Agnew, Rob R Eversole, Adrian Hopkins, Charles D Mackenzie
BACKGROUND: Individuals with high intensity of Loa loa are at risk of developing serious adverse events (SAEs) post treatment with ivermectin. These SAEs have remained unclear and a programmatic impediment to the advancement of community directed treatment with ivermectin. The pathogenesis of these SAEs following ivermectin has never been investigated experimentally. The Loa/baboon (Papio anubis) model can be used to investigate the pathogenesis of Loa-associated encephalopathy following ivermectin treatment in humans...
July 7, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28685090/a-retrospective-study-of-docetaxel-and-bevacizumab-as-a-second-or-later-line-chemotherapy-for-non-small-cell-lung-cancer
#16
Koichi Kurishima, Hiroko Watanabe, Hiroichi Ishikawa, Hiroaki Satoh, Nobuyuki Hizawa
Comparative results of second- or later-line bevacizumab plus docetaxel and docetaxel alone for patients with NSCLC have never been reported. In order to evaluate the combined effect of bevacizumab and docetaxel as second- or later-line chemotherapy for NSCLC, a retrospective study was performed. Between November 2009 and April 2016, the medical records of all the patients <75 years old who were treated with docetaxel (60 mg/m(2), day1, q3 or 4 weeks) plus bevacizumab (15 mg/kg, day 1, q3 or 4 weeks) as a second- or later-line chemotherapy were reviewed...
July 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28684836/improving-patient-safety-through-a-clinical-audit-spiral-prevention-of-wrong-tooth-extraction-in-orthodontics
#17
H Anwar, D Waring
Introduction With an increasing demand to improve patient safety within the NHS, it is important to ensure that measures are undertaken to continually improve patient care. Wrong site surgery has been defined as a 'never event'. This article highlights the importance of preventing wrong tooth extraction within orthodontics through an audit spiral over five years investigating the accuracy and clarity of orthodontic extraction letters at the University Dental Hospital of Manchester.Aims To examine compliance with the standards for accuracy and clarity of extraction letters and the incidence of wrong tooth extractions, and to increase awareness of the errors that can occur with extraction letters and of the current guidelines...
July 7, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28676214/dna-mismatch-repair-deficiency-in-surgically-resected-lung-adenocarcinoma-microsatellite-instability-analysis-using-the-promega-panel
#18
Kazuya Takamochi, Fumiyuki Takahashi, Yoshiyuki Suehara, Eiichi Sato, Shinji Kohsaka, Takuo Hayashi, Shigehisa Kitano, Toshihide Uneno, Shinya Kojima, Kengo Takeuchi, Hiroyuki Mano, Kenji Suzuki
OBJECTIVES: DNA mismatch repair (MMR) deficiency has recently received increasing attention as a significant biomarker to predict the treatment effect of immune checkpoint inhibitors for various malignant neoplasms. To evaluate MMR status, we analyzed the microsatellite instability (MSI) of lung adenocarcinomas. MATERIALS AND METHODS: Frozen tissues of lung adenocarcinoma and corresponding normal lung were obtained from 341 patients, including 141 with tumors harboring driver gene alterations (50 EGFR gene mutations, 50 KRAS gene mutations, 21 ALK fusions, 10 ROS1 fusions, and 10 RET fusions) and 200 with pan-negative tumors (100 never- or light-smokers and 100 heavy-smokers), who were surgically treated between 2007 and 2015...
August 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28672960/baicalin-promotes-the-viability-of-schwann-cells-in-vitro-by-regulating-neurotrophic-factors
#19
Wenpu Zuo, Huayu Wu, Kun Zhang, Peizhen Lv, Fuben Xu, Weizhe Jiang, Li Zheng, Jinmin Zhao
The proliferation and migration of Schwann cells (SCs) are key events in the process of peripheral nerve repair. This is required to promote the growth of SCs and is a challenge during the treatment of peripheral nerve injury. Baicalin is a natural herb-derived flavonoid compound, which has been reported to possess neuroprotective effects on rats with permanent brain ischemia and neuronal differentiation of neural stem cells. The association of baicalin with neuroprotection leads to the suggestion that baicalin may exert effects on the growth of SCs...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28669794/climate-science-truth-and-democracy
#20
Evelyn Fox Keller
This essay was written almost ten years ago when the urgency of America's failure as a nation to respond to the threats of climate change first came to preoccupy me. Although the essay was never published in full, I circulated it informally in an attempt to provoke a more public engagement among my colleagues in the history, philosophy, and sociology of science. In particular, it was written in almost direct response to Philip Kitcher's own book, Science, Truth and Democracy (2001), in an attempt to clarify what was special about Climate Science in its relation to truth and democracy...
June 29, 2017: Studies in History and Philosophy of Biological and Biomedical Sciences
keyword
keyword
61213
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"