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Qualitative methods

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https://www.readbyqxmd.com/read/28340250/improving-safety-culture-in-hospitals-facilitators-and-barriers-to-implementation-of-systemic-falls-investigative-method-sfim
#1
Aleksandra A Zecevic, Alvin Ho-Ting Li, Charity Ngo, Michelle Halligan, Anita Kothari
Objective: The purpose of this study was to assess the facilitators and barriers to implementation of the Systemic Falls Investigative Method (SFIM) on selected hospital units. Design: A cross-sectional explanatory mixed methods design was used to converge results from a standardized safety culture survey with themes that emerged from interviews and focus groups. Findings were organized by six elements of the Ottawa Model of Research Use framework. Setting: A geriatric rehabilitation unit of an acute care hospital and a neurological unit of a rehabilitation hospital were selected purposefully due to the high frequency of falls...
March 17, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28339697/are-informed-policies-in-place-to-promote-safe-and-usable-ehrs-a-cross-industry-comparison
#2
Erica L Savage, Rollin J Fairbanks, Raj M Ratwani
Objective: Despite federal policies put in place by the Office of the National Coordinator (ONC) to promote safe and usable electronic health record (EHR) products, the usability of EHRs continues to frustrate providers and have patient safety implications. This study sought to compare government policies on usability and safety, and methods of examining compliance to those policies, across 3 federal agencies: the ONC and EHRs, the Federal Aviation Administration (FAA) and avionics, and the Food and Drug Administration (FDA) and medical devices...
February 19, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28339486/a-top-down-manner-based-dcnn-architecture-for-semantic-image-segmentation
#3
Kai Qiao, Jian Chen, Linyuan Wang, Lei Zeng, Bin Yan
Given their powerful feature representation for recognition, deep convolutional neural networks (DCNNs) have been driving rapid advances in high-level computer vision tasks. However, their performance in semantic image segmentation is still not satisfactory. Based on the analysis of visual mechanism, we conclude that DCNNs in a bottom-up manner are not enough, because semantic image segmentation task requires not only recognition but also visual attention capability. In the study, superpixels containing visual attention information are introduced in a top-down manner, and an extensible architecture is proposed to improve the segmentation results of current DCNN-based methods...
2017: PloS One
https://www.readbyqxmd.com/read/28335318/a-label-free-and-sensitive-fluorescent-qualitative-assay-for-bisphenol-a-based-on-rolling-circle-amplification-exonuclease-iii-combined-cascade-amplification
#4
Xia Li, Juan Song, Qing-Wang Xue, Fu-Heng You, Xia Lu, Yan-Cong Kong, Shu-Yi Ma, Wei Jiang, Chen-Zhong Li
Bisphenol A (BPA) detection in drinking water and food packaging materials has attracted much attention since the discovery that BPA can interfere with normal physiological processes and cause adverse health effects. Here, we constructed a label-free aptamer fluorescent assay for selective and sensitive detection of BPA based on the rolling circle amplification (RCA)/Exonuclease III (Exo III)-combined cascade amplification strategy. First, the duplex DNA probe (RP) with anti-BPA aptamer and trigger sequence was designed for BPA recognition and signal amplification...
October 21, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28334799/the-relative-roles-of-anc-and-epi-in-the-continuous-distribution-of-llins-a-qualitative-study-in-four-countries
#5
Katherine Theiss-Nyland, Diakalia Koné, Corine Karema, Waqo Ejersa, Jayne Webster, Jo Lines
Background: The continuous distribution of long-lasting insecticidal nets (LLINs) for malaria prevention, through the antenatal care (ANC) and the Expanded Programme on Immunizations (EPI), is recommended by the WHO to improve and maintain LLIN coverage. Despite these recommendations, little is known about the relative strengths and weaknesses of the ANC and EPI-based LLIN distribution. This study aimed to explore and compare the roles of the ANC and EPI for LLIN distribution in four African countries...
December 26, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/28334795/everyday-stressors-in-deaf-and-hard-of-hearing-adolescents-the-role-of-coping-and-pragmatics
#6
Anat Zaidman-Zait, Adi Dotan
The current mixed-methods study examined everyday problems among deaf and hard of hearing (DHH) adolescents across various life domains. To better understand the factors influencing levels of perceived stress, the impact of DHH adolescents' coping and pragmatic abilities was also examined. Thirty DHH adolescents completed questionnaires about everyday stressors and coping, and 13 of these respondents were interviewed regarding their everyday problems. All participants used spoken language and attended mainstream high schools...
February 17, 2017: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/28334752/monitoring-the-consistency-quality-and-antioxidant-activity-of-da-hong-pao-teas-by-hplc-fingerprinting
#7
Lin Wang, Ting Yan, Lanping Yang, Kexia Zhang, Jingming Jia
In the present study, a high performance liquid chromatography (HPLC) method was developed and validated for fingerprint profiling to evaluate the quality consistency of the Da Hong Pao tea. The chromatographic separation was performed on a USA Waters C18 column (4.6 mm × 250 mm, 5 μm, Waters-XBridge Shield RP 18) with gradient elution. The column temperature was maintained at 30°C and the detection wavelength was set at 278 nm. The results demonstrated that the developed HPLC method achieved the desired linearity, precision, accuracy and limit of quantification...
February 18, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28334680/assessing-driving-forces-of-land-use-and-land-cover-change-by-a-mixed-method-approach-in-north-eastern-ghana-west-africa
#8
Janina Kleemann, Gülendam Baysal, Henry N N Bulley, Christine Fürst
Land use and land cover change (LULCC) is the result of complex human-environmental interactions. The high interdependencies in social-ecological systems make it difficult to identify the main drivers. However, knowledge of key drivers of LULCC, including indirect (underlying) drivers which cannot be easily determined by spatial or economic analyses, is essential for land use planning and especially important in developing countries. We used a mixed-method approach in order to detect drivers of LULCC in the Upper East Region of northern Ghana by different qualitative and quantitative methods which were compared in a confidence level analysis...
March 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28334638/targeted-physical-activity-messages-for-parents-of-children-with-disabilities-a-qualitative-investigation-of-parents-informational-needs-and-preferences
#9
R L Bassett-Gunter, R J Ruscitti, A E Latimer-Cheung, J L Fraser-Thomas
BACKGROUND AND AIM: Physical activity (PA) has myriad benefits for children with disabilities (CWD). Information and messaging campaigns can promote PA among CWD. The overall purpose of the study was to gain an understanding of the development of PA information and messages targeting parents of CWD. The specific objectives were to identify parents' preferences regarding PA information and messaging content and preferred methods and sources of communication. METHOD: Focus groups were conducted with parents of CWD (N=28)...
March 20, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28334101/refbool-a-reference-based-algorithm-for-discretizing-gene-expression-data
#10
Sascha Jung, Andras Hartmann, Antonio Del Sol
Motivation: The identification of genes or molecular regulatory mechanisms implicated in biological processes often requires the discretization, and in particular booleanization, of gene expression measurements. However, currently used methods mostly classify each measurement into an active or inactive state regardless of its statistical support possibly leading to downstream analysis conclusions based on spurious booleanization results. Results: In order to overcome the lack of certainty inherent in current methodologies and to improve the process of discretization, we introduce RefBool, a reference-based algorithm for discretizing gene expression data...
February 22, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28334078/relationships-between-morphologic-and-functional-patterns-in-the-polymicrogyric-cortex
#11
Matteo Lenge, Carmen Barba, Domenico Montanaro, Gayane Aghakhanyan, Francesca Frijia, Renzo Guerrini
Polymicrogyria is a malformation of cortical folding and layering underlying different cognitive and neurological manifestations. The polymicrogyric cortex has heterogeneous morphofunctional patterns, qualitatively described at magnetic resonance imaging (MRI) by variable severity gradients and functional activations. We investigated the link between abnormal cortical folding and cortical function in order to improve surgical planning for patients with polymicrogyria and intractable epilepsy. We performed structural and functional MRI on 14 patients with perisylvian polymicrogyria and adopted surface-based methods to detect alterations of cortical thickness (CT) and local gyrification index (LGI) compared with normal cortex (30 age-matched subjects)...
February 18, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28334023/preferences-for-the-provision-of-whole-genome-sequencing-services-among-young-adults
#12
Christopher H Wade, Kailyn R Elliott
OBJECTIVES: As whole genome sequencing (WGS) becomes increasingly available, clinicians will be faced with conveying complex information to individuals at different stages in life. The purpose of this study is to characterize the views of young adults toward obtaining WGS, learning different types of genomic information, and having choice about which results are disclosed. METHODS: A mixed-methods descriptive study was conducted with a diverse group of 18 and 19-years-olds (N = 145)...
2017: PloS One
https://www.readbyqxmd.com/read/28333463/determination-of-the-absolute-configuration-of-a-monoglyceride-antibolting-compound-and-isolation-of-related-compounds-from-radish-leaves-raphanus-sativus
#13
Tsuyoshi Ogihara, Naruki Amano, Yuki Mitsui, Kaien Fujino, Hiroyuki Ohta, Kosaku Takahashi, Hideyuki Matsuura
A monoglyceride (1) has been reported to possess an antibolting effect in radish (Raphanus sativus), but its absolute configuration at the C-2 position was not determined earlier. In this work, the absolute configuration of 1 was determined to be (2S), and it was also accompanied by one new (2) and two known monoglycerides (3 and 4). The chemical structure of 2 was determined as β-(7'Z,10'Z,13'Z)-hexadecatrienoic acid monoglyceride (β-16:3 monoglyceride). Qualitative and quantitative analytical methods for compounds 1-4 were developed, using two deuterium-labeled compounds (8 and 9) as internal standards...
March 23, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28333334/a-mixed-method-evaluation-of-peer-education-workshops-for-school-aged-children-to-teach-about-antibiotics-microbes-and-hygiene
#14
Vicki L Young, Amy Cole, Donna M Lecky, Dennis Fettis, Beth Pritchard, Neville Q Verlander, Charlotte V Eley, Cliodna A M McNulty
Background: Delivering health topics in schools through peer education is known to be beneficial for all students involved. In this study, we have evaluated a peer-education workshop that aims to educate primary and secondary school students on hygiene, the spread of infection and antibiotics. Methods: Four schools in south-west England, in a range of localities, took part in peer-education workshops, with students completing before, after and knowledge-retention questionnaires...
March 18, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28333308/fluconazole-treatment-enhances-extracellular-release-of-red-pigments-in-the-fungus-monascus-purpureus
#15
Sunil H Koli, Rahul K Suryawanshi, Chandrashekar D Patil, Satish V Patil
Traditional methods for the production of food grade pigments from fungus Monascus spp. are mostly relying on submerged fermentation. However, cell bound nature and intracellular accumulation of pigments in Monascus spp is the major hurdle in pigment production by submerged fermentation. The present study focused on the investigation of the effect of the antifungal agent, fluconazole on red pigment production from Monascus purpureus (NMCC-PF01). At the optimized concentration of fluconazole (30 μg/ml), pigment production was found to be enhanced by 88% after 96 h and it remained constant even after further incubation up to 168 h...
March 15, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28333272/family-building-using-embryo-adoption-relationships-and-contact-arrangements-between-provider-and-recipient-families-a-mixed-methods-study
#16
Lucy Frith, Eric Blyth, Steve Lui
STUDY QUESTION: What contact arrangements are established between providers and recipients of embryos using Snowflakes® Embryo Adoption Program? SUMMARY ANSWER: Contact arrangements varied considerably and were generally positively described, although some challenges were acknowledged. WHAT IS KNOWN ALREADY: Reproductive technologies create new and diverse family forms, and the ways in which families created by embryo adoption are negotiated in practice have not been extensively investigated...
March 8, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28333155/network-analysis-a-novel-method-for-mapping-neonatal-acute-transport-patterns-in-california
#17
S N Kunz, J A F Zupancic, J Rigdon, C S Phibbs, H C Lee, J B Gould, J Leskovec, J Profit
OBJECTIVE: The objectives of this study are to use network analysis to describe the pattern of neonatal transfers in California, to compare empirical sub-networks with established referral regions and to determine factors associated with transport outside the originating sub-network. STUDY DESIGN: This cross-sectional database study included 6546 infants <28 days old transported within California in 2012. After generating a graph representing acute transfers between hospitals (n=6696), we used community detection techniques to identify more tightly connected sub-networks...
March 23, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28333088/multi-view-structural-local-subspace-tracking
#18
Jie Guo, Tingfa Xu, Guokai Shi, Zhitao Rao, Xiangmin Li
In this paper, we propose a multi-view structural local subspace tracking algorithm based on sparse representation. We approximate the optimal state from three views: (1) the template view; (2) the PCA (principal component analysis) basis view; and (3) the target candidate view. Then we propose a unified objective function to integrate these three view problems together. The proposed model not only exploits the intrinsic relationship among target candidates and their local patches, but also takes advantages of both sparse representation and incremental subspace learning...
March 23, 2017: Sensors
https://www.readbyqxmd.com/read/28332951/-cancer-was-a-speed-bump-in-my-path-to-enlightenment-a-qualitative-analysis-of-situational-coping-experiences-among-young-adult-survivors-of-childhood-cancer
#19
Rebecca H Foster, Amanda M Brouwer, Robyn Dillon, Matthew J Bitsko, Kamar Godder, Marilyn Stern
Young adult survivors of childhood cancer (N = 47) completed essays exploring situational coping within a mixed methods study. Data were qualitatively analyzed using consensual qualitative research-modified methodology. Five themes emerged: (1) initial reactions to cancer, (2) adjustment/coping with cancer diagnosis and treatment, (3) provisions of social support, (4) perceived effects of cancer experience, and (5) reflections on the cancer experience. Perceptions of childhood cancer experiences appear generally positive, with the majority of negative reactions emerging immediately following diagnosis...
February 15, 2017: Journal of Psychosocial Oncology
https://www.readbyqxmd.com/read/28332862/effective-practices-in-the-delivery-of-research-ethics-education-a-qualitative-review-of-instructional-methods
#20
E Michelle Todd, Brett S Torrence, Logan L Watts, Tyler J Mulhearn, Shane Connelly, Michael D Mumford
In order to delineate best practices for courses on research ethics, the goal of the present effort was to identify themes related to instructional methods reflected in effective research ethics and responsible conduct of research (RCR) courses. By utilizing a qualitative review, four themes relevant to instructional methods were identified in effective research ethics courses: active participation, case-based activities, a combination of individual and group approaches, and a small number of instructional methods...
March 1, 2017: Accountability in Research
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