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Dermatology

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https://www.readbyqxmd.com/read/29334280/comparison-of-guidelines-for-the-use-of-tnf-inhibitors-for-psoriasis-in-the-united-states-canada-europe-and-the-united-kingdom-a-critical-appraisal-and-comprehensive-review
#1
Vidhi V Shah, Erica B Lee, Shivani Reddy, Elaine J Lin, Jashin J Wu
PURPOSE: To compare and contrast evidence-based CPGs from leading dermatological organizations for the use of tumor necrosis factor inhibitors (TNFi) in psoriasis. MATERIALS AND METHODS: Guidelines from the British National Institute for Health and Care Excellence (NICE), the British Association of Dermatologists (BAD), the American Academy of Dermatology (AAD), the National Psoriasis Foundation (NPF), and the Canadian Dermatology Association (CDA) were reviewed and compared...
January 15, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29334174/trichloroacetic-acid-80-as-a-chemical-debridement-method-for-chronic-venous-leg-ulcers-a-pilot-study
#2
Rita R Pinheiro, Bruno Duarte, Joana Cabete
Debridement is essential for the optimal care of venous leg ulcers. Several debridement methods with different limitations may be deployed. Trichloroacetic acid (TCA) is used for several dermatological purposes. Its application as a chemical debridement method for leg ulcers has never been explored. We designed a prospective study to determine the role of 80% TCA solution as a chemical debridement method for leg ulcers, regarding efficacy and procedure-associated pain. Chronic venous leg ulcers were treated with 3 cycles of 80% TCA solution or curettage over 1 week...
January 15, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29334132/oxybutynin-3-gel-for-the-treatment-of-primary-focal-hyperhidrosis-in-adolescents-and-young-adults
#3
Nicholas V Nguyen, Jane Gralla, James Abbott, Anna L Bruckner
BACKGROUND/OBJECTIVES: There are no reliably effective, well-tolerated topical agents for the treatment of hyperhidrosis. We sought to evaluate the efficacy and tolerability of oxybutynin 3% gel in adolescents and young adults with primary focal hyperhidrosis. METHODS: Patients with severe axillary hyperhidrosis were treated with topical oxybutynin 3% gel for 4 weeks. Response to treatment was assessed by calculating change in Hyperhidrosis Disease Severity Score from baseline to weeks 1 and 4...
January 15, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29333668/a-photonumeric-scale-for-the-assessment-of-atrophic-facial-photodamage
#4
J Ayer, A Ahmed, E Duncan-Parry, P Beck, T W Griffiths, R E B Watson, C E M Griffiths
BACKGROUND: Photonumeric scales have consistently shown superiority over descriptive equivalents. They have the advantage of providing a consistent visual frame of reference by minimising variability in perception and subjectivity. A photonumeric scale to assess hypertrophic facial photodamage already exists. However, there is currently no objective measure for atrophic facial photodamage. To address this, we have devised a nine-point photonumeric standardised scale. OBJECTIVES: To design, test and validate a photonumeric scale for the assessment of atrophic facial photodamage against a descriptive scale for the same indication...
January 15, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29333029/flagellate-rash-an-unusual-complication-of-bleomycin-therapy-a-case-report-with-brief-review-of-literature
#5
Chaturbhuj Agrawal, Vineet Talwar, Rajeev Saini, Pradeep Babu
Chemotherapy-induced skin rashes are common toxicities encountered which require careful assessment and evaluation as rashes could be a manifestation of primary malignancy itself and a variety of drugs used in combination further complicate the clinical scenario. Bleomycin is an anticancer antibiotic derived from Streptomyces verticillus and has been commonly used in the treatment of Hodgkin's disease, germ cell tumors and for pleurodesis. There are various dermatological adverse effects of bleomycin which have been previously reported in literature including skin peeling, hyperkeratosis, nail bed changes, Raynaud's phenomenon, and palmoplantar desquamation...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29332710/socioeconomic-and-geographic-barriers-to-dermatology-care-in-urban-and-rural-us-populations
#6
Toral Vaidya, Lindsey Zubritsky, Ali Alikhan, Anne Housholder
No abstract text is available yet for this article.
February 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29332425/dermatological-manifestations-in-patients-undergoing-in-vitro-fertilisation-a-prospective-study
#7
Aradhana Sood, Suvash Sahu, Sandeep Karunakaran, Rajneesh K Joshi, Deep Kumar Raman
BACKGROUND: Changing sociodemographic patterns with an increase in the age of childbirth have affected fertility rates worldwide. With advancing reproductive medicine, assisted reproductive techniques (ARTs) are becoming common. While dermatological manifestations in normal pregnancies have been well documented, there is a paucity of data regarding cutaneous manifestations in patients undergoing ART. OBJECTIVES: The objectives of our study were to estimate the incidence and types of dermatological manifestations in patients undergoing in vitro fertilisation (IVF) and to study their associations with age, type of infertility, and outcome of the procedure...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29331035/noninvasive-optical-spectroscopy-for-identification-of-non-melanoma-skin-cancer-pilot-study
#8
David J Carpenter, Mirabelle B Sajisevi, Nikita Chapurin, Clifford Scott Brown, Tracy Cheng, Gregory M Palmer, Daniel S Stevenson, Caroline L Rao, Russell P Hall, Charles R Woodard
OBJECTIVE: Optical spectroscopy offers a noninvasive alternative to biopsy as a first-line screening tool for suspicious skin lesions. This study sought to define several optical parameters across malignant and benign tissue types. STUDY DESIGN: Prospective pilot trial utilizing the Zenalux IM1 optical spectroscopy device from April 2016 to February 2017. For each skin lesion, provider pre-biopsy probability of malignancy was compared to histolopathologic diagnosis...
January 13, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29330932/influences-for-gender-disparity-in-dermatology-in-north-america
#9
Ahmed Shah, Sabeena Jalal, Faisal Khosa
BACKGROUND: Despite constituting half the population, women represent a minority of active physicians and hold a small proportion of faculty leadership positions in North America. However, dermatology is one of the few specialties where women comprise a substantial portion of the workforce. This study explores extent and contributors to gender disparity in academic dermatology faculty positions, leadership, and research. METHODS: We collected data on academic faculty including leadership from the websites of accredited U...
February 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29328028/-skin-pathology-in-diabetes-mellitus-clinical-and-pathophysiological-correlations-review
#10
K Kochet, I Lytus, I Svistunov, O Sulaieva
Skin pathology is registered in vast majority of patients with diabetes mellitus (DM). Despite the abundance of publications on dermatological problems in DM, there is still a number of gaps to be discussed in terms of pathophysiological mechanisms. The goal of this review was to assess the mechanisms of development of different skin pathologies under DM. One of the key pathogenic mechanisms of skin lesions in diabetes is hyperglycemia and the effects of the advanced glycation end products, inducing oxidative stress, endothelial dysfunction and inflammation; that in its turn can accelerate the mechanisms of skin aging, the development of diabetic dermopathy and scleredema diabeticorum...
December 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29328012/-a-man-with-severe-skin-rash
#11
T V Nguyen, G L van Rooijen, M B A van Doorn
A 31-year-old man visited the outpatient clinic Dermatology with an exacerbation of his atopic eczema. Since a few day vesicles and crusts had appeared and his eyelids were swollen. He was known to have eczema, for which he was treated with ciclosporin 200 mg 2 times a day (4 mg/kg per day) since four months. Under this treatment the eczema used to be under control. There were no neurological symptoms or vision problems. At physical examination we saw erythematous papules, vesicles, superficial erosions and crusts on all body regions, but especially on the trunk and in the main neck region...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29327369/overweight-and-obesity-may-play-a-role-in-the-pathogenesis-of-chronic-spontaneous-urticaria
#12
M Zbiciak-Nylec, D Wcisło-Dziadecka, M Kasprzyk, A Kulig, J Laszczak, M Noworyta, S Adamus, L Brzezińska-Wcisło, B Rogala, Z Brzoza
BACKGROUND: Chronic spontaneous urticaria (CSU) is one of the commonest diseases in allergological and dermatological practice. It constitutes an interdisciplinary problem, and its pathogenesis is not always easily determined. It has been suggested that metabolic syndrome and hyperlipidaemia are more frequent in patients with CSU, but the influence of overweight and obesity on the development of CSU has not been thoroughly investigated. AIM: To assess the association between body parameters and the development of CSU...
January 12, 2018: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29327359/contact-sensitization-in-dental-technicians-with-occupational-contact-dermatitis-data-of-the-information-network-of-departments-of-dermatology-ivdk-2001-2015
#13
Annice Heratizadeh, Thomas Werfel, Steffen Schubert, Johannes Geier
BACKGROUND: Dental technicians (DTs) are at increased risk for allergic contact sensitization. OBJECTIVES: To assess the current spectrum of occupational sensitization in DTs with occupational contact dermatitis (OCD). METHODS: A retrospective analysis of Information Network of Departments of Dermatology patch test data from the years 2001-2015 concerning DTs with OCD was performed. RESULTS: Patients of the study group (226 DTs with OCD) were significantly more often diagnosed with allergic contact dermatitis (37...
January 12, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29326825/staphylococcal-scalded-skin-syndrome-a-pediatric-dermatology-case-report
#14
Girish Gulab Meshram, Neeraj Kaur, Kanwaljeet Singh Hura
Staphylococcal scalded skin syndrome is a condition which predominantly affects children and causes a spectrum of skin lesions. We present a case of a 2-month-old infant with complaints of fever and fragile blisters over the body. The mucosal areas were spared. The diagnosis of staphylococcal scalded skin syndrome was reached on clinical grounds and culture report. The patient responded well to the treatment, which included an antibiotic (cloxacillin), an analgesic (paracetamol), and hydration with intravenous fluids...
2018: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29325749/sustained-improvement-of-psoriasis-associated-with-hcv-after-virologic-response-to-sofosbuvir-ribavirin
#15
Asem Ahmed Elfert
An 18 year old boy attended a dermatology clinic outside our hospital and diagnosed with psoriasis. His skin lesions over both ankles (Fig. 1) did not improve at all with potent local steroids twice for 3 months, then 3 times daily for another 3 months. His dermatologist talked to him about using methotrexate and asked for liver function tests before starting the systemic therapy. His ALT and AST were doubled. The patient came to our Hepatology clinic worried about his elevated liver enzymes. We asked for viral markers...
January 8, 2018: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/29324959/surveillance-of-intradomiciliary-contacts-of-leprosy-cases-perspective-of-the-client-in-a-hyperendemic-municipality
#16
Helizandra Simoneti Bianchini Romanholo, Eliana Amorim de Souza, Alberto Novaes Ramos Júnior, Adélia Cileode Gomes Castelo Branco Kaiser, Ismália Oliveira da Silva, Aline Lima Brito, Cídia Vasconcellos
OBJECTIVE: To characterize approach methods for intradomiciliary contacts (IdC) of leprosy cases resident in Northern Brazil, during 2001-2012. METHOD: A cross-sectional and descriptive study in the state of Rondônia. Included IdC of leprosy cases diagnosed/reported in SINAN-Ministry of Health (MS), 2001-2012. A semi-structured instrument was applied to the IdCs, with six interventions: complete dermatological examination; complete neurological examination; BCG vaccination; instructions for return to the health unit; BCG guidance; and guidance to mobilize other contacts...
January 2018: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29323824/a-case-of-atypical-synovitis-acne-pustulosis-hyperostosis-osteitis-sapho-syndrome-presenting-with-osteomyelitis-of-the-clavicle
#17
Chetan Sharma, Brian Chow
Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is considered after exclusion of infection and arthritis; however, microbial infection may be present in osteoarticular lesions of these patients. Chronic osteomyelitis and associated bacterial infection were detected in a recurrent osteoarticular lesion in an adolescent patient with a history of clavicle pain, who complained of recurrent swelling in the left clavicle. Most pediatric case reports of SAPHO syndrome describe patients with associated skin conditions...
June 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29322710/etiology-and-outcomes-of-lower-limb-ulcers-in-non-diabetic-patients-an-experience-from-government-hospital-in-western-india
#18
Yojana Gokhale, Amol Raut, Divya Kunal Lala, Rushabh Kothari, Lalana Kalekar, Amol Kamble
Aim: To study the Etiology and Outcomes of Lower Extremity Ulcer in Non- Diabetic Patients. Method: A total number of 40 patients were collected from Rheumatology services (Department of Medicine), Venous Clinic (Department of Surgery) and Dermatology Clinic (Department of Dermatology) of a tertiary care hospital in Mumbai over a period of 48 months from January 2013 to December 2016. The study included serial recruitment of lower limb ulcer fulfilling inclusion criteria...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29322532/factors-associated-with-p-phenylenediamine-sensitization-data-from-the-information-network-of-departments-of-dermatology-2008-2013
#19
Steffen Schubert, Holger Lessmann, Axel Schnuch, Wolfgang Uter, Johannes Geier
BACKGROUND: Risk factors for p-phenylenediamine (PPD) sensitization include the use of hair dyes, the application of temporary black henna tattoos, working as a hairdresser, and, possibly, exposure to hair dye pretests. OBJECTIVES: To quantify the impact of these (putative) risk factors on PPD sensitization. METHODS: Six items related to PPD exposure were added to the routine Information Network of Departments of Dermatology questionnaire from 2008 to 2013...
January 11, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29322197/jama-dermatology
#20
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2018: JAMA Dermatology
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