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Ativan and elderly

M H Zisselman, B W Rovner, K G Kelly, C Woods
OBJECTIVE: To assess benzodiazepine utilization and documentation in hospitalized medical and surgical patients in relation to demographic characteristics. METHODS: Retrospective review of computerized university hospital database and medical records. SUBJECTS: 6,020 consecutive medical and surgical admissions from January through June 1992. MEASUREMENTS: Utilization of four commonly prescribed benzodiazepines (Halcion, Ativan, Valium, Xanax) in relation to age, race, sex, length of stay, hospital service; and documentation of indications for use...
1994: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
A M Barclay
Caution is required when prescribing psychotropic drugs to elderly patients, because of altered pharmacokinetics. Benzodiazepines with a relatively short half-life, such as temazepam (Restoril), alprazolam (Xanax), and lorazepam (Ativan), are better hypnotics for the elderly than those with a long half-life. Lorazepam and clorazepate dipotassium (Tranxene) are appropriate anxiolytics for elderly patients. Antipsychotics have anticholinergic and extrapyramidal symptoms in varying degrees. Thiothixene (Navane) and haloperidol (Haldol) in low doses are the drugs of choice despite their extrapyramidal symptoms...
June 1985: Postgraduate Medicine
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