Sameer Bansilal, Marc P Bonaca, Jan H Cornel, Robert F Storey, Deepak L Bhatt, Ph Gabriel Steg, Kyungah Im, Sabina A Murphy, Dominick J Angiolillo, Robert G Kiss, Alexander N Parkhomenko, Jose Lopez-Sendon, Daniel Isaza, Assen Goudev, Frederic Kontny, Peter Held, Eva C Jensen, Eugene Braunwald, Marc S Sabatine, A J Oude Ophuis
BACKGROUND: Patients with prior myocardial infarction (MI) and multivessel coronary disease (MVD) are at high risk for recurrent coronary events. OBJECTIVES: The authors investigated the efficacy and safety of ticagrelor versus placebo in patients with MVD in the PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis In Myocardial Infarction 54) trial. METHODS: Patients with a history of MI 1 to 3 years before inclusion in the PEGASUS-TIMI 54 trial were stratified in a pre-specified analysis based on the presence of MVD...
February 6, 2018: Journal of the American College of Cardiology