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White coat effect

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https://www.readbyqxmd.com/read/28814863/gentamicin-coating-of-nanotubular-anodized-titanium-implant-reduces-implant-related-osteomyelitis-and-enhances-bone-biocompatibility-in-rabbits
#1
Denghui Liu, Chongru He, Zhongtang Liu, Weidong Xu
Titanium and titanium alloy are widely used as orthopedic implants for their favorable mechanical properties and satisfactory biocompatibility. The aim of the present study was to investigate the antibacterial effect and bone cell biocompatibility of a novel implant made with nanotubular anodized titanium coated with gentamicin (NTATi-G) through in vivo study in rabbits. The animals were divided into four groups, each receiving different kinds of implants, that is, NTATi-G, titanium coated with gentamicin (Ti-G), nanotubular anodized titanium uncoated with gentamicin (NTATi) and titanium uncoated with gentamicin (Ti)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28791210/biosynthesis-of-mgo-nanoparticles-using-mushroom-extract-effect-on-peanut-arachis-hypogaea-l-seed-germination
#2
K Jhansi, N Jayarambabu, K Paul Reddy, N Manohar Reddy, R Padma Suvarna, K Venkateswara Rao, V Ramesh Kumar, V Rajendar
Current study describes the green, environmental friendly, and cost-effectiveness technique for the preparation of MgO nanoparticles (NPs) via white button mushroom aqueous extract. The synthesized MgO NPs were characterized using equipments such as X-ray diffraction, dynamic light scattering (DLS), scanning electron microscope (SEM), energy dispersive spectroscopy (EDS), and thermal gravimetric analysis (TGA) for average crystalline size, particle size, morphology, elemental analysis, and weight loss of the materials, respectively...
August 2017: 3 Biotech
https://www.readbyqxmd.com/read/28775265/silk-hydrogel-lenses-for-light-emitting-diodes
#3
Rustamzhon Melikov, Daniel Aaron Press, Baskaran Ganesh Kumar, Itir Bakis Dogru, Sadra Sadeghi, Mariana Chirea, İskender Yılgör, Sedat Nizamoglu
Today the high demand for electronics leads to massive production of waste, thus green materials based electronic devices are becoming more important for environmental protection and sustainability. The biomaterial based hydrogels are widely used in tissue engineering, but their uses in photonics are limited. In this study, silk fibroin protein in hydrogel form is explored as a bio-friendly alternative to conventional polymers for lens applications in light-emitting diodes. The concentration of silk fibroin protein and crosslinking agent had direct effects on optical properties of silk hydrogel...
August 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28769596/more-accurate-systolic-blood-pressure-measurement-is-required-for-improved-hypertension-management-a-perspective
#4
Meir Nitzan, Itzchak Slotki, Linda Shavit
The commonly used techniques for systolic blood pressure (SBP) and diastolic blood pressure (DBP) measurement are the auscultatory Korotkoff-based sphygmomanometry and oscillometry. The former technique is relatively accurate but is limited to a physician's office because its automatic variant is subject to noise artifacts. Consequently, the Korotkoff-based measurement overestimates the blood pressure in some patients due to white coat effect, and because it is a single measurement, it cannot properly represent the variable blood pressure...
2017: Medical Devices: Evidence and Research
https://www.readbyqxmd.com/read/28727097/evaluating-the-impact-of-breed-pregnancy-and-hair-coat-on-body-temperature-and-sweating-rate-of-hair-sheep-ewes-in-the-tropics
#5
R W Godfrey, W D Preston, S R Joseph, L LaPlace, P E Hillman, K G Gebremedhin, C N Lee, R J Collier
The objective of this study was to evaluate the effect of pregnancy, breed, and hair coat on body temperature and sweating rate (SR) of hair sheep. St. Croix White (STX; = 9) and Dorper × STX (DRPX; = 9) ewes (3.6 yr of age) were evaluated over 4 d at 126 d of gestation (PREG) and over 4 d at 46 d postpartum (OPEN) in the shade and sun and in the morning (AM; 0900 to 1200 h) and afternoon (PM; 1300 to 1600 h) after a 20 min acclimation to each condition on each day. Data loggers recorded vaginal temperature (VT) at 10-min intervals for 96 h...
July 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28703777/physiological-effects-of-touching-coated-wood
#6
Harumi Ikei, Chorong Song, Yoshifumi Miyazaki
This study examined the physiological effects of touching wood with various coating with the palm of the hand on brain activity and autonomic nervous activity. Participants were 18 female university students (mean age, 21.7 ± 1.6 years). As an indicator of brain activity, oxyhemoglobin concentrations were measured in the left and right prefrontal cortices using near-infrared time-resolved spectroscopy. Heart rate variability (HRV) and heart rate were used as indicators of autonomic nervous activity. The high-frequency (HF) component of HRV, which reflects parasympathetic nervous activity, and the low-frequency (LF)/HF ratio, which reflects sympathetic nervous activity, were measured...
July 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28701707/anti-cancerous-effect-of-albumin-coated-silver-nanoparticles-on-mda-mb-231-human-breast-cancer-cell-line
#7
Marzieh Azizi, Hedayatoallah Ghourchian, Fatemeh Yazdian, Shahla Bagherifam, Sara Bekhradnia, Bo Nyström
With the aim of making specific targeting of silver nanoparticles as a drug for tumor cells and developing new anticancer agents, a novel nano-composite was developed. Albumin coated silver nanoparticles (ASNPs) were synthesized, and their anti-cancerous effects were evaluated against MDA-MB 231, a human breast cancer cell line. The synthesized ASNPs were characterized by spectroscopic methods. The morphological changes of the cells were observed by inverted, florescent microscopy and also by DNA ladder pattern on gel electrophoresis; the results revealed that the cell death process occurred through the apoptosis mechanism...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28696223/white-coat-effect-is-uncommon-in-patients-with-refractory-hypertension
#8
Mohammed Siddiqui, Eric K Judd, Suzanne Oparil, David A Calhoun
Refractory hypertension is a recently described phenotype of antihypertensive treatment failure defined as uncontrolled blood pressure (BP) despite the use of ≥5 different antihypertensive agents, including chlorthalidone and spironolactone. Recent studies indicate that refractory hypertension is uncommon, with a prevalence of ≈5% to 10% of patients referred to a hypertension specialty clinic for uncontrolled hypertension. The prevalence of white-coat effect, that is, uncontrolled automated office BP ≥135/85 mm Hg and controlled out-of-office BP <135/85 mm Hg, by awake ambulatory BP monitor in hypertensive patients overall is ≈30% to 40%...
September 2017: Hypertension
https://www.readbyqxmd.com/read/28688364/in-vivo-study-of-microarc-oxidation-coated-biodegradable-magnesium-plate-to-heal-bone-fracture-defect-of-3mm-width
#9
Y F Wu, Y M Wang, Y B Jing, J P Zhuang, J L Yan, Z K Shao, M S Jin, C J Wu, Y Zhou
Microarc oxidation (MAO) coated magnesium (Mg) with improved corrosion resistance appeal increasing interests as a revolutionary biodegradable metal for fractured bone fixing implants application. However, the in vivo corrosion degradation of the implants and bone healing response are not well understood, which is highly required in clinic. In the present work, 10μm and 20μm thick biocompatible MAO coatings mainly composed of MgO, Mg2SiO4, CaSiO3 and Mg3(PO4)2 phases were fabricated on AZ31 magnesium alloy...
June 23, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28685205/the-effects-of-titanium-dioxide-coatings-on-light-derived-heating-and-transdermal-heat-transfer-in-bovine-skin
#10
S J Bartle, D U Thomson, R Gehring, D van der Merwe
The effects of titanium dioxide coatings of bovine hides on light absorption and transdermal transfer of light-derived heat were investigated. Four hair-on rug hides from Holstein cattle were purchased. Twelve samples about 20 cm on a side were cut from each hide; nine from the black-colored areas, and three from the white areas. Samples were randomized and assigned to four coating treatments: (1) white hide with no coating (White), (2) black hide with no coating (Black), (3) black hide with 50% coating (Mid), and (4) black hide with 100% coating (High)...
July 7, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28676873/design-preparation-and-performance-of-a-novel-drug-eluting-stent-with-multiple-layer-coatings
#11
Tingzhang Hu, Song Lin, Ruolin Du, Meiling Fu, Qiong Rao, Tieying Yin, Yan Huang, Guixue Wang
Drug-eluting stents (DESs) can effectively control the harmful effects of coronary artery disease, because of their excellent ability to reduce in-stent restenosis. However, delayed re-endothelialization and late stent thrombosis have caused concern over the safety of DESs. In this study, according to time-ordered pathological responses after stent implantation, a hierarchical multiple drug-eluting stent was designed and prepared to overcome the existing DES limitations. A platelet membrane glycoprotein IIIa monoclonal antibody (SZ-21) and a vascular endothelial growth factor (VEGF121) were loaded into the inner coating of 316L stainless steel (316L SS) stents to inhibit thrombosis and promote re-endothelialization; rapamycin (RAPA) was loaded into the third layer to inhibit intima hyperplasia; a drug-free poly-l-lactic acid coating was located on the second and fourth layers and used as sustained release layers...
July 5, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28676236/white-coat-effect-in-hypertensive-patients-the-role-of-hospital-environment-or-physician-presence
#12
Xi-Xing Wang, Wei Shuai, Qiang Peng, Ju-Xiang Li, Ping Li, Xiao-Shu Cheng, Hai Su
This study was to evaluate the role of hospital environment or physician presence for white coat effect (WCE) in hypertensive patients. At first, 54 hypertensive outpatients diagnosed on office blood pressure (OBP) were included for 2-week placebo run in. During the second week of the run in period, home BP was measured using electronic BP monitors for 5-7 days. Finally, 26 sustained hypertensive patients with home systolic BP/diastolic BP over 135/85 (but <180/110) mm Hg were enrolled for 8-week treatment of nifedipine controlled-release tablet...
June 21, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28670638/a-comparison-of-rapid-diagnostic-testing-by-plasmodium-lactate-dehydrogenase-and-quantitative-buffy-coat-technique-in-malaria-diagnosis-in-children
#13
Ifeanyi Kanayo Ifeorah, Biobele J Brown, Olugbemiro O Sodeinde
BACKGROUND: The World Health Organization (WHO) considers early and rapid diagnosis as one of the strategies to control malaria. This study compared the performance of Quantitative Buffy Coat (QBC) test and the Plasmodium lactate dehydrogenase (pLDH) rapid diagnostic test (RDT) with microscopy as the gold standard. MATERIALS AND METHODS: The study involved children ages 0-5 years who presented with a history of fever at the University College Hospital, Ibadan, Nigeria...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28662929/isolation-and-characterization-of-a-novel-cervid-adenovirus-from-white-tailed-deer-odocoileus-virginianus-fawns-in-a-captive-herd
#14
Julia F Ridpath, John D Neill, Mitchel V Palmer, Fernando V Bauermann, Shollie M Falkenberg, Peregrine L Wolff
A novel adenovirus, CeAdV1, was isolated from buffy coat and nasal swab samples collected from two captive white-tailed deer (Odocoileus virginianus) fawns. The isolation was an incidental finding in the course of screening animals for use in a research study on an unrelated pathogen. In the screening process, virus isolation was performed on both nasal swabs and buffy coat samples and cytopathic effect was observed. Electron microscopy revealed viral particles with the shape and morphology of an adenovirus...
June 27, 2017: Virus Research
https://www.readbyqxmd.com/read/28652731/enhanced-antitumor-activity-of-surface-modified-iron-oxide-nanoparticles-and-an-%C3%AE-tocopherol-derivative-in-a-rat-model-of-mammary-gland-carcinosarcoma
#15
Daniel Horák, Vitaliy Igorovych Pustovyy, Andrii Valeriyovich Babinskyi, Olga Mikhailovna Palyvoda, Vasyl Fedorovich Chekhun, Igor Nikolaevich Todor, Oleksandr Ivanovich Kuzmenko
Maghemite (γ-Fe2O3) nanoparticles were obtained by coprecipitation of ferrous and ferric salts in an alkaline medium followed by oxidation; the nanoparticles were coated with poly(N,N-dimethylacrylamide) (PDMA) and characterized by transmission electron microscopy, attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy, dynamic light scattering, thermogravimetric and elemental analyses, and magnetic measurements in terms of particle morphology, size, polydispersity, amount of coating, and magnetization, respectively...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28616059/supramolecular-structure-of-dietary-fat-in-early-life-modulates-expression-of-markers-for-mitochondrial-content-and-capacity-in-adipose-tissue-of-adult-mice
#16
Andrea Kodde, Eline M van der Beek, Esther Phielix, Eefje Engels, Lidewij Schipper, Annemarie Oosting
BACKGROUND: Previous studies have shown that early life nutrition can modulate the development of white adipose tissue and thereby affect the risk on obesity and metabolic disease later in life. For instance, postnatal feeding with a concept infant milk formula with large, phospholipid coated lipid droplets (Concept, Nuturis®), resulted in reduced adiposity in adult mice. The present study investigated whether differences in cell energy metabolism, using markers of mitochondrial content and capacity, may contribute to the observed effects...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28610487/establishment-of-novel-meniscal-scaffold-structures-using-polyglycolic-and-poly-l-lactic-acids
#17
Tomohiko Murakami, Shuhei Otsuki, Kosuke Nakagawa, Yoshinori Okamoto, Tae Inoue, Yuki Sakamoto, Hideki Sato, Masashi Neo
The purpose of this study was to evaluate various types of meniscus scaffolds that mimic the meniscus structure, and to establish a novel cell-free meniscus scaffold with polyglycolic acid or poly-l-lactic acid. Four types of scaffolds were implanted into Japanese white rabbits: poly-l-lactic acid sponge poly-l-lactic acid, PGA-coated PLLA sponge, PGA lamination, and film-coated PGA lamination. Samples were harvested at 8 and 12 weeks after implantation, and a compression stress test was performed. The meniscus size and Ishida scores were evaluated for regenerated tissue...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28555286/-management-of-arterial-hypertension
#18
J A Wermelt, H Schunkert
Arterial hypertension has a high prevalence and is a major risk factor for the development of cardiovascular diseases. It is a major contributor to worldwide morbidity and mortality and hence poses a huge socioeconomic burden. Despite great progress in perception, diagnosis and treatment of hypertension, blood pressure control is inadequate in less than half of the hypertensive patients (<140/90 mm Hg). The diagnosis of arterial hypertension starts in most patients with the conventional office blood pressure measurement...
August 2017: Herz
https://www.readbyqxmd.com/read/28549461/the-effect-of-white-coats-and-gender-on-medical-students-perceptions-of-physicians
#19
Malika Ladha, Aleem Bharwani, Kevin McLaughlin, Henry T Stelfox, Adam Bass
BACKGROUND: Despite the fact that medical schools spend a considerable effort to rate clinical instructors, there is limited evidence regarding the effect of physical characteristics on instructor ratings. White coats have been shown to alter patients' perceptions of physicians although it has not been determined if preceptors who wear white coats are rated differently than their colleagues. METHODS: Second year medical students were administered a questionnaire with four clinical scenarios depicting medical errors accompanied by a picture of a physician of different sexes and ethnicities...
May 26, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28540180/hemoglobin-and-mean-platelet-volume-predicts-diffuse-t1-mri-white-matter-volume-decrease-in-sickle-cell-disease-patients
#20
Soyoung Choi, Adam M Bush, Matthew T Borzage, Anand A Joshi, William J Mack, Thomas D Coates, Richard M Leahy, John C Wood
Sickle cell disease (SCD) is a life-threatening genetic condition. Patients suffer from chronic systemic and cerebral vascular disease that leads to early and cumulative neurological damage. Few studies have quantified the effects of this disease on brain morphometry and even fewer efforts have been devoted to older patients despite the progressive nature of the disease. This study quantifies global and regional brain volumes in adolescent and young adult patients with SCD and racially matched controls with the aim of distinguishing between age related changes associated with normal brain maturation and damage from sickle cell disease...
2017: NeuroImage: Clinical
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