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White coat effect

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https://www.readbyqxmd.com/read/28727097/evaluating-the-impact-of-breed-pregnancy-and-hair-coat-on-body-temperature-and-sweating-rate-of-hair-sheep-ewes-in-the-tropics
#1
R W Godfrey, W D Preston, S R Joseph, L LaPlace, P E Hillman, K G Gebremedhin, C N Lee, R J Collier
The objective of this study was to evaluate the effect of pregnancy, breed, and hair coat on body temperature and sweating rate (SR) of hair sheep. St. Croix White (STX; = 9) and Dorper × STX (DRPX; = 9) ewes (3.6 yr of age) were evaluated over 4 d at 126 d of gestation (PREG) and over 4 d at 46 d postpartum (OPEN) in the shade and sun and in the morning (AM; 0900 to 1200 h) and afternoon (PM; 1300 to 1600 h) after a 20 min acclimation to each condition on each day. Data loggers recorded vaginal temperature (VT) at 10-min intervals for 96 h...
July 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28701707/anti-cancerous-effect-of-albumin-coated-silver-nanoparticles-on-mda-mb-231-human-breast-cancer-cell-line
#2
Marzieh Azizi, Hedayatoallah Ghourchian, Fatemeh Yazdian, Shahla Bagherifam, Sara Bekhradnia, Bo Nyström
With the aim of making specific targeting of silver nanoparticles as a drug for tumor cells and developing new anticancer agents, a novel nano-composite was developed. Albumin coated silver nanoparticles (ASNPs) were synthesized, and their anti-cancerous effects were evaluated against MDA-MB 231, a human breast cancer cell line. The synthesized ASNPs were characterized by spectroscopic methods. The morphological changes of the cells were observed by inverted, florescent microscopy and also by DNA ladder pattern on gel electrophoresis; the results revealed that the cell death process occurred through the apoptosis mechanism...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28696223/white-coat-effect-is-uncommon-in-patients-with-refractory-hypertension
#3
Mohammed Siddiqui, Eric K Judd, Suzanne Oparil, David A Calhoun
Refractory hypertension is a recently described phenotype of antihypertensive treatment failure defined as uncontrolled blood pressure (BP) despite the use of ≥5 different antihypertensive agents, including chlorthalidone and spironolactone. Recent studies indicate that refractory hypertension is uncommon, with a prevalence of ≈5% to 10% of patients referred to a hypertension specialty clinic for uncontrolled hypertension. The prevalence of white coat effect, that is, uncontrolled automated office BP ≥135/85 mm Hg and controlled out-of-office BP <135/85 mm Hg, by awake ambulatory BP monitor in hypertensive patients overall is ≈30% to 40%...
July 10, 2017: Hypertension
https://www.readbyqxmd.com/read/28688364/in-vivo-study-of-microarc-oxidation-coated-biodegradable-magnesium-plate-to-heal-bone-fracture-defect-of-3mm-width
#4
Y F Wu, Y M Wang, Y B Jing, J P Zhuang, J L Yan, Z K Shao, M S Jin, C J Wu, Y Zhou
Microarc oxidation (MAO) coated magnesium (Mg) with improved corrosion resistance appeal increasing interests as a revolutionary biodegradable metal for fractured bone fixing implants application. However, the in vivo corrosion degradation of the implants and bone healing response are not well understood, which is highly required in clinic. In the present work, 10μm and 20μm thick biocompatible MAO coatings mainly composed of MgO, Mg2SiO4, CaSiO3 and Mg3(PO4)2 phases were fabricated on AZ31 magnesium alloy...
June 23, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28685205/the-effects-of-titanium-dioxide-coatings-on-light-derived-heating-and-transdermal-heat-transfer-in-bovine-skin
#5
S J Bartle, D U Thomson, R Gehring, D van der Merwe
The effects of titanium dioxide coatings of bovine hides on light absorption and transdermal transfer of light-derived heat were investigated. Four hair-on rug hides from Holstein cattle were purchased. Twelve samples about 20 cm on a side were cut from each hide; nine from the black-colored areas, and three from the white areas. Samples were randomized and assigned to four coating treatments: (1) white hide with no coating (White), (2) black hide with no coating (Black), (3) black hide with 50% coating (Mid), and (4) black hide with 100% coating (High)...
July 7, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28676873/design-preparation-and-performance-of-a-novel-drug-eluting-stent-with-multiple-layer-coatings
#6
Tingzhang Hu, Song Lin, Ruolin Du, Meiling Fu, Qiong Rao, Tieying Yin, Yan Huang, Guixue Wang
Drug-eluting stents (DESs) can effectively control the harmful effects of coronary artery disease, because of their excellent ability to reduce in-stent restenosis. However, delayed re-endothelialization and late stent thrombosis have caused concern over the safety of DESs. In this study, according to time-ordered pathological responses after stent implantation, a hierarchical multiple drug-eluting stent was designed and prepared to overcome the existing DES limitations. A platelet membrane glycoprotein IIIa monoclonal antibody (SZ-21) and a vascular endothelial growth factor (VEGF121) were loaded into the inner coating of 316L stainless steel (316L SS) stents to inhibit thrombosis and promote re-endothelialization; rapamycin (RAPA) was loaded into the third layer to inhibit intima hyperplasia; a drug-free poly-l-lactic acid coating was located on the second and fourth layers and used as sustained release layers...
July 5, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28676236/white-coat-effect-in-hypertensive-patients-the-role-of-hospital-environment-or-physician-presence
#7
Xi-Xing Wang, Wei Shuai, Qiang Peng, Ju-Xiang Li, Ping Li, Xiao-Shu Cheng, Hai Su
This study was to evaluate the role of hospital environment or physician presence for white coat effect (WCE) in hypertensive patients. At first, 54 hypertensive outpatients diagnosed on office blood pressure (OBP) were included for 2-week placebo run in. During the second week of the run in period, home BP was measured using electronic BP monitors for 5-7 days. Finally, 26 sustained hypertensive patients with home systolic BP/diastolic BP over 135/85 (but <180/110) mm Hg were enrolled for 8-week treatment of nifedipine controlled-release tablet...
June 21, 2017: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/28670638/a-comparison-of-rapid-diagnostic-testing-by-plasmodium-lactate-dehydrogenase-and-quantitative-buffy-coat-technique-in-malaria-diagnosis-in-children
#8
Ifeanyi Kanayo Ifeorah, Biobele J Brown, Olugbemiro O Sodeinde
BACKGROUND: The World Health Organization (WHO) considers early and rapid diagnosis as one of the strategies to control malaria. This study compared the performance of Quantitative Buffy Coat (QBC) test and the Plasmodium lactate dehydrogenase (pLDH) rapid diagnostic test (RDT) with microscopy as the gold standard. MATERIALS AND METHODS: The study involved children ages 0-5 years who presented with a history of fever at the University College Hospital, Ibadan, Nigeria...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28662929/isolation-and-characterization-of-a-novel-cervid-adenovirus-from-white-tailed-deer-odocoileus-virginianus-fawns-in-a-captive-herd
#9
Julia F Ridpath, John D Neill, Mitchel V Palmer, Fernando V Bauermann, Shollie M Falkenberg, Peregrine L Wolff
A novel adenovirus, CeAdV1, was isolated from buffy coat and nasal swab samples collected from two captive white-tailed deer (Odocoileus virginianus) fawns. The isolation was an incidental finding in the course of screening animals for use in a research study on an unrelated pathogen. In the screening process, virus isolation was performed on both nasal swabs and buffy coat samples and cytopathic effect was observed. Electron microscopy revealed viral particles with the shape and morphology of an adenovirus...
June 27, 2017: Virus Research
https://www.readbyqxmd.com/read/28652731/enhanced-antitumor-activity-of-surface-modified-iron-oxide-nanoparticles-and-an-%C3%AE-tocopherol-derivative-in-a-rat-model-of-mammary-gland-carcinosarcoma
#10
Daniel Horák, Vitaliy Igorovych Pustovyy, Andrii Valeriyovich Babinskyi, Olga Mikhailovna Palyvoda, Vasyl Fedorovich Chekhun, Igor Nikolaevich Todor, Oleksandr Ivanovich Kuzmenko
Maghemite (γ-Fe2O3) nanoparticles were obtained by coprecipitation of ferrous and ferric salts in an alkaline medium followed by oxidation; the nanoparticles were coated with poly(N,N-dimethylacrylamide) (PDMA) and characterized by transmission electron microscopy, attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy, dynamic light scattering, thermogravimetric and elemental analyses, and magnetic measurements in terms of particle morphology, size, polydispersity, amount of coating, and magnetization, respectively...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28616059/supramolecular-structure-of-dietary-fat-in-early-life-modulates-expression-of-markers-for-mitochondrial-content-and-capacity-in-adipose-tissue-of-adult-mice
#11
Andrea Kodde, Eline M van der Beek, Esther Phielix, Eefje Engels, Lidewij Schipper, Annemarie Oosting
BACKGROUND: Previous studies have shown that early life nutrition can modulate the development of white adipose tissue and thereby affect the risk on obesity and metabolic disease later in life. For instance, postnatal feeding with a concept infant milk formula with large, phospholipid coated lipid droplets (Concept, Nuturis®), resulted in reduced adiposity in adult mice. The present study investigated whether differences in cell energy metabolism, using markers of mitochondrial content and capacity, may contribute to the observed effects...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28610487/establishment-of-novel-meniscal-scaffold-structures-using-polyglycolic-and-poly-l-lactic-acids
#12
Tomohiko Murakami, Shuhei Otsuki, Kosuke Nakagawa, Yoshinori Okamoto, Tae Inoue, Yuki Sakamoto, Hideki Sato, Masashi Neo
The purpose of this study was to evaluate various types of meniscus scaffolds that mimic the meniscus structure, and to establish a novel cell-free meniscus scaffold with polyglycolic acid or poly-l-lactic acid. Four types of scaffolds were implanted into Japanese white rabbits: poly-l-lactic acid sponge poly-l-lactic acid, PGA-coated PLLA sponge, PGA lamination, and film-coated PGA lamination. Samples were harvested at 8 and 12 weeks after implantation, and a compression stress test was performed. The meniscus size and Ishida scores were evaluated for regenerated tissue...
January 1, 2017: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/28555286/-management-of-arterial-hypertension
#13
J A Wermelt, H Schunkert
Arterial hypertension has a high prevalence and is a major risk factor for the development of cardiovascular diseases. It is a major contributor to worldwide morbidity and mortality and hence poses a huge socioeconomic burden. Despite great progress in perception, diagnosis and treatment of hypertension, blood pressure control is inadequate in less than half of the hypertensive patients (<140/90 mm Hg). The diagnosis of arterial hypertension starts in most patients with the conventional office blood pressure measurement...
May 29, 2017: Herz
https://www.readbyqxmd.com/read/28549461/the-effect-of-white-coats-and-gender-on-medical-students-perceptions-of-physicians
#14
Malika Ladha, Aleem Bharwani, Kevin McLaughlin, Henry T Stelfox, Adam Bass
BACKGROUND: Despite the fact that medical schools spend a considerable effort to rate clinical instructors, there is limited evidence regarding the effect of physical characteristics on instructor ratings. White coats have been shown to alter patients' perceptions of physicians although it has not been determined if preceptors who wear white coats are rated differently than their colleagues. METHODS: Second year medical students were administered a questionnaire with four clinical scenarios depicting medical errors accompanied by a picture of a physician of different sexes and ethnicities...
May 26, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28540180/hemoglobin-and-mean-platelet-volume-predicts-diffuse-t1-mri-white-matter-volume-decrease-in-sickle-cell-disease-patients
#15
Soyoung Choi, Adam M Bush, Matthew T Borzage, Anand A Joshi, William J Mack, Thomas D Coates, Richard M Leahy, John C Wood
Sickle cell disease (SCD) is a life-threatening genetic condition. Patients suffer from chronic systemic and cerebral vascular disease that leads to early and cumulative neurological damage. Few studies have quantified the effects of this disease on brain morphometry and even fewer efforts have been devoted to older patients despite the progressive nature of the disease. This study quantifies global and regional brain volumes in adolescent and young adult patients with SCD and racially matched controls with the aim of distinguishing between age related changes associated with normal brain maturation and damage from sickle cell disease...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28505180/empathic-nonverbal-behavior-increases-ratings-of-both-warmth-and-competence-in-a-medical-context
#16
Gordon T Kraft-Todd, Diego A Reinero, John M Kelley, Andrea S Heberlein, Lee Baer, Helen Riess
In medicine, it is critical that clinicians demonstrate both empathy (perceived as warmth) and competence. Perceptions of these qualities are often intuitive and are based on nonverbal behavior. Emphasizing both warmth and competence may prove problematic, however, because there is evidence that they are inversely related in other settings. We hypothesize that perceptions of physician competence will instead be positively correlated with perceptions of physician warmth and empathy, potentially due to changing conceptions of the physician's role...
2017: PloS One
https://www.readbyqxmd.com/read/28490105/a-novel-technology-for-the-rapid-selective-magnetic-removal-of-pathogenesis-related-proteins-from-wines
#17
Agnieszka Mierczynska-Vasilev, Pierre Boyer, Krasimir Vasilev, Paul A Smith
Haze formation is a significant problem for the wine industry. A novel technology for the rapid, selective, magnetic removal of pathogenesis-related proteins from wine was developed. The pathogenesis-related proteins in nine different white wines were selectively captured and removed by acrylic acid plasma-coated magnetic nanoparticles. Treated white wines were analyzed for protein and phenolic content to assess the performance of the functionalized magnetic nanoparticles. The analysis showed that the acrylic acid coated magnetic nanoparticles effectively removed proteins and did not significantly change the phenolic composition of the wines...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28475667/interarm-difference-in-systolic-blood-pressure-in-different-ethnic-groups-and-relationship-to-the-white-coat-effect-a-cross-sectional-study
#18
Claire Lorraine Schwartz, Christopher Clark, Constantinos Koshiaris, Paramjit S Gill, Shelia M Greenfield, Sayeed M Haque, Gurdip Heer, Amanpreet Johal, Ramandeep Kaur, Jonathan Mant, Una Martin, Mohamed A Mohammed, Sally Wood, Richard J McManus
BACKGROUND: Interarm differences (IADs) ≥10 mm Hg in systolic blood pressure (BP) are associated with greater incidence of cardiovascular disease. The effect of ethnicity and the white coat effect (WCE) on significant systolic IADs (ssIADs) are not well understood. METHODS: Differences in BP by ethnicity for different methods of BP measurement were examined in 770 people (300 White British, 241 South Asian, 229 African-Caribbean). Repeated clinic measurements were obtained simultaneously in the right and left arm using 2 BPTru monitors and comparisons made between the first reading, mean of second and third and mean of second to sixth readings for patients with, and without known hypertension...
May 5, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28470470/role-of-paced-breathing-for-treatment-of-hypertension
#19
REVIEW
Relu Cernes, Reuven Zimlichman
PURPOSE OF REVIEW: Hypertension remains to be a major contributor to global morbidity and mortality. Despite a plethora of pharmacological options available, an abundance of patients have uncontrolled blood pressure thus creating the need for additional strategies, including non-pharmacologic approaches. In this review, we discuss the antihypertensive effect of slow and deep respiration by increasing baroreflex sensitivity. RECENT FINDINGS: Asking patients to carry out paced breathing sessions unaccompanied by a personal coach or unaided by a device may be unfeasible...
June 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28424147/treatment-of-leukoencephalopathy-with-calcifications-and-cysts-with-bevacizumab
#20
Alex J Fay, Allison A King, Joshua S Shimony, Yanick J Crow, Jan E Brunstrom-Hernandez
BACKGROUND: Leukoencephalopathy with calcifications and cysts is a rare, autosomal recessive cerebral microangiopathy that causes progressive white matter disease, calcifications, and cysts within the brain. It is typically associated with slowly progressive psychomotor regression, seizures, and movement disorders. Although leukoencephalopathy with calcifications and cysts affects only the central nervous system, it demonstrates remarkable neuropathologic and radiologic overlap with Coats plus, a disorder of small vessels of the brain, eyes, gastrointestinal tract, and bone...
March 23, 2017: Pediatric Neurology
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