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White coat effect

Ricardo Lima Shintcovsk, Roberto Soares da Silva, Larry White, Lidia Parsekian Martins, Renato Parsekian Martins
OBJECTIVES: To evaluate if a 0.5-mm vertical bend applied on an incisor bracket produces movements in other planes and if different wires influence these effects. MATERIALS AND METHODS: An acrylic model of a treated patient with brackets passively bonded was attached to an Orthodontic Force Tester, and a load cell was attached to the left lateral incisor. Thirty 0.019 × 0.025-inch archwires were divided into three groups according to their alloy: SS (stainless steel), B-Ti (beta-titanium), and MF (beta-titanium wire coated with nickel-titanium)...
May 15, 2018: Angle Orthodontist
Max J Romano
In this essay, I reflect on some of the ways racial privilege influenced my experience as a white physician in training. While white Americans often think of "racism" as a social construct primarily affecting people of color, "racism" is a system of both racial disadvantage as well as reciprocal racial advantage. Medical professionals are increasingly aware of how social determinants of health lead to important health disparities, however white physicians seldom ask how their own racial privilege reinforces a white supremacist culture and what effects this may have on our patients' health...
May 2018: Annals of Family Medicine
Kanae Nakamura, Tsunao Kishida, Akika Ejima, Riho Tateyama, Satoru Morishita, Tomoji Ono, Michiaki Murakoshi, Keikichi Sugiyama, Hoyoku Nishino, Osam Mazda
Lactoferrin (LF) is a multifunctional protein in mammalian milk. We previously reported that enteric-coated bovine LF reduced the visceral fat in a double-blind clinical study. We further demonstrated that bovine LF (bLF) inhibited adipogenesis and promoted lipolysis in white adipocytes, but the effect of bLF on brown adipocytes has not been clarified. In this study, we investigated the effects of bLF on energy expenditure and cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) signaling pathway using human reprogrammed brown adipocytes generated by gene transduction...
May 9, 2018: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
Kara A Nerenberg, Kelly B Zarnke, Alexander A Leung, Kaberi Dasgupta, Sonia Butalia, Kerry McBrien, Kevin C Harris, Meranda Nakhla, Lyne Cloutier, Mark Gelfer, Maxime Lamarre-Cliche, Alain Milot, Peter Bolli, Guy Tremblay, Donna McLean, Raj S Padwal, Karen C Tran, Steven Grover, Simon W Rabkin, Gordon W Moe, Jonathan G Howlett, Patrice Lindsay, Michael D Hill, Mike Sharma, Thalia Field, Theodore H Wein, Ashkan Shoamanesh, George K Dresser, Pavel Hamet, Robert J Herman, Ellen Burgess, Steven E Gryn, Jean C Grégoire, Richard Lewanczuk, Luc Poirier, Tavis S Campbell, Ross D Feldman, Kim L Lavoie, Ross T Tsuyuki, George Honos, Ally P H Prebtani, Gregory Kline, Ernesto L Schiffrin, Andrew Don-Wauchope, Sheldon W Tobe, Richard E Gilbert, Lawrence A Leiter, Charlotte Jones, Vincent Woo, Robert A Hegele, Peter Selby, Andrew Pipe, Philip A McFarlane, Paul Oh, Milan Gupta, Simon L Bacon, Janusz Kaczorowski, Luc Trudeau, Norman R C Campbell, Swapnil Hiremath, Michael Roerecke, Joanne Arcand, Marcel Ruzicka, G V Ramesh Prasad, Michel Vallée, Cedric Edwards, Praveena Sivapalan, S Brian Penner, Anne Fournier, Geneviève Benoit, Janusz Feber, Janis Dionne, Laura A Magee, Alexander G Logan, Anne-Marie Côté, Evelyne Rey, Tabassum Firoz, Laura M Kuyper, Jonathan Y Gabor, Raymond R Townsend, Doreen M Rabi, Stella S Daskalopoulou
Hypertension Canada provides annually updated, evidence-based guidelines for the diagnosis, assessment, prevention, and treatment of hypertension in adults and children. This year, the adult and pediatric guidelines are combined in one document. The new 2018 pregnancy-specific hypertension guidelines are published separately. For 2018, 5 new guidelines are introduced, and 1 existing guideline on the blood pressure thresholds and targets in the setting of thrombolysis for acute ischemic stroke is revised. The use of validated wrist devices for the estimation of blood pressure in individuals with large arm circumference is now included...
May 2018: Canadian Journal of Cardiology
Soyoung Na, Jin-Hee Kim, Hye-Jin Jang, Hee Jung Park, Se-Wook Oh
In this study, we examined the effects of an ε-polylysine (PL) and chitosan (CH) coating on the quality of shrimp under refrigeration. Pacific white shrimp (Litopenaeus vannamei) were coated with PL, CH, or CH + PL and stored at 4 °C for 15 days. The quality of shrimp was measured by observing changes in microbiota, pH, total volatile basic nitrogen (TVB-N), and sensory characteristics. Among the coating films, the CH + PL coating most effectively inhibited the growth of mesophilic and psychrotrophic bacteria, Pseudomonas spp...
May 1, 2018: International Journal of Biological Macromolecules
Diana Ram, Maria Laura Hermida, Andrea Braun Jerozolimsky, Or-Yan Slav, Hao-Yu Wang, Florencia Puig Abbate, Ana Lorente Rodriguez, Cristina Cuadros-Fernández, Roberto Vofovics Leon, Esti Davidovich
BACKGROUND: Data are conflicting regarding the effect of professional staff attire on children at pediatric dental clinics. AIM: To compare the preferences of children and their parents in three countries, regarding the gender and attire of pediatric dentists. STUDY DESIGN: A multi-centered study was conducted in pediatric dental clinics in Israel (N=100), Uruguay (N=270) and Spain (N=200). Children, aged 4-12 years, and their parents were asked to choose the pediatric dentist they preferred from 5 pictures of the same male and 5 pictures of the same female, in different attire...
April 26, 2018: Journal of Clinical Pediatric Dentistry
Vincent Offermanns, Otto Steinmassl, Ole Z Andersen, Christian S Jeppesen, Søren Sørensen, Heribert Talasz, Herbert H Lindner, Morten Foss, Frank Kloss
BACKGROUND: Studies have shown that strontium comprising medical devices affirmatory contribute to bone healing and osseointegration. The aim of this study was to evaluate the in vivo performance of surface-functionalized implants (Ti-Sr-O), showing predictable release characteristics of strontium and compare it to a commercially available fluoride-modified surface. METHODS: Ti-Sr-O functionalized, fluoride-modified and Grade 4 titanium implants were inserted in the femoral condyle of adult male New Zealand White rabbits...
April 26, 2018: Journal of Periodontology
P Neville, L McNally, A Waylen
INTRODUCTION: The UK General Dental Council stipulates that professionalism is a key aspect of the teaching and training of dental students. However, dental educators highlight that teaching dental student's professionalism can be challenging and students often rate this teaching activity negatively. This article documents a teaching initiative at one UK Dental School that aimed to strengthen the professionalism curriculum by introducing a Dental Scrubs Ceremony for second-year students...
April 13, 2018: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
Hao Xu, Cui-Cui Guo, Zheng-Yu Gao, Chang-Yao Wang, Hai-Ning Zhang, Cheng-Yu Lv, Zi-Yan Yin, Ying-Zhen Wang
Wear debris induced aseptic loosening is the leading cause of total knee arthroplasty (TKA) failure. The complex mechanism of aseptic loosening has been a major issue for introducing effective prevention and treatment methods, so a simplified yet efficient rabbit model was established to address this concern with the use of micrometer-sized titanium particles. 20 New Zealand white rabbits were selected and divided into two groups (control = 10, study = 10). A TKA surgery was then performed for each of them, with implantation of a titanium rod prosthesis which was coated evenly with micrometer-sized titanium in the study group and nothing in the control group, into right femoral medullary cavity...
2018: BioMed Research International
Dimitra Aslanidou, Ioannis Karapanagiotis, Dimitrios Lampakis
Silica nanoparticles were dispersed in an aqueous emulsion of alkoxy silanes and organic fluoropolymer. The dispersion was sprayed onto white marble and sandstone. The deposited composite coatings exhibited (i) superhydrophobicity and superoleophobicity, as evidenced by the high (>150°) static contact angles of water and oil drops as well as (ii) water and oil repellency according to the low (<7°) corresponding tilt contact angles. Apart from marble and sandstone, the coatings with extreme wetting properties were deposited onto concrete, silk, and paper, thus demonstrating the versatility of the method...
April 10, 2018: Materials
Emmanuel A Andreadis, Charalampia V Geladari, Epameinondas T Angelopoulos, Florentia S Savva, Anna I Georgantoni, Vasilios Papademetriou
BACKGROUND: Automated office blood pressure (AOBP) measurement is superior to conventional office blood pressure (OBP) because it eliminates the "white coat effect" and shows a strong association with ambulatory blood pressure. METHODS AND RESULTS: We conducted a cross-sectional study in 146 participants with office hypertension, and we compared AOBP readings, taken with or without the presence of study personnel, before and after the conventional office readings to determine whether their variation in blood pressure showed a difference in blood pressure values...
April 7, 2018: Journal of the American Heart Association
Martin G Myers
Manual blood pressure (BP) recorded in routine clinical practice is relatively inaccurate and associated with higher readings compared to BP measured in research studies in accordance with standardized measurement guidelines. The increase in routine office BP is the result of several factors, especially the presence of office staff, which tends to make patients nervous and also allows for conversation to occur. With the disappearance of the mercury sphygmomanometer because of environmental concerns, there is greater use of oscillometric BP recorders, both in the office setting and elsewhere...
April 2018: Korean Circulation Journal
Peng Wang, Rianne P Gorter, Jenny C de Jonge, Muhammad Nazmuddin, Chao Zhao, Sandra Amor, Dick Hoekstra, Wia Baron
Upon demyelination, transient expression of fibronectin precedes successful remyelination. However, in chronic demyelination observed in multiple sclerosis (MS), aggregates of fibronectin persist and contribute to remyelination failure. Accordingly, removing fibronectin (aggregates) would constitute an effective strategy for promoting remyelination. Matrix metalloproteinases (MMPs) are enzymes known to remodel extracellular matrix components, including fibronectin. Here, we examined the ability of MMPs to degrade fibronectin aggregates...
March 30, 2018: Glia
Richard Mayne, James Whiting, Andrew Adamatzky
The nanotechnology revolution has allowed us to speculate on the possibility of hybridising nanoscale materials with live substrates, yet significant doubt still remains pertaining to the effects of nanomaterials on biological matter. In this investigation, we cultivate the ciliated protistic pond-dwelling microorganism Paramecium caudatum in the presence of excessive quantities of magnetite nanoparticles in order to deduce potential beneficial applications for this technique, as well as observe any deleterious effects on the organisms' health...
2018: BioNanoScience
Luciana K Rosselli-Murai, Joel A Yates, Sei Yoshida, Julia Bourg, Kenneth K Y Ho, Megan White, Julia Prisby, Xinyu Tan, Megan Altemus, Liwei Bao, Zhi-Fen Wu, Sarah Veatch, Joel Swanson, Sofia Merajver, Allen P Liu
Defective endocytosis and vesicular trafficking of signaling receptors has recently emerged as a multifaceted hallmark of malignant cells. Clathrin-coated pits (CCPs) display highly heterogeneous dynamics on the plasma membrane where they can take from 20 seconds to over a minute to form cytosolic coated-vesicles. Despite the large number of cargo molecules that traffic through CCPs, it is not well understood whether signaling receptors activated in cancer, such as epidermal growth factor receptor (EGFR), are regulated through a specific subset of CCPs...
March 27, 2018: Journal of Cell Science
Zheqin Liu, Yongqiang Zhang, Yi Fan, Zhenqiang Chen, Zhaobing Tang, Jialong Zhao, Ying Lv, Jie Lin, Xiaoyang Guo, Jiahua Zhang, Xingyuan Liu
Methylammonium (MA) lead halide (MAPbX3, X=Cl, Br, I) perovskite quantum dots (PQDs) are very sensitive to environment (moisture, oxygen and temperature), suffering from poor stability. In order to improve the stability, silica coated PQDs (SPQDs) were synthesized by an improved ligand-assisted reprecipitation method through simply mixing and stirring under room temperature in air without adding water and catalyst, the whole process took only a few seconds. The photoluminescence (PL) spectra of the SPQDs can be tuned continuously from 460 nm to 662 nm via adjusting the composition proportion of precursors...
March 27, 2018: ACS Applied Materials & Interfaces
Jitka Seidlerová, Julius Gelžinský, Markéta Mateřánková, Jiří Ceral, Petr König, Jan Filipovský
AIMS: Several papers reported that unattended automated office blood pressure (uAutoOBP) is closely related to daytime ambulatory blood pressure monitoring (ABPM). In the present study, we aim to study uAutoOBP and its relation to 24-hour ABPM and ABPM variability. MATERIAL AND METHODS: Stable treated hypertensive subjects were examined in two Czech academic hypertension centres. uAutoOBP was measured with the BP Tru device; attended BP three times with auscultatory method (AuscOBP) by the physician...
March 22, 2018: Blood Pressure
Elena Boldo, Adela Castelló, Nuria Aragonés, Pilar Amiano, Beatriz Pérez-Gómez, Gemma Castaño-Vinyals, Vicente Martín, Marcela Guevara, Carmen Urtiaga, Trinidad Dierssen-Sotos, Guillermo Fernández-Tardón, Victor Moreno, Marta Solans, Rosanna Peiró, Rocio Capelo, Inés Gómez-Acebo, Jesús Castilla, Antonio José Molina, Xavier Castells, Jone M Altzibar, Virginia Lope, Manolis Kogevinas, Isabelle Romieu, Marina Pollán
OBJECTIVE: To analyse the relationship of the risk of breast cancer (BC) to meat intake, preference regarding degree of cooking ('doneness') and cooking methods, using data from a population-based case-control study (MCC-Spain). STUDY DESIGN: 1006 Histologically confirmed incident BC cases and 1370 controls were recruited in 10 Spanish provinces. Participants were 23-85 years old. They answered an epidemiological survey and a food frequency questionnaire. BC risk was assessed overall, by menopausal status and by pathological subtypes, using logistic and multinomial regression mixed models adjusted for known confounding factors and including province as a random effects term...
April 2018: Maturitas
Akanksha Bhatnagar, Ulrich Pein, Silke Markau, Karl Weigand, Paolo Fornara, Matthias Girndt, Eric Seibert
BACKGROUND/AIMS: We compare conventional office blood pressure measurements with automated SPRINT-study type readings in kidney transplant recipients in order to determine the impact of the white coat effect in a prospective observational study. METHODS: Adult patients with a functional renal transplant not dependent on dialysis were eligible. Readings were taken in the office in presence of the physician with an oscillometric method. Afterwards, readings were repeated with the patients resting alone in a quiet examination room with an automated blood pressure monitor...
March 6, 2018: Kidney & Blood Pressure Research
Mehran Abolbashari
PURPOSE OF REVIEW: This review aims to clarify the cardiovascular risk of white coat hypertension (WCH). RECENT FINDINGS: Cardiovascular risk of WCH has been evaluated in multiple meta-analyses and population-based studies. International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes study evaluated the cardiovascular risk in 653 patients with WCH and 5137 normotensive patients. The patients were age-matched and were followed for 10...
March 8, 2018: Current Cardiology Reports
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