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White coat effect

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https://www.readbyqxmd.com/read/28424147/treatment-of-leukoencephalopathy-with-calcifications-and-cysts-with-bevacizumab
#1
Alex J Fay, Allison A King, Joshua S Shimony, Yanick J Crow, Jan E Brunstrom-Hernandez
BACKGROUND: Leukoencephalopathy with calcifications and cysts is a rare, autosomal recessive cerebral microangiopathy that causes progressive white matter disease, calcifications, and cysts within the brain. It is typically associated with slowly progressive psychomotor regression, seizures, and movement disorders. Although leukoencephalopathy with calcifications and cysts affects only the central nervous system, it demonstrates remarkable neuropathologic and radiologic overlap with Coats plus, a disorder of small vessels of the brain, eyes, gastrointestinal tract, and bone...
March 23, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28415391/biological-activity-evaluation-of-magnesium-fluoride-coated-mg-zn-zr-alloy-in-vivo
#2
Hongfeng Jiang, Jingbo Wang, Minfang Chen, Debao Liu
AIM: To explore the biodegradable characteristics and biological properties, which could promote new bone formation, of MgF2 coated magnesium alloy (Mg-3wt%Zn-0.5wt%Zr) in rabbits. METHODS: Magnesium alloy with MgF2 coating was made and the MgF2/Mg-Zn-Zr was implanted in the femoral condyle of rabbits. Twelve healthy adult Japanese white rabbits in weight of 2.8-3.2kg were averagely divided into A(Mg-Zn-Zr) group and B(MgF2/MgZn-Zr) group. Indexes such as microstructural evolution, SEM scan, X-ray, Micro-CT and mechanical properties were observed and detected at 1th day, 2th, 4th, 8th, 12th, 24th week after implantation...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28406393/is-medical-environment-detrimental-to-memory-a-test-of-a-white-coat-effect-on-older-people-s-memory-performance
#3
Morgane Schlemmer, Olivier Desrichard
OBJECTIVES: Test if older people's memory assessment may be impacted by a medical environment and if memory self-efficacy (MSE) will moderate this effect. METHODS: We evaluated memory performance and MSE in 27 older adults in two different settings: a (control) university research environment, or a (proxy-medical) neuropsychological examination environment. RESULTS: The results showed a MSE × environment interaction effect on story-recall performance, with older people with low MSE performing less well in the proxy-medical situation than in the control situation and with elders with high MSE performing better in the proxy-medical situation than in the control situation...
March 27, 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28396086/polymer-modified-fibrous-mesoporous-silica-nanoparticles-as-coating-material-for-open-tubular-capillary-electrochromatography
#4
Yuanyuan Liu, Qing Liu, Haiyan Yu, Shujun Sun, Yun Xue, Yan Wang, Qishu Qu, Chao Yan
A novel fibrous mesoporous silica nanoparticles (fSiO2) stationary phase grafted with polymer (Poly (2-(dimethylamino) ethyl methacrylate) (PDMAEMA) was developed for open tubular capillary electrochromatography (OT-CEC). The preparation procedure included synthesizing fSiO2 through biphase stratification approach, removing the surfactants, silanization and in situ graft polymerization with monomers via atom transfer radical polymerization (ATRP). Subsequently, PDMAEMA-modified mesoporous silica nanoparticles (P-fSiO2)/ethanol solution was immobilized onto the inner surface of the pretreated capillary and functionalized with octadecylsilane to fabricate the open-tubular column...
March 28, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28380975/direct-evidence-of-visible-surface-plasmon-excitation-in-ito-film-coated-on-linbo-sub-3-sub-slabs
#5
Hua Zhao, Yince Wang, Tingyu Xue, Hang Su, Jingwen Zhang
An iron-doped Y-cut lithium niobate (Fe:LN) slab was coated with indium-tin-oxide (ITO) thin films by magnetron sputtering. The electron confinement in a sub-nanometer region at ITO/LN interfaces is resulted from electric screening effect. Consequently, the local plasma frequency in the sub-nanometer metallic-like layer is shifted to the UV regime. This makes it possible to excite surface plasmon polaritons (SPPs) in the visible region with photorefractive phase gratings in the LN slab and to transport SPPs much energy-efficiently...
March 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28380539/the-larson-blue-coat-color-phenotype-in-holsteins-characteristics-and-effects-on-body-temperature-regulation-and-production-in-lactating-cows-in-a-hot-climate
#6
S Dikmen, G E Dahl, J B Cole, D J Null, P J Hansen
Here we report a previously undescribed coat color phenotype in Holstein cattle. Larson Blue Holsteins, located on a dairy in south Florida, exhibit a coloration pattern that is similar to that of black and white or red and white Holsteins except that, instead of being black or red, darker regions of the body vary in color from gray to taupe. The Larson Blue phenotype was readily apparent in young calves. The phenotype is not due to inheritance of known mutations causing coat color variation in cattle, including dominant red, Telstar, silver color dilutor, or Dun color...
March 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28367582/the-auxiliary-white-coat-effect-in-hospitals-perceptions-of-patients-and-doctors
#7
Kor Woi Tiang, Azad Hassan Abdul Razack, Keng Lim Ng
A doctor's attire is vital for both a positive first impression and the overall healthcare experience of patients. We attempted to understand patients' and doctors' perceptions and preferences regarding six types of dress codes used by doctors in different situations and locations. A total of 87 patients and 46 doctors participated in the study. Separate sets of questionnaires, that included four demographic questions and 14 survey questions, were given to the patient and doctor groups. Most patients preferred doctors dressed formally in white coats irrespective of scenarios or locations whereas majority of doctors preferred formal attire without white coats...
April 3, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28367031/surgical-management-of-chronic-hyperplastic-candidiasis-refractory-to-systemic-antifungal-treatment
#8
Neha Shah, Jay Gopal Ray, Sanchita Kundu, Divesh Sardana
Chronic hyperplastic candidiasis (CHC), earlier known as candidal leukoplakia, is a variant of oral candidiasis that classically presents as a white patch on the commissures of the oral mucosa and it is mostly caused by Candida albicans. Clinically, the lesions are usually asymptomatic and regress after appropriate antifungal therapy and correction of the underlying cause. If the lesions are untreated, a small portion may develop dysplasia and later progress into carcinoma. The purpose of this article is to report a case of CHC in a 57-year-old male patient with a significant smoking habit, who presented with a thick, nonscrapable, brownish-white coating on the dorsum of the tongue for 9 years...
April 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28363020/highly-efficient-blue-emitting-cdse-derived-core-shell-gradient-alloy-quantum-dots-with-improved-photoluminescent-quantum-yield-and-enhanced-photostability
#9
Junsang Cho, Yun Ku Jung, Jin-Kyu Lee, Hak-Sung Jung
Highly efficient blue-emitting CdSe-derived core/shell gradient alloy quantum dots (CSGA QDs) with photoluminescence quantum yield (PL QY) of ca. 90% have been synthesized through a facile "one-pot" approach. CdSe nuclei are initially formed as core and gradient alloy shells such as CdSexS1-x/ZnSeyS1-y simultaneously encapsulate the preformed CdSe core in an energy-gradient fashion eventually followed by coating with ZnS shells due to the faster precursor reaction kinetics of Cd and Se compared to analog of Zn and S...
April 6, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28352632/decoding-white-coat-hypertension
#10
REVIEW
Dennis A Bloomfield, Alex Park
There is arguably no less understood or more intriguing problem in hypertension that the "white coat" condition, the standard concept of which is significantly blood pressure reading obtained by medical personnel of authoritative standing than that obtained by more junior and less authoritative personnel and by the patients themselves. Using hospital-initiated ambulatory blood pressure monitoring, the while effect manifests as initial and ending pressure elevations, and, in treated patients, a low daytime profile...
March 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28341174/insights-into-the-mechanism-of-how-morin-suppresses-amyloid-fibrillation-of-hen-egg-white-lysozyme
#11
Xiaoying Chong, Luchen Sun, Yonghui Sun, Lin Chang, Alan K Chang, Xian Lu, Xuejie Zhou, Junqing Liu, Bing Zhang, Gary W Jones, Jianwei He
This communication describes the inhibitory effect of Morin on the fibrillation of Hen Egg White Lysozyme (HEWL), a generic amyloid-forming model protein. This effect was dose-dependent and stronger than other small molecules we have tested previously. Spectrofluorometric and computational studies support a model suggesting that Morin inhibits amyloid fibril formation of HEWL by binding to the aggregation prone cleft region of the β-domain of HEWL, thereby stabilizing the molecule in its native-like state...
March 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28319188/reduced-performance-of-a-pvc-coated-biogents-sentinel-prototype-in-comparison-to-the-original-biogents-sentinel-for-monitoring-the-asian-tiger-mosquito-aedes-albopictus-in-temperate-north-america
#12
Isik Unlu, Ary Faraji, Michael Morganti, Randy Vaeth, Karen Akaratovic, Jay Kiser, Charles Abadam, Dan Kline
Aedes albopictus is a major nuisance pest and also a public health concern because of the role it plays in the transmission of arboviruses. There is a continuing demand for effective surveillance tools for this species. The first generation of Biogents Sentinel (BGS1) traps have proven to be an effective tool for surveillance of Ae. albopictus throughout its range, however, some defects in construction led to the eventual development of the next generation. We compared the performance of the new generation prototype trap (BGS2P) to the original...
2017: PloS One
https://www.readbyqxmd.com/read/28306636/blood-pressure-lowering-efficacy-and-safety-of-perindopril-indapamide-amlodipine-single-pill-combination-in-patients-with-uncontrolled-essential-hypertension-a-multicenter-randomized-double-blind-controlled-trial
#13
Jean-Jacques Mourad, Celso Amodeo, Martine de Champvallins, Romualda Brzozowska-Villatte, Roland Asmar
OBJECTIVES: This 4-month, double-blind, randomized, controlled trial was designed to demonstrate the superiority of perindopril/indapamide/amlodipine single pill over perindopril/indapamide after 1 month and to determine further up-titration efficacy and safety in patients with mild-to-moderate hypertension. METHODS: After a 1-month run-in period on perindopril/indapamide 5/1.25 mg, patients with SBP/DBP at least 150/95 mmHg and no diabetes or renal insufficiency received perindopril/indapamide/amlodipine 5/1...
March 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28303535/hyaluronic-acid-based-hydrogel-coating-does-not-affect-bone-apposition-at-the-implant-surface-in-a-rabbit-model
#14
W Boot, D Gawlitta, P G J Nikkels, B Pouran, M H P van Rijen, W J A Dhert, H Ch Vogely
BACKGROUND: Uncemented orthopaedic implants rely on the bone-implant interface to provide stability, therefore it is essential that a coating does not interfere with the bone-forming processes occurring at the implant interface. In addition, local application of high concentrations of antibiotics for prophylaxis or treatment of infection may be toxic for osteoblasts and could impair bone growth. QUESTIONS/PURPOSES: In this animal study, we investigated the effect of a commercially available hydrogel, either unloaded or loaded with 2% vancomycin...
March 16, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28301136/broadband-omnidirectional-light-trapping-in-gold-decorated-zno-nanopillar-arrays
#15
Yuan-Ming Chang, Man-Ling Lin, Tung-Yen Lai, Chang-Hung Chen, Hsin-Yi Lee, Chih-Ming Lin, Yew-Chung Sermon Wu, Yen-Fu Lin, Jenh-Yih Juang
The photoluminescence (PL) and reflectivity characteristics of zinc oxide nanopillars (ZnO-NPs) grown on indium-tin-oxide (ITO)-coated glasses were investigated. The room temperature PL showed bright white-light emission for the undoped ZnO-NPs grown at 600 °C, suggesting the close relation between the optical characteristic and the growth conditions being carried out for obtaining the present ZnO-NPs. The reflectivity of the as-grown ZnO-NPs array was about ∼29% with the wavelength of the incident light ranging from 200 to 1800 nm...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28295530/the-fanny-pack-no-ifs-ands-or-buts
#16
Kaiane Habeshian, Anna Yasmine Kirkorian, Kalyani Marathe
Although the white coat is central to the practice of adult medicine, pediatricians often shed it to avoid creating negative associations and provoking fear in children. In our pediatric dermatology practice, the fanny pack (FP) has replaced many of the functional elements of the white coat. The FP is a kid-friendly way to readily carry key medical supplies from one patient encounter to the next. It is more hygienic, light weight, and affordable than traditional doctor's bags and white coats. In this article we outline the benefits of the FP, which include storage, ergonomics, efficiency, cleanliness, kid-friendliness, and cost-effectiveness...
March 10, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28266276/alerting-reaction-in-office-blood-pressure-and-target-organ-damage-an-innocent-phenomenon
#17
Jessica Barochiner, Lucas S Aparicio, Jose Alfie, Paula E Cuffaro, Marcos J Marin, Margarita S Morales, Marcelo Rada, Gabriel D Waisman
BACKGROUND: An alerting reaction is a physician-induced phenomenon which produces a transient blood pressure rise in the office. OBJECTIVE: To determine its relationship with target organ damage in treated hypertensives. METHOD: We used three different indexes for calculating alerting reaction depending on the first, second or third office blood pressure measurement. We correlated these indexes with glomerular filtration rate, left ventricular mass index and pulse wave velocity...
March 6, 2017: Current Hypertension Reviews
https://www.readbyqxmd.com/read/28245111/simplifying-nucleic-acid-amplification-from-whole-blood-with-direct-polymerase-chain-reaction-on-chitosan-microparticles
#18
Imaly A Nanayakkara, Weidong Cao, Ian M White
Tremendous advances have been made in the development of portable nucleic acid amplification devices for near-patient use. However, the true limitation in the realization of nucleic acid amplification tests (NAATs) for near-patient applications is not the amplification reaction, it is the complexity of the sample preparation. Conventional approaches require several precise intervention steps during the protocol. There are numerous reports in the literature that mimic the sample preparation procedure within a lab-on-a-chip device or cartridge, but these systems require a high number of integrated steps, making the devices and/or their supporting equipment too complex to meet the necessary cost targets and regulatory requirements for near-patient applications...
March 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28199121/smart-contact-lenses-with-graphene-coating-for-electromagnetic-interference-shielding-and-dehydration-protection
#19
Sangkyu Lee, Insu Jo, Sangmin Kang, Bongchul Jang, Joonhee Moon, Jong Bo Park, Soochang Lee, Sichul Rho, Youngsoo Kim, Byung Hee Hong
Recently, smart contact lenses with electronic circuits have been proposed for various sensor and display applications where the use of flexible and biologically stable electrode materials is essential. Graphene is an atomically thin carbon material with a two-dimensional hexagonal lattice that shows outstanding electrical and mechanical properties as well as excellent biocompatibility. In addition, graphene is capable of protecting eyes from electromagnectic (EM) waves that may cause eye diseases such as cataracts...
February 21, 2017: ACS Nano
https://www.readbyqxmd.com/read/28185453/modification-of-the-highly-conductive-pedot-pss-layer-for-use-in-silver-nanogrid-electrodes-for-flexible-inverted-polymer-solar-cells
#20
Jie Wang, Fei Fei, Qun Luo, Shuhong Nie, Na Wu, Xiaolian Chen, Wenming Su, Yuanjie Li, Chang-Qi Ma
Silver nanogrid based flexible transparent electrode is recognized as the most promising alternative to ITO electrode for organic electronics, owing to its low production cost and excellent flexibility. Typically, a highly conductive thin film coating layer, such as highly conductive PEDOT:PSS (HC-PEDOT:PSS) is usually deposited onto the Ag-grid electrode to smooth the surface and to minimize the sheet resistance. In this paper, we found that inverted flexible polymer solar cells with structure of Ag-grid/HC-PEDOT:PSS/ZnO/photoactive layer/MoO3/Al generally exhibits strong S-shaped J-V curves, which could be eliminated by light-soaking treatment...
March 1, 2017: ACS Applied Materials & Interfaces
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