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https://www.readbyqxmd.com/read/28984615/initiation-of-levodopa-carbidopa-intestinal%C3%A2-gel-infusion-using-telemedicine-video-communication-system-facilitates-efficient-and-well-accepted-home-titration%C3%A2-in-patients-with-advanced-parkinson-s-disease
#1
Thomas Willows, Nil Dizdar, Dag Nyholm, Håkan Widner, Peter Grenholm, Ursula Schmiauke, Anna Urbom, Kristina Groth, Jörgen Larsson, Johan Permert, Susanna Kjellander
BACKGROUND: Levodopa-carbidopa intestinal gel (LCIG; Duodopa ®) is used for continuous infusion in advanced Parkinson's disease. To achieve optimal effect, the LCIG dose is individually titrated, traditionally conducted during hospitalization in Sweden. However, dose adjustment depends on surrounding conditions, physical activity, and emotional stress, which is why titration at home could be beneficial. Telemedicine (TM) using a video communication system offers alternative titration procedures, allowing LCIG initiation at home...
October 4, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28961712/vedolizumab-levels-in-breast-milk-of-nursing-mothers-with-inflammatory-bowel-disease
#2
Adi Lahat, Ariella Bar-Gil Shitrit, Timna Naftali, Yael Milgrom, Rami Elyakim, Eran Goldin, Nina Levhar, Limor Selinger, Tzufit Zuker, Ella Fudim, Orit Picard, Miri Yavzori, Shomron Ben-Horin
Introduction: There are no data on the transfer of vedolizumab in breast milk of nursing mothers. We aimed to assess the presence of vedolizumab in breast milk of nursing inflammatory bowel disease (IBD) patients. Methods: This was a prospective observational study of vedolizumab-treated breast-feeding patients with IBD. Serum and breast milk samples were obtained at pre-defined time-points. The in-house developed ELISA assay for measuring vedolizumab in blood was adapted and validated for measurement of drug in breast milk...
August 31, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28947526/management-of-amiodarone-extravasation-with-intradermal-hyaluronidase
#3
Ashley N Fox, Ruben Villanueva, Jamie L Miller
PURPOSE: The case of a patient who experienced extravasation while receiving amiodarone via a peripheral infusion and was treated with intradermal hyaluronidase is reported. SUMMARY: A 60-year-old Caucasian man arrived at the emergency department after a motor vehicle collision. The patient was noted to have a subdural hematoma, multiple rib fractures, sternal body fracture, abdominal wall injury, left clavicle fracture, right humerus fracture, and vertebral fractures...
October 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28945709/energy-through-motion-an-activity-intervention-for-cancer-related-fatigue-in-an-ambulatory-infusion-center%C3%A2
#4
Linda Abbott, Mary Catherine Hooke
BACKGROUND: Cancer-related fatigue (CRF) occurs in most people with cancer undergoing chemotherapy. Physical activity (PA) is safe and effective in reducing CRF in people with cancer. 
. OBJECTIVES: This project involved the implementation and evaluation of a three-month PA program to maintain or improve CRF and quality of life.
. METHODS: Activity trackers and resistance bands were provided to participants. Verbal instruction, printed material, activity videos, and text messages were used in this program...
October 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28934894/factors-associated-with-unplanned-extubation-in-children-a-case-control-study
#5
Paulo Sérgio Lucas da Silva, Marcelo Cunio Machado Fonseca
PURPOSE: Although several studies assess unplanned extubation (UE) in children, few have addressed determinants of UE and factors associated with reintubation in a case-controlled manner. We aimed to identify the risk factors and outcomes associated with UE in a pediatric intensive care unit. METHODS: Cases of UE were randomly matched with control patients at a ratio of 1:4 for age, severity of illness, and admission diagnosis. For cases and controls, we also collected data associated with UE events, reintubation, and outcomes...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28910238/telemanagement-of-heart-failure-patients-across-the-post-acute-care-continuum
#6
Amy Dadosky, Heather Overbeck, Laura Barbetta, Ken Bertke, Maureen Corl, Kathleen Daly, Natasha Hiles, Nancy Rector, Eugene Chung, Santosh Menon
BACKGROUND: Heart failure (HF) is a chronic condition causing nearly 1 million hospital admissions annually in the United States with 25% of patients rehospitalized within 30 days. INTRODUCTION: The purpose of this study was to investigate whether telemanagement of HF patients throughout the post-acute continuum of care would reduce rehospitalization rates and improve patient self-care knowledge and satisfaction. MATERIALS AND METHODS: HF patients discharged to a skilled nursing facility (SNF) received telemanagement by HF clinicians with opportunity for continuation at home with assistance of home healthcare (HHC) nurses...
September 13, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28899265/enhancing-telehealth-education-in-nursing-applying-king-s-conceptual-framework-and-theory-of-goal-attainment
#7
Ann E Fronczek, Nicole A Rouhana, Judy M Kitchin
Telehealth technologies are increasingly used in the provision of nursing care to clients and populations. The education of nurses must include content and practice with telehealth technologies. The authors of this article discuss how one school of nursing has infused telehealth content and resources into undergraduate and graduate curricula using King's conceptual system and theory of goal attainment as a guide.
July 2017: Nursing Science Quarterly
https://www.readbyqxmd.com/read/28885479/high-dose-subcutaneous-immunoglobulin-in-patients-with-multifocal-motor-neuropathy-a-nursing-perspective
#8
Vilija M Rasutis, Hans D Katzberg, Vera Bril
Multifocal motor neuropathy (MMN), an immune neuromuscular condition causing progressive weakness, usually responds to immune-mediated treatments, including intravenous immunoglobulin (IVIG). Fifteen patients with MMN receiving IVIG were enrolled in an open-label, single-center trial and switched to 20% subcutaneous immunoglobulin (SCIG) using a smooth transition protocol (ie, changing the therapy without interruption or impact on the intended outcome of the therapy). Patients received individualized training and support based on motivation and ability to learn, follow directions, and maintain compliance...
September 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/28885476/determining-the-risk-of-sepsis-using-nurse-compounded-elastomeric-pumps-for-continuous-infusion-in-outpatient-parenteral-antibiotic-therapy
#9
Pauline M Dobson, Mark Loewenthal, Lisa Harris
Limited availability of compounded antibiotics used for continuous infusion outpatient parenteral antibiotic therapy (OPAT) can delay or interrupt an OPAT course. To solve this problem, OPAT nurses at a hospital in Australia have been compounding elastomeric pumps for immediate use. The incidence of sepsis in 5014 patients before and after the introduction of nurse compounding was compared. There were no cases of laboratory-confirmed bloodstream infection among the nurse-compounded group compared with 2 cases (0...
September 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/28885473/ins-2017-infusion-nursing-grand-rounds
#10
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://www.readbyqxmd.com/read/28876506/bisphosphonate-therapy-and-osteogenesis-imperfecta-the-lived-experience-of-children-and-their-mothers
#11
Shirley Wiggins, Rose Kreikemeier
PURPOSE: Osteogenesis imperfecta (OI) is a chronic, genetic condition frequently described as "brittle bones." This condition is expressed by low bone density and characterized by frequent fractures with and without trauma. Additional symptoms include pain, altered growth, and challenges with mobility. This experience has a great impact on the daily life of the child diagnosed with OI and their family. With the introduction of bisphosphonate therapy children diagnosed with OI experienced an increase in bone density that included a change in symptoms and improvement in daily functioning...
September 6, 2017: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/28857619/evaluation-of-the-performance-of-elastomeric-pumps-in-practice-are-we-under-delivering-on-chemotherapy-treatments
#12
Dahlia Salman, Jurga Biliune, Reem Kayyali, Jane Ashton, Peter Brown, Tim McCarthy, Elin Vikman, Stephen Barton, Julian Swinden, Shereen Nabhani-Gebara
Intro & aims: Elastomeric pumps are widely used to facilitate ambulatory chemotherapy, and studies have shown that they are safe and well received by patients. Despite these advantages, their end of infusion time can fluctuate significantly. The aim of this research was to observe the performance of these pumps in real practice and to evaluate patients' satisfaction. METHODS: This was a two-phase study conducted at three cancer units over 6 months. Phase-1 was an observational study recording the status of pumps at the scheduled disconnection time and noting remaining volume of infusion...
August 31, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28830854/a-mobile-device-app-to-reduce-medication-errors-and-time-to-drug-delivery-during-pediatric-cardiopulmonary-resuscitation-study-protocol-of-a-multicenter-randomized-controlled-crossover-trial
#13
Johan N Siebert, Frederic Ehrler, Christian Lovis, Christophe Combescure, Kevin Haddad, Alain Gervaix, Sergio Manzano
BACKGROUND: During pediatric cardiopulmonary resuscitation (CPR), vasoactive drug preparation for continuous infusions is complex and time-consuming. The need for individual specific weight-based drug dose calculation and preparation places children at higher risk than adults for medication errors. Following an evidence-based and ergonomic driven approach, we developed a mobile device app called Pediatric Accurate Medication in Emergency Situations (PedAMINES), intended to guide caregivers step-by-step from preparation to delivery of drugs requiring continuous infusion...
August 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28812473/implementation-of-a-pathway-for-the-treatment-of-fever-and-neutropenia-in-pediatric-patients-with-cancer
#14
Joy Vanderway, Catherine Vincent, Susan M Walsh, Jennifer Obrecht
Fever and neutropenia is an oncologic emergency. Time-to-antibiotics (TTA) refers to the amount of time from initial provider evaluation for fever and neutropenia to intravenous antibiotic administration. Research supports that rapid time-to-antibiotics (RTTA) is associated with improved patient outcomes. This quality improvement project evaluated the success of implementing an RTTA pathway in pediatric oncology patients with fever and neutropenia. The setting was an advanced practice nurse-managed pediatric ambulatory infusion center where patients with fever and neutropenia were often evaluated and treated...
September 2017: Journal of Pediatric Oncology Nursing: Official Journal of the Association of Pediatric Oncology Nurses
https://www.readbyqxmd.com/read/28800617/improved-usability-of-a-multi-infusion-setup-using-a-centralized-control-interface-a-task-based-usability-test
#15
Frank Doesburg, Fokie Cnossen, Willem Dieperink, Wouter Bult, Anne Marie de Smet, Daan J Touw, Maarten W Nijsten
The objective of this study was to assess the usability benefits of adding a bedside central control interface that controls all intravenous (IV) infusion pumps compared to the conventional individual control of multiple infusion pumps. Eighteen dedicated ICU nurses volunteered in a between-subjects task-based usability test. A newly developed central control interface was compared to conventional control of multiple infusion pumps in a simulated ICU setting. Task execution time, clicks, errors and questionnaire responses were evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/28790256/-safe-handling-of-hazardous-drugs-in-nursing-practice
#16
Kazue Hirai
Handling of hazardous drugs in nursing practice, there are risks of a wide variety of occupational exposures such as drug administration, management of spills, care of patients after administration, etc. Using a general infusion set for intravenous administration, there are risk of exposure such as scattering when the bottle needle is spiked into the infusion bag, leakage when priming the infusion line with antineoplastic drug, spillage when removing the side tube. For intravenous administration, use of CSTD for administration is most effective, but in many facilities, a general infusion set is used due to cost considerations...
July 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28770545/how-to-reduce-cisatracurium-consumption-in-ards-patients-the-tof-ards-study
#17
Sami Hraiech, Jean-Marie Forel, Christophe Guervilly, Romain Rambaud, Samuel Lehingue, Mélanie Adda, Pierre Sylla, Sabine Valera, Julien Carvelli, Marc Gainnier, Laurent Papazian, Jérémy Bourenne
BACKGROUND: Neuromuscular blocking agents (NMBAs) have been shown to improve the outcome of the most severely hypoxemic, acute respiratory distress syndrome (ARDS) patients. However, the recommended dosage as well as the necessity of monitoring the neuromuscular block is unknown. We aimed to evaluate the efficiency of a nurse-directed protocol of NMBA administration based on a train-of-four (TOF) assessment to ensure a profound neuromuscular block and decrease cisatracurium consumption compared to an elevated and constant dose regimen...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28760798/protocol-for-a-randomised-crossover-trial-to-evaluate-patient-and-nurse-satisfaction-with-electronic-and-elastomeric-portable-infusion-pumps-for-the-continuous-administration-of-antibiotic-therapy-in-the-home-the-comparing-home-infusion-devices-chid-study
#18
Jodie G Hobbs, Melissa K Ryan, Brett Ritchie, Janet K Sluggett, Andrew J Sluggett, Lucy Ralton, Karen J Reynolds
INTRODUCTION: Previous studies comparing satisfaction with electronic and elastomeric infusion pumps are limited, and improvements in size and usability of electronic pumps have since occurred. The Comparing Home Infusion Devices (CHID) study plans to assess patient and nurse satisfaction with an elastomeric and electronic pump for delivering intravenous antibiotic treatment in the home. Secondary objectives are to determine pump-related complications and actual antibiotic dose administered, evaluate temperature variation and compare pump operating costs...
July 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28754600/building-blocks-for-institutional-preparation-of-ctl019-delivery
#19
REVIEW
Joseph McGuirk, Edmund K Waller, Muna Qayed, Sunil Abhyankar, Solveig Ericson, Peter Holman, Christopher Keir, G Douglas Myers
Chimeric antigen receptor (CAR) T-cell therapy is an investigational immunocellular therapy that reprograms a patient's cytotoxic T cells to engage and eliminate malignant cells. CAR T-cell therapies targeting the CD19 antigen have demonstrated high efficacy in clinical trials for patients with B-cell malignancies and may potentially be available on a broader scale in the future. CAR T-cell therapy begins with the collection of a sufficient number of T cells from a patient's peripheral blood through leukapheresis...
July 25, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28738039/chemotherapy-extravasation-establishing-a-national-benchmark-for-incidence-among-cancer-centers
#20
Jeannette Jackson-Rose, Judith Del Monte, Adrienne Groman, Linda S Dial, Leah Atwell, Judy Graham, Rosemary O'Neil Semler, Maryellen O'Sullivan, Lisa Truini-Pittman, Terri A Cunningham, Lisa Roman-Fischetti, Eileen Costantinou, Chris Rimkus, Adrienne J Banavage, Barbara Dietz, Carol J Colussi, Kimberly Catania, Michelle Wasko, Kevin A Schreffler, Colleen West, Mary Lou Siefert, Robert David Rice
BACKGROUND: Given the high-risk nature and nurse sensitivity of chemotherapy infusion and extravasation prevention, as well as the absence of an industry benchmark, a group of nurses studied oncology-specific nursing-sensitive indicators. 
. OBJECTIVES: The purpose was to establish a benchmark for the incidence of chemotherapy extravasation with vesicants, irritants, and irritants with vesicant potential.
. METHODS: Infusions with actual or suspected extravasations of vesicant and irritant chemotherapies were evaluated...
August 1, 2017: Clinical Journal of Oncology Nursing
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