keyword
MENU ▼
Read by QxMD icon Read
search

O

keyword
https://www.readbyqxmd.com/read/28239970/atmospheric-pressure-chemical-ionization-of-explosives-induced-by-soft-x-radiation-in-ion-mobility-spectrometry-mass-spectrometric-investigation-of-the-ionization-reactions-of-drift-gasses-dopants-and-alkyl-nitrates
#1
Daniel Riebe, Alexander Erler, Thomas Ritschel, Toralf Beitz, Hans-Gerd Löhmannsröben, Andreas Beil, Michael Blaschke, Thomas Ludwig
A promising replacement for the radioactive sources commonly encountered in ion mobility spectrometers is a miniaturized, energy-efficient photoionization source that produce the reactant ions via soft X-radiation (2.8 keV). In order to successfully apply the photoionization source, it is imperative to know the spectrum of reactant ions and the subsequent ionization reactions leading to the detection of analytes. To that end, an ionization chamber based on the photoionization source that reproduces the ionization processes in the ion mobility spectrometer and facilitates efficient transfer of the product ions into a mass spectrometer was developed...
August 2016: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28239937/smoking-does-not-influence-disability-accumulation-in-primary-progressive-multiple-sclerosis
#2
O Javizian, L M Metz, S Deighton, M W Koch
BACKGROUND AND PURPOSE: The modifiable risk factor cigarette smoking has been associated with an increased risk of developing multiple sclerosis (MS) and with disease activity in relapsing-remitting MS. However, less is known about the effect of smoking on disease progression in progressive MS. Here the association between cigarette smoking and disability accumulation in primary progressive MS (PPMS) is investigated. METHODS: Kaplan-Meier survival analyses and Cox proportional hazard modelling were used to investigate the influence of cigarette smoking on the risk of reaching Expanded Disability Status Scale (EDSS) 4 and 6 as well as the time from EDSS 4 to 6 in patients with PPMS...
February 26, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28239936/the-cancer-care-experiences-of-gay-lesbian-and-bisexual-patients-a-secondary-analysis-of-data-from-the-uk-cancer-patient-experience-survey
#3
N J Hulbert-Williams, C O Plumpton, P Flowers, R McHugh, R D Neal, J Semlyen, L Storey
Understanding the effects of population diversity on cancer-related experiences is a priority in oncology care. Previous research demonstrates inequalities arising from variation in age, gender and ethnicity. Inequalities and sexual orientation remain underexplored. Here, we report, for the first time in the UK, a quantitative secondary analysis of the 2013 UK National Cancer Patient Experience Survey which contains 70 questions on specific aspects of care, and six on overall care experiences. 68,737 individuals responded, of whom 0...
February 27, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28239877/feeding-range-of-age-1-year-eurasian-perch-perca-fluviatilis-in-the-baltic-sea
#4
I Ahlbeck Bergendahl, P B Holliland, S Hansson, O Karlöf
Using the widespread Eurasian perch Perca fluviatilis as a model organism, feeding ranges were investigated using stable-isotope ratios (δ(15) N and δ(13) C) and body condition. Differences were found between closely located sampling sites in a littoral area without obvious migration barriers, indicating that individual fish had small feeding ranges. Body condition differences between sampled stations were consistent over 4 years. Such sedentary behaviour is important to consider in, e.g. fisheries management and environmental monitoring, as local catch regulations may be meaningful or geographic stability in sampling locations may reduce noise in data...
February 27, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28239867/inpatient-cost-analysis-for-treatment-of-myasthenia-gravis
#5
Jacklyn O Omorodion, Jesse M Pines, Henry J Kaminski
INTRODUCTION: We explored trends in U.S. inpatient costs of care over a 10-year period. METHODS: We compared myasthenia gravis (MG) to multiple sclerosis (MS) and overall U.S. hospital admissions using the Agency for Healthcare Research and Quality Nationwide Inpatient Sample database for 2003-2013. RESULTS: Total costs of MG inpatient care rose 13-fold from 2003-2013. This was accounted for by a >6-fold increase in discharges and a >2-fold increase in cost per discharge...
February 27, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28239809/association-between-the-plasma-levels-of-ima-and-coronary-atherosclerotic-plaque-burden-and-ischemic-burden-in-early-phase-of-non-st-segment-elevation-acute-coronary-syndromes
#6
T Turan, A R Akyüz, S Sahin, S Kul, A S Yilmaz, F Kara, S O Mentese, A Ç Aykan, S Demir, S Celik, S C Karahan
OBJECTIVE: Ischemia-modified albumin (IMA), a novel biochemical marker, is known to reflect ischemia in early phases of acute coronary syndrome (ACS). In the present study, we evaluated the role of IMA on the prediction of coronary atherosclerotic plaque burden and ischemic burden in patients with non-ST-segment-elevation acute coronary syndromes (NSTEACS). PATIENTS AND METHODS: Ninety-six consecutive NSTEACS patients presented within the first three hours of symptom onset were prospectively enrolled in this study...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239798/effect-of-fibroblast-like-cells-of-mesenchymal-origin-of-cytotoxic-activity-of-lymphocytes-against-nk-sensitive-target-cells
#7
A Yu Lupatov, Ya S Kim, O A Bystrykh, I V Vakhrushev, S V Pavlovich, K N Yarygin, G T Sukhikh
We studied immunosuppressive properties of skin fibroblasts and mesenchymal stromal cells against NK cells. In vitro experiments showed that mesenchymal stromal cells isolated from human umbilical cord and human skin fibroblasts can considerably attenuate cytotoxic activity of NK cells against Jurkat cells sensitive to NK-mediated lysis. NK cells cultured in lymphocyte population exhibited higher cytotoxic activity than isolated NK cells. Mesenchymal stromal cells or fibroblasts added 1:1 to lymphocyte culture almost completely suppressed NK cell cytotoxicity...
February 27, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28239795/antiproliferative-activity-of-a-new-nitrosyl-iron-complex-with-cysteamine-in-human-tumor-cells-in-vitro
#8
O S Zhukova, Z S Smirnova, I O Chikileva, M V Kiselevskii
We studied cytotoxic activity of a new NO-releasing tetranitrosyl binuclear iron complex with cysteamine (CysAm) for human tumor cells, the relationship between the expression of O6-methylguanine-DNA methyltransferase (MGMT) and cell sensitivity to CysAm, and apoptosis-inducing capacity of this preparation. It was found that histogenetically different cell lines are characterized by different sensitivity to CysAm, and this parameter correlated with the basal level of MGMT. CysAm induced apoptosis via activation of caspases 3 and 7...
February 27, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28239789/impairment-of-energy-dependent-processes-in-the-muscle-tissue-as-a-pathogenetic-mechanism-of-statin-induced-myopathy
#9
Z I Mikashinovich, E S Belousova, O G Sarkisyan
Administration of simvastatin was followed by a decrease in activities of superoxide dismutase and cytochrome oxidase in rat mitochondria, which attested to dysfunction of the respiratory chain. The decrease in total ATPase and Ca(2+)-ATPase activities in muscle tissue homogenates reflected impaired transport of active cations essential for muscle contraction. We conclude that abnormal relationships in the system of energy synthetic and energy-dependent processes in myocytes serve as the molecular basis for the formation of statin-induced degenerative changes...
February 27, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28239772/a-relationship-between-early-language-skills-and-adult-autistic-like-traits-evidence-from-a-longitudinal-population-based-study
#10
Rebecca Armstrong, Andrew J O Whitehouse, James G Scott, David A Copland, Katie L McMahon, Sophie Fleming, Wendy Arnott
The current study examined the relationship between early language ability and autistic-like traits in adulthood, utilising data from 644 participants from a longitudinal study of the general population. Language performance at 2 years was measured with the Language Development Survey (LDS), and at 20 years the participants completed the Autism-Spectrum Quotient (AQ). Vocabulary size at 2 years was negatively associated with Total AQ score, as well as scores on the Communication, and Social Skills subscales...
February 27, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28239733/evidence-of-robust-participation-by-an-equatorial-4-o-group-in-glycosylation-on-a-2-azido-2-deoxy-glucopyranosyl-donor
#11
Dongming Yao, Yichu Liu, Shiqiang Yan, Yingxia Li, Chun Hu, Ning Ding
Although there are numerous claims of remote group participation leading to the synthesis of the expected glycosides with improved anomeric geometry outcome in glycosylation, there is still a lack of enough strong evidence and this has led to a long-term debate, particularly for equatorial 4-O group participation. In this work, we were able to synthesize and isolate a stable seven-membered trichlorooxazepine ring bridging intermediate with a high yield by employing a 2-azido-2-deoxy-glucopyranosyl donor, which provides strong evidence to support the putative participation of the equatorial 4-O group in glycosylation...
February 27, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28239728/chemistry-of-cs2-and-scnph-adducts-of-the-pyramidal-phosphinidene-bridged-complex-mo2cp-%C3%AE-%C3%AE%C2%BA-1-%C3%AE%C2%BA-1-%C3%AE-5-pc5h4-co-2-%C3%AE-6-hmes-pme3
#12
Isabel G Albuerne, M Angeles Alvarez, M Esther García, Daniel García-Vivó, Miguel A Ruiz
The title complex reacted readily with CS2 and SCNPh to give the phosphinidene-cumulene adducts [Mo2Cp{μ-κ(1)P:κ(1)S,η(5)-P(CS2)C5H4}(CO)2(η(6)-HMes*)(PMe3)] and [Mo2Cp{μ-κ(1)P:κ(1)S,η(5)-P(C(NPh)S)C5H4}(CO)2(η(6)-HMes*)(PMe3)] respectively (Mes* = 2,4,6-C6H2(t)Bu3), as a result of the formal insertion of the C[double bond, length as m-dash]S bond of the heterocumulene into the metallocene Mo-P bond of the phosphinidene complex. The newly formed species bear a pyramidal P atom with a lone electron pair involved in fast inversion, and displayed strong nucleophilicity which enabled easy addition at the P site of carbon-based electrophiles and chalcogen atoms, while the uncoordinated S and N atoms were also competitive nucleophilic sites in these complexes...
February 27, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28239711/interfacial-defects-induced-electronic-property-transformation-at-perovskite-srvo3-srtio3-and-lacro3-srtio3-heterointerfaces
#13
Junjie Li, Deqiang Yin, Qiang Li, Rong Sun, Sumei Huang, Fanzhi Meng
Unravelling the atomic structure and chemical species of interfacial defects is critical to understanding the origin of interfacial properties in many heterojunctions. Here, by combining advanced transmission electron microscopy, spectroscopy and first-principles calculations, we demonstrate interfacial Ti diffusion in SrVO3/SrTiO3 and LaCrO3/SrTiO3 heterointerfaces and uncover that the interfacial defects induce a significant change in electronic properties by showing an electronic transformation from the insulating state to metallic state at SrVO3/SrTiO3 heterointerfaces due to the hybridization of interfacial Ti d, O p and V d, and a metallic to insulating state transformation at LaCrO3/SrTiO3 because of Ti-Cr mixing induced charge redistribution in the interfacial layer...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28239706/structure-and-dynamic-nmr-behavior-of-rhodium-complexes-supported-by-lewis-acidic-group-13-metallatranes
#14
James T Moore, Nicholas E Smith, Connie C Lu
Monovalent Rh was installed into the group 13 metallatranes, M[N(o-(NCH2P((i)Pr)2)C6H4)3] (where M = Al and Ga, abbreviated as ML) to generate Rh → M bonds in the parent complexes, Cl-RhAlL (1-Cl) and Cl-RhGaL (2-Cl). The electron-withdrawing nature of the group 13 metalloids was probed by cyclic voltammetry, and Rh-Ga was found to be more electron-deficient than Rh-Al (Epc = -2.07 and -1.95 V vs. Fc(+)/Fc for 1-Cl and 2-Cl, respectively). Both 1-Cl and 2-Cl were further functionalized through metathesis reactions using MeLi to generate 1-CH3 and 2-CH3, respectively, or using LiHBEt3 to form 1-H and 2-H, respectively...
February 27, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28239698/beneficial-effects-of-apple-peel-polyphenols-on-vascular-endothelial-dysfunction-and-liver-injury-in-high-choline-fed-mice
#15
Mengfan Jia, Daoyuan Ren, Yan Nie, Xingbin Yang
This study was designed to investigate the preventive effects of Red Fuji apple peel polyphenolic extract (APP) on vascular endothelial dysfunction and liver injury in mice fed a high choline diet. The mice were fed 3% dietary choline in drinking water for 8 weeks and displayed vascular dysfunction and liver damage (p < 0.01). The administration of APP at 600 and 900 mg per kg bw significantly elevated serum NO, HDL and 6-Keto-PGF1a levels and lowered serum TC, TG, LDL, ET-1 and TXB2 levels in the HC-fed mice...
February 27, 2017: Food & Function
https://www.readbyqxmd.com/read/28239693/metal-passivated-pbs-nanoparticles-fabrication-and-characterization
#16
M Tchaplyguine, M-H Mikkelä, E Mårsell, C Polley, A Mikkelsen, W Zhang, A Yartsev, C J D Hetherington, L R Wallenberg, O Björneholm
Organic-shell-free PbS nanoparticles have been produced in the size range relevant for quantum-dot solar cells (QDSCs) by a vapor aggregation method involving magnetron reactive sputtering. This method creates a beam of free 5-10 nm particles in a vacuum. The dimensions of the particles were estimated after their deposition on a substrate by imaging them using ex situ SEM and HRTEM electron microscopy. The particle structure and chemical composition could be deduced "on the fly", prior to deposition, using X-ray photoelectron spectroscopy (XPS) with tunable synchrotron radiation...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28239692/high-throughput-screening-of-microchip-synthesized-genes-in-programmable-double-emulsion-droplets
#17
H F Chan, S Ma, J Tian, K W Leong
The rapid advances in synthetic biology and biotechnology are increasingly demanding high-throughput screening technology, such as screening of the functionalities of synthetic genes for optimization of protein expression. Compartmentalization of single cells in water-in-oil (W/O) emulsion droplets allows screening of a vast number of individualized assays, and recent advances in automated microfluidic devices further help realize the potential of droplet technology for high-throughput screening. However these single-emulsion droplets are incompatible with aqueous phase analysis and the inner droplet environment cannot easily communicate with the external phase...
February 27, 2017: Nanoscale
https://www.readbyqxmd.com/read/28239575/observations-on-tympanic-membrane-perforations-safe-type-and-hearing-loss
#18
Sushil Gaur, O N Sinha, Ashesh Bhushan, Gaurav Batni
The most commonly observed clinical findings in otological practice is discharging ear in which perforation of the tympanic membrane is the commonest, yet the patients hardly ever seek advice for deafness as the presenting symptom. In patients with the symptoms of ear ache or ear discharge when relieved seldom present for follow up and are not very much concerned about the hearing loss present there. There is a different correlation between surface area of tympanic membrane and amplification of sound. Conductive hearing loss is seen in lower tones than higher tones...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239450/erratum-to-scaling-up-strategies-of-the-chronic-respiratory-disease-programme-of-the-european-innovation-partnership-on-active-and-healthy-ageing-action-plan-b3-area-5
#19
J Bousquet, J Farrell, G Crooks, P Hellings, E H Bel, M Bewick, N H Chavannes, J Correia de Sousa, A A Cruz, T Haahtela, G Joos, N Khaltaev, J Malva, A Muraro, M Nogues, S Palkonen, S Pedersen, C Robalo-Cordeiro, B Samolinski, T Strandberg, A Valiulis, A Yorgancioglu, T Zuberbier, A Bedbrook, W Aberer, M Adachi, A Agusti, C A Akdis, M Akdis, J Ankri, A Alonso, I Annesi-Maesano, I J Ansotegui, J M Anto, S Arnavielhe, H Arshad, C Bai, I Baiardini, C Bachert, A K Baigenzhin, C Barbara, E D Bateman, B Beghé, A Ben Kheder, K S Bennoor, M Benson, K C Bergmann, T Bieber, C Bindslev-Jensen, L Bjermer, H Blain, F Blasi, A L Boner, M Bonini, S Bonini, S Bosnic-Anticevitch, L P Boulet, R Bourret, P J Bousquet, F Braido, A H Briggs, C E Brightling, J Brozek, R Buhl, P G Burney, A Bush, F Caballero-Fonseca, D Caimmi, M A Calderon, P M Calverley, P A M Camargos, G W Canonica, T Camuzat, K H Carlsen, W Carr, A Carriazo, T Casale, A M Cepeda Sarabia, L Chatzi, Y Z Chen, R Chiron, E Chkhartishvili, A G Chuchalin, K F Chung, G Ciprandi, I Cirule, L Cox, D J Costa, A Custovic, R Dahl, S E Dahlen, U Darsow, G De Carlo, F De Blay, T Dedeu, D Deleanu, E De Manuel Keenoy, P Demoly, J A Denburg, P Devillier, A Didier, A T Dinh-Xuan, R Djukanovic, D Dokic, H Douagui, G Dray, R Dubakiene, S R Durham, M S Dykewicz, Y El-Gamal, R Emuzyte, L M Fabbri, M Fletcher, A Fiocchi, A Fink Wagner, J Fonseca, W J Fokkens, F Forastiere, P Frith, M Gaga, A Gamkrelidze, J Garces, J Garcia-Aymerich, B Gemicioğlu, J E Gereda, S González Diaz, M Gotua, I Grisle, L Grouse, Z Gutter, M A Guzmán, L G Heaney, B Hellquist-Dahl, D Henderson, A Hendry, J Heinrich, D Heve, F Horak, J O' B Hourihane, P Howarth, M Humbert, M E Hyland, M Illario, J C Ivancevich, J R Jardim, E J Jares, C Jeandel, C Jenkins, S L Johnston, O Jonquet, K Julge, K S Jung, J Just, I Kaidashev, M R Khaitov, O Kalayci, A F Kalyoncu, T Keil, P K Keith, L Klimek, B Koffi N'Goran, V Kolek, G H Koppelman, M L Kowalski, I Kull, P Kuna, V Kvedariene, B Lambrecht, S Lau, D Larenas-Linnemann, D Laune, L T T Le, P Lieberman, B Lipworth, J Li, K Lodrup Carlsen, R Louis, W MacNee, Y Magard, A Magnan, B Mahboub, A Mair, I Majer, M J Makela, P Manning, S Mara, G D Marshall, M R Masjedi, P Matignon, M Maurer, S Mavale-Manuel, E Melén, E Melo-Gomes, E O Meltzer, A Menzies-Gow, H Merk, J P Michel, N Miculinic, F Mihaltan, B Milenkovic, G M Y Mohammad, M Molimard, I Momas, A Montilla-Santana, M Morais-Almeida, M Morgan, R Mösges, J Mullol, S Nafti, L Namazova-Baranova, R Naclerio, A Neou, H Neffen, K Nekam, B Niggemann, G Ninot, T D Nyembue, R E O'Hehir, K Ohta, Y Okamoto, K Okubo, S Ouedraogo, P Paggiaro, I Pali-Schöll, P Panzner, N Papadopoulos, A Papi, H S Park, G Passalacqua, I Pavord, R Pawankar, R Pengelly, O Pfaar, R Picard, B Pigearias, I Pin, D Plavec, D Poethig, W Pohl, T A Popov, F Portejoie, P Potter, D Postma, D Price, K F Rabe, F Raciborski, F Radier Pontal, S Repka-Ramirez, S Reitamo, S Rennard, F Rodenas, J Roberts, J Roca, L Rodriguez Mañas, C Rolland, M Roman Rodriguez, A Romano, J Rosado-Pinto, N Rosario, L Rosenwasser, M Rottem, D Ryan, M Sanchez-Borges, G K Scadding, H J Schunemann, E Serrano, P Schmid-Grendelmeier, H Schulz, A Sheikh, M Shields, N Siafakas, Y Sibille, T Similowski, F E R Simons, J C Sisul, I Skrindo, H A Smit, D Solé, T Sooronbaev, O Spranger, R Stelmach, P J Sterk, J Sunyer, C Thijs, T To, A Todo-Bom, M Triggiani, R Valenta, A L Valero, E Valia, E Valovirta, E Van Ganse, M van Hage, O Vandenplas, T Vasankari, B Vellas, J Vestbo, G Vezzani, P Vichyanond, G Viegi, C Vogelmeier, T Vontetsianos, M Wagenmann, B Wallaert, S Walker, D Y Wang, U Wahn, M Wickman, D M Williams, S Williams, J Wright, B P Yawn, P K Yiallouros, O M Yusuf, A Zaidi, H J Zar, M E Zernotti, L Zhang, N Zhong, M Zidarn, J Mercier
[This corrects the article DOI: 10.1186/s13601-016-0116-9.].
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28239332/characterization-of-the-circumlimbal-suture-model-of-chronic-iop-elevation-in-mice-and-assessment-of-changes-in-gene-expression-of-stretch-sensitive-channels
#20
Da Zhao, Christine T O Nguyen, Vickie H Y Wong, Jeremiah K H Lim, Zheng He, Andrew I Jobling, Erica L Fletcher, Holly R Chinnery, Algis J Vingrys, Bang V Bui
To consider whether a circumlimbal suture can be used to chronically elevate intraocular pressure (IOP) in mice and to assess its effect on retinal structure, function and gene expression of stretch sensitive channels. Anesthetized adult C57BL6/J mice had a circumlimbal suture (10/0) applied around the equator of one eye. In treated eyes (n = 23) the suture was left in place for 12 weeks whilst in sham control eyes the suture was removed at day two (n = 17). Contralateral eyes served as untreated controls. IOP was measured after surgery and once a week thereafter...
2017: Frontiers in Neuroscience
keyword
keyword
6117
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"